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What It Will Take to Avoid a Tripledemic This Winter
Over the coming months, more than 100,000 Americans will likely die, mostly unnecessarily, from respiratory infections. Yes, that is the reality we are now facing this fall and winter—and likely every fall and winter for the foreseeable future. Unless we act. Between flu, COVID-19, and RSV, we are likely looking at a very large number of Americans getting sick, ending up in the hospital, and dying. Most of these Americans will be our most vulnerable: older Americans, the youngest children, and those with chronic diseases. And that number of 100,000 may be an underestimate, given that many of these infections go undet...
Source: TIME: Health - September 22, 2023 Category: Consumer Health News Authors: Dr. Ashish K. Jha Tags: Uncategorized COVID-19 freelance Source Type: news
Post-Stroke Lateropulsion: Resolution and Function After Discharge From Inpatient Rehabilitation - A Cohort Study
CONCLUSIONS: Lateropulsion can continue to resolve after discharge from inpatient rehabilitation. Larger cohort studies are needed to further explore associations between persistent lateropulsion and long-term outcomes.PMID:37736404 | PMC:PMC10510537 | DOI:10.3138/ptc-2021-0078
Source: Physiotherapy Canada - September 22, 2023 Category: Physiotherapy Authors: Jessica Nolan Erin Godecke Katrina Spilsbury Barbara Singer Source Type: research
PPP1R12C Promotes Atrial Hypocontractility in Atrial Fibrillation
CONCLUSIONS: Patients with AF exhibit increased levels of PPP1R12C protein compared with controls. PPP1R12C overexpression in mice increases PP1c targeting to MLC2a and causes MLC2a dephosphorylation, which reduces atrial contractility and increases AF inducibility. These findings suggest that PP1 regulation of sarcomere function at MLC2a is a key determinant of atrial contractility in AF.PMID:37737016 | DOI:10.1161/CIRCRESAHA.123.322516
Source: Circulation Research - September 22, 2023 Category: Cardiology Authors: Srikanth Perike Francisco J Gonzalez-Gonzalez Issam Abu-Taha Frederick W Damen Laurin M Hanft Ken S Lizama Anahita Aboonabi Andrielle E Capote Yuriana Aguilar-Sanchez Benjamin Levin Zhenbo Han Arvind Sridhar Jacob Grand Jody Martin Joseph G Akar Chad M Wa Source Type: research
The prevalence and prognosis of asymptomatic intracranial atherosclerosis in a community-based population: Results based on high-resolution magnetic resonance imaging
CONCLUSIONS: We found that ICAD detected using HR-MRI increases the long-term risk of a first-ever ischemic stroke in a stroke-free population, suggesting that the current primary prevention protocol of stroke awaits further optimization.PMID:37738517 | DOI:10.1111/ene.16057
Source: Atherosclerosis - September 22, 2023 Category: Cardiology Authors: Shengde Li Mingyu Tang Dingding Zhang Fei Han Lixin Zhou Ming Yao Mingli Li Liying Cui Shuyang Zhang Bin Peng Zhengyu Jin Yicheng Zhu Jun Ni Source Type: research
PPP1R12C Promotes Atrial Hypocontractility in Atrial Fibrillation
CONCLUSIONS: Patients with AF exhibit increased levels of PPP1R12C protein compared with controls. PPP1R12C overexpression in mice increases PP1c targeting to MLC2a and causes MLC2a dephosphorylation, which reduces atrial contractility and increases AF inducibility. These findings suggest that PP1 regulation of sarcomere function at MLC2a is a key determinant of atrial contractility in AF.PMID:37737016 | DOI:10.1161/CIRCRESAHA.123.322516
Source: Cell Research - September 22, 2023 Category: Cytology Authors: Srikanth Perike Francisco J Gonzalez-Gonzalez Issam Abu-Taha Frederick W Damen Laurin M Hanft Ken S Lizama Anahita Aboonabi Andrielle E Capote Yuriana Aguilar-Sanchez Benjamin Levin Zhenbo Han Arvind Sridhar Jacob Grand Jody Martin Joseph G Akar Chad M Wa Source Type: research
Scoping Review on Brain-Computer Interface-Controlled Electrical Stimulation Interventions for Upper Limb Rehabilitation in Adults: A Look at Participants, Interventions, and Technology
CONCLUSIONS: Future BCI-ES interventional studies could address this gap. Additionally, standardization of device and rehabilitation modalities, and study-appropriate involvement with therapists, can be considered to advance this intervention towards clinical implementation.PMID:37736411 | PMC:PMC10510539 | DOI:10.3138/ptc-2021-0074
Source: Physiotherapy Canada - September 22, 2023 Category: Physiotherapy Authors: Lazar I Jovanovic Hope Jervis Rademeyer Maureen Pakosh Kristin E Musselman Milos R Popovic Cesar Marquez-Chin Source Type: research
Perceived performance of activities of daily living by stroke patients: key in decision to call EMS and outcomes
ConclusionPerception of unimpaired performance of ADL is a crucial barrier to appropriate help-seeking behavior after acute stroke, leading to undertreatment and less improvement in clinical symptoms. Thus, beyond improving the public’s knowledge of stroke symptoms, future public education campaigns should focus on the need for calling the EMS in case of stroke symptoms even if daily activities do not seem to be severely impaired.
