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Condition: Stroke
Procedure: Heart Valve Surgery

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Total 3059 results found since Jan 2013.

Cerebral Embolic Protection Devices in Transcatheter Aortic Valve Replacement —Effective in Stroke Prevention?
Transcatheter aortic valve replacement (TAVR) has become the mainstay of treatment for severe symptomatic aortic stenosis. Despite advances in device technology and procedural techniques, periprocedural stroke remains a severe complication of TAVR, affecting 2% of patients. The embolization of calcific debris from the degenerated aortic valve and atherosclerotic plaque from the aorta, both of which are manipulated during TAVR, is the likely mechanism of periprocedural stroke. Accordingly, cerebral embolic protection devices (EPDs) have been designed to prevent stroke by sequestering embolic debris during TAVR.
Source: JAMA Internal Medicine - February 24, 2020 Category: Internal Medicine Source Type: research

Anticoagulation Resumption in a Patient With Mechanical Heart Valves, Antithrombin Deficiency, and Hemorrhagic Transformation Following Thrombectomy After Ischemic Stroke
This study is the first report of administering argatroban and titrating to its appropriate dose in the patient with valve thrombosis, antithrombin deficiency, and HT after mechanical thrombectomy for acute ischemic stroke. Notably, the fluctuations argatroban brings to the coagulation test results might not be interpreted as increased bleeding risk. This case also suggested that the reported timing (day 6 to day 14 after hemorrhage) of anticoagulant resumption in primary intracerebral hemorrhage with mechanical valves might be late for some patients with HT.
Source: Frontiers in Pharmacology - December 16, 2020 Category: Drugs & Pharmacology Source Type: research

Association Of Stroke With Pattern Of Aortic Leaflet And Left Ventricular Outflow Tract Calcifications
Introduction: Stroke is a feared complication of transcatheter aortic valve replacement (TAVR) used for treatment of severe aortic stenosis. The risk of stroke has been associated with leaflet calcification burden. We aimed to investigate whether a specific pattern of aortic leaflet and left ventricular outflow tract (LVOT) calcification is associated with stroke risk.
Source: Journal of Cardiovascular Computed Tomography - July 1, 2021 Category: Radiology Authors: D. Brito, M. Shotwell, P. Agrawal, S. Patibandla, M. Kadiyala, Y. Hamirani, R. Daggubati, B. Raybuck, A. Kawsara, I. Zeb Source Type: research

Successful Endovascular Stroke Rescue With Retrieval of an Embolized Calcium Fragment After Transcatheter Aortic Valve Replacement Images and Case Reports in Interventional Cardiology
Source: Circulation: Cardiovascular Interventions - February 18, 2014 Category: Cardiology Authors: Fassa, A.-A., Mazighi, M., Himbert, D., Deschamps, L., Ducrocq, G., Cheong, A. P., Depoix, J.-P., Dilly, M.-P., Alkhoder, S., Mourvillier, B., Vahanian, A. Tags: Catheter-based coronary and valvular interventions: other, Embolic stroke, Emergency treatment of Stroke Images and Case Reports in Interventional Cardiology Source Type: research

Cardiac Valve Strands in Ischemic Stroke: Strand Effects and Outcomes of Medical or Surgical Intervention (P4.233)
CONCLUSIONS:At present, there is no consensus regarding appropriate therapy for prevention of recurrent strokes in the setting of valve strands. Based on this case series, four patients continued to have ischemic events on aspirin alone, while patients who started warfarin or later underwent surgery did not have any recurrent strokes at one to two year follow-up. As demonstrated, valve strands can also recur despite removal. The long-term therapeutic intervention remains to be determined. Disclosure: Dr. Chu has nothing to disclose. Dr. Fabian has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Chu, J., Fabian, R. Tags: Cerebrovascular Disease and Interventional Neurology: Cardiac Source Type: research

Slope in preload recruitable stroke work relationship predicts survival after left ventriculoplasty and mitral repair in patients with idiopathic cardiomyopathy.
CONCLUSIONS: Mw, the slope in the PRSW relationship, may predict survival after LVP and MVP in patients with idiopathic DCM. PMID: 24954287 [PubMed - as supplied by publisher]
Source: Journal of Cardiology - June 18, 2014 Category: Cardiology Authors: Shingu Y, Kubota S, Wakasa S, Ooka T, Kato H, Tachibana T, Matsui Y Tags: J Cardiol Source Type: research

Stroke and thrombus formation appending to the MitraClip: what is the appropriate anticoagulation regimen?
Authors: Hamm K, Barth S, Diegeler A, Kerber S Abstract Percutaneous mitral valve repair with the MitraClip system (Abbot Vascular, USA) is a promising technique for the non-surgical treatment of mitral regurgitation in special situations. The case is reported of a 72-year-old patient with history of atrial fibrillation and a severely impaired left ventricular function who underwent successful MitraClip implantation because of functional mitral regurgitation grade 3. The patient's post-interventional course was complicated three weeks later by a cardioembolic stroke due to thrombus formation on the MitraClip, despi...
Source: Journal of Heart Valve Disease - December 1, 2014 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Survival by stroke volume index in patients with low-gradient normal EF severe aortic stenosis
Conclusions Lower SVI is incrementally associated with mortality in LG severe AS with preserved EF. These findings have implications for classification of AS severity, identification of high-risk groups and subsequent management.
Source: Heart - December 12, 2014 Category: Cardiology Authors: Eleid, M. F., Sorajja, P., Michelena, H. I., Malouf, J. F., Scott, C. G., Pellikka, P. A. Tags: Editor's choice, Drugs: cardiovascular system, Echocardiography, Aortic valve disease, Clinical diagnostic tests, Epidemiology Valvular heart disease Source Type: research

