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Evaluating the Dissemination and Implementation Impact of a Rehabilitation Intervention: The Graded Repetitive Arm Supplementary Program (GRASP)
CONCLUSION: The Payback Framework is useful to evaluate the dissemination and implementation impacts of a rehabilitation intervention. GRASP has been implemented extensively in clinical practice and community in a relatively short time since it has been developed.PMID:37736384 | PMC:PMC10510554 | DOI:10.3138/ptc-2022-0117
Source: Physiotherapy Canada - September 22, 2023 Category: Physiotherapy Authors: Chieh-Ling Yang Louise A Connell Janice J Eng Source Type: research

Physical strength levels and short-term memory efficiency in primary school children: a possible match?
CONCLUSIONS: These findings suggest that physical strength can positively influence short-term memory. In addition, this impact is enhanced in older-age children. Thus, primary school programs should stimulate physical strength to help children develop cognitive abilities.PMID:37736663 | DOI:10.23736/S0022-4707.23.14996-6
Source: Journal of Sports Medicine and Physical Fitness - September 22, 2023 Category: Sports Medicine Authors: Samuel Agostino Michela Calandretti Franco Veglio Federico Abate Daga Source Type: research

Artificial Intelligence for Drug Discovery: Are We There Yet?
Annu Rev Pharmacol Toxicol. 2023 Sep 22. doi: 10.1146/annurev-pharmtox-040323-040828. Online ahead of print.ABSTRACTDrug discovery is adapting to novel technologies such as data science, informatics, and artificial intelligence (AI) to accelerate effective treatment development while reducing costs and animal experiments. AI is transforming drug discovery, as indicated by increasing interest from investors, industrial and academic scientists, and legislators. Successful drug discovery requires optimizing properties related to pharmacodynamics, pharmacokinetics, and clinical outcomes. This review discusses the use of AI in ...
Source: Annual Review of Pharmacology and Toxicology - September 22, 2023 Category: Drugs & Pharmacology Authors: Catrin Hasselgren Tudor I Oprea Source Type: research

Clinical trials in Charcot-Marie-Tooth disorders: a retrospective and preclinical assessment
ConclusionCurrent CMT trials are exploring procedural and molecular therapeutic options with substantial participation of the pharmaceutical industry worldwide. Emerging drug therapies directed at molecular pathogenesis are being advanced in human clinical trials; however, the majority remain within animal investigations.
Source: Frontiers in Neurology - September 22, 2023 Category: Neurology Source Type: research

“It saved me from the emergency department”: A qualitative study of patient experience of virtual urgent care in Ontario
ConclusionVirtual care options are valued by patients and families; however, the nature of care needed by those accessing VUC and who can best provide that care needs to be evaluated to position it for sustainability. Understanding how virtual care performs from both a provider and patient perspective during the current crisis has implications for designing alternative care options beyond the COVID-19 pandemic.
Source: PLoS One - September 22, 2023 Category: Biomedical Science Authors: Katie N. Dainty Source Type: research

A complement to the H-index: a metric based on primary authorship
In an era of ever-increasing medical and scientific publications, metrics capturing research output are increasingly relevant. Currently, the leading measure for quantifying a researcher's publication record impact is the h-index. As proposed by Hirsch in 2005 it is a simple metric providing a number which is equal to the greatest number of publications by an author with each publication having a minimum of that same number of citations1. The h-index has continued to become more and more relevant for a researcher in terms of securing funding, vying for promotions, or applying for an academic position.
Source: The American Journal of Medicine - September 22, 2023 Category: General Medicine Authors: Pushan Dasgupta, Heinrich Taegtmeyer Tags: Commentary Source Type: research

The Additional Effect of Training Above the Maximal Metabolic Steady State on VO2peak, Wpeak and Time-Trial Performance in Endurance-Trained Athletes: A Systematic Review, Meta-analysis, and Reality Check
ConclusionA single training meso-cycle that includes training above MMSS can improveVO2peak in endurance-trained athletes more than training only below MMSS. However, we do not have sufficient evidence to conclude that concurrent adaptation occurs forWpeak or TT performance.
Source: Sports Medicine - September 22, 2023 Category: Sports Medicine Source Type: research

Professional virtue of civility and the responsibilities of medical educators and academic leaders
Incivility among physicians, between physicians and learners, and between physicians and nurses or other healthcare professionals has become commonplace. If allowed to continue unchecked by academic leaders and medical educators, incivility can cause personal psychological injury and seriously damage organisational culture. As such, incivility is a potent threat to professionalism. This paper uniquely draws on the history of professional ethics in medicine to provide a historically based, philosophical account of the professional virtue of civility. We use a two-step method of ethical reasoning, namely ethical analysis inf...
Source: Journal of Medical Ethics - September 22, 2023 Category: Medical Ethics Authors: McCullough, L. B., Coverdale, J., Chervenak, F. A. Tags: Open access Feature article Source Type: research

