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Vaccination: Malaria Vaccine

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Total 1933 results found since Jan 2013.

Viral vector and nucleic acid vaccines against COVID-19: A narrative review
After about 2 years since the first detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in Wuhan, China, in December 2019 that resulted in a worldwide pandemic, 6.2 million deaths have been recorded. As a result, there is an urgent need for the development of a safe and effective vaccine for coronavirus disease 2019 (COVID-19). Endeavors for the production of effective vaccines inexhaustibly are continuing. At present according to the World Health Organization (WHO) COVID-19 vaccine tracker and landscape, 153 vaccine candidates are developing in the clinical phase all over the world. Some n...
Source: Frontiers in Microbiology - August 31, 2022 Category: Microbiology Source Type: research

New data buoy hopes for promising malaria vaccine —but questions remain
A new vaccine against malaria showed promising preliminary results in a large trial in four African countries, boosting hopes that an additional tool may soon be available to help control the deadly disease. The vaccine, named R21/Matrix-M and developed by researchers at the University of Oxford, produced similarly impressive results in a small trial last year , but the current study posed a stiffer test of its protection. Initial data from the trial, reported yesterday at the American Society of Tropical Medicine and Hygiene meeting in Seattle, suggest the vaccine had an efficacy higher than 70% in regions...
Source: ScienceNOW - November 3, 2022 Category: Science Source Type: news

Isolation, Purification, and Characterization of Homogenous Novel Bioactive Protein from < em > Datura stramonium < /em > Stem Exhibited Larvicidal Activity against < em > Anopheles stephensi < /em >
J Trop Med. 2022 Dec 5;2022:1637896. doi: 10.1155/2022/1637896. eCollection 2022.ABSTRACTThe insecticidal resistance of mosquitoes necessitates the development of a natural, safe, and plant-based method for vector control. Unfortunately, there are no effective vaccines or particular medications available to combat malaria; therefore, mosquitoes must be targeted directly. Previous studies have shown the health benefits of Datura stramonium, but its bioactive peptides or proteins are less explored. This is the first study on D. stramonium stem protein used for mosquito larval protein. The present study aimed to identify the ...
Source: Journal of Tropical Medicine - December 15, 2022 Category: Tropical Medicine Authors: Manisha Kirar S P Singh Neelam Sehrawat Source Type: research

Identifying and Managing Vector-Borne Diseases in Migrants and Recent Travelers in the Emergency Department
AbstractPurpose of ReviewRecognition and treatment of neglected tropical and vector-borne diseases is paramount as travel and immigration resume after a brief lull during the COVID-19 pandemic. These patients often present initially to the emergency department, and increasing physician knowledge of symptoms and treatment can reduce morbidity and mortality. This paper aims to summarize typical presentations of common tropical diseases, both neglected and vector borne, and provide the emergency physician with a diagnostic pathway based on current recommendations.Recent FindingsCo-circulation of ZIKV, CHIKV, and DENV is incre...
Source: Current Emergency and Hospital Medicine Reports - April 26, 2023 Category: Emergency Medicine Source Type: research

The immunity modulation of transforming growth factor- β in malaria and other pathological process
Int Immunopharmacol. 2023 Jul 17;122:110658. doi: 10.1016/j.intimp.2023.110658. Online ahead of print.ABSTRACTThe main causative agent of malaria in humans is Plasmodium falciparum, which is spread through biting Anopheles mosquitoes. Immunoregulation in the host involving the pleiotropic cytokine transforming growth factor-β (TGF-β) has a vital role in controlling the immune response to P. falciparum infection. Based on a search of the published literature, this study investigated the correlation between malaria and immune cells, specifically the role of TGF-β in the immune response. The studies analyzed showed that, w...
Source: International Immunopharmacology - July 19, 2023 Category: Allergy & Immunology Authors: Shuang Wu Qing Nie Shuang Tan Guoyan Liao Yinyi Lv Caohua Lv Guang Chen Shuangchun Liu Source Type: research

