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Vaccination: Malaria Vaccine
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Total 1933 results found since Jan 2013.
Preliminary Evaluation of the Safety and Immunogenicity of an Antimalarial Vaccine Candidate Modified Peptide (IMPIPS) Mixture in a Murine Model.
Authors: Lambraño J, Curtidor H, Avendaño C, Díaz-Arévalo D, Roa L, Vanegas M, Patarroyo ME, Patarroyo MA
Abstract
Malaria continues being a high-impact disease regarding public health worldwide; the WHO report for malaria in 2018 estimated that ~219 million cases occurred in 2017, mostly caused by the parasite Plasmodium falciparum. The disease cost the lives of more than 400,000 people, mainly in Africa. In spite of great efforts aimed at developing better prevention (i.e., a highly effective vaccine), diagnosis, and treatment methods for malaria, no efficient solution to this disease has been advanced to dat...
Source: Journal of Immunology Research - February 22, 2020 Category: Allergy & Immunology Tags: J Immunol Res Source Type: research
Latin America Has Weak Defences Against the Pandemic
This article includes reporting by Ivet González in Havana, Mario Osava in Rio de Janeiro, and Orlando Milesi in Santiago.
The post Latin America Has Weak Defences Against the Pandemic appeared first on Inter Press Service.
Source: IPS Inter Press Service - Health - April 4, 2020 Category: International Medicine & Public Health Authors: Humberto Marquez Tags: Development & Aid Editors' Choice Featured Headlines Health Human Rights Latin America & the Caribbean Population Regional Categories Coronavirus COVID-19 ECLAC Pan-American Health Organization (PAHO) Poverty World Health Organ Source Type: news
Current Drugs with Potential for Treatment of COVID-19: A Literature Review.
CONCLUSION: All examined treatments, although potentiality effective against COVID-19, need either appropriate drug development or clinical trial to be suitable for clinical use.
PMID: 32251618 [PubMed - as supplied by publisher]
Source: J Pharm Pharm Sci - April 7, 2020 Category: Drugs & Pharmacology Authors: Md Insiat Islam Rabby Tags: J Pharm Pharm Sci Source Type: research
BCG Vaccine Fighting Coronavirus in South Asia
The map from the medical journal Plos Medicine displays BCG vaccination policy by country. Bacillus Calmette-Guérin vaccine is a vaccine primarily used against tuberculosis. Yellow: The country now has a universal BCG vaccination program. Blue: The country used to recommend BCG vaccination for everyone, but now does not. Red: The country never had a universal vaccination program.By Darini Rajasingham-SenanayakeCOLOMBO, Sri Lanka, Apr 20 2020 (IPS) Numerous studies in many parts of the world have linked the BCG (Bacillus Calmette-Guerin) vaccination, widely used in the developing world with fewer Coronavirus cases. This is...
Source: IPS Inter Press Service - Health - April 20, 2020 Category: International Medicine & Public Health Authors: Darini Rajasingham-Senanayake Tags: Development & Aid Economy & Trade Featured Global Headlines Health TerraViva United Nations Source Type: news
How a vaccine made of mosquito spit could help stop the next epidemic
Five years ago, in an office complex with a giant sculpture of a mosquito just northwest of Phnom Penh, Jessica Manning struck on a novel idea. Rather than spend more years in what felt like a futile search for a malaria vaccine, she would take on all mosquito-borne pathogens at once.
Source: Reuters: Health - June 12, 2020 Category: Consumer Health News Tags: healthNews Source Type: news
Development of Medicines for Infectious Diseases -Malaria.
Abstract
In developed countries, it is said that "threats of infectious diseases are already thought as things of the past". However, as you can see in the case of Ebola hemorrhagic fever that occurred in West Africa, this is a big mistake. Among infectious diseases, only smallpox has been successfully eradicated worldwide. In addition to the three major infectious diseases of HIV/AIDS, tuberculosis, and malaria, there is another group called emerging and reemerging infectious diseases. Recently, neglected tropical diseases (NTDs) have been listed as threats by the WHO, as have drug-resistant bacteria. The spread ...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - July 3, 2020 Category: Drugs & Pharmacology Authors: Kita K Tags: Yakugaku Zasshi Source Type: research
Transforming the Global Economy or Parachuting Cats into Borneo?
Credit: United Nations Office for Disaster Risk Reduction (UNDRR)By Lawrence SurendraBANGKOK, Thailand, Aug 24 2020 (IPS) The COVID 19 Pandemic continues relentlessly. Deaths approaching a million globally, 22 million infected and growing. Brazil, India, the US and Russia accounting for almost 50% of the total cases in the world.
Medically the promise of a vaccine is given as signs of hope; what surprises awaits us when such a vaccine is available, would be another story. Economically, to address the uncertainty and the grim future ahead, the UN, some governments and even Joe Biden the US Presidential hopeful, are waving ...
Source: IPS Inter Press Service - Health - August 24, 2020 Category: International Medicine & Public Health Authors: Lawrence Surendra Tags: Development & Aid Featured Global Headlines Health Humanitarian Emergencies IPS UN: Inside the Glasshouse Population Poverty & SDGs TerraViva United Nations Source Type: news
Development of sustainable research excellence with a global perspective on infectious diseases: Centre de Recherches M édicales de Lambaréné (CERMEL), Gabon.
Development of sustainable research excellence with a global perspective on infectious diseases: Centre de Recherches Médicales de Lambaréné (CERMEL), Gabon.
