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Specialty: Endocrinology
Nutrition: Diets
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Total 34 results found since Jan 2013.
Pro-Neurotensin/Neuromedin N and Risk of Incident Metabolic Syndrome and Diabetes Mellitus in the REGARDS Cohort
CONCLUSIONS: Pro-NT/NMN was associated with MetS and two components, dysglycemia and low HDL, likely explained by insulin resistance.PMID:34013344 | DOI:10.1210/clinem/dgab355
Source: The Journal of Clinical Endocrinology and Metabolism - May 20, 2021 Category: Endocrinology Authors: Charles D Nicoli April P Carson Timothy B Plante D Leann Long Leslie A McClure Janin Schulte Mary Cushman Source Type: research
Greater macrovascular and microvascular morbidity from type 2 diabetes in northern compared with southern China: A cross‐sectional study
ConclusionsMore macrovascular and microvascular complications were found in northern compared with southern patients, and the largest difference also appeared in the younger age groups<55 years, which might be meaningful to a screening and treatment strategy according to geographic differences.
Source: Journal of Diabetes Investigation - May 3, 2020 Category: Endocrinology Authors: Li Wang,
Ying Xing,
Xinwen Yu,
Jie Ming,
Xiangyang Liu,
Xiaomiao Li,
Jianfang Fu,
Jie Zhou,
Bin Gao,
Dayi Hu,
Changyu Pan,
Linong Ji,
Qiuhe Ji Tags: Original Article Source Type: research
Lead Anti-obesity Compounds from Nature.
Conclusion-Consumption of diets comprising high amounts of active anti-obesity natural compounds is a promising strategy for the suppression of lipid accumulation and adipogenesis in obese individuals.
PMID: 32364084 [PubMed - as supplied by publisher]
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - May 2, 2020 Category: Endocrinology Authors: Dahiya V, Vasudeva N, Sharma S, Kumar A, Rowley D Tags: Endocr Metab Immune Disord Drug Targets Source Type: research
Greater macrovascular and microvascular morbidity from type 2 diabetes in Northern compared with Southern China: a cross ‐sectional study
ConclusionsMore macrovascular and microvascular complications were found in Northern compared to Southern patients, and the largest difference also appeared in the younger age groups under 55, which may be meaningful to a screening and treatment strategy according to geographic differences.
Source: Journal of Diabetes Investigation - March 31, 2020 Category: Endocrinology Authors: Li Wang,
Ying Xing,
Xinwen Yu,
Jie Ming,
Xiangyang Liu,
Xiaomiao Li,
Jianfang Fu,
Jie Zhou,
Bin Gao,
Dayi Hu,
Changyu Pan,
Linong Ji,
Qiuhe Ji Tags: ORIGINAL ARTICLE Source Type: research
AHA News: These Diets Helped Women With Diabetes Cut Heart Attack, Stroke Risk
Title: AHA News: These Diets Helped Women With Diabetes Cut Heart Attack, Stroke RiskCategory: Health NewsCreated: 9/19/2019 12:00:00 AMLast Editorial Review: 9/20/2019 12:00:00 AM
Source: MedicineNet Diabetes General - September 20, 2019 Category: Endocrinology Source Type: news
Vitamin D may increase stroke risk
A large review of studies, published in theAnnals of Internal Medicine, on dietary supplements has not only indicated they have little benefit but also suggests that vitamin D may increase stroke risk. Medscape
Source: Society for Endocrinology - July 10, 2019 Category: Endocrinology Source Type: news
The dietary transition and its association with cardiometabolic mortality among Chinese adults, 1982–2012: a cross-sectional population-based study
Publication date: Available online 10 May 2019Source: The Lancet Diabetes & EndocrinologyAuthor(s): Yuna He, Yanping Li, Xiaoguang Yang, Elena C Hemler, Yuehui Fang, Liyun Zhao, Jian Zhang, Zhenyu Yang, Zhu Wang, Li He, Jing Sun, Dong D Wang, Jingzhong Wang, Jianhua Piao, Xiaofeng Liang, Gangqiang Ding, Frank B HuSummaryBackgroundFew studies have used nationally representative data to describe dietary trends and the related cardiometabolic mortality burden in China. Thus, we aimed to characterise the trends in disease-related dietary factors as well as their associated disease burden among Chinese adults from 1982 to 2012....
