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Total 55 results found since Jan 2013.

Community-based Rehabilitation Training after stroke: protocol of a pilot randomised controlled trial (ReTrain)
Introduction The Rehabilitation Training (ReTrain) intervention aims to improve functional mobility, adherence to poststroke exercise guidelines and quality of life for people after stroke. A definitive randomised controlled trial (RCT) is required to assess the clinical and cost-effectiveness of ReTrain, which is based on Action for Rehabilitation from Neurological Injury (ARNI). The purpose of this pilot study is to assess the feasibility of such a definitive trial and inform its design. Methods and analysis A 2-group, assessor-blinded, randomised controlled external pilot trial with parallel mixed-methods process evalu...
Source: BMJ Open - October 2, 2016 Category: Journals (General) Authors: Dean, S. G., Poltawski, L., Forster, A., Taylor, R. S., Spencer, A., James, M., Allison, R., Stevens, S., Norris, M., Shepherd, A. I., Calitri, R. Tags: Open access, Health services research, Rehabilitation medicine, Sports and exercise medicine Protocol Source Type: research

Intervention to reduce sedentary behaviour and improve outcomes after stroke (Get Set Go): a study protocol for the process evaluation of a pilot cluster randomised controlled trial (RECREATE)
We report the protocol for the process evaluation which will address the following objectives: (1) describe and clarify causal assumptions about the intervention, and its mechanisms of impact; (2) assess implementation fidelity; (3) explore views, perceptions and acceptability of the intervention to staff, stroke survivors and their carers; (4) establish the contextual factors that influence implementation, intervention mechanisms and outcomes. Methods and analysis This pilot trial will be conducted in 15 UK-based National Health Service stroke services. This process evaluation study, underpinned by the Medical Research C...
Source: BMJ Open - September 12, 2023 Category: General Medicine Authors: Johansson, J. F., Shannon, R., Mossabir, R., Airlie, J., Ozer, S., Moreau, L. A., Farrin, A., Mead, G., English, C., Fitzsimons, C. F., Clarke, D. J., Forster, A., on behalf of the RECREATE Programme Management Group, RECREATE Programme Management Group, Tags: Open access, Rehabilitation medicine Source Type: research

Nigeria: Stroke Affects Seven Nigerians Every Hour - Expert
[Daily Trust]National clinical director for stroke, England National Health Service, Dr Tony Rudd has explained that cases of stroke is going to get worse if there is no coordinated policy to prevent it.
Source: AllAfrica News: Health and Medicine - December 19, 2014 Category: African Health Source Type: news

Length of hospital stay is shorter in South Asian patients with Ischaemic Stroke
Ischaemic stroke is a global healthcare issue and in the UK one percent of all admissions to National Health Service (NHS) hospitals were due to stroke [1]. It is the leading cause of disability, with more than half of the survivors left dependent on others, of which 11% are newly admitted to care homes. The majority of survivors will require rehabilitation and additional care in the community [2,3]. These additional needs culminate with longer hospital admissions, with a mean length of hospital stay (LOS) of 20days [3].
Source: International Journal of Cardiology - March 25, 2015 Category: Cardiology Authors: Rahul Potluri, Mohammed Wasim, Bharat Markandey, Arouna Kapour, Niece Khouw, Paul Carter, Hardeep Uppal, Suresh Chandran Tags: Letter to the editor Source Type: research

Cost-effectiveness of Apixaban Compared With Edoxaban for Stroke Prevention in Nonvalvular Atrial Fibrillation.
Abstract PURPOSE: The purpose of this analysis was to assess the cost-effectiveness of apixaban 5 mg BID versus high- and low-dose edoxaban (60 mg and 30 mg once daily) as intended starting dose strategies for stroke prevention in patients from a UK National Health Service perspective. METHODS: A previously developed and validated Markov model was adapted to evaluate the lifetime clinical and economic impact of apixaban 5 mg BID versus edoxaban (high and low dose) in patients with nonvalvular atrial fibrillation. A pairwise indirect treatment comparison was conducted for clinical end points, and price parity ...
Source: Clinical Therapeutics - October 15, 2015 Category: Drugs & Pharmacology Authors: Lip GY, Lanitis T, Kongnakorn T, Phatak H, Chalkiadaki C, Liu X, Kuznik A, Lawrence J, Dorian P Tags: Clin Ther Source Type: research

