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Specialty: Dermatology

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Total 354 results found since Jan 2013.

Hidradenitis suppurativa and association with stroke: Systematic review and meta-analysis
J Dermatolog Treat. 2021 Jul 21:1-25. doi: 10.1080/09546634.2021.1959502. Online ahead of print.ABSTRACTHidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterized by painful nodules, abscesses, sinus tract formation and scarring. The relationship between HS and strokes is not well established. To assess this potential association, a systematic review and meta-analysis was performed according to PRISMA guidelines. Electronic searches were performed from six online databases. All eligible case-control studies comparing patients with HS versus non-HS were included. All studies must have included eith...
Source: Journal of Dermatological Treatment - July 22, 2021 Category: Dermatology Authors: Kevin Phan William Hao Syuen Ng Belinda Lai Amit Garg Saxon D Smith Source Type: research

Dermatomyositis is associated with an increased risk of cardiovascular and cerebrovascular events: a Taiwanese population-based longitudinal follow-up study.
CONCLUSIONS: These findings suggest that DMS is associated with an increased risk of cardiovascular and cerebrovascular events. PMID: 23330740 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - January 21, 2013 Category: Dermatology Authors: Lai YT, Dai YS, Yen MF, Chen LS, Chen HH, Cooper RG, Pan SL Tags: Br J Dermatol Source Type: research

Cardiovascular morbidity and mortality in psoriasis and psoriatic arthritis: a systematic literature review
Abstract Previous epidemiological studies have demonstrated a high prevalence of cardiovascular (CV) risk factors in psoriasis patients, including metabolic syndrome, cigarette smoking, obesity, hypertension, diabetes mellitus, insulin resistance and dyslipidaemia. An increase in CV morbidity and mortality attributable to psoriasis is still under question. Primary objective: to assess CV morbidity and mortality in psoriasis and psoriatic arthritis (PsA) including stroke, coronary artery disease, myocardial infarction (MI) and peripheral artery disease. Secondary objectives: to assess if psoriasis per se is an independent C...
Source: Journal of the European Academy of Dermatology and Venereology - July 11, 2013 Category: Dermatology Authors: C. Horreau, C. Pouplard, E. Brenaut, T. Barnetche, L. Misery, B. Cribier, D. Jullien, S. Aractingi, F. Aubin, P. Joly, M. Maître, J.‐P. Ortonne, C. Paul, M.‐A. Richard Tags: Review Article Source Type: research

Dermatomyositis is associated with an increased risk of cardiovascular and cerebrovascular events: a Taiwanese population‐based longitudinal follow‐up study
ConclusionsThese findings suggest that DMS is associated with an increased risk of cardiovascular and cerebrovascular events.
Source: British Journal of Dermatology - January 1, 2013 Category: Dermatology Authors: Y.‐T. Lai, Y.‐S. Dai, M.‐F. Yen, L.‐S. Chen, H.‐H. Chen, R.G. Cooper, S.‐L. Pan Tags: Original Article Source Type: research

Neurological diseases and bullous pemphigoid: A case & #8211;control study in Iranian patients
Conclusions: Neurological diseases in general, and stroke and dementia in particular, were significantly associated with bullous pemphigoid in our study.
Source: Indian Journal of Dermatology, Venereology and Leprology - February 2, 2017 Category: Dermatology Authors: Maryam Daneshpazhooh Javad Khorassani Kamran Balighi Narges Ghandi Hamidreza Mahmoudi Hamidreza Tohidinik Shahin Hamzelou Cheyda Chams-Davatchi Source Type: research

The immunocompromised district in dermatology: A unifying pathogenic view of the regional immune dysregulation
Abstract: Besides the systemic immune deficiency, a sectorial default in immune control may occur in immunocompetent subjects. This regional immune defect can appear and remain confined to differently damaged skin areas, lately labeled immunocompromised districts (ICDs).An ICD is a skin area more vulnerable than the rest of the body for genetic or acquired reasons. Its vulnerability mainly consists in a local dysregulation of the immune control, which often facilitates (but sometimes hinders) the local onset of immunity-related eruptions or skin disorders.The factors responsible for localized immune dysregulation are multi...
Source: Clinics in Dermatology - August 25, 2014 Category: Dermatology Authors: Vincenzo Ruocco, Eleonora Ruocco, Vincenzo Piccolo, Giampiero Brunetti, Luigi Pio Guerrera, Ronni Wolf Source Type: research

