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Infectious Disease: Outbreaks
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Total 533 results found since Jan 2013.
Rapid development in Central Africa increases the risk of infectious disease outbreaks
(NIH/National Institute of Allergy and Infectious Diseases) The Central Africa region is experiencing rapid urbanization, economic growth and infrastructure development. These changes, while generally positive, also make the region more vulnerable to infectious disease outbreaks. Efforts to build up the health care infrastructure in Central Africa are critically needed to mitigate or prevent a large outbreak of Ebola or other infectious disease in the region. The authors represent 12 different organizations, including the National Institute of Allergy and Infectious Diseases.
Source: EurekAlert! - Infectious and Emerging Diseases - August 22, 2018 Category: Infectious Diseases Source Type: news
Genomic analysis offers insight into 2018 Nigeria Lassa fever outbreak
(NIH/National Institute of Allergy and Infectious Diseases) A surge in Lassa fever cases in Nigeria in 2018 doesn't appear to be linked to a single virus strain or increased human-to-human transmission, according to genomic analysis published in NEJM. Multiple institutions collaborated on the report, and the research was supported in part by the National Institute of Allergy and Infectious Diseases, the National Human Genome Research Institute, and the NIH Common Fund's Human Heredity and Health in Africa Program, all components of NIH.
Source: EurekAlert! - Infectious and Emerging Diseases - October 17, 2018 Category: Infectious Diseases Source Type: news
Surface (S) Layer Proteins of Lactobacillus acidophilus Block Virus Infection via DC-SIGN Interaction
We describe the unexpected binding of S-layer to cells devoid of DC-SIGN but also confirm that the presence of DC-SIGN was essential for S-layer’s antiviral activity. S-layer protein exerted its antiviral effect with different kinetics than mannan, a known viral inhibitor that also acts on DC-SIGN (Yu et al., 2017). Together our results suggest that inhibition of viral entry by S-layer occurs via a novel S-layer/DC-SIGN interaction.
Materials and Methods
Isolation of S-Layer Proteins
S-layer proteins were extracted from overnight cultures of L. acidophilus ATCC 4356 cells grown in MRS medium at 37°C by usi...
Source: Frontiers in Microbiology - April 15, 2019 Category: Microbiology Source Type: research
The Human Upper Respiratory Tract Epithelium Is Susceptible to Flaviviruses
In this study, we exposed apically well-differentiated human NECs cultured at the ALI to the related flaviviruses ZIKV, JEV, WNV, and Usutu virus (USUV). We selected these viruses due to the recent increasing evidences of potential threat to humans (Cadar et al., 2017; Simonin et al., 2018). We show that NECs are particularly susceptible to JEV and WNV infection and to other flaviviruses included in this study. Infection with each virus led to shedding of infectious virus particles through the apical and basolateral surfaces and triggered host mechanisms at the level of inflammatory and antiviral mediators....
Source: Frontiers in Microbiology - April 15, 2019 Category: Microbiology Source Type: research
The Future of Flu: A Review of the Human Challenge Model and Systems Biology for Advancement of Influenza Vaccinology
Conclusions: Human challenge studies and systems biology approaches are important tools that should be used in concert to advance our understanding of influenza infection and provide targets for novel therapeutics and immunizations.
Introduction
Although influenza virus was recognized as an important pathogen over a century ago, influenza continues to cause a significant burden of disease. In the United States alone, it's estimated that in the 2017–2018 season there were 959,000 hospitalizations related to influenza illness, and 79,400 deaths (CDC, 2018). Worldwide, WHO estimates that annual influen...
Source: Frontiers in cellular and infection microbiology - April 16, 2019 Category: Microbiology Source Type: research
Decline in measles vaccination is causing a preventable global resurgence of the disease
(NIH/National Institute of Allergy and Infectious Diseases) In 2000, measles was declared to be eliminated in the United States. Today, the US and many other countries are experiencing outbreaks of measles because of declines in measles vaccine coverage. Without renewed focus on vaccination efforts, the disease may rebound in full force, according to a commentary in NEJM by infectious diseases experts at the National Institute of Allergy and Infectious Diseases and Penn State University College of Medicine's Milton S. Hershey Medical Center.
Source: EurekAlert! - Infectious and Emerging Diseases - April 18, 2019 Category: Infectious Diseases Source Type: news
NIAID officials discuss novel Coronavirus that recently emerged in China
(NIH/National Institute of Allergy and Infectious Diseases) The new cluster of viral pneumonia cases originating in Wuhan, China, marks the third time in 20 years that a member of the large family of coronaviruses (CoVs) has jumped from animals to humans and sparked an outbreak. In a new JAMA Viewpoint essay, Anthony S. Fauci, M.D., director of the NIH's National Institute of Allergy and Infectious Diseases (NIAID), looks back at two earlier novel CoV outbreaks that initially caused global havoc and describes steps needed to contain the current one.
