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Total 65 results found since Jan 2013.

Strong associations between current periodontal condition and stroke, but not past major cardiovascular events
Aim: To evaluate the association between current periodontal condition and past cardiovascular and stroke events in a cohort of patients treated for chronic coronary artery disease from a university hospital in Brazil.
Source: Atherosclerosis - August 1, 2017 Category: Cardiology Authors: Leopoldo Pentead Nucci, Irineu Gregnamin Pedron Source Type: research

Strong Associations Between Current Periodontal Condition And Early Stroke
Background and Aims: To evaluate the association between current periodontal condition, past cardiovascular and early stroke events in a cohort of patients treated for chronic coronary artery disease from a university hospital in S ão Paulo, Brazil.
Source: Atherosclerosis - August 4, 2019 Category: Cardiology Authors: L. Nucci Da Silva, I. Pedron Tags: Posters 26 - 29 May, 2019 Source Type: research

How John Fetterman Came Out of the Darkness
When he looks back on the past year—a year in which he nearly died, became a U.S. Senator, and nearly died again—it is the debate that John Fetterman identifies as the ­breaking point. “The debate lit the mitch,” he says, then shakes his head in frustration and tries again. The right word is there in his brain, but he struggles to get it out. “Excuse me, that should be lit the mitch—” He stops and tries again. “Lit the match,” he says finally. Oct. 25, 2022: the date is lodged in his mind. “I knew I had to do it,” he tells me. “I knew that the vote...
Source: TIME: Health - July 20, 2023 Category: Consumer Health News Authors: Molly Ball Tags: Uncategorized Congress Cover Story Exclusive feature uspoliticspolicy Source Type: news

More Research Is Needed on Lifestyle Behaviors That Influence Progression of Parkinson's Disease
This article highlights some of these challenges in the design of lifestyle studies in PD, and suggests a more coordinated international effort is required, including ongoing longitudinal observational studies. In combination with pharmaceutical treatments, healthy lifestyle behaviors may slow the progression of PD, empower patients, and reduce disease burden. For optimal care of people with PD, it is important to close this gap in current knowledge and discover whether such associations exist. Introduction Parkinson's disease (PD) is an age-related complex progressive neurodegenerative disorder, with key p...
Source: Frontiers in Neurology - April 29, 2019 Category: Neurology Source Type: research

Off-pump versus On-pump Coronary Artery Bypass Grafting in Frail Patients: Study Protocol for the FRAGILE Multicenter Randomized Controlled Trial
In this study, the authors introduce the new national, multicenter, randomized, controlled trial "FRAGILE", to be developed in the main cardiac surgery centers of Brazil, to clarify the potential benefit of off-pump CABG in frail patients. Methods: FRAGILE is a two-arm, parallel-group, multicentre, individually randomized (1:1) controlled trial which will enroll 630 patients with blinded outcome assessment (at 30 days, 6 months, 1 year, 2 years and 3 years), which aims to compare adverse cardiac and cerebrovascular events after off-pump versus on-pump CABG in pre-frail and frail patients. Primary outcomes will be all-cause...
Source: Revista Brasileira de Cirurgia Cardiovascular - December 5, 2017 Category: Cardiovascular & Thoracic Surgery Source Type: research

Comment The social sciences, humanities, and health
Humanities and social sciences have had many positive influences on health experiences, care, and expenditure. These include on self-management for diabetes, provision of psychological therapy, handwashing, hospital checklists, the Scottish Government's stroke guidelines, England's tobacco control strategy, the response to the Ebola outbreak in west Africa and Zika virus in Brazil, and many more.1 Researchers have shown time and time again the political, practical, economic, and civic value of education and research in disciplines like anthropology, history, and philosophy.
Source: LANCET - April 13, 2018 Category: General Medicine Authors: Martyn Pickersgill, Sarah Chan, Gill Haddow, Graeme Laurie, Devi Sridhar, Steve Sturdy, Sarah Cunningham-Burley Tags: Comment Source Type: research

A Polymorphism in Toll-like Receptor 2 Gene Is Associated with Occurrence of Bacterial Infections in Sickle Cell Disease Patients
Discussion: In SCD pts, TLR-2 rs4696480 TA genotype might be protective against bacterial infections, whereas TT genotype might increase risk of such infections. Previous reports demonstrated higher secretion of inflammatory factors in cells from AA individuals, lower occurrence and severity of immune diseases in T carriers. TA genotype might stand between deleterious effects of over inflammatory response (AA genotype) and under response (TT genotype) to infectious agents.DisclosuresNo relevant conflicts of interest to declare.
Source: Blood - November 21, 2018 Category: Hematology Authors: Tozatto-Maio, K., Girot, R., Ly, I. D., Rocha, V., Pinto, A. C. S., Diagne, I., Benzerara, Y., Dinardo, C. L., Kashima, S., Araujo, I. L., Kenzey, C., Fonseca, G. H. H., Rodrigues, E., Volt, F., Jarduli, L. R., Ruggeri, A., Mariaselvam, C. M., Gualandro, Tags: 113. Hemoglobinopathies, Excluding Thalassemia-Basic and Translational Science: Poster III Source Type: research