Agreement between stroke volume measured by oesophageal Doppler and uncalibrated pulse contour analysis during fluid loads in severe aortic stenosis
Abstract The purpose of this analysis was to study agreement and trending of stroke volume measured by oesophageal Doppler and 3rd generation Vigileo during fluid loads in patients with severe aortic stenosis. Observational study in 32 patients (30 analyzed) scheduled for aortic valve replacement due to severe aortic stenosis. After induction of anesthesia and before start of surgery, hemodynamic registrations for 1 min were obtained before and after a fluid load. Agreement between stroke volume measured by oesophageal Doppler (SVOD) and Vigileo (SVVig) was evaluated in Bland–Altman plot and trending in four-qu...
Source: Journal of Clinical Monitoring and Computing - January 31, 2015 Category: Information Technology Source Type: research

Stroke is not a treatment dilemma for early valve surgery in active infective endocarditis.
CONCLUSION: Surgery for AIE with cerebral septic embolisms can be performed safely, with good early and mid-term follow-up results. When urgent or emergent surgery for AIE is needed, neurologic complications should not be a reason for delay. PMID: 25799711 [PubMed - in process]
Source: Journal of Heart Valve Disease - March 25, 2015 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Knowledge Regarding Oral Anticoagulation Therapy among Patients with Stroke and Those at High Risk of Thromboembolic Events (P6.241)
Conclusion- Patient’s knowledge about OAT was suboptimal. The findings support the need for educational interventions to improve the knowledge regarding oral anticoagulation therapy, and thereby achieve an appropriate and safe secondary prevention of stroke.Disclosure: Dr. Bhatia has nothing to disclose. Dr. Alphonsa has nothing to disclose. Dr. Sharma has nothing to disclose. Dr. Sharma has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Bhatia, R., Alphonsa, A., Sharma, K., Sharma, G. Tags: Cerebrovascular Disease and Interventional Neurology: Thrombolysis Complications Source Type: research

Pharmacological Management Strategies for Stroke Prevention Following Transcatheter Aortic Valve Replacement: A Systematic Review
The most appropriate pharmacological treatment for stroke prevention after transcatheter aortic valve replacement (TAVR) is unclear. We performed a systematic review of randomized controlled trials (RCTs) and observational studies examining the effect of various pharmacological treatment regimens on rates of stroke, bleeding, and death after TAVR.
Source: International Journal of Cardiology - April 30, 2015 Category: Cardiology Authors: Lee H. Sterling, Sarah B. Windle, Kristian B. Filion, Mark J. Eisenberg Tags: Review Source Type: research

Neurological Inȷury in Intermediate-Risk Transcatheter Aortic Valve Implantation Interventional Cardiology
ConclusionsObjectively measured subclinical neurological injuries remain a concern in intermediate‐risk patients undergoing TAVI and are likely to manifest with early neurocognitive changes.Clinical Trial RegistrationURL: http://www.anzctr.org.au. Australian & New Zealand Clinical Trials Registry: ACTRN12613000083796.
Source: JAHA:Journal of the American Heart Association - November 14, 2016 Category: Cardiology Authors: Fanning, J. P., Wesley, A. J., Walters, D. L., Eeles, E. M., Barnett, A. G., Platts, D. G., Clarke, A. J., Wong, A. A., Strugnell, W. E., O'Sullivan, C., Tronstad, O., Fraser, J. F. Tags: Aortic Valve Replacement/Transcatheter Aortic Valve Implantation, Cerebrovascular Disease/Stroke, Cognitive Impairment Original Research Source Type: research

A Patient with Quadricuspid Aortic Valve and Ischemic Stroke.
Authors: Krisper M, Köhncke C, Escher F, Morris DA, Tschöpe C, Pieske B Abstract Quadricuspid aortic valve (QAV) is a rare congenital cardiac defect. Aortic regurgitation is the predominant hemodynamically relevant abnormality in patients with QAV, and the main reason for patients requiring valve surgery. Calcific valve disease of the left heart valves is classified as 'low embolic risk' according to current guidelines. However, it remains an important risk factor of cardiovascular events, including ischemic stroke. A 71-year-old woman presented with new-onset aphasia and hemiparesis of the right side of her body...
Source: Journal of Heart Valve Disease - December 25, 2016 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Measuring and mitigating stroke in transcatheter aortic valve implantation: Long roads to the easy answers
Transcatheter aortic valve implantation (TAVI) has rapidly displayed its utility in the treatment of aortic valve disease. While presenting a lesser procedural morbidity and mortality risk, as compared with surgical aortic valve replacement (SAVR), early trials reported higher rates of stroke.1,2 To mitigate this complication, cerebral embolic protection (CEP) devices were developed for use in TAVI but there has been limited penetrance into the market. Among the reasons for this are their novelty, relatively low rates of clinically relevant stroke, added complexity of their deployment, cost, and uncertainty of their benefit.
Source: The Journal of Thoracic and Cardiovascular Surgery - February 12, 2017 Category: Cardiovascular & Thoracic Surgery Authors: John Bozinovski Tags: Editorial commentary Source Type: research