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Impact of atrial fibrillation on the outcomes of transcatheter mitral valve repair using MitraClip: a systematic review and meta-analysis
AbstractAtrial fibrillation (AF) is a common arrhythmia in patients with mitral regurgitation (MR) undergoing transcatheter mitral valve repair (TMVR). In this systematic review, we aimed to investigate the outcomes of TMVR using MitraClip in AF patients. We performed a systematic search using PubMed, SCOPUS, EMBASE, and Google Scholar, from inception to May 10, 2020, for studies that reported outcomes following MitraClip, in patients with AF versus without AF. Seven studies with a total of 7678 patients met the inclusion criteria. The risk of 1-year all-cause mortality following TMVR was higher in AF patients (RR 1.40, 95...
Source: Heart Failure Reviews - November 10, 2020 Category: Cardiology Source Type: research

Anticoagulation following mitral valve repair
ConclusionsOur analysis showed that postoperative warfarin use was associated with an overall reduced composite of bleeding and thromboembolic incidents and superior long ‐term survival. These findings suggest that anticoagulation with warfarin following mitral valve repair may be a safe and effective means for avoiding postoperative complications and that a large prospective randomized clinical trial is warranted.
Source: Journal of Cardiac Surgery - October 21, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Tessa M. F. Watt, Shannon L. Murray, Alexander A. Brescia, David A. Burn, Alexander Wisniewski, Shazli P. Khan, Matthew A. Romano, Steven F. Bolling, The Michigan Mitral Research Group (MMRG) Tags: ORIGINAL ARTICLE Source Type: research

Contemporary Diagnosis and Management of Rheumatic Heart Disease: Implications for Closing the Gap: A Scientific Statement From the American Heart Association.
Stroke Nursing; and Council on Clinical Cardiology Abstract The global burden of rheumatic heart disease continues to be significant although it is largely limited to poor and marginalized populations. In most endemic regions, affected patients present with heart failure. This statement will seek to examine the current state-of-the-art recommendations and to identify gaps in diagnosis and treatment globally that can inform strategies for reducing disease burden. Echocardiography screening based on World Heart Federation echocardiographic criteria holds promise to identify patients earlier, when prophylaxis is more...
Source: Circulation - October 19, 2020 Category: Cardiology Authors: Kumar RK, Antunes MJ, Beaton A, Mirabel M, Nkomo VT, Okello E, Regmi PR, Reményi B, Sliwa-Hähnle K, Zühlke LJ, Sable C, American Heart Association Council on Lifelong Congenital Heart Disease and Heart Health in the Young; Council on Cardiovascular and Tags: Circulation Source Type: research

Impact of atrial fibrillation on outcomes of patients treated by transcatheter mitral valve repair: A systematic review and meta-analysis
Conclusion: AF may be related with worse outcomes in patients undergoing MC implantation, including long-term mortality, major bleeding, and rehospitalization. AF should be taken into account when referring a patient for MC treatment.
Source: Medicine - October 2, 2020 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Long ‐term risk of heart failure and mortality following mitral valve surgery in patients with and without right ventricular pacemaker
ConclusionsPostoperative implantation of a permanent RV pacemaker does not alter the long ‐term risks of HF and mortality following mitral valve surgery.
Source: Journal of Cardiac Surgery - September 27, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Charlotte Andersson, Morten Schou, Gunnar H. Gislason, Lars K øber, Christian Torp‐Pedersen, Kevin M. Monahan Tags: ORIGINAL ARTICLE Source Type: research

Anticoagulation following mitral valve repair
ConclusionsOur analysis showed that postoperative warfarin use was associated with an overall reduced composite of bleeding and thromboembolic incidents and superior long ‐term survival. These findings suggest that anticoagulation with warfarin following mitral valve repair may be a safe and effective means for avoiding postoperative complications and that a large prospective randomized clinical trial is warranted.
Source: Journal of Cardiac Surgery - August 1, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Tessa M. F. Watt, Shannon L. Murray, Alexander A. Brescia, David A. Burn, Alexander Wisniewski, Shazli P. Khan, Matthew A. Romano, Steven F. Bolling, The Michigan Mitral Research Group (MMRG) Tags: ORIGINAL ARTICLE Source Type: research

