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Total 214 results found since Jan 2013.
Phase 1 healthy volunteer willingness to participate and enrollment preferences.
CONCLUSION: Our results suggest that healthy volunteers are willing to participate in a wide range of types of phase 1 clinical trials, and express preferences for low risk and familiar studies and study procedures, preferences which are partially affected by offers of payment.
PMID: 28766409 [PubMed - as supplied by publisher]
Source: Clinical Trials - August 1, 2017 Category: Research Authors: Chen SC, Sinaii N, Bedarida G, Gregorio MA, Emanuel E, Grady C Tags: Clin Trials Source Type: research
Immersive virtual reality as a teaching tool for neuroanatomy
ConclusionImmersive VR educational tools awarded a more positive learner experience and enhanced student motivation. However, the technology was equally as effective as the traditional text books in teaching neuroanatomy.
Source: International Forum of Allergy and Rhinology - July 1, 2017 Category: Allergy & Immunology Authors: Katelyn Stepan, Joshua Zeiger, Stephanie Hanchuk, Anthony Del Signore, Raj Shrivastava, Satish Govindaraj, Alfred Iloreta Tags: ORIGINAL ARTICLE Source Type: research
The Role and Treatment Implications of Peripheral and Central Processing of Pain, Pruritus, and Nausea in Heightened Somatic Awareness: A Review
This article reviews the acute neural transmission of pain, pruritus, and nausea symptoms, which can begin in the periphery and/or viscera. The subsequent multiple pathways in the central nervous system that become involved in the processing of these symptoms are also discussed. The authors describe human brain imaging studies that have revealed consistent cortical and subcortical networks activated by these symptoms, including sensory, limbic, and associative regions. In particular, the authors discuss information revealed by the studies regarding the primary somatosensory cortex, secondary somatosensory cortex, anterio...
Source: Innovations in Clinical Neuroscience - June 1, 2017 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Neurologic Systems and Symptoms Neurology Pain Review central processing nausea pruritus Source Type: research
Utility of early postoperative imaging after combined endoscopic and open ventral skull base surgery.
CONCLUSION: The benefit of early postoperative imaging to detect complications after combined SBS was limited. In this cohort of patients, positive imaging findings' effects on patient management were dictated by the presence of supporting clinical symptoms.
PMID: 28490405 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - May 1, 2017 Category: ENT & OMF Authors: Mendelson ZS, Echanique KA, Crippen MM, Vazquez A, Liu JK, Eloy JA Tags: Am J Rhinol Allergy Source Type: research
Endoscopic endonasal nasopharyngectomy: tensor veli palatine muscle as a landmark for the parapharyngeal internal carotid artery
ConclusionThe PPICA was located in the same sagittal plane as the TVP muscle during dissection posteriorly. The PPICA appeared to lie around 2 cm laterally from the midline at around 2 cm in depth from the posterior margin of the TVP muscle. However, the exact position of the PPICA should be assessed using preoperative magnetic resonance imaging and intraoperative image‐guided systems.
Source: International Forum of Allergy and Rhinology - April 1, 2017 Category: Allergy & Immunology Authors: Chiung ‐Lin Liu, Ning‐I Hsu, Ping‐Hung Shen Tags: ORIGINAL ARTICLE Source Type: research
A delayed reaction to the magnetic resonance imaging contrast agent gadobutrol
Publication date: Available online 30 January 2017 Source:The Journal of Allergy and Clinical Immunology: In Practice Author(s): Hiroshi Nagai, Chikako Nishigori
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 30, 2017 Category: Allergy & Immunology Source Type: research
The Generation R Study: design and cohort update 2017
AbstractThe Generation R Study is a population-based prospective cohort study from fetal life until adulthood. The study is designed to identify early environmental and genetic causes and causal pathways leading to normal and abnormal growth, development and health from fetal life, childhood and young adulthood. This multidisciplinary study focuses on several health outcomes including behaviour and cognition, body composition, eye development, growth, hearing, heart and vascular development, infectious disease and immunity, oral health and facial growth, respiratory health, allergy and skin disorders of children and their ...
Source: European Journal of Epidemiology - January 8, 2017 Category: Epidemiology Source Type: research
Using imaging as a biomarker for asthma
There have been significant advancements in the various imaging techniques being used for the evaluation of asthmatic patients, both from a clinical and research perspective. Imaging characteristics can be used to identify specific asthmatic phenotypes and provide a more detailed understanding of endotypes contributing to the pathophysiology of the disease. Computed tomography, magnetic resonance imaging, and positron emission tomography can be used to assess pulmonary structure and function. It has been shown that specific airway and lung density measurements using computed tomography correlate with clinical parameters, i...