Cardiovascular and stroke disease risk among doctors: a cross-sectional study.
Abstract The leading causes of death in the world are cardiovascular disease (CVD) and stroke according to the World Health Organization, as is also the case in India. There is also a high prevalence of major conventional risk factors in India, where 18.3%, 9.0% and 14.1% of adults are diagnosed with hypertension, diabetes and smoking, respectively. The aim of the present study was to look at the risk of CVD among doctors in our country using a validated tool developed by the National Health Service (NHS) in the UK, the QRISK3 calculator. PMID: 32460685 [PubMed - as supplied by publisher]
Source: Tropical Doctor - May 27, 2020 Category: Tropical Medicine Authors: Pillay R, Rathish B, Philips GM, Kumar RA, Francis A Tags: Trop Doct Source Type: research

What is the Price of the Potential for a Meaningful Recovery following Intracerebral Hemorrhage?
In this issue of the Journal of Stroke and Cerebrovascular Diseases, Vardanyan and colleagues report on the cost-utility of minimally invasive surgery (MIS) with thrombolysis for spontaneous intracerebral hemorrhage (ICH) from the perspective of the United Kingdom (UK) National Health Service (NHS)1 using data from the Minimally Invasive Surgery Plus Alteplase in Intracerebral Hemorrhage Evacuation (MISTIE III) trial2 and the UK Sentinel Stroke National Audit Programme (SSNAP).3 The economic evaluation revealed that the incremental cost-effectiveness ratio for MIS with thrombolysis fell significantly above the UK's Nationa...
Source: Journal of Stroke and Cerebrovascular Diseases - July 27, 2021 Category: Neurology Authors: Lourdes R. Carhuapoma, Avni Kapadia, Henry A. Glick, Daniel F. Hanley Source Type: research

The Cost-Effectiveness Of Novel Oral Anticoagulants For The Prevention Of Stroke In Atrial Fibrillation In England And Wales
Determine the most cost-effective, licensed, first-line anticoagulant for the prevention of ischemic stroke in patients with non-valvular atrial fibrillation (AF) in England and Wales from the perspective of the UK National Health Service.
Source: Value in Health - October 23, 2015 Category: Global & Universal Authors: H Thom, W Hollingworth, PA Bryden, J Sterne, PN Bodalia, P Davies, JA Lopez-Lopez, GN Okoli, DM Caldwell, S Dias, D Eaton, J Higgins, C Salisbury, J Savovic, R Sofat, A Stephens-Boal, A Hingorani, NJ Welton Source Type: research

Patient, carer and public involvement in major system change in acute stroke services: The construction of value
DiscussionInvolvement was seen to have strategic and intrinsic value. Its strategic value lay in facilitating the implementation of a model of care that aimed to deliver evidence‐based care to all; its intrinsic value was in the idea of citizen participation in change processes as an end in its own right. The concept of value, rather than impact, may provide greater traction in analyses of contemporary involvement practices.
Source: Health Expectations - January 18, 2018 Category: Health Management Authors: Christopher McKevitt, Angus I.G. Ramsay, Catherine Perry, Simon J. Turner, Ruth Boaden, Charles D.A. Wolfe, Naomi J. Fulop Tags: ORIGINAL RESEARCH PAPER Source Type: research

Aspirin and Subarachnoid Haemorrhage in the UK Biobank
In this study, we aimed to clarify the association between aspirin and SAH in the general population. The UK Biobank is a prospective population-based cohort study. Sex, age, smoking, alcohol, medication use, hypertension, blood pressure, ischaemic heart disease and stroke were recorded at baseline assessments. Follow-up is conducted through linkages to National Health Service data including electronic, coded death certificate, hospital and primary care data. Cox proportional hazards modelling was used to analyse the association between aspirin use and SAH. Of the 501,060 participants included in the analysis, a total of 5...
Source: Translational Stroke Research - June 29, 2023 Category: Neurology Source Type: research

