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A study of the allocation of energy consumption permits among the regions of China based on clustering analysis and cuckoo search
Environ Sci Pollut Res Int. 2021 Mar 13. doi: 10.1007/s11356-021-12905-x. Online ahead of print.ABSTRACTEnergy sources are power force of society and economy to develop. In recent years, extensive energy consumption patterns have threatened China's economic development step by step and made China's economic growth encounter unprecedented "bottlenecks." Therefore, this paper introduce a novel energy allocation scheme including cluster analysis and weighted voting allocation model to limit energy consumption in each region of China. The entire quota allocation process is divided into two parts by the proposed allocation sche...
Source: Environmental Science and Pollution Research International - March 13, 2021 Category: Environmental Health Authors: Zicheng Zhang Xiaolei Xu Source Type: research
The interplay of proactive personality and internship quality in Chinese university graduates' job search success: The role of career adaptability
Publication date: Available online 8 September 2018Source: Journal of Vocational BehaviorAuthor(s): Jingzhou Pan, Yanjun Guan, Jingru Wu, Lihong Han, Fei Zhu, Xinyu Fu, Jinmeng YuAbstractBased on the job characteristics model and career construction theory, this study examined the role of internship quality in the employment success of Chinese university students. A four-wave survey study was conducted in a sample of university graduates (N = 207) and the results showed that after the effects of baseline career adaptability (Time 1) were controlled, internship quality (Time 2) and proactive personality (Time 2) positiv...
Source: Journal of Vocational Behavior - September 9, 2018 Category: Psychiatry & Psychology Source Type: research
Identification of an Epidemiological Model to Simulate the COVID-19 Epidemic Using Robust Multiobjective Optimization and Stochastic Fractal Search.
Authors: Lobato FS, Libotte GB, Platt GM
Abstract
Traditionally, the identification of parameters in the formulation and solution of inverse problems considers that models, variables, and mathematical parameters are free of uncertainties. This aspect simplifies the estimation process, but does not consider the influence of relatively small changes in the design variables in terms of the objective function. In this work, the SIDR (Susceptible, Infected, Dead, and Recovered) model is used to simulate the dynamic behavior of the novel coronavirus disease (COVID-19), and its parameters are estimated by formulating a ro...
Source: Computational and Mathematical Methods in Medicine - October 22, 2020 Category: Statistics Tags: Comput Math Methods Med Source Type: research
Association Between The Search For Meaning In Life And Well-Being In Chinese Adolescents
AbstractTheories suggest that having a meaningful life has beneficial effects on adolescent well-being. Encouraging adolescents to search for meaning in their lives is therefore well advised. However, whether and how the search for meaning in life (SMIL) is related to adolescent well-being is unclear. Thus, this study tested the following two hypotheses, based on a sample of 1539 Chinese adolescents in the tenth grade (Mage = 15.8 years): 1) the SMIL promotes adolescent well-being ( “SMIL-as-promotor”), and 2) social connectedness mediates the link between the SMIL and adolescent well-being (“connectedness-as-me...
Source: Applied Research in Quality of Life - February 1, 2021 Category: International Medicine & Public Health Source Type: research
Studies on Activities and Chemical Characterization of Medicinal Plants in Search for New Antimalarials: A Ten Year Review on Ethnopharmacology
Malaria is an endemic disease that affected 229 million people and caused 409 thousand deaths, in 2019. Disease control is based on early diagnosis and specific treatment with antimalarial drugs since no effective vaccines are commercially available to prevent the disease. Drug chemotherapy has a strong historical link to the use of traditional plant infusions and other natural products in various cultures. The research based on such knowledge has yielded two drugs in medicine: the alkaloid quinine from Cinchona species, native in the Amazon highland rain forest in South America, and artemisinin from Artemisia annua, a spe...
Source: Frontiers in Pharmacology - September 22, 2021 Category: Drugs & Pharmacology Source Type: research
IJERPH, Vol. 18, Pages 11615: Short-Term Impacts of Meteorology, Air Pollution and Internet Search Data on Viral Diarrhea Infection among Children in Jilin Province, China
This study aimed to evaluate the short-term effects of temperature, precipitation, air quality, and social attention on children’s viral diarrhea in temperate regions of China by using the distribution lag nonlinear model (DLNM). We found that low temperature affected the increase in children’s viral diarrhea infection for about 1 week, while high temperature and heavy precipitation affected the increase in children’s viral diarrhea infection risk for at least 3 weeks. As the increase of the air pollution index may change the daily life of the public, the infection of children’s viral diarrhea can be restrained wit...
Source: International Journal of Environmental Research and Public Health - November 4, 2021 Category: Environmental Health Authors: Lu Li Li Ai Song Duan Yang Tags: Article Source Type: research
Association Between The Search For Meaning In Life And Well-Being In Chinese Adolescents
AbstractTheories suggest that having a meaningful life has beneficial effects on adolescent well-being. Encouraging adolescents to search for meaning in their lives is therefore well advised. However, whether and how the search for meaning in life (SMIL) is related to adolescent well-being is unclear. Thus, this study tested the following two hypotheses, based on a sample of 1539 Chinese adolescents in the tenth grade (Mage = 15.8 years): 1) the SMIL promotes adolescent well-being ( “SMIL-as-promotor”), and 2) social connectedness mediates the link between the SMIL and adolescent well-being (“connectedness-as-me...
