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Procedure: Lumbar Puncture

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Total 48 results found since Jan 2013.

Immunoluminometric assay for copeptin measurement in cerebrospinal fluid: Technical aspects and pilot study
ConclusionsThis assay provides to best of our knowledge for the first time initial ranges values of CSF copeptin for patients without acute neurological disease and in patients with aSAH. Thus, it opens new doors to develop further calculations and relationships between diseases biomarker and outcome prediction.
Source: Clinica Chimica Acta - September 16, 2018 Category: Laboratory Medicine Source Type: research

Immunoluminometric assay for copeptin measurement in cerebrospinal fluid: Technical aspects and pilot study.
CONCLUSIONS: This assay provides to best of our knowledge for the first time initial ranges values of CSF copeptin for patients without acute neurological disease and in patients with aSAH. Thus, it opens new doors to develop further calculations and relationships between diseases biomarker and outcome prediction. PMID: 30194934 [PubMed - as supplied by publisher]
Source: International Journal of Clinical Chemistry - September 5, 2018 Category: Chemistry Authors: Mindt S, Andrade-Barazarte H, Tokhi U, Ludtka C, Neumaier M, Hänggi D Tags: Clin Chim Acta Source Type: research

Brain metabolic correlates of CSF Tau protein in a large cohort of Alzheimer's disease patients: a CSF and FDG PET study.
CONCLUSIONS: t-Tau deposition in brain is related to temporal, parietal and frontal hypometabolism in AD. PMID: 29066367 [PubMed - as supplied by publisher]
Source: Brain Research - October 21, 2017 Category: Neurology Authors: Chiaravalloti A, Barbagallo G, Ricci M, Martorana A, Ursini F, Sannino P, Karalis G, Schillaci O Tags: Brain Res Source Type: research

A Diagnostic Approach to Stroke in Young Adults
Opinion statementOptimal diagnosis and management of stroke in young adults benefit from a multidisciplinary team, including a vascular neurology specialist. In addition to the “standard” vascular risk factors including smoking, hypertension, diabetes, and hyperlipidemia, one needs to consider alternative etiologies including substance abuse, carotid/vertebral artery dissections, and rare genetic conditions among others. Once a young patient is determined to have had a stroke, the next question a clinician should ask iswhy did this patient have a stroke? A “heart to head” diagnostic approach is recommended. A thoro...
Source: Current Treatment Options in Cardiovascular Medicine - September 25, 2017 Category: Cardiology Source Type: research

Correlation of CSF flow using phase-contrast MRI with ventriculomegaly and CSF opening pressure in mucopolysaccharidoses
ConclusionsIn MPS patients ventriculomegaly is associated with a severe phenotype, increased cognitive decline, WM lesion severity and enlarged PVS. The authors have shown that there are associations between CSF flow measurements and measurements related to CSF volumetrics. There was also an association of volumetric measurements with the degree of dilated PVS.
Source: Fluids and Barriers of the CNS - September 18, 2017 Category: Neuroscience Source Type: research

European Stroke Organization guideline for the diagnosis and treatment of cerebral venous thrombosis – endorsed by the European Academy of Neurology
ConclusionsMulticentre observational and experimental studies are needed to increase the level of evidence supporting recommendations on the diagnosis and management of CVT.
Source: European Journal of Neurology - August 20, 2017 Category: Neurology Authors: J. M. Ferro, M. ‐G. Bousser, P. Canhão, J. M. Coutinho, I. Crassard, F. Dentali, M. Minno, A. Maino, I. Martinelli, F. Masuhr, D. Aguiar de Sousa, J. Stam, Tags: Guidelines Source Type: research

Association of Cerebral Venous Thrombosis and Intracranial Hypotension: Review of 3 Cases
We describe 3 cases in which this phenomenon occurred, as a result of a lumbar puncture or due to a spontaneous cerebrospinal fluid leak. We emphasize the importance of early detection of the intracranial hypotension syndrome, the most common clinical manifestation being orthostatic headache. It is not an innocent condition as it is associated with other potential complications such as subdural hygroma/hematoma, cranial nerve palsies, cerebellar tonsillar descent, and even brainstem manifestations.
Source: Journal of Stroke and Cerebrovascular Diseases - June 13, 2017 Category: Neurology Authors: Leen Sinnaeve, Ludo Vanopdenbosch, Koen Paemeleire Tags: Case Studies Source Type: research

A Case of Hypertensive Encephalopathy with Enlarged Optic Nerve Sheath Measured by Transorbital Sonography
This case report describes our experience in using transorbital sonography to evaluate pathological changes in the central nervous system in hypertensive encephalopathy. A 49-year-old man with nausea, headache, and mild confusion was diagnosed with hypertensive encephalopathy by brain magnetic resonance imaging (MRI), which revealed vasogenic edema in the bilateral thalamus and the brain stem. Lumbar puncture showed no severe intracranial hypertension. Transorbital sonography showed an increase in the optic nerve sheath diameter (ONSD).
Source: Journal of Stroke and Cerebrovascular Diseases - November 8, 2016 Category: Neurology Authors: Takaya Kitano, Tomohisa Nezu, Tomoya Mukai, Jyunichi Uemura, Yuko Wada, Yoshiki Yagita Tags: Case Studies Source Type: research