Heterogeneous effects of patient choice and hospital competition on mortality
Publication date: Available online 9 September 2018Source: Social Science & MedicineAuthor(s): Giuseppe Moscelli, Hugh Gravelle, Luigi Siciliani, Rita SantosAbstractWe examine whether the relaxation of constraints on patient choice of hospital in the English National Health Service in 2006 led to greater changes in mortality for hospitals which faced more rivals before the choice reform. We use patient level data from 2002 to 2010 for three high volume emergency conditions with high mortality risk: acute myocardial infarction (AMI) (288,279 patients), hip fracture (91,005 patients), stroke (214,103 patients). Since mortali...
Source: Social Science and Medicine - September 10, 2018 Category: Psychiatry & Psychology Source Type: research

Rivaroxaban for Preventing Atherothrombotic Events in People with Acute Coronary Syndrome and Elevated Cardiac Biomarkers: An Evidence Review Group Perspective of a NICE Single Technology Appraisal
Abstract As part of its Single Technology Appraisal process, the National Institute for Health and Care Excellence (NICE) invited the company that manufactures rivaroxaban (Xarelto, Bayer) to submit evidence of the clinical and cost effectiveness of rivaroxaban for the prevention of adverse outcomes in patients after the acute management of acute coronary syndrome (ACS). The School of Health and Related Research Technology Appraisal Group at the University of Sheffield was commissioned to act as the independent Evidence Review Group (ERG). The ERG produced a critical review of the evidence for the clinical and cos...
Source: PharmacoEconomics - December 21, 2015 Category: Health Management Source Type: research

Quality and the curate's egg
A famous cartoon in the satirical magazine Punch from the 1890s shows a meek curate assuring his dinner host that his egg is not spoiled. "Parts of it are exceptional", he suggests. We, the knowing reader, appreciate the humour. An egg cannot be good in parts. For those who think about quality, the question of whether care can be good in parts is a tricky one. That a hospital might deliver better care for one clinical service—top notch cardiac surgery, say, but below average stroke care—would not surprise anyone. But, the idea that quality itself, even within a given clinical domain, like cardiac surgery or str...
Source: Quality and Safety in Health Care - June 12, 2014 Category: Health Management Authors: Greaves, F., Jha, A. K. Tags: Editor's choice Editorials Source Type: research

A Novel Atrial Fibrillation Evaluation Modelling Solution For NHS
Approximately every fifth stroke in UK is due to AF and costs the UK National Health Service are between $12,000 and $17,500 per stroke. The aim of this study was to undertake a retrospective health economic analysis of the cost-effectiveness and implications related to opportunistic Atrial Fibrillation (AF) screening in primary care and the detection of previously undiagnosed AF cases in patients, and create a novel modelling solution that can empower individual users and organisations in England, Wales and Northern Ireland in their decision making, technology assessment, comparison of various anticoagulation d rug group...
Source: Value in Health - October 1, 2017 Category: International Medicine & Public Health Authors: G Xydopoulos, R Fordham, Z Khanbai Source Type: research

Content Analysis of Patient Safety Incident Reports for Older Adult Patient Transfers, Handovers, and Discharges: Do They Serve Organizations, Staff, or Patients?
Objective The aim of the study was to analyze content of incident reports during patient transitions in the context of care of older people, cardiology, orthopedics, and stroke. Methods A structured search strategy identified incident reports involving patient transitions (March 2014–August 2014, January 2015–June 2015) within 2 National Health Service Trusts (in upper and lower quartiles of incident reports/100 admissions) in care of older people, cardiology, orthopedics, and stroke. Content analysis identified the following: incident classifications; active failures; latent conditions; patient/relative inv...
Source: Journal of Patient Safety - December 1, 2021 Category: Health Management Tags: Original Studies Source Type: research