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Total 25 results found since Jan 2013.

Shengui Sansheng San Ameliorates Cerebral Energy Deficiency via Citrate Cycle After Ischemic Stroke
Conclusion In summary, SSS extraction significantly ameliorates cerebral energy metabolism via boosting citrate cycle, which mainly embodies the enhancements of blood glucose concentration, glucose and lactate transportation and glucose utilization, as well as the regulations of relative enzymes activities in citrate cycle. These ameliorations ultimately resulted in numerous ATP yield after stroke, which improved neurological function and infarcted volume. Collectively, it suggests that SSS extraction has exerted advantageous effect in the treatment of cerebral ischemia. Ethics Statement All animal operations were accor...
Source: Frontiers in Pharmacology - April 22, 2019 Category: Drugs & Pharmacology Source Type: research

A Network Pharmacology Approach for Exploring the Mechanisms of < em > Panax notoginseng < /em > Saponins in Ischaemic Stroke
CONCLUSIONS: The ameliorative effects of PNS against IS were predicted to be associated with the regulation of the IGF1-PI3K-Akt signalling pathway. Ginsenoside Re and ginsenoside Rb1 may play an important role in the treatment of IS.PMID:34434246 | PMC:PMC8382556 | DOI:10.1155/2021/5582782
Source: Evidence-based Complementary and Alternative Medicine - August 26, 2021 Category: Complementary Medicine Authors: Cong Wang Hao Chen Shi-Tang Ma Bin-Bin Mao Yu Chen Hao-Nan Xu Hao Yu Source Type: research

Janssen Highlights Continued Commitment to Cardiovascular & Metabolic Healthcare Solutions with Late-Breaking Data at the First Fully Virtual American College of Cardiology Scientific Session
RARITAN, N.J., March 20, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that it will unveil late-breaking data from its leading cardiovascular and metabolism portfolio during the virtual American College of Cardiology’s 69th Annual Scientific Session together with the World Congress of Cardiology (ACC.20/WCC) on March 28-30, 2020. Notably, four late-breaking abstracts for XARELTO® (rivaroxaban) will be presented, including data from the Phase 3 VOYAGER PAD study in patients with symptomatic peripheral artery disease (PAD) after lower-extremity revascularization.Click to Tweet: Jan...
Source: Johnson and Johnson - March 20, 2020 Category: Pharmaceuticals Source Type: news

8 Reasons You Get Dizzy
SPECIAL FROM Grandparents.com Who hasn’t gotten up quickly from sitting down and felt a little bit dizzy? Or had a stomach virus and things spun a bit? But while dizziness can be a side effect of minor health issues, it can also be a sign of a serious health problem. “Dizziness is absolutely not normal,” says Donnica Moore, M.D., president of Sapphire Women’s Health Group in Chester, N.J. “It tells you that something is wrong. It could be something simple and very easy to fix or it could be a sign of something else going on in your body.” Dizziness is a more common complaint among older adults—probably bec...
Source: Healthy Living - The Huffington Post - January 4, 2015 Category: Consumer Health News Source Type: news

How To Avoid China ’ s Medicine Monopoly
I want to share a shocking statistic with you… Around 80% of all the pharmaceuticals sold in America — both prescription and over-the-counter — are manufactured in China. I’m talking about drugs for Parkinson’s and Alzheimer’s, blood pressure and blood thinners, diuretics, aspirin, antibiotics, and a big chunk of the world’s insulin and diabetes drugs — just to name a few.1 We don’t even make penicillin anymore. The last penicillin plant in the U.S. closed its doors in 2004. Americans who rely on medicine are now almost entirely at the mercy of a country whose relations with the U.S. have become more ...
Source: Al Sears, MD Natural Remedies - September 19, 2023 Category: Complementary Medicine Authors: Jacob Tags: Health Source Type: news

Association of Traditional Chinese Medicine Therapy and the Risk of Vascular Complications in Patients With Type II Diabetes Mellitus: A Nationwide, Retrospective, Taiwanese-Registry, Cohort Study
This study investigated whether the concurrent TCM treatment reduces the risk of vascular complications in T2DM patients by using a large population from National Health Insurance Research Database (NHIRD). We identified 33,457 adult patients with newly diagnosed T2DM using anti-diabetic agents from a random sample of one million beneficiaries in the NHIRD between January 1, 2000 and December 31, 2011. We recruited 1049 TCM users (received TCM over 30 days with a diagnosis of T2DM) and randomly selected 4092 controls as the non-TCM cohort at a ratio of 1:4 frequency-matched by age, sex, hypertension, hyperlipidemia, and i...
Source: Medicine - January 1, 2016 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

5 Healthy Eating Habits To Adopt This Year
By Cynthia Sass, MPH, RD Nutrition is a hot topic these days, yet many of my clients still struggle with consistently following through with "the basics," and the stats show that missing the mark on many healthy habits is the norm. For example, the median daily intake of produce for U.S. adults is 1.1 servings of fruit and 1.6 servings of veggies, far below the minimum recommended five daily servings. If you're going to set just one goal for 2015, I think eating more produce should be it, but I've also listed four others below. I know you've heard them before, but they are without a doubt the most tried-and-true, impactf...
Source: Healthy Living - The Huffington Post - January 11, 2015 Category: Consumer Health News Source Type: news

