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Nutrition: Propolis

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Total 26 results found since Jan 2013.

PRospective Observational POLIsh Study on post-stroke delirium (PROPOLIS): methodology of hospital-based cohort study on delirium prevalence, predictors and diagnostic tools
This study is designed to provide information on clinical manifestation, diagnostic methods and determinants of delirium spectrum disorders in acute stroke phase and their short and long-term consequences. Collected information allow us to create a predictive model for post-stroke delirium.
Source: BMC Neurology - June 19, 2015 Category: Neurology Authors: Elzbieta KlimiecTomasz DziedzicKatarzyna KowalskaAleksandra SzyperJoanna PeraPaulina PotoczekAgnieszka SlowikAleksandra Klimkowicz-Mrowiec Source Type: research

Frequency and predictors of post-stroke delirium in PRospective Observational POLIsh Study (PROPOLIS)
AbstractDelirium is the most common and serious neurobehavioral complication in acute hospital admissions. Some patients develop signs of delirium but do not meet all diagnostic criteria. Stroke is a major risk factor for delirium. The aim of this prospective study was to build a predictive model for delirium and subsyndromal post-stroke delirium. Patients with stroke were screened for delirium during the first 7  days after admission. Delirium was diagnosed according to DSM-V criteria. Baseline demographic, biochemical, stroke-related data, medications used, neurological deficit, and premorbid cognitive and functional im...
Source: Journal of Neurology - February 8, 2018 Category: Neurology Source Type: research

Early depression independently of other neuropsychiatric conditions, influences disability and mortality after stroke (research study-part of PROPOLIS Study) - Kowalska K, Krzywosza ński, Droś J, Pasińska P, Wilk A, Klimkowicz-Mrowiec A.
Post-stroke depression (PSD) is the most frequent neuropsychiatric consequence of stroke. The nature of the relationship between PSD and mortality still remains unknown. One hypothesis is that PSD could be more frequent in those patients who are more vulne...
Source: SafetyLit - November 28, 2020 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Transient cognitive impairment in the acute phase of stroke – prevalence, risk factors and influence on long-term prognosis in population of patients with stroke (research study – part of the PROPOLIS study)
This study evaluated the prevalence and risk factors for transient co...
Source: BMC Neurology - February 17, 2023 Category: Neurology Authors: Jakub Dro ś, Katarzyna Kowalska, Paulina Pasińska and Aleksandra Klimkowicz-Mrowiec Tags: Research Source Type: research

Delirium post-stroke: short- and long-term effect on depression, anxiety, apathy and aggression (research study-part of PROPOLIS study) - Kowalska K, Dro ś J, Mazurek M, Pasińska P, Gorzkowska A, Klimkowicz-Mrowiec A.
BACKGROUND: Stroke patients are particularly vulnerable to delirium episodes, but very little is known about its subsequent adverse mental health outcomes. The author's objective was to explore the association between in-hospital delirium and depression, a...
Source: SafetyLit - July 20, 2020 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

Brown propolis attenuates cerebral ischemia-induced oxidative damage via affecting antioxidant enzyme system in mice.
Abstract Oxidative stress plays a critical role in ischemic brain injury. Superoxide dismutase (SOD) and glutathione peroxidase (GPx) are the enzymes underlying the endogenous antioxidant mechanisms affected by stroke and are considered as oxidative stress biomarkers. Brown propolis (BP) is a bioactive natural product with a set of biological activities that in turn may differ depending on the area from which the substance is originated. The aim of this study was to investigate the effect of water-extracted brown propolis (WEBPs), from two regions of Iran, against cerebral ischemia-induced oxidative injury in a mo...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - November 22, 2016 Category: Drugs & Pharmacology Authors: Bazmandegan G, Boroushaki MT, Shamsizadeh A, Ayoobi F, Hakimizadeh E, Allahtavakoli M Tags: Biomed Pharmacother Source Type: research

Dichloromethane extracts of propolis protect cell from oxygen-glucose deprivation-induced oxidative stress via reducing apoptosis.
CONCLUSION: The anti-oxidative effect of propolis can be applied to daily food supplements and may benefit stroke patients. PMID: 27329777 [PubMed]
Source: Food and Nutrition Research - June 24, 2016 Category: Nutrition Authors: Sun LP, Xu X, Hwang HH, Wang X, Su KY, Chen YL Tags: Food Nutr Res Source Type: research

