Filtered By:
Specialty: Infectious Diseases

This page shows you your search results in order of relevance. This is page number 19.

Order by Relevance | Date

Total 484 results found since Jan 2013.

Soluble suppression of tumorigenicity 2 levels are not predictive of non-AIDS events during antiretroviral therapy-mediated viral suppression
Before initiation of antiretroviral therapy (ART), levels of soluble suppression of tumorigenicity 2 (sST2) were not elevated in people living with HIV who later developed non-AIDS events (including myocardial infarction and stroke), compared with controls. However, higher sST2 levels measured pre-ART were a significant predictor of death while on ART. Future studies should explore the potential of sST2 to serve as a short-term predictor of non-AIDS events during viral suppression.
Source: AIDS - June 3, 2019 Category: Infectious Diseases Tags: Research Letters Source Type: research

Correlates of HIV RNA concentrations in cerebrospinal fluid during antiretroviral therapy: a longitudinal cohort study
Publication date: Available online 14 June 2019Source: The Lancet HIVAuthor(s): Alessandro Livelli, Florin Vaida, Ronald J Ellis, Qing Ma, Micol Ferrara, David B Clifford, Ann C Collier, Benjamin B Gelman, Christina M Marra, Justin C McArthur, J Allen McCutchan, Susan Morgello, Ned Sacktor, David M Simpson, Igor Grant, Scott L Letendre, Ian Abramson, Muhammad T. Al-Lozi, Sarah L. Archibald, J. Hampton AtkinsonSummaryBackgroundFew large projects have evaluated the factors that influence the HIV RNA concentrations (viral load) in cerebrospinal fluid (CSF) during antiretroviral therapy (ART) over time. We aimed to determine t...
Source: The Lancet HIV - June 16, 2019 Category: Infectious Diseases Source Type: research

Chronic conditions -- not infectious diseases -- are top 5 causes of early death in China
(Institute for Health Metrics and Evaluation) Chronic diseases, such as stroke, ischemic heart disease, and lung cancer, now represent the leading causes of premature death in China, according to a new scientific study. The rise in non-communicable diseases reflects declines in maternal and child mortality over nearly three decades, largely the result of economic growth and increasing levels of education. In addition, China has instituted national programs targeting infectious diseases.
Source: EurekAlert! - Infectious and Emerging Diseases - June 24, 2019 Category: Infectious Diseases Source Type: news

Aspergillus fumigatus endocarditis in a splenectomized patient with no risk factors
Publication date: Available online 9 January 2020Source: IDCasesAuthor(s): Abhimanyu Aggarwal,, Karen Hogan,, Armando Paez,AbstractAspergillus endocarditis is a rare cause of culture-negative fungal endocarditis, after Candida endocarditis. Typical risk factors include intravenous drug use, immunosuppression, prior cardiac surgery or presence of prosthetic heart valves, hematopoietic stem cell or solid organ transplantation. Common presentations include signs and symptoms consistent with endocarditis but with negative bacterial blood cultures. Here, we present a case report of a 49-year-old male without known risk factors ...
Source: IDCases - January 9, 2020 Category: Infectious Diseases Source Type: research

A classic and fatal case of Streptococcus mutans subacute bacterial endocarditis; A now potentially underappreciated disease
We describe a patient found to have Streptococcus mutans subacute bacterial endocarditis, who presented with classic risk factors and findings, and who died shortly after presentation due to hemorrhagic conversion of an embolic stroke in the setting of anticoagulation. It is critical that all cases of streptococcal bacteremia be appropriately evaluated and treated, and that Streptococcus spp. not ever be routinely considered a blood culture ‘contaminant’.
Source: IDCases - January 12, 2020 Category: Infectious Diseases Source Type: research

Left-sided infective endocarditis in persons who inject drugs
ConclusionsLSIE in PWID is not uncommon. Compared to non-LSIE in PWID, valve surgery is more common and mortality is higher. For reasons that are unclear, stroke is more frequent in LSIE in PWID than in non-PWID with LSIE but mortality is no different.
Source: Infection - February 24, 2020 Category: Infectious Diseases Source Type: research

Nasal colonization with Staphylococcus aureus is a risk factor for ventricular assist device infection in the first year after implantation: a prospective, single-centre, cohort study
The prevalence of heart failure is rising1, 2 thus constantly widening the gap between donor hearts and patients listed for transplantation3. For an increasing number of patients with advanced heart failure, durable ventricular assist devices (VAD) prolong survival and improve quality of life4 by serving as bridge to transplant, or, for those not eligible for heart transplantation, as destination therapy, i.e. as a life-long support4, 5. Their long-term use, however, is hampered by stroke, bleeding, and infection.
Source: Journal of Infection - February 25, 2020 Category: Infectious Diseases Authors: Dennis Nurjadi, Katharina Last, Sabrina Klein, S ébastien Boutin, Bastian Schmack, Florian Mueller, Klaus Heeg, Arjang Ruhparwar, Alexandra Heininger, Philipp Zanger Source Type: research