Treatment With Prothrombin Complex Concentrate to Enable Emergency Lumbar Puncture in Patients Receiving Vitamin K Antagonists
Conclusion Reversing the effect of vitamin K antagonist with prothrombin complex concentrates to enable emergency lumbar puncture appears effective and safe, particularly in regard to bleeding events.
Source: Annals of Emergency Medicine - April 14, 2016 Category: Emergency Medicine Source Type: research

An Uncommon Cause for Multiple Cerebral Ischemic Infarcts (P4.344)
Conclusions: Cerebral infarcts due to CM in immunocompetent patients are unusual. However, cryptococcal infection should be considered in atypical stroke manifestations, since early diagnosis and prompt treatment can improve outcome.Disclosure: Dr. Khattak has nothing to disclose. Dr. Desai has nothing to disclose. Dr. Desai has nothing to disclose. Dr. Wise has nothing to disclose. Dr. Moore has nothing to disclose. Dr. Shah has nothing to disclose. Dr. Wilder has nothing to disclose. Dr. Remmel has nothing to disclose. Dr. Liu has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Khattak, J., Desai, M., Desai, D., Wise, E., Moore, K., Shah, J., Wilder, M., Remmel, K., Liu, W. Tags: Cerebrovascular Case Reports Source Type: research

Unique CT Perfusion Imaging in a Case of HaNDL: New Insight into Pathophysiology of Acute Attacks (P4.114)
Conclusions: The pattern of global left hemispheric hypoperfusion seen in this case supports previous hypotheses of secondary oligemia induced by a hemispheric wave of cortical spreading depression (CSD). However, the right ACA territory hypoperfusion represents a phenomenon never previously reported in this field. We speculate that the secondary vasomotor changes induced by CSD in the left hemisphere, spread to the right hemisphere via the anomalous vascular supply. Such a mechanism of direct vascular propagation through vessel gap junctions has been described in animal studies. This unique case provides a valuable contri...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Burke, M., Lamb, M., Hohol, M., Lay, C. Tags: Headache: Imaging and Other Source Type: research

Sensitivity of Early Brain Computed Tomography to Exclude Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Meta-Analysis Clinical Sciences
Conclusions— In patients presenting with thunderclap headache and normal neurological examination, normal brain CT within 6 hours of headache is extremely sensitive in ruling out aneurysmal SAH.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Dubosh, N. M., Bellolio, M. F., Rabinstein, A. A., Edlow, J. A. Tags: Computerized Tomography (CT), Cerebral Aneurysm, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Clinical Sciences Source Type: research

Perceived Appropriateness of Shared Decision‐Making in the Emergency Department: A Survey Study
ConclusionsAcceptance of SDM among emergency physicians appears to be strong across management categories (diagnostic testing, treatment, and disposition) and in a variety of clinical scenarios. SDM is perceived by most EPs to be medicolegally protective.This article is protected by copyright. All rights reserved.
Source: Academic Emergency Medicine - January 25, 2016 Category: Emergency Medicine Authors: Marc A. Probst, Hemal K. Kanzaria, Dominick L. Frosch, Erik P. Hess, Gary Winkel, Ka Ming Ngai, Lynne D. Richardson Tags: Original Contribution Source Type: research

Perceived Appropriateness of Shared Decision-Making in the Emergency Department: A Survey Study.
CONCLUSIONS: Acceptance of SDM among emergency physicians appears to be strong across management categories (diagnostic testing, treatment, and disposition) and in a variety of clinical scenarios. SDM is perceived by most EPs to be medicolegally protective. This article is protected by copyright. All rights reserved. PMID: 26806170 [PubMed - as supplied by publisher]
Source: Accident and Emergency Nursing - January 25, 2016 Category: Emergency Medicine Authors: Probst MA, Kanzaria HK, Frosch DL, Hess EP, Winkel G, Ngai KM, Richardson LD Tags: Acad Emerg Med Source Type: research

Serum TRSUT Titer ≥1: 16 Is a Predictor for Neurosyphilis Among HIV-Infected Patients With Concurrent Syphilis and No Neurological Symptoms
Abstract: Investigating the predictors for lumbar puncture to diagnose the asymptomatic neurosyphilis among HIV and syphilis co-infected patients in Shanghai, China. Respectively, screening the medical records from August 1, 2009 to June 30, 2015. Those HIV-infected patients with concurrent syphilis who had received lumbar puncture were selected and their clinical and demographic data were recorded. Participants comprised symptomatic and asymptomatic patients. The latter ones could be further divided into 3 groups: late syphilis, early syphilis with anti-syphilis treatment failure, and early syphilis with serum toludine re...
Source: Medicine - November 1, 2015 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research