Morbidity and Causes of Death in Patients with Cutaneous T-cell Lymphoma in Finland.
Abstract Cutaneous T-cell lymphomas (CTCL), especially mycosis fungoides, can be considered as a state of longstanding low-grade systemic inflammation. Many studies have focused on secondary cancers with CTCL, but information about comorbidities is limited. A total of 144 patients with CTCL at Helsinki University Central Hospital during 2005 to 2015 were studied to determine associated comorbidities and causes of death in this cohort. Compared with an age-standardized control population, the prevalence of type 2 diabetes mellitus was increased among patients with CTCL with no link to obesity. Patients with CTCL ha...
Source: Acta Dermato-Venereologica - February 7, 2017 Category: Dermatology Authors: Väkevä L, Lipsanen T, Sintonen H, Ranki A Tags: Acta Derm Venereol Source Type: research

Psoriasis and cardiovascular events: updating the evidence
In conclusion, this updated meta-analysis confirmed that patients with psoriasis have an increased risk of CVD, especially those with severe psoriasis.
Source: Archives of Dermatological Research - February 16, 2017 Category: Dermatology Source Type: research

Prognostic factors for mortality in patients with bullous pemphigoid: a meta-analysis
This study indicated that BP patients with older age, circulating antibodies, dementia, and stroke are at greater risk of mortality. Clinicians should be aware of this association and utilize this information in patient education and treatment process.
Source: Archives of Dermatological Research - March 18, 2017 Category: Dermatology Source Type: research

Increased frequency of multiple sclerosis among patients with bullous pemphigoid: a population ‐based cohort study on comorbidities anchored around the diagnosis of bullous pemphigoid
ConclusionsWe discovered a significantly increased frequency of MS among patients with BP. At the time of diagnosis, patients with BP had an excessive number of comorbidities and an increased mortality rate over the following years.
Source: British Journal of Dermatology - April 10, 2017 Category: Dermatology Authors: L. Kibsgaard, M. Rasmussen, A. Lamberg, M. Deleuran, A.B. Olesen, C. Vestergaard Tags: Epidemiology Source Type: research

Mortality and Comorbidity Profiles of Patients with Bullous Pemphigoid in Korea.
Conclusion: The mortality rate of patients with BP is higher than that of the general Korean population. Korean patients with BP are more likely to have dementia, Parkinson's disease, diabetes, and stroke. Risk factors for increased 5-year mortality include old age at the time of diagnosis and medical comorbidities, especially cardiac disease and renal disease. PMID: 29386827 [PubMed]
Source: Annals of Dermatology - February 2, 2018 Category: Dermatology Tags: Ann Dermatol Source Type: research

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: A case of a neurologic disease with a skin-deep diagnosis
We present a 34-year-old woman with history of recurrent migraine headaches and right pontine stroke who presented to our emergency department for intermittent blurry vision and worsening headache.
Source: Journal of the American Academy of Dermatology - August 2, 2018 Category: Dermatology Source Type: research

Association Between Atopic Dermatitis and Cardiovascular Disease: A Nationwide Register-based Case-control Study from Sweden.
In conclusion, in this study, AD was associated with CVD, and this should be kept in mind, especially when managing patients with severe AD. PMID: 31197387 [PubMed - as supplied by publisher]
Source: Acta Dermato-Venereologica - June 13, 2019 Category: Dermatology Authors: Ivert LU, Johansson EK, Dal H, Lindelöf B, Wahlgren CF, Bradley M Tags: Acta Derm Venereol Source Type: research

617 Generation of immortalized sweat gland myoepithelial cells and eccrine sweat gland research model
The increased incidence of heat stroke is caused by reduced sweating as a result of failures in tissue homeostasis that occur with aging. Specifically, tissue homeostasis is disrupted by the exhaustion of stem cells. We previously revealed that myoepithelial cells are the stem cells of sweat glands, thereby heat stroke can be avoided by preventing myoepithelial cell loss. Although myoepithelial cells serve as a useful tool for revealing their depletion, only a single strain of sweat gland cells, NCL-SG3, can differentiate into mature cells in adherent culture conditions.
Source: Journal of Investigative Dermatology - August 31, 2019 Category: Dermatology Authors: T. Hayakawa, R. Kurata, F. Fujita, F. Okada, K. Sekiguchi Tags: Stem Cells, Skin Appendages and Tissue Regeneration Source Type: research

Controversial cardiovascular and hematologic comorbidities in atopic dermatitis
AbstractAtopic dermatitis ’ (AD) systemic involvement is wide-reaching. The cardiovascular and hematological comorbidities of AD have potential for considerable economic and physical burden; however, data surrounding the association between these comorbidities and AD is controversial. This review discusses the cardiovascul ar and hematological comorbidities of AD, detailing the conflicting evidence, pathophysiology, and connection to medications. A PubMed search was conducted for studies detailing the association of cardiovascular and hematological comorbidities with AD, providing approximately 30 results. Additional sea...
Source: Archives of Dermatological Research - May 10, 2021 Category: Dermatology Source Type: research