Genetically Modified (GM) Mosquito Use to Reduce Mosquito-Transmitted Disease in the US: A Community Opinion Survey
Conclusion We present the first community-based survey of resident attitudes towards GMO mosquitoes in a region of a U.S. state in which Aedes-associated infectious disease risks are extant. Gender and individual risk-perception were found to be highly predictive of support or opposition to GM mosquito use. These findings may help public health practitioners and policymakers to improve communication and dialogue with the public around potential use of GM mosquitoes in the future, which may be increasingly important as new mosquito-borne threats such as Zika emerge. Competing Interest Statement The authors have declared th...
Source: PLOS Currents Outbreaks - May 25, 2016 Category: Epidemiology Authors: ameshadalja Source Type: research

Could there be a ' social vaccine ' for malaria?
Malaria is a global killer and a world health concern. But while millions of dollars are spent each year searching for innovative health solutions, new research suggests part of the answer may begin with mothers in the classroom. The research found that maternal education can act as a ' social vaccine ' for childhood malaria infection. The higher a mother ' s education, the lesser chance of their child being infected with malaria.
Source: ScienceDaily Headlines - May 9, 2017 Category: Science Source Type: news

Could there be a 'social vaccine' for malaria?
(University of Alberta Faculty of Medicine& Dentistry) Malaria is a global killer and a world health concern. But while millions of dollars are spent each year searching for innovative health solutions, new research from the University of Alberta suggests part of the answer may begin with mothers in the classroom.The research, published in the journal Pathogens and Global Health, found that maternal education can act as a 'social vaccine' for childhood malaria infection. The higher a mother's education, the lesser chance of their child being infected with malaria.
Source: EurekAlert! - Infectious and Emerging Diseases - May 9, 2017 Category: Infectious Diseases Source Type: news

Pharmacotherapy Interventions and Barriers to Treatment of Sickle Cell Disease in Ibadan, Nigeria
Conclusions:The most common treatment for SCD was folate therapy, followed by HU. Many patients receiving HU were formerly or currently enrolled in the clinical trials being run at UCH, which may suggest that it is not commonly prescribed by their regular providers. Most patients had faced at least one complication from SCD, and feel that their biggest deficits in treatment of SCD stem from their inability to get to a clinic or hospital in the event of a complication, and lack of information of the breadth of options that exist for management. More investigation remains to be done about the reasons for decreased usage of H...
Source: Blood - November 21, 2018 Category: Hematology Authors: Adimora, I., Akingbola, T. S., Lansigan, F., van Hoff, J. Tags: 901. Health Services Research-Non-Malignant Conditions: Poster II Source Type: research

Top Global Health Moments of 2021
By The Editorial Team, IntraHealth International Chemutai, a health worker at the Kaproron Health Center IV in Kween District, Uganda, stands in the operating room for maternal care, which officially opened in May 2020. Photo by Esther Ruth Mbabazi for IntraHealth International.December 21, 2021COVID-19 dominated the news cycle this year. The first large-scale global pandemic in 100 years has now killed more than5 million peopleworldwide since it began in 2020. Over 275 million people have been diagnosed with it. And at least115,000 health workers have lost their lives to the virus, though the number is likely muc...
Source: IntraHealth International - December 21, 2021 Category: International Medicine & Public Health Authors: kseaton Tags: HIV & AIDS COVID-19 Maternal, Newborn, Child Health Mental Health Noncommunicable Diseases 2021 Year of the Health and Care Worker Health Workforce Systems Health Workers Source Type: news

Health Problems Encountered by Short-Term European Volunteers in a Nongovernmental Organization in Cambodia
This study aimed to identify the health problems encountered by European short-term volunteers collaborating for 1 month with a nongovernmental organization (NGO) in Cambodia and to describe their characteristics. A prospective, descriptive observational study was conducted on short-term volunteers who collaborated with an NGO in Cambodia during August 2018. Informed consent and sociodemographic, clinical, and preventative health-related questionnaire data were provided by 198 volunteers. The health problems encountered were confirmed in a primary care consultation with healthcare professionals. Univariate and bivariate an...
Source: The American Journal of Tropical Medicine and Hygiene - January 10, 2022 Category: Tropical Medicine Authors: Jaime Barrio Cortes Claudia Rojas Mu ñoz Miguel Ángel Acosta Benito Ángela Hidalgo Baz Ángel Vicario Merino Mar ía Teresa Beca Martínez Montserrat Ruiz L ópez Source Type: research