Less Invasive Mitral Surgery versus Conventional Sternotomy Stratified by Mitral Pathology.
CONCLUSIONS: LIMS was associated with higher mitral repair rates, and lower morbidity. Further studies regarding the impact of surgeon volume on choice of operative approach are necessary. PMID: 32717233 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - July 23, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Nissen AP, Miller CC, Thourani VH, Woo YJ, Gammie JS, Ailawadi G, Nguyen TC Tags: Ann Thorac Surg Source Type: research

Impact of Left Atrial Appendage Exclusion on Short Term Outcomes In Isolated Coronary Artery Bypass Graft Surgery.
Conclusions: LAA exclusion during isolated CABG in patients with AF is associated with a higher rate of 30-day readmission. Post-operative measures to mitigate the loss of the hormonal and hemodynamic effects of the LAA may increase the therapeutic benefit of this procedure. PMID: 32489114 [PubMed - as supplied by publisher]
Source: Circulation - June 2, 2020 Category: Cardiology Authors: Mahmood E, Matyal R, Mahmood F, Xu X, Sharkey A, Chaudhary O, Karani S, Khabbaz KR Tags: Circulation Source Type: research

Long-term echocardiographic evaluation of asymptomatic patients undergoing minimally invasive valve repair for severe primary mitral regurgitation.
CONCLUSIONS: Minimally invasive mitral valve repair is a safe and efficient method of correction in asymptomatic patients. The intervention should be performed regardless of ventricular and atrial dimensions. PMID: 32267134 [PubMed - as supplied by publisher]
Source: Polish Heart Journal - April 7, 2020 Category: Cardiology Authors: Gerber W, Sanetra K, Drzewiecka-Gerber A, Jankowska-Sanetra J, Bochenek A, Zembala M, Cisowski M Tags: Kardiol Pol Source Type: research

Impact of left atrial diameter on outcome in patients undergoing edge ‐to‐edge mitral valve repair: results from the German TRAnscatheter Mitral valve Interventions (TRAMI) registry
ConclusionLeft atrial enlargement is a strong and independent predictor of adverse long ‐term outcome after transcatheter mitral valve repair. Further study is warranted to examine whether timely intervention may have the potential to modify outcome.
Source: European Journal of Heart Failure - April 3, 2020 Category: Cardiology Authors: Christos Iliadis, Stephan Baldus, Daniel Kalbacher, Peter Boekstegers, Wolfgang Schillinger, Taoufik Ouarrak, Ralf Zahn, Christian Butter, Christine S. Zuern, Ralph Stephan Bardeleben, Jochen Senges, Raffi Bekeredjian, Holger Eggebrecht, Roma Tags: Research Article Source Type: research

Uncommon Complication From Left Atrial Appendage Occluder (Laao)
We report a case with uncommon late complication of this device causing erosion of the left ventricle, which open heart operation was carried out to repair the defect.
Source: Surgical Practice - March 31, 2020 Category: Surgery Authors: Lau Kwun Wang Ambrose, Chum Hoi ‐Leung Him, Cheung Hung‐leong Tags: ORIGINAL ARTICLE Source Type: research

Risk of stroke, atrial fibrillation, and major bleeding after mitral valve repair: the jury is still out.
Authors: Giacoppo D, Tarantini G PMID: 32200344 [PubMed - as supplied by publisher]
Source: EuroIntervention - March 23, 2020 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research

Abbott Wins Approval for CATALYST Trial for At-Risk Stroke Patients
This study is an extremely important step in assessing the Amplatzer Amulet as an effective non-prescription drug alternative for patients with AFib who are at an increased risk for ischemic stroke." In an email sent to MD+DI, Abbott wrote, “We already have an Amulet IDE trial underway that is intended to support our submission for approval in the U.S. for Amplatzer Amulet. The newly announced CATALYST trial will support our submission for an expanded indication for Amulet as a safe and effective alternative to NOAC drugs for patients with atrial fibrillation and at risk of stroke.” Abbo...
Source: MDDI - February 3, 2020 Category: Medical Devices Authors: Omar Ford Tags: Cardiovascular Regulatory and Compliance Source Type: news

Comparison of expected and observed outcomes for septal myectomy in hypertrophic obstructive cardiomyopathy
ConclusionsSeptal myectomy, performed in a tertiary referral center, had a 30-day mortality rate of 0% and low morbidity rate. There was no difference between observed myectomy mortality and STS Calculator predicted risk for AVR and MV repair. It is possible that a larger sample could reveal lower mortality than STS prediction.
Source: American Heart Journal - December 19, 2019 Category: Cardiology Source Type: research

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