Source: Journal of Allergy and Clinical Immunology - December 31, 2016 Category: Allergy & Immunology Authors: Abhaya Trivedi, Chase Hall, Eric A. Hoffman, Jason C. Woods, David S. Gierada, Mario Castro Tags: Reviews and feature article Source Type: research
Pathophysiology of Immediate Reactions to Injectable Gadolinium-based Contrast Agents
Conclusion: As GBCAs are widely used for the diagnosis and monitoring of disease, the incidence of adverse drug reactions to GBCA warrants ongoing development of approaches to diagnosis and avoidance of these adverse events.
Source: Topics in Magnetic Resonance Imaging - December 1, 2016 Category: Radiology Tags: Review Articles Source Type: research
Clinical potential for imaging in patients with asthma and other lung disorders
The ability of lung imaging to phenotype patients, determine prognosis, and predict response to treatment is expanding in clinical and translational research. The purpose of this perspective is to describe current imaging modalities that might be useful clinical tools in patients with asthma and other lung disorders and to explore some of the new developments in imaging modalities of the lung. These imaging modalities include chest radiography, computed tomography, lung magnetic resonance imaging, electrical impedance tomography, bronchoscopy, and others.
Source: Journal of Allergy and Clinical Immunology - November 17, 2016 Category: Allergy & Immunology Authors: Emily M. DeBoer, David R. Spielberg, Alan S. Brody Tags: Reviews and feature article Source Type: research
Journal Allergy & Clinical Immunology Perspective: Clinical potential for imaging in asthma and other lung disorders
The ability of lung imaging to phenotype patients, determine prognosis, and to predict response to treatments is expanding in clinical and translational research. The purpose of this perspective is to describe current imaging modalities that may be useful clinical tools in asthma and other lung disorders and to explore some of the new developments in imaging modalities of the lung. These imaging modalities include chest radiography (CXR), computed tomography (CT), lung magnetic resonance imaging (MRI), electrical impedance tomography (EIT), bronchoscopy, and others.
Source: Journal of Allergy and Clinical Immunology - November 17, 2016 Category: Allergy & Immunology Authors: Emily M. DeBoer, David R. Spielberg, Alan S. Brody Source Type: research
Cardiac magnetic resonance imaging for the diagnosis and follow-up of Loeffler's endocarditis
Loeffler's endocarditis (LE) is an acute form of primary restrictive cardiomyopathy. Patients affected often have a hypereosinophilic syndrome and cardiac involvement. Hypereosinophilia and cardiac involvement are also seen in the allergic eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome). Warfarin is generally indicated because of association between LE and embolic events.
Source: Journal of Allergy and Clinical Immunology - October 13, 2016 Category: Allergy & Immunology Authors: Grazia Casavecchia, Matteo Gravina, Michele Correale, Antonio Totaro, Luca Macarini, Matteo Di Biase, Natale Daniele Brunetti Tags: Letter to the Editor Source Type: research
Nanoscale Particulate Matter from Urban Traffic Rapidly Induces Oxidative Stress and Inflammation in Olfactory Epithelium with Concomitant Effects on Brain
Conclusions: These findings show the differential time course of oxidative stress and inflammatory responses to nPM between the OE and the brain. Slow cumulative transport of inhaled nPM into the brain may contribute to delayed responses of proximal and distal brain regions, with potential input from systemic factors.
Citation: Cheng H, Saffari A, Sioutas C, Forman HJ, Morgan TE, Finch CE. 2016. Nanoscale particulate matter from urban traffic rapidly induces oxidative stress and inflammation in olfactory epithelium with concomitant effects on brain. Environ Health Perspect 124:1537–1546; http://dx.doi.org/10.1289/EHP13...
Source: EHP Research - September 30, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article October 2016 Source Type: research
Prediction of the originating site of sinonasal inverted papilloma by preoperative magnetic resonance imaging and computed tomography
ConclusionsPreoperative combination of MRI and CT provides a better option to accurately predict the SNIP originating site, and thus may facilitate accurate and complete excision of the SNIP.
Source: International Forum of Allergy and Rhinology - July 31, 2016 Category: Allergy & Immunology Authors: Gaoli Fang, Hongfei Lou, Wenling Yu, Xiangdong Wang, Bentao Yang, Junfang Xian, Xiaohong Song, Erzhong Fan, Ying Li, Chengshuo Wang, Luo Zhang Tags: ORIGINAL ARTICLE Source Type: research