The First Baby Has Been Born After a Uterus Transplant From a Deceased Donor
The world’s first baby born by a uterus transplant from a deceased donor is healthy and nearing her first birthday, according to a new case study published Tuesday in the Lancet. Uterus transplants have become more common in recent years, resulting in 11 live births around the world. But all of the other successful deliveries so far have been made possible by living donors — often women who opt to donate their uterus to a close friend or family member without one. The birth resulting from the case detailed in the Lancet, which took place at Brazil’s Hospital das Clínicas last December, is both the f...
Source: TIME: Health - December 4, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized fertility healthytime Source Type: news

Evaluation of platelet activity by multiple electrode impedance aggregometry in acute coronary syndromes: pilot study in a Brazilian tertiary-care public hospital.
This study suggested that the evaluation of PA in ACS using MEA may identify non-responders to ASA. Larger studies are necessary to define, in a public health scenario, the value of MEA in the management of ACS. PMID: 30652826 [PubMed - in process]
Source: Braz J Med Biol Res - January 10, 2019 Category: Research Authors: De Lorenzo A, Dutra M, Mattos MA, Rey HCV, Tibirica E Tags: Braz J Med Biol Res Source Type: research

New sequence types of Acinetobacter baumannii in two emergency hospitals in the Central-West region of Brazil
In this report, we present a series of three cases of snakebites that evolved with hemorrhagic stroke due to delays in the access to antivenom in the Brazilian Amazon, being fundamental for diagnosis to validate the clinical suspicion and make decisions that would improve the treatment and prognosis of the patients.
Source: Revista da Sociedade Brasileira de Medicina Tropical - July 18, 2019 Category: Tropical Medicine Source Type: research

Erratum: Association between executive and food functions in the acute phase after stroke
ABSTRACT Aloysio de Castro (1881-1959) is now remembered as one of Brazil's greatest physicians and is considered the father of Brazilian neurological semiology. However, his interests went far beyond the realm of Medicine, and he became one of the most illustrious intellectuals of his time. In 1927, he gave a speech at the S ão Paulo Society of Artistic Culture on Frédéric Chopin and embarked on a journey across the composer's life and times, discussing the medical issues involving his death, as well as his lovers, his compositions, and the spiritual aspects of musical interpretation. Thus, Castro reinforced the bond s...
Source: Arquivos de Neuro-Psiquiatria - October 7, 2020 Category: Neurology Source Type: research

Hydrocephalous as a Complication of Perimesencephalic Nonaneurysmal Subarachnoid Hemorrhage
JLSM, male, 71 years old, admitted into a private hospital in the city of Joinville, Brazil, complaining of persistent and severe headache. The patient reported onset of the condition three days before, after sexual activity, associated with nausea, vomiting and dizziness. He has a medical history of epilepsy, under regular use of Phenobarbital. The physical examination evidenced slight nuchal rigidity. Cranial computed tomography (CT) showed subarachnoid hemorrhage (SAH) in cisterns around the brainstem (Fig.
Source: Journal of Stroke and Cerebrovascular Diseases - October 20, 2020 Category: Neurology Authors: Guilherme Zini Reis, Fernanda Subtil de Moraes Machado, Wladimir Kummer de Paula, Fl ávio Diniz Ribas, Felipe Ibiapina dos Reis Tags: Case Report Source Type: research

Effect of intravenous thrombolysis with alteplase on clinical efficacy, inflammatory factors, and neurological function in patients with acute cerebral infarction
This study aimed to explore the effect of intravenous thrombolysis with alteplase on clinical efficacy, inflammatory factors, and neurological function in patients with acute cerebral infarction. A total of 120 patients with acute cerebral infarction were divided into two groups by the random number table method, with 60 patients in each group: observation group (intravenous thrombolysis with alteplase) and control group (intravenous thrombolysis with batroxobin). The clinical efficacy after a 14-day treatment was observed. Serum C-reactive protein (CRP), tumor necrosis factor α (TNF-α), interleukin-6 (IL-6), CD62p, GMP-...
Source: Brazilian Journal of Medical and Biological Research - March 17, 2021 Category: Research Authors: Jinhua Wang Xia Fang Dongliang Wang Yuan Xiao Source Type: research