Pediatric ED Visits for Mental, Behavioral Conditions Increased During School Term
THURSDAY, Sept. 21, 2023 -- For children and adolescents, the number and proportion of weekly emergency department visits for mental health and behavioral conditions is higher during the academic year, according to research published in the Sept. 22...
Source: Drugs.com - Pharma News - September 21, 2023 Category: Pharmaceuticals Source Type: news

With Demand for Mental-Health Care Soaring on Campus, Faculty and Students Are Stepping Up to Help
After the pandemic shut down Duke University’s campus in 2020, public-policy professor Nick Carnes worried about how his students would fare both educationally and emotionally. Wanting to help in whatever way he could, he added a simple message to his email signature. “A note to students,” he wrote. “Please let me or another Duke professor know if you’re having any problems with your safety, well-being, or access to educational or other resources, or if you need to talk about anything right now, and/or if you know of another student who is having trouble. When in doubt, please reach out.&rd...
Source: TIME: Health - September 21, 2023 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthscienceclimate Source Type: news

Are Social Deprivation and Low Traditional Health Literacy Associated With Higher PROMIS CAT Completion in Orthopaedic Surgery?
CONCLUSION: Within an urban, socioeconomically diverse, orthopaedic patient population, health literacy was associated with PROMIS CAT questionnaire completion. Lower health literacy levels increased the likelihood of not completing any part of the assigned PROMIS CAT questionnaires. Additionally, patients completed PROMIS CAT without fully understanding the questions. This indicates that patient completion does not guarantee comprehension of the questions nor validity of their scores, even more so among patients with low health literacy. This is a substantive concern for fidelity of data gathered from PROMIS CAT.CLINICAL ...
Source: Clinical Orthopaedics and Related Research - September 21, 2023 Category: Orthopaedics Authors: Audrey L Litvak Nicholas A Lin Kelly K Hynes Jason A Strelzow Megan A Conti Mica Jeffrey G Stepan Source Type: research

Existing Nongated CT Coronary Calcium Predicts Operative Risk in Patients Undergoing Noncardiac Surgeries (ENCORES)
CONCLUSIONS: Prevalence and severity of coronary calcium obtained from existing nongated chest CT imaging improve preoperative clinical risk stratification before nongated surgery.PMID:37732454 | DOI:10.1161/CIRCULATIONAHA.123.064398
Source: Circulation - September 21, 2023 Category: Cardiology Authors: Daniel Y Choi Dena Hayes Samuel D Maidman Nehal Dhaduk Jill E Jacobs Anna Shmukler Jeffrey S Berger Germaine Cuff David Rehe Mitchell Lee Robert Donnino Nathaniel R Smilowitz Source Type: research

Involving patients and the public in nursing PhD projects: practical guidance, potential benefits and points to consider
CONCLUSION: Patients and the public should be involved in nursing PhD projects. Not only does this improve the quality of the research and raise the profile of nursing research, but it provides the opportunity for students to learn skills that they can develop further throughout their academic careers.IMPLICATIONS FOR PRACTICE: Obtaining high-quality patient and public involvement is an important skill for nurse researchers. The first steps in acquiring this skill should be taken during research training.PMID:37731298 | DOI:10.7748/nr.2023.e1891
Source: Nurse Researcher - September 21, 2023 Category: Nursing Authors: Chris McParland Bridget Johnston Bahaa Alassoud Maria Drummond Annabel Farnood Chandra Isabella Hostanida Purba Muzeyyen Seckin Saengrawee Thanthong Source Type: research

Athletic Trainers' Observations of Social Determinants of Health in the Collegiate Setting: A Card Study
CONCLUSIONS: Because ATs are positioned to accurately assess SDH, they can promote better patient-centered care and improve patient outcomes. Our results suggested many SDH observed by ATs in the college/university setting had a negative influence on patient health. Better support for patients with behavioral health issues and academic stressors is important because these SDH were commonly perceived to negatively influence health and well-being.PMID:37734734 | DOI:10.4085/1062-6050-0327.23
Source: J Athl Train - September 21, 2023 Category: Sports Medicine Authors: Kelsey J Picha Cailee E Welch Bacon Cassidy Evans Windsor Joy Lewis Alison R Snyder Valier Source Type: research

Remote Monitoring Compared With In-Office Surveillance of Blood Pressure in Patients With Pregnancy-Related Hypertension: A Randomized Controlled Trial
CONCLUSION: Remote monitoring can increase postpartum blood pressure ascertainment within 10 days of discharge for women with hypertensive disorders of pregnancy and has the potential to promote health equity.CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, NCT04823949.PMID:37734091 | DOI:10.1097/AOG.0000000000005327
Source: Obstetrics and Gynecology - September 21, 2023 Category: OBGYN Authors: Brittany J Arkerson Matthew M Finneran Solita R Harris Jessica Schnorr Eliza R McElwee Lauren Demosthenes Renata Sawyer Source Type: research