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Infectious Disease: Coronavirus

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Total 2126 results found since Jan 2013.

Implications of COVID-19 to Stroke Medicine: An Epidemiological and Pathophysiological Perspective
Curr Vasc Pharmacol. 2022;20(4):333-340. doi: 10.2174/1570161120666220428101337.ABSTRACTThe neurological complications of Coronavirus 2019 (COVID-19) including stroke have been documented in the recent literature. COVID-19-related inflammation is suggested to contribute to both a hypercoagulable state and haemorrhagic transformation, including in younger individuals. COVID-19 is associated with a heightened risk of ischaemic stroke. Haemorrhagic stroke in COVID-19 patients is associated with increased morbidity and mortality. Cerebral venous sinus thrombosis (CVST) accounts for <1% of stroke cases in the general populat...
Source: Current Vascular Pharmacology - November 3, 2022 Category: Drugs & Pharmacology Authors: Alan King Karen M Doyle Source Type: research

Stroke patterns and outcomes during the second wave of COVID-19 pandemic: a cross-sectional study
CONCLUSION: The factors that cause the delayed transfer to the hospital and onset of treatment should be addressed. Patient counseling about the likely prognosis can be done after evaluating the probable outcome based on the NIHSS score and median duration of hospital stay. Nevertheless, mechanisms should be developed to reduce the prehospital delay at the ground level as well as at the policy level.PMID:37363610 | PMC:PMC10289718 | DOI:10.1097/MS9.0000000000000722
Source: Annals of Medicine - June 26, 2023 Category: Internal Medicine Authors: Bikram P Gajurel Subarna Giri Parishma Tamrakar Anupama Pandeya Niraj Gautam Aashish Shrestha Ragesh Karn Reema Rajbhandari Rajeev Ojha Source Type: research

Interventional Stroke Care in the Era of COVID-19
The current coronavirus disease (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 has led to immense strain on healthcare systems and workers. Patients with severe symptoms of COVID-19 may also present with acute neurological emergencies such as ischemic stroke. Ischemic stroke in these patients may result from COVID-19 related complications or decompensation of previously asymptomatic cerebrovascular disorders, or concurrent ischemic stroke from common stroke risk factors in a patient with COVID-19. Acute ischemic stroke patients with large vessel occlusions require emergent triage, intensive c...
Source: Frontiers in Neurology - May 7, 2020 Category: Neurology Source Type: research

COVID-19: Stroke Admissions, Emergency Department Visits, and Prevention Clinic Referrals.
Abstract We assessed the impact of the coronavirus disease 19 (COVID-19) pandemic on code stroke activations in the ED, stroke unit admissions, and referrals to the stroke prevention clinic at London's regional stroke center, serving a population of 1.8 million in Ontario, Canada. We found a 20% drop in the number of code strokes in 2020 compared to 2019, immediately after the first cases of COVID-19 were officially confirmed. There were no changes in the number of stroke admissions and there was a 22% decrease in the number of clinic referrals, only after the provincial lockdown. Our findings suggest that the dec...
Source: The Canadian Journal of Neurological Sciences - May 25, 2020 Category: Neurology Authors: Bres Bullrich M, Fridman S, Mandzia JL, Mai LM, Khaw A, Vargas Gonzalez JC, Bagur R, Sposato LA Tags: Can J Neurol Sci Source Type: research

COVID-19 and \ stroke: Incidental, triggered or causative
Rohit Bhatia, M V. Padma SrivastavaAnnals of Indian Academy of Neurology 2020 23(3):318-324 Stroke is a serious neurological complication observed during the ongoing COVID-19 (coronavirus associated disease 2019) pandemic caused by SARS-CoV-2 (severe acute respiratory syndrome, corona virus 2) and includes both ischemic stroke and intracerebral haemorrhage. We reviewed factors that could potentially contribute to the occurrence of stroke among patients with COVID-19. There could be an interaction between the conventional risk factors of stroke, infection, systemic inflammatory response and plaque destabilisation. Inflamma...
Source: Annals of Indian Academy of Neurology - June 9, 2020 Category: Neurology Authors: Rohit Bhatia M V. Padma Srivastava Source Type: research