Source: EurekAlert! - Infectious and Emerging Diseases - January 23, 2020 Category: Infectious Diseases Source Type: news
Is It Allergies, The Flu Or The Coronavirus? How To Tell The Difference
(CNN) — The coronavirus has infected more than 100,000 people worldwide. With all of the news of event cancellations, empty flights and health precautions (wash your hands!), it’s natural that people may get a little anxious every time they feel a tickle in their throat or the beginnings of a bad cough.
While the coronavirus is certainly something to take seriously, the chances of any individual person getting it are still low. But if you’re wondering whether that stuffy nose could end up being a worst case scenario, CNN talked to Dr. Greg Poland, a professor of medicine and Infectious diseases at the May...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - March 11, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Coronavirus Source Type: news
On endocrine disruption at the workplace – how to get from suggestive to conclusive evidence?
Unusual clusters and outbreaks of reproductive disorders during past decades remind us of the devastating health consequences and human suffering to which exposure to industrial chemicals and pharmaceuticals may give rise. Birth defects caused by gestational exposure to thalidomide, vaginal cancer by diethylstilbestrol, azoospermia by dibromochloropropane, cerebral palsy by methyl mercury, and fetal wasting syndrome by chlorinated biphenyls are all inscribed in medical history as tragic mementos of ignorance and neglect in the past (1).
In parallel with the fast-increasing entrance of women into the workforce, interest ...
Source: Scandinavian Journal of Work, Environment and Health - April 16, 2020 Category: Occupational Health Tags: Editorial Source Type: research
‘Superforecasters’ Are Making Eerily Accurate Predictions About COVID-19. Our Leaders Could Learn From Their Approach
When Dr. Anthony Fauci said in late May that there’s a “good chance” a COVID-19 vaccine will be ready by the end of this year, Steve Roth badly wanted to believe him. Roth, a 74-year-old New Yorker who endured fever, pneumonia and anxiety while fighting the virus, wants life to go back to normal as much as anyone. And he respects Fauci, the longtime head of the National Institute of Allergy and Infectious Diseases (NIAID), ”an awful lot,” he says. But he just doesn’t think Fauci’s timeline is realistic. Instead, he’s putting his proverbial money on mid 2021.
“Like every...
Source: TIME: Health - June 11, 2020 Category: Consumer Health News Authors: Tara Law Tags: Uncategorized Source Type: news
Moderna ’s COVID-19 Vaccine Enters Final Testing Phase, As Researchers Dose the Study’s First Volunteer
Moderna Therapeutics and the National Institute of Allergy and Infectious Diseases (NIAID) announced today that researchers had injected the first volunteer in the first U.S. coronavirus vaccine to reach the final, phase 3 stage of testing.
That person received the shot at 6:45 am eastern time in Savannah, Geo., Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases of the National Institutes of Health (NIH) told reporters during a briefing. Because the trial will randomly assign participants to receive either the vaccine or a placebo, and neither the researchers nor the volunteers will kn...
Source: TIME: Health - July 27, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news
NIAID funds new influenza research network
(NIH/National Institute of Allergy and Infectious Diseases) The National Institute of Allergy and Infectious Diseases has established a network of research sites to study the natural history, transmission and pathogenesis of influenza and provide an international research infrastructure to address influenza outbreaks. The program, called the Centers of Excellence for Influenza Research and Response (CEIRR), is expected to be supported for seven years by NIAID contracts to five institutions. Funding for the first year of the contracts will total approximately $24 million.
Source: EurekAlert! - Infectious and Emerging Diseases - April 14, 2021 Category: Infectious Diseases Source Type: news
An outbreak of anaphylactic transfusion reactions to group B plasma and platelets and its possible relationship to Alpha-Gal syndrome
DISCUSSION: AGS is an emerging problem which may have implications for blood transfusion practice. Avoidance of blood group B antigen containing components may be prudent in non-blood group B patients with established AGS. Investigation for AGS should be considered in the evaluation of anaphylactic transfusion reactions.PMID:37642435 | DOI:10.1111/trf.17521
Source: Transfusion - August 29, 2023 Category: Hematology Authors: Colleen W Gilstad Kathleen Conry-Cantilena Roya Zarpak Anne F Eder Source Type: research
'Alien' wildlife in Europe wreaks €12bn damage a year, study shows
From tiger mosquitoes to ragweed, more than 10,000 invasive species are putting increasing pressure on the natural worldAnimals and plants brought to Europe from other parts of the world are a bigger-than-expected threat to health and the environment costing at least €12bn (£10bn) a year, according to a study published on Thursday.More than 10,000 "alien" species have gained a foothold in Europe, from Asian tiger mosquitoes to North American ragweed, and at least 1,500 are known to be harmful, the European Environment Agency (EEA) said."In many areas, ecosystems are weakened by pollution, climate change and fragmentatio...
Source: Guardian Unlimited Science - February 21, 2013 Category: Science Tags: Biodiversity Biology World news guardian.co.uk Endangered species Europe Animals Plants Zoology Conservation Environment Invasive species Science Wildlife Source Type: news