Source: The Lancet Diabetes and Endocrinology - May 12, 2019 Category: Endocrinology Source Type: research
Osteoporosis and Sarcopenia Increase Frailty Syndrome in the Elderly
Conclusions
World population is aging and the increase in life expectancy is often unhealthy. In particular, musculoskeletal aging, which leads to sarcopenia and osteoporosis, has several causes such as changes in body composition, inflammation, and hormonal imbalance. Sarcopenia, osteoporosis, and more frequently, sarcopenic obesity are commonly associated with aging and frequently closely linked each other, often leading to the development of a frailty syndrome. Frailty syndrome favors an increased risk of loss function in daily activities, for cardiovascular diseases, cancers, falls, and mortality. As the number of eld...
Source: Frontiers in Endocrinology - April 23, 2019 Category: Endocrinology Source Type: research
Editorial: Telomeres and Epigenetics in Endocrinology
This study was hypothesis-driven; the genetic variants were selected for being previously and substantially genotyped. The big sample size and the rich panel of other biomarkers allowed the authors to conduct much more detailed analyses on this topic.
The third article by Provenzi et al. proposed their perspectives on the role of telomeres in premature birth and discussed the potential implications for early adversity and care in the neonatal intensive care unit (Pavanello et al.). Indeed, the speculation of telomeres in aging begins in the premature aging syndrome. It is thus interesting to examine if telomeres also play...
Source: Frontiers in Endocrinology - April 23, 2019 Category: Endocrinology Source Type: research
The Discovery and Development of Liraglutide and Semaglutide
We describe one such approach, albumin binding, and explain how it was applied in the development of the human GLP-1 analog liraglutide once daily and, subsequently, semaglutide once weekly. The pharmacology of these two long-acting GLP-1 analogs, in terms of improving glycemic control, reducing body weight and decreasing cardiovascular (CV) risk, is also reviewed, together with some novel biology. In addition, we describe the importance of accurate target (GLP-1 receptor) tissue expression analysis.
Now an established class of agents, GLP-1-based therapies represent a significant advance in the treatment of T2D. All curr...
Source: Frontiers in Endocrinology - April 11, 2019 Category: Endocrinology Source Type: research
Orexin-A Prevents Lipopolysaccharide-Induced Neuroinflammation at the Level of the Intestinal Barrier
We examined a possible protective effect of OX-A against LPS-induced ROS formation and microglia activation. To mimic in vitro the connection between gut and brain and to study the putative effect on the cortical microglia, we used a co-culture of Caco-2 cells and primary cortical microglia with Caco-2 cells placed at the apical side of a transwell and primary cortical microglia at the basolateral side. All treatments used to study the apical vs. basal connection were applied to the apical compartment. We used DHR (10 μM, 20 min), a cell-permeable fluorogenic probe useful for the detection of ROS formation, to dete...
Source: Frontiers in Endocrinology - April 9, 2019 Category: Endocrinology Source Type: research
Cardiovascular Programming During and After Diabetic Pregnancy: Role of Placental Dysfunction and IUGR
This study demonstrated that the incidence of ischemic heart disease and death were three times higher among men with low birth weight compared to men with high birth weight (5). Epidemiological investigations of adults born at the time of the Dutch famine between 1944 and 1945 revealed an association between maternal starvation and a low infant birth weight with a high incidence of hypertension and coronary heart disease in these adults (23). Furthermore, Painter et al. reported the incidence of early onset coronary heart disease among persons conceived during the Dutch famine (24). In that regard, Barker's findin...
Source: Frontiers in Endocrinology - April 8, 2019 Category: Endocrinology Source Type: research
Trans fatty acids and lipid profile: A serious risk factor to cardiovascular disease, cancer and diabetes
The objective of the review to demonstrate the causal association between trans fatty acid intake and increase the risk of coronary heart disease through their influence on lipoprotein, association with atherosclerosis, stroke, diabetes and cancer.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - March 17, 2019 Category: Endocrinology Source Type: research
Ideal cardiovascular health, glycaemic status and incident type 2 diabetes mellitus: the REasons for Geographic and Racial Differences in Stroke (REGARDS) study
Conclusions/interpretationA higher number of ideal CVH components was associated with a dose-dependent lower risk of diabetes for participants with normal fasting glucose but not IFG. Tailored efforts that take into account observed differences by race and glycaemic level are needed for the primordial prevention of diabetes.
Source: Diabetologia - January 15, 2019 Category: Endocrinology Source Type: research
Diet replacement plan lowers risk of heart disease, stroke and diabetes
A low calorie diet replacement plan can work to help tackle obesity, lower the risk of heart disease, stroke and diabetes, according to a study published inThe BMJ.Daily Mail
Source: Society for Endocrinology - September 28, 2018 Category: Endocrinology Source Type: news