Impact of the COVID-19 pandemic on hyperacute stroke treatment: experience from a comprehensive stroke centre in Singapore
AbstractThe Coronavirus disease 2019 (COVID-19) pandemic is rapidly evolving and affecting healthcare systems across the world. Singapore has escalated its alert level to Disease Outbreak Response System Condition (DORSCON) Orange, signifying severe disease with community spread. We aimed to study the overall volume of AIS cases and the delivery of hyperacute stroke services during DORSCON Orange. This was a single-centre, observational cohort study performed at a comprehensive stroke centre responsible for AIS cases in the western region of Singapore, as well as providing care for COVID-19 patients. All AIS patients revie...
Source: Journal of Thrombosis and Thrombolysis - July 12, 2020 Category: Hematology Source Type: research

Where have our patients gone? The impact of COVID ‐19 on stroke imaging and intervention at an Australian stroke centre
ConclusionsThe significant decrease in volume of ‘code stroke’ activations and acute stroke imaging following lockdown was accompanied by a concomitant decrease in patients with LVOs and ECRs. The decrease in imaging was therefore not driven purely by patients with mild strokes and stroke mimics, but also included those with severe strokes. Si nce Australia had a low prevalence of COVID‐19, this observed decrease cannot be attributed to hospital congestion and is instead likely driven by patient fear.
Source: Journal of Medical Imaging and Radiation Oncology - August 19, 2020 Category: Radiology Authors: Shalini A Amukotuwa, Roland Bammer, Julian Maingard Tags: Medical Imaging —Original Article Source Type: research

Impact of COVID-19 Pandemic on a Regional Stroke Thrombectomy Service in the United Kingdom
Conclusion: The COVID-19 pandemic has had a negative impact on the stroke admission numbers but not stroke thrombectomy rate, successful recanalization rate, or early neurological outcome. Internal delays actually improved during the COVID-19 pandemic. Further studies should examine the effects of the COVID-19 pandemic on longer term outcome.Cerebrovasc Dis
Source: Cerebrovascular Diseases - December 11, 2020 Category: Neurology Source Type: research

COVID-19 Stroke Apical Lung Examination Study: A Diagnostic and Prognostic Imaging Biomarker in Suspected Acute Stroke EXTRACRANIAL VASCULAR
CONCLUSIONS: We identified a simple, reliable, and accurate COVID-19 diagnostic and prognostic imaging biomarker obtained from CTA lung apices: the presence or absence of ground-glass opacification. Our findings have important implications in the management of patients presenting with suspected stroke through early identification of COVID-19 and the subsequent limitation of disease transmission.
Source: American Journal of Neuroradiology - January 11, 2021 Category: Radiology Authors: Siddiqui, J., Bala, F., Sciacca, S., Falzon, A. M., Benger, M., Matloob, S. A., Miller, F. N. A. C., Simister, R. J., Chatterjee, I., Sztriha, L. K., Davagnanam, I., Booth, T. C. Tags: EXTRACRANIAL VASCULAR Source Type: research

Pathomechanism and Management of Stroke in COVID-19: Review of Immunopathogenesis, Coagulopathy, Endothelial Dysfunction, and Downregulation of ACE2
J Clin Neurol. 2021 Apr;17(2):155-163. doi: 10.3988/jcn.2021.17.2.155.ABSTRACTCoronavirus disease 2019 (COVID-19) can reportedly manifest as an acute stroke, with most cases presenting as large vessel ischemic stroke in patients with or without comorbidities. The exact pathomechanism of stroke in COVID-19 remains ambiguous. The findings of previous studies indicate that the most likely underlying mechanisms are cerebrovascular pathological conditions following viral infection, inflammation-induced endothelial dysfunction, and hypercoagulability. Acute endothelial damage due to inflammation triggers a coagulation cascade, t...
Source: Journal of Clinical Neurology - April 9, 2021 Category: Neurology Authors: Putu Lohita Rahmawati Kumara Tini Ni Made Susilawathi I A Sri Wijayanti Dpg Purwa Samatra Source Type: research