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Total 154 results found since Jan 2013.
CCR5- Δ32 polymorphism: a possible protective factor for post-stroke depressive symptoms
CONCLUSION: Carriers of the CCR5-Δ32 allele had a lower tendency to develop depressive symptoms post-stroke, and this phenomenon was more prominent in women. These findings could have clinical implications; they suggest a mechanism-based treatment target for post-stroke depression. Drugs mimicking this loss-of-function mutation exist and could serve as a novel antidepressant therapy.PMID:34291627 | DOI:10.1503/jpn.200197
Source: Journal of Psychiatry and Neuroscience - July 22, 2021 Category: Psychiatry Authors: Oren Tene Hen Hallevi Jeremy Molad Saly Usher Estelle Seyman Natan M Bornstein Shani Shenhar-Tsarfaty Einor Ben Assayag Source Type: research
Depressive symptoms following stroke and transient ischemic attack: is it time for a more intensive treatment approach? results from the TABASCO cohort study.
CONCLUSIONS: Our results support depression screening among stroke and TIA survivors as a tool to identify patients who are prone to have a worse cognitive and functional outcome. These patients may benefit from closer medical surveillance and a more intensive treatment approach.
TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT01926691.
PMID: 27035632 [PubMed - as supplied by publisher]
Source: Journal of Clinical Psychiatry - April 3, 2016 Category: Psychiatry Tags: J Clin Psychiatry Source Type: research
Delayed-onset dementia after stroke or transient ischemic attack.
DISCUSSION: Severe SVD contributes importantly to delayed-onset dementia after stroke and/or TIA. Future clinical trials aiming to prevent delayed-onset dementia after stroke and/or TIA should target this high-risk group.
PMID: 27327542 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - June 23, 2016 Category: Psychiatry Tags: Alzheimers Dement Source Type: research
Cognitive Reserve Attenuates 6-Year Decline in Executive Functioning after Stroke.
CONCLUSION: The detrimental aftereffects of stroke on subsequent decline in executive functioning may be attenuated in individuals who have accumulated greater cognitive reserve through leisure activity engagement across their life.
PMID: 32209793 [PubMed - as supplied by publisher]
Source: Dementia and Geriatric Cognitive Disorders - March 28, 2020 Category: Psychiatry Tags: Dement Geriatr Cogn Disord Source Type: research
Cognitive screening in patients with stroke: a cross-sectional study
Conclusion The results showed that through positive screening for cognitive impairment cutoffs associated with neurological impairment were found, need to be adjusted for age and education, suggesting that these associations are preferably taken into consideration in planning the neuropsychological rehabilitation of stroke patients.
Source: Jornal Brasileiro de Psiquiatria - August 9, 2014 Category: Psychiatry Source Type: research
Depression Symptoms in Chronic Left Hemisphere Stroke Are Related to Dorsolateral Prefrontal Cortex Damage.
This study examines relationships between depression symptoms and psychosocial factors and then uses multivariate lesion-symptom mapping to localize depression symptoms in people with chronic left hemisphere stroke. Depression symptoms relate inversely to education and directly to physical disability. Damage in the left dorsolateral prefrontal cortex is associated with greater depression symptoms. These results demonstrate a neurological contribution to depression symptoms in chronic left hemisphere stroke and provide evidence of convergent biological mechanisms for poststroke depression symptoms and major depression with ...
Source: Journal of Neuropsychiatry and Clinical Neurosciences - June 5, 2016 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research
Insomnia as an additional clinical correlate of suicidal ideation after stroke
Suicide-related behaviors are frequent among stroke survivors [1]. In a recent systematic review and meta-analysis [2], it has been shown that about one out of eight subjects suffering from stroke may have suicidal ideation afterward (i.e., thinking about, considering or planning suicide). Findings, based on 15 studies including 13 independent samples and 10,400 unique subjects, showed a pooled proportion of suicidal ideation of 11.8% (7.4% to 16.2%). Suicidal ideation was less likely in stroke survivors who were married, employed and had higher education levels.