Astragaloside IV promotes microglia/macrophages M2 polarization and enhances neurogenesis and angiogenesis through PPAR γ pathway after cerebral ischemia/reperfusion injury in rats.
Astragaloside IV promotes microglia/macrophages M2 polarization and enhances neurogenesis and angiogenesis through PPARγ pathway after cerebral ischemia/reperfusion injury in rats. Int Immunopharmacol. 2021 Jan 08;92:107335 Authors: Li L, Gan H, Jin H, Fang Y, Yang Y, Zhang J, Hu X, Chu L Abstract Microglia/macrophages play a dual role in brain injury and repair following cerebral ischemia/reperfusion. Promoting microglia/macrophage polarization from pro-inflammatory M1 to anti-inflammatory M2 phenotype has been considered as a potential treatment for ischemic stroke. Astragaloside IV (AS-IV) is a pr...
Source: International Immunopharmacology - January 8, 2021 Category: Allergy & Immunology Authors: Li L, Gan H, Jin H, Fang Y, Yang Y, Zhang J, Hu X, Chu L Tags: Int Immunopharmacol Source Type: research

Wine and chocolate may not 'beat diabetes'
This study does not give the green light to drink red wine above the recommended levels or to consume chocolate often – any potential benefits of diabetes prevention are likely to be overshadowed by the already known risks of excessive sugar, fat and alcohol consumption, including liver disease, cardiovascular disease, stroke and cancer.   Links To The Headlines Chocolate And Red Wine 'Can Beat Diabetes'. Sky News, January 20 2014 Chocolate and red wine can help stave off diabetes: High levels of antioxidants can regulate blood glucose levels. Daily Mail, January 20 2014 Red wine 'protects against diabetes' - and cho...
Source: NHS News Feed - January 20, 2014 Category: Consumer Health News Tags: Diabetes Food/diet Source Type: news

Gal-geun-dang-gwi-tang improves diabetic vascular complication in apolipoprotein E KO mice fed a western diet
Conclusions: These findings suggest that GGDGT attenuates endothelial dysfunction via improvement of the nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signalling pathway and improves insulin sensitivity in diabetic atherosclerosis.
Source: BMC Complementary and Alternative Medicine - November 22, 2014 Category: Complementary Medicine Authors: So LeeYun LeeJung ChoiMin KhoJung YoonSun ShinDae KangHo Lee Source Type: research

Does Diet Soda Cause Weight Gain?
This study shows quite nicely that non-caloric sweeteners can alter gut microbes in mice -- a change that has negative metabolic consequences -- and provides preliminary evidence that it can happen in humans too. Unexpected consequences To further appreciate how complicated our handling of diet soda can be, here's another little example: Our intestine (or bowel) is covered with cells that secrete hormones. These cells react to the presence and composition of food by secreting peptides such as glucagon-like peptide 1 (GLP-1), peptide YY (PYY) and cholecystokinin - these names are not important - that work on the brain, sig...
Source: Healthy Living - The Huffington Post - December 7, 2016 Category: Consumer Health News Source Type: news

The Global Epidemic of the Metabolic Syndrome
AbstractMetabolic syndrome, variously known also as syndrome X, insulin resistance, etc., is defined by WHO as a pathologic condition characterized by abdominal obesity, insulin resistance, hypertension, and hyperlipidemia. Though there is some variation in the definition by other health care organization, the differences are minor. With the successful conquest of communicable infectious diseases in most of the world, this new non-communicable disease (NCD) has become the major health hazard of modern world. Though it started in the Western world, with the spread of the Western lifestyle across the globe, it has become now...
Source: Current Hypertension Reports - February 26, 2018 Category: Primary Care Source Type: research

Identification of baicalin from Bofutsushosan and Daisaikoto as a potent inducer of glucose uptake and modulator of insulin signaling-associated pathways
Publication date: Available online 14 August 2018Source: Journal of Food and Drug AnalysisAuthor(s): Yu-Ting Kuo, Chih-Chan Lin, Hsiao-Tzu Kuo, Jui-Hsiang Hung, Ching-Hsuan Liu, Alagie Jassey, Ming-Hong Yen, Shu-Jing Wu, Liang-Tzung LinAbstractType 2 diabetes mellitus (T2DM) is a chronic disease characterized by hyperglycemia that can lead to long-term complications including heart diseases, stroke, retinopathy, and renal failure. Treatment strategies include stimulating glucose uptake and controlling blood glucose level. Bofutsushosan (BOF) and Daisaikoto (DAI) are two herb-based kampo medicines that have been demonstrate...
Source: Journal of Food and Drug Analysis - August 14, 2018 Category: Food Science Source Type: research

A clinical review of the effectiveness of tomato (Solanum lycopersicum) against cardiovascular dysfunction and related metabolic syndrome
In conclusion, consuming fresh tomato supplements may contribute to the prevention of obesity, diabetes and cardiovascular dysfunctions through positively affecting biochemical pathways associated with these conditions.
Source: Journal of Herbal Medicine - October 5, 2018 Category: Complementary Medicine Source Type: research