Source: Applied Research in Quality of Life - November 23, 2021 Category: International Medicine & Public Health Source Type: research
Using a System Pharmacology Method to Search for the Potential Targets and Pathways of Yinqiaosan against COVID-19
J Healthc Eng. 2022 Mar 15;2022:9248674. doi: 10.1155/2022/9248674. eCollection 2022.ABSTRACTThe first reported case of coronavirus disease 2019 (COVID-19) occurred in Wuhan, Hubei, China. Thereafter, it spread through China and worldwide in only a few months, reaching a pandemic level. It can cause severe respiratory illnesses such as pneumonia and lung failure. Since the onset of the disease, the rapid response and intervention of traditional Chinese medicine (TCM) have played a significant role in the effective control of the epidemic. Yinqiaosan (YQS) was used to treat COVID-19 pneumonia, with good curative effects. Ho...
Source: Atherosclerosis - March 28, 2022 Category: Cardiology Authors: Li-Hua Cao Xing-Yuan Jia Hong-Juan He Zhen-Zhen Wang Yi-Ying Zhao Xue Yang Xiu-Min Li Ming-San Miao Source Type: research
A Background Search on the Potential Role of < em > Scutellaria < /em > and Its Essential Oils
Biomed Res Int. 2022 Jul 27;2022:7265445. doi: 10.1155/2022/7265445. eCollection 2022.ABSTRACTScutellaria (Lamiaceae), which contains over 350 species, usually known as skullcaps, is found throughout Europe, the United States, and East Asia. In traditional Chinese medicine, several species are used to wipe out heat-evil and remove surface ills (TCM). The current study examines the ethnopharmacology, biological activity, and chemical substances associated with Scutellaria species. More than 295 chemicals, including flavonoids and diterpenes, have been identified. Scutellaria and its active principles have been shown in stud...
Source: Biomed Res - August 15, 2022 Category: Research Authors: Mehrukh Zehravi Chenmala Karthika Abul Kalam Azad Zubair Ahmad Farhat S Khan Md Sohanur Rahman Rokeya Akter Md Habibur Rahman Source Type: research
Search for More Effective Microsatellite Markers for Forensics With Next-Generation Sequencing
Published by the Combined DNA Index System (CODIS) program of the Federal Bureau of Investigation (FBI) in 1997, the 13 core short tandem repeat (STR) loci are widely adopted as genetic markers in forensic applications, e.g., identity testing and paternity testing. However, these loci may be biased and suffer from reduced sensitivities toward specific population groups. In addition, the rapid growth of entries in forensic databases raises the chance of random hits, which can cause false recognitions of criminal suspects. A solution to these problems is to introduce more effective STR markers. The availability of whole geno...
Source: IEE Transactions on NanoBioscience - July 1, 2017 Category: Nanotechnology Source Type: research
Structure-based drug repositioning over the human TMPRSS2 protease domain: search for chemical probes able to repress SARS-CoV-2 Spike protein cleavages.
Abstract
In December 2019, a new coronavirus was identified in the Hubei province of central china and named SARS-CoV-2. This new virus induces COVID-19, a severe respiratory disease with high death rate. A putative target to interfere with the virus is the host transmembrane serine protease family member II (TMPRSS2). This enzyme is critical for the entry of coronaviruses into human cells by cleaving and activating the spike protein (S) of SARS-CoV-2. Repositioning approved, investigational and experimental drugs on the serine protease domain of TMPRSS2 could thus be valuable. There is no experimental structure f...
Source: European Journal of Pharmaceutical Sciences - July 26, 2020 Category: Drugs & Pharmacology Authors: Singh N, Decroly E, Khatib AM, Villoutreix BO Tags: Eur J Pharm Sci Source Type: research
Scaffold morphing of arbidol (umifenovir) in search of multi-targeting therapy halting the interaction of SARS-CoV-2 with ACE2 and other proteases involved in COVID-19.
Abstract
The rapid emergence of a novel coronavirus, SARS-coronavirus 2 (SARS-CoV-2), originated from Wuhan, China, imposed a global health emergency. Angiotensin-converting enzyme 2 (ACE2) receptor serves as an entry point for this deadly virus while the proteases like furin, transmembrane protease serine 2 (TMPRSS2) and 3 chymotrypsin-like protease (3CLpro) are involved in the further processing and replication of SARS-CoV-2. The interaction of SP with ACE2 and these proteases results in the SARS-CoV-2 invasion and fast epidemic spread. The small molecular inhibitors are reported to limit the interaction of SP w...
Source: Virus Research - August 27, 2020 Category: Virology Authors: Choudhary S, Silakari O Tags: Virus Res Source Type: research
In search of the essential woman in national development: China's first TV drama series on women, by women, for women
J Dev Comm. 1998 Dec;9(2):1-17.NO ABSTRACTPMID:12321944
Source: The Journal of Development Communication - September 27, 2002 Category: International Medicine & Public Health Authors: Y Chen Source Type: research
Plague vaccines: new developments in an ongoing search
Appl Microbiol Biotechnol. 2021 Jun 18. doi: 10.1007/s00253-021-11389-6. Online ahead of print.ABSTRACTAs the reality of pandemic threats challenges humanity, exemplified during the ongoing SARS-CoV-2 infections, the development of vaccines targeting these etiological agents of disease has become increasingly critical. Of paramount concern are novel and reemerging pathogens that could trigger such events, including the plague bacterium Yersinia pestis. Y. pestis is responsible for more human deaths than any other known pathogen and exists globally in endemic regions of the world, including the four corners region and North...
Source: Applied Microbiology and Biotechnology - June 18, 2021 Category: Microbiology Authors: Jason A Rosenzweig Emily K Hendrix Ashok K Chopra Source Type: research