Wien Klin Wochenschr. 2021 Jan 04;:
Authors: Ramharter M, Agnandji ST, Adegnika AA, Lell B, Mombo-Ngoma G, Grobusch MP, McCall M, Muranaka R, Kreidenweiss A, Velavan TP, Esen M, Schaumburg F, Alabi A, Druml C, Mordmüller B, Köhler C, Kremsner PG
Abstract
Medical research in sub-Saharan Africa is of high priority for societies to respond adequately to local health needs. Often enough it remains a challenge to build up capacity in infrastruct...
Source: Wiener Klinische Wochenschrift - January 4, 2021 Category: General Medicine Authors: Ramharter M, Agnandji ST, Adegnika AA, Lell B, Mombo-Ngoma G, Grobusch MP, McCall M, Muranaka R, Kreidenweiss A, Velavan TP, Esen M, Schaumburg F, Alabi A, Druml C, Mordmüller B, Köhler C, Kremsner PG Tags: Wien Klin Wochenschr Source Type: research
Circumsporozoite Surface Protein-based malaria vaccines: a review.
Abstract
Malaria represents a serious public health problem, presenting with high rates of incidence, morbidity and mortality in tropical and subtropical regions of the world. According to the World Health Organization, in 2018 there were 228 million cases and 405 thousand deaths caused by this disease in the world, affecting mainly children and pregnant women in Africa. Despite the programs carried out to control this disease, drug resistance and invertebrate vector resistance to insecticides have generated difficulties. An efficient vaccine against malaria would be a strategy with a high impact on the eradicatio...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - February 5, 2021 Category: Tropical Medicine Authors: Almeida MEM, Vasconcelos MGS, Tarragô AM, Mariúba LAM Tags: Rev Inst Med Trop Sao Paulo Source Type: research
Open data on malaria genomes will help combat drug resistance
(Wellcome Trust Sanger Institute) Genome variation data on more than 7,000 malaria parasites from 28 endemic countries is released today. It has been produced by MalariaGEN, a data-sharing network of groups around the world who are working together to build high-quality data resources for malaria research and disease control. This open data release provides benchmark data on parasite genome variation that is needed in the search for new drugs and vaccines, and in the development of surveillance tools for malaria control and elimination.
Source: EurekAlert! - Infectious and Emerging Diseases - February 24, 2021 Category: Infectious Diseases Source Type: news
Determining seropositivity —A review of approaches to define population seroprevalence when using multiplex bead assays to assess burden of tropical diseases
Conclusions/SignificanceFor disease control programmes, seropositivity is a practical and easily interpretable health metric but determining appropriate cut-offs for positivity can be challenging. Considerations for optimal cut-off approaches should include factors such as methods recommended by previous research, transmission dynamics, and the immunological backgrounds of the population. In the absence of international standards for estimating seropositivity in a population, the use of consistent methods that align with individual disease epidemiological data will improve comparability between settings and enable the asse...
Source: PLoS Neglected Tropical Diseases - June 28, 2021 Category: Tropical Medicine Authors: YuYen Chan Source Type: research
The Gates Foundation ’s 2021 Report Shows That Childhood Vaccinations Dropped During the Pandemic—But There’s a Bright Side
This time last year, the Bill and Melinda Gates Foundation warned of a grim potential side effect from the COVID-19 pandemic: its disruptions to routine medical care could erase 25 years of progress on childhood vaccination, setting back global health by decades.
The 2021 installment of the foundation’s annual Goalkeepers report, which details progress on 18 metrics related to global health, equity and sustainability, contains some good news and some bad news. Childhood vaccination rates have suffered during the pandemic—but only about half as much as the Gates Foundation originally predicted, signaling that ma...
Source: TIME: Health - September 14, 2021 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized COVID-19 embargoed study healthscienceclimate Source Type: news
Google ’s AI Lab, DeepMind, Offers ‘Gift to Humanity’ with Protein Structure Solution
Matt Higgins and his team of researchers at the University of Oxford had a problem.
For years, they had been studying the parasite that spreads malaria, a disease that still kills hundreds of thousands of people every year. They had identified an important protein on the surface of the parasite as a focal point for a potential future vaccine. They knew its underlying chemical code. But the protein’s all-important 3D structure was eluding them. That shape was the key to developing the right vaccine to slide in and block the parasite from infecting human cells.
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Source: TIME: Science - July 28, 2022 Category: Science Authors: Billy Perrigo Tags: Uncategorized Artificial Intelligence biztech2030 Source Type: news
The battle against malaria in Africa has stalled. Can research in Mozambique explain why?
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Moisés Mapanga, a burly man of 49, is the bait. At 6 p.m. on a mid-April evening, he climbs into an orange tent outside his one-room house in Matutuíne, a hot, swampy district near Maputo, the cap...
Source: Science of Aging Knowledge Environment - September 8, 2022 Category: Geriatrics Source Type: research
Plasmodium vivax vaccine: What is the best way to go?
Malaria is one of the most devastating human infectious diseases caused by Plasmodium spp. parasites. A search for an effective and safe vaccine is the main challenge for its eradication. Plasmodium vivax is the second most prevalent Plasmodium species and the most geographically distributed parasite and has been neglected for decades. This has a massive gap in knowledge and consequently in the development of vaccines. The most significant difficulties in obtaining a vaccine against P. vivax are the high genetic diversity and the extremely complex life cycle. Due to its complexity, studies have evaluated P. vivax antigens ...
Source: Frontiers in Immunology - January 16, 2023 Category: Allergy & Immunology Source Type: research