Source: General Hospital Psychiatry - June 19, 2017 Category: Psychiatry Authors: Francesco Bartoli, Massimo Clerici, Cristina Crocamo, Giuseppe Carr à Tags: Letter to the Editor Source Type: research
Shared risk and protective factors between Alzheimer's disease and ischemic stroke: A population-based longitudinal study.
DISCUSSION: AD and IS share risk/protective profiles, and SPFs seem to counteract the adverse effects of SRFs on both AD and IS.
PMID: 33527694 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - February 3, 2021 Category: Psychiatry Tags: Alzheimers Dement Source Type: research
Relationships between care burden, resilience, and depressive symptoms among the main family caregivers of stroke patients: A cross-sectional study
ConclusionsResilience plays a mediating role in the correlation between care burden and depressive symptoms.ImpactThe findings indicated a protective effect of resilience in alleviating the negative influences of care burden on depressive symptoms, suggesting that resilience-training intervention may be developed to mitigate depressive symptoms of the main family caregivers of stroke patients.
Source: Frontiers in Psychiatry - September 20, 2022 Category: Psychiatry Source Type: research
Stimulants May Pose Short-Term Cardiovascular Risks in Older Adults
Older adults prescribed stimulant medications appear to be at an elevated risk of cardiovascular problems in the first 30 days after beginning the treatment, according to astudy published today inJAMA Network Open. However, these risks decrease over time, with no evidence of increased cardiovascular risk at six months and one year after initiating treatment.“Although stimulants are most commonly used among children and youth for the treatment of attention-deficit/hyperactivity disorder (ADHD), an increase in stimulant use among older adults in recent years has been observed,” wrote Mina Tadrous, PharmD., Ph.D., of the ...
Source: Psychiatr News - October 25, 2021 Category: Psychiatry Tags: cardiovascular problems heart attack JAMA Network Open off-label use older adults stimulants stroke transient ischemic attack ventricular arrhythmia Source Type: research
Assessing Depression and its Correlates Among Post-stroke Survivors with Aphasia in Sri Lanka
This study attempted to identify the individuals with depression among people with aphasia, to understand the influence of socio-demographic factors on depression, and to understand the relationship PSD has with language impairment and physical disability. We conducted a cross-sectional study with 78 participants recruited from three hospital-based speech and language therapy clinics in Sri Lanka. Sinhala Language Aphasia Assessment, Peradeniya Depression Scale, and Barthel Index were used to measure language skills, depression symptoms, and physical disability. From the sample, 25.6% (n = 20) were having depression. ...
Source: Journal of Psychosocial Rehabilitation and Mental Health - June 7, 2023 Category: Psychiatry Source Type: research
Leukocyte Telomere Length Is Related to Brain Parenchymal Fraction and Attention/Speed in the Elderly: Results of the Austrian Stroke Prevention Study
There are controversial results if leukocyte telomere length (LTL) is related to structural brain changes and cognitive decline in aging. Here, we investigated the association between LTL and 1) global MRI correlates of brain aging such as brain parenchymal fraction (BPF) and white matter hyperintensities (WMH) load and Fazekas score as well as 2) global (g-factor) and domain-specific cognition such as attention/speed, conceptualization, memory, and visuopractical skills. In total, 909 participants of the Austrian Stroke Prevention Study with LTL, MRI, and cognitive tests were included. There were 388 (42.7%) men, and the ...
Source: Frontiers in Psychiatry - February 27, 2020 Category: Psychiatry Source Type: research
Depressive Symptoms Are Associated with Reduced Cardiac Function Among Hispanics: Results from the PREVENCION Study
ConclusionsIn the PREVENCION sample tested, depressive symptoms were independently associated with cardiac function among Hispanic adults, even above and beyond pertinent factors such as demographic factors, cardiovascular risk factors, and comorbidities. Future studies should determine whether depressive symptoms are prospectively associated with systolic dysfunction, and examine the bio-behavioral pathways of this association.
Source: International Journal of Behavioral Medicine - November 10, 2020 Category: Psychiatry Source Type: research