Presence of asymptomatic cytomegalovirus and Epstein--Barr virus DNA in blood of persons with HIV starting antiretroviral therapy is associated with non-AIDS clinical events
Background: Even with antiretroviral therapy (ART), persons with HIV (PWH) experience increased morbidity and mortality. Cytomegalovirus (CMV) and Epstein--Barr virus (EBV) co-infections likely exacerbate inflammatory-related diseases. Objective: To determine if presence of detectable CMV or EBV DNA in peripheral blood mononuclear cells (PBMC) is associated with non-AIDS events among PWH receiving modern ART. Design: We performed a case--control study of PWH starting ART and HIV-suppressed at year 1 and thereafter, 140 cases who experienced non-AIDS events and 305 matched controls. Events included myocardial infarc...
Source: AIDS - April 9, 2020 Category: Infectious Diseases Tags: CLINICAL SCIENCE Source Type: research

A Complicated Case of Haemophilus influenzae Endocarditis in an Adult
Bacterial causes for infective endocarditis have changed over the years, with Staphylococcus aureus now being the most common pathogen isolated. With the advent of routine childhood vaccinations, invasive infections caused by Haemophilus influenzae have become rare. We wish to report a case of infective endocarditis caused by H. influenzae that was complicated by meningitis, septic arthritis, and stroke.
Source: Infectious Diseases in Clinical Practice - April 24, 2020 Category: Infectious Diseases Tags: Case Reports Source Type: research

Blood clotting abnormalities reveal COVID-19 patients at risk for thrombotic events
(American College of Surgeons) When researchers from the University of Colorado Anschutz Medical Campus, Aurora, used a combination of two specific blood-clotting tests, they found critically ill patients infected with Coronavirus Disease 2019 (COVID-19) who were at high risk for developing renal failure, venous blood clots, and other complications associated with blood clots, such as stroke.
Source: EurekAlert! - Infectious and Emerging Diseases - May 15, 2020 Category: Infectious Diseases Source Type: news

Acute Cerebral Stroke with Multiple Infarctions and COVID-19, France, 2020
S. Zayet et al.
Source: Emerging Infectious Diseases Journal - May 26, 2020 Category: Infectious Diseases Source Type: research

A rare cause of infective endocarditis and stroke: filamentous vegetation due to Granulicatella adiacens
Source: International Journal of Infectious Diseases - June 2, 2020 Category: Infectious Diseases Authors: Christoffel J. Opperman, Jens Hitzeroth Tags: Medical Imagery Source Type: research

Multiple neurocysticercosis and aneurismal subarachnoid hemorrhage: case presentation and systematic literature review.
Authors: Meregildo ED Abstract Neurocysticercosis (NCC) is a global health problem. In more developed countries, NCC is mainly a disease affecting immigrants. In developing countries, NCC is the most common parasitic disease of the nervous system and the main cause of acquired epilepsy. NCC is also an unrecognized cause of strokes and could account for 4%-12% of strokes. Here, I report a case of a 58-year-old woman who presented to the emergency department (ED) with severe headache, vomiting, and sudden loss of consciousness. Multiple NCC and Fisher grade 4 aneurysmal subarachnoid hemorrhage (SAH) were demonstrated...
Source: Infezioni in Medicina - June 4, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Respiratory Syncytial Virus Outbreak in a Veterans Affairs Long-term Care Facility
Conclusions Respiratory syncytial virus is highly infectious and can easily cause an outbreak in an LTCF. Polymerase chain reaction testing was contributory to identify cases rapidly. Rapid PCR results and intensified infection control measures were instrumental to halt the outbreak.
Source: Infectious Diseases in Clinical Practice - June 24, 2020 Category: Infectious Diseases Tags: Original Articles Source Type: research

Brief Report: Relationship Between Nonalcoholic Fatty Liver Disease and Cardiovascular Disease in Persons With HIV
Background: Nonalcoholic fatty liver disease (NAFLD) and HIV are independently associated with cardiovascular disease (CVD). However, the factors associated with NAFLD in persons living with HIV (PWH) and whether CVD is more frequent in PWH with NAFLD are currently unknown. Methods: From the Partners HealthCare Research Patient Data Registry, we identified PWH with and without NAFLD between 2010 and 2017. NAFLD was defined using validated histological or radiographic criteria. CVD was defined by an ICD-9 diagnosis of coronary artery disease, myocardial infarction, coronary revascularization, peripheral vascular diseas...
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - June 25, 2020 Category: Infectious Diseases Tags: Clinical Science Source Type: research