Poststroke Delirium Clinical Motor Subtypes: The PRospective Observational POLIsh Study (PROPOLIS).
Authors: Pasinska P, Kowalska K, Klimiec E, Wilk A, Szyper-Maciejowska A, Dziedzic T, Klimkowicz-Mrowiec A Abstract Although delirium is the most common neurobehavioral complication after stroke, its motor subtypes-hypoactive, hyperactive, mixed, and none-as well as their risk factors are not well characterized. Motor subtypes influence recognition and prognosis of delirium in hospitalized patients. The aim of this prospective study was to assess the frequency of poststroke delirium subtypes and to describe their predictive models. Consecutive patients with stroke were screened for delirium with the Confusion Asses...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - November 9, 2018 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Molecules, Vol. 24, Pages 2323: Advances in Biosynthesis, Pharmacology, and Pharmacokinetics of Pinocembrin, a Promising Natural Small-Molecule Drug
ng Yang Pinocembrin is one of the most abundant flavonoids in propolis, and it may also be widely found in a variety of plants. In addition to natural extraction, pinocembrin can be obtained by biosynthesis. Biosynthesis efficiency can be improved by a metabolic engineering strategy and a two-phase pH fermentation strategy. Pinocembrin poses an interest for its remarkable pharmacological activities, such as neuroprotection, anti-oxidation, and anti-inflammation. Studies have shown that pinocembrin works excellently in treating ischemic stroke. Pinocembrin can reduce nerve damage in the ischemic area and reduce mitochon...
Source: Molecules - June 23, 2019 Category: Chemistry Authors: Xiaoling Shen Yeju Liu Xiaoya Luo Zhihong Yang Tags: Review Source Type: research

The Natural Flavonoid Pinocembrin: Molecular Targets and Potential Therapeutic Applications
Abstract Pinocembrin is a natural flavonoid compound extracted from honey, propolis, ginger roots, wild marjoram, and other plants. In preclinical studies, it has shown anti-inflammatory and neuroprotective effects as well as the ability to reduce reactive oxygen species, protect the blood-brain barrier, modulate mitochondrial function, and regulate apoptosis. Considering these pharmaceutical characteristics, pinocembrin has potential as a drug to treat ischemic stroke and other clinical conditions. In this review, we summarize its pharmacologic characteristics and discuss its mechanisms of action and potential th...
Source: Molecular Neurobiology - March 6, 2015 Category: Neurology Source Type: research

Luteolin: How To Reduce Breast Cancer Risk
More than 100 women die of breast cancer in the U.S. every day. It's the second leading cause of cancer deaths in American women. But in my opinion, many of those women really die of a tragic medical error. Let me explain… Millions of women in the U.S. have taken Big Pharma's hormone replacement therapy (HRT). Their doctors prescribe it to try to relieve the symptoms of menopause. Like hot flashes, night sweats, mood swings and weight gain. But what the drug companies try to pass off as hormones are actually synthetic concoctions. They are fake versions of the estrogen and progesterone that your body makes n...
Source: Al Sears, MD Natural Remedies - June 23, 2017 Category: Complementary Medicine Authors: Al Sears Tags: Anti-Aging Source Type: news

Antithrombotic activity of flavonoids and polyphenols rich plant species.
Abstract Cardiovascular diseases represent one of the most notable health problems of the modern civilization. Stroke and heart attack often lead to lethal outcome; essential problem underneath being thrombus formation. Prophylactic approaches include acetylsalicylic acid and clopidogrel therapy on the level of primary hemostasis, i.e., primary clot formation. In the last five years, in the USA, health care expenses related to cardiovascular diseases have increased 50 %, to over 350 billion dollars. Thus, application of plant species and medicinal plants rich in polyphenols in prevention of thrombus formation are ...
Source: Acta Pharmaceutica - October 23, 2019 Category: Drugs & Pharmacology Authors: Bojić M, Maleš Ž, Antolić A, Babić I, Tomičić M Tags: Acta Pharm Source Type: research

Neuroprotective Potential of Caffeic Acid Phenethyl Ester (CAPE) in CNS Disorders: Mechanistic and Therapeutic Insights
Curr Neuropharmacol. 2021 Jun 8. doi: 10.2174/1570159X19666210608165509. Online ahead of print.ABSTRACTNeurological disorders like Alzheimer's disease (AD), Parkinson's disease (PD), stroke, amyotrophic lateral sclerosis, Huntington's disease (HD), epilepsy, traumatic brain injury (TBI), depression and anxiety are responsible for thousands of deaths worldwide every year. With the increase in life expectancy, there has been a rise in the prevalence of these disorders. Age is one of the major risk factors for these neurological disorders and with the aged population is set to rise to 1.25 billion by 2050. There is a growing ...
Source: Current Neuropharmacology - June 9, 2021 Category: Drugs & Pharmacology Authors: Namrata Pramod Kulkarni Bhupesh Vaidya Acharan Narula Shyam Sunder Sharma Source Type: research