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Nutrition: Vitamin D

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Total 344 results found since Jan 2013.

Vitamin D deficiency in relation to the poor functional outcomes in nondiabetic patients with ischemic stroke.
Conclusions Vitamin D deficiency is associated with an increased risk of poor functional outcome events in Chinese nondiabetic stroke individuals. PMID: 29437901 [PubMed - as supplied by publisher]
Source: Bioscience Reports - February 5, 2018 Category: Biomedical Science Authors: Wei ZN, Kuang JG Tags: Biosci Rep Source Type: research

Vitamin D 3 Supplementation Reduces Subsequent Brain Injury and Inflammation Associated with Ischemic Stroke
AbstractAcute inflammation can exacerbate brain injury after ischemic stroke. Beyond its well-characterized role in calcium metabolism, it is becoming increasingly appreciated that the active form of vitamin D, 1,25-dihydroxyvitamin D3 (1,25-VitD3), has potent immunomodulatory properties. Here, we aimed to determine whether 1,25-VitD3 supplementation could reduce subsequent brain injury and associated inflammation after ischemic stroke. Male C57Bl6 mice were randomly assigned to be administered either 1,25-VitD3 (100  ng/kg/day) or vehicle i.p. for 5 day prior to stroke. Stroke was induced via middle cerebral artery occl...
Source: NeuroMolecular Medicine - February 23, 2018 Category: Neurology Source Type: research

Association of Fibroblast Growth Factor 23 With Ischemic Stroke and Its Subtypes: A Mendelian Randomization Study
In this study, we aimed to assess the association of FGF23 with ischemic stroke and its subtypes by applying a Mendelian randomization (MR) framework. Five genetic variants obtained from a genome-wide association study involving 16,624 European subjects were used as valid instruments of circulating FGF23 levels. MR was applied to infer the causality of FGF23 levels and the risk of ischemic stroke using data from the MEGASTROKE consortium. Subsequently, several MR analyses, including inverse-variance weighted meta-analysis, MR-Egger, weighted median estimate (WME), MR Pleiotropy Residual Sum and Outlier were performed. The ...
Source: Frontiers in Genetics - December 23, 2020 Category: Genetics & Stem Cells Source Type: research

Association between Fok1 and TaqI polymorphisms of vitamin D receptor gene with the severity of stenosis and calcification in carotid bulb in patients with ischemic stroke
CONCLUSIONS: There may be a biological association between the FokI VDR gene and carotid bulb calcification.PMID:35091316 | DOI:10.1016/j.jocn.2022.01.009
Source: Atherosclerosis - January 29, 2022 Category: Cardiology Authors: Farzaneh Foroughinia Najmeh Morovati Anahid Safari Mehdi Dianatpour Iman Jamhiri Seyed Taghi Heydari Sedighe Hooshmandi Afshin Borhani-Haghighi Source Type: research

The association between the serum vitamin D levels and the stroke lesion size, functional ability, and cognition in elderly Korean ischemic stroke patients
This study included Korean ischemic stroke patients aged 65 to 85 years. The size of the lesion was measured in brain images taken within 24 hours of hospitalization. The level of 25-(OH) Vitamin D (ng/mL), a metabolite of vitamin D, in the serum collected within 48 hours of hospitalization, and the modified Barthel index (MBI), gait performance, the muscle power of hip and knee extensors on the hemiplegic side, and mini-mental status examination (MMSE) were recorded within 1 week of the onset of the disease. Each factor was compared through correlation analysis, and the significance was confirmed using the Spearman correl...
Source: Medicine - September 2, 2022 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Associations of vitamin D-related single nucleotide polymorphisms with post-stroke depression among ischemic stroke population
ConclusionOur findings suggest that the polymorphisms of VitD metabolic pathway genes VDR and CYP27B1 may be associated with PSD in patients with ischemic stroke.
Source: Frontiers in Psychiatry - June 2, 2023 Category: Psychiatry Source Type: research

Increased Serum Levels of IL-1 β after Ischemic Stroke are Inversely Associated with Vitamin D
CONCLUSION: Ischemic stroke correlates positively with IL-1β and negatively with VitD levels. The speculated role of VitD deficiency in the evolution and severity of stroke may be justified by its role in the modification of inflammation.PMID:37431715 | DOI:10.22034/iji.2023.96384.2432
Source: Iranian Journal of Immunology - July 11, 2023 Category: Allergy & Immunology Authors: Mahnaz Bayat Niloufar Razavi Moosavi Najmeh Karimi Moosa Rahimi Afshin Borhani-Haghighi Source Type: research

Relationship between serum vitamin D levels and inflammatory markers in acute stroke patients
ConclusionsSerum vitamin D levels are inversely associated with the levels of interleukin‐6 and hsCRP, suggesting a potential anti‐inflammatory role for vitamin D in stroke individuals. Our study explored the relationship between vitamin D levels and inflammatory markers in acute stroke patients and examined the effect of vitamin D and inflammatory markers on poststroke depression. We found that serum vitamin D levels were negatively associated with serum levels of interleukin‐6, suggesting a potential anti‐inflammatory role for vitamin D. Our results provided evidence for the mechanism of poststroke depression ca...
Source: Brain and Behavior - January 11, 2018 Category: Neurology Authors: Qiongzhang Wang, Zhuoying Zhu, Yuntao Liu, Xinjie Tu, Jincai He Tags: ORIGINAL RESEARCH Source Type: research

Role of vitamin D in the association between pre-stroke sleep quality and poststroke depression and anxiety
CONCLUSION: Decreased serum vitamin D levels at admission are associated with a high risk for PSD and PSA in patients with poor pre-stroke sleep quality during the early stages of AIS.PMID:37542680 | DOI:10.1007/s11325-023-02894-1
Source: Sleep and Breathing - August 5, 2023 Category: Sleep Medicine Authors: Celikbilek Asuman Koysuren Aydan Konar Naime Meric Source Type: research

Vitamin D deficiency is associated with acute ischemic stroke, C-reactive protein, and short-term outcome
AbstractThe aim of this study was to investigate whether vitamin D deficiency (VDD) is associated with acute ischemic stroke, inflammatory markers, and short-term outcome. 168 acute ischemic stroke patients and 118 controls were included. The modified Rankin Scale (mRS) was applied up to 8  h of admission (baseline) and after three-months follow-up, and blood samples were obtained up to 24 h of admission to evaluate serum levels of 25-hydroxivitamin D [25(OH)D] and inflammatory markers. Vitamin D levels classified the individuals in sufficient (VDS ≥ 30.0 ng/mL), insufficient (VDI 20.0–29.9 ng/mL), and deficien...
Source: Metabolic Brain Disease - December 13, 2016 Category: Neurology Source Type: research

The Importance of Educating Patients With Stroke About Vitamin D
ABSTRACT: There is a growing body of evidence linking vitamin D to more than only bone health. Researchers are discovering connections between low vitamin D levels and increased stroke risk, higher mortality, and poorer outcomes after stroke. Nurses need to be aware of ongoing research regarding vitamin D and include information about this important vitamin with patient education, especially for older patients admitted with stroke symptoms or risks.
Source: Journal of Neuroscience Nursing - November 8, 2017 Category: Neuroscience Tags: Clinical Nursing Focus Source Type: research