Source: Frontiers in Neurology - September 22, 2023 Category: Neurology Source Type: research
Pulse rate variability predicted cardiovascular disease in sleep disordered breathing: The Guangdong sleep health study
CONCLUSIONS: PRV parameters may be specific predictors for CVD in SDB. PNN50 was a potent biomarker for CVD risk in the elderly with SDB, event without traditional CVD risk factors.PMID:37734671 | DOI:10.1016/j.rmed.2023.107408
Source: Respiratory Care - September 21, 2023 Category: Respiratory Medicine Authors: Miaochan Lao Qiong Ou Guangliang Shan Murui Zheng Guo Pei Yanxia Xu Longlong Wang Jiaoying Tan Bin Lu Source Type: research
Impact of prior bariatric surgery on outcomes of hospitalized patients with systemic lupus erythematosus: a propensity score-matched analysis of the U.S. nationwide inpatient sample
CONCLUSIONS: Prior bariatric surgery is associated with favorable in-hospital outcomes in hospitalized patients with SLE and decreased likelihood for several SLE-related complications.PMID:37735043 | DOI:10.1016/j.soard.2023.06.006
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - September 21, 2023 Category: Surgery Authors: Po-Chun Wang Kung-Chan Ho Wen-Ching Ko Wei-Ning Lin Source Type: research
Fatigue Experiences in People With Stroke
CONCLUSIONS: Fatigue experiences vary over time and have both physical and mental aspects to them.CLINICAL RELEVANCE TO REHABILITATION NURSING: Nurses may consider providing a quiet environment for physical rest, which may allow the brain to not be distracted by multiple stimuli.PMID:37733016 | DOI:10.1097/RNJ.0000000000000431
Source: Rehabilitation Nursing - September 21, 2023 Category: Rehabilitation Authors: Rozina Bhimani Jiayue Xiong Lisa Anderson Source Type: research
Oral Anticoagulation Use and Left Atrial Appendage Occlusion in LAAOS III
CONCLUSIONS: The benefit of LAA occlusion was consistent whether patients were receiving OACs or not. LAA occlusion provides thromboembolism reduction in patients independent of OAC use.PMID:37732457 | DOI:10.1161/CIRCULATIONAHA.122.060315
Source: Circulation - September 21, 2023 Category: Cardiology Authors: Stuart J Connolly Jeff S Healey Emilie P Belley-Cote Kumar Balasubramanian Domenico Paparella Katheryn Brady Wilko Reents Bernhard C Danner P J Devereaux Mukul Sharma Chinthanie Ramasundarahettige Salim Yusuf Richard P Whitlock Source Type: research
Current practice of outpatient rehabilitation services in patients with mobility-impaired paralysis due to stroke or spinal cord injury: a qualitative interview study in Germany
CONCLUSION: Areas of improvement identified focused on: setting rehabilitation goals towards participation, training therapists on evidence-based treatments and shared decision-making, updating the outpatient service catalogue, and implementing coordination actions. Implementation of these recommendations should be evaluated.PMID:37732606 | DOI:10.1080/09638288.2023.2259301
Source: Disability and Rehabilitation - September 21, 2023 Category: Rehabilitation Authors: Tiziana Daniel Tamara Spingler Andreas Hug Norbert Weidner Michel Wensing Charlotte Ullrich Source Type: research
The effects of cycling on walking outcomes in adults with stroke: a systematic review
CONCLUSION: Considerable heterogeneity was observed across cycling protocols with respect to intensity, frequency, exercise duration and protocol duration. However, none of the studies reported declines in walking outcomes and improvements were measured in the absence of task-specific gait training. Cycling interventions employing moderate- to high-intensity aerobic training and 24 sessions or more may be optimal in improving gait velocity and walking capacity.PMID:37732513 | DOI:10.1080/10749357.2023.2259167
Source: Topics in Stroke Rehabilitation - September 21, 2023 Category: Neurology Authors: Madeeha Khan Logan M Maag Mary Pat Harnegie Susan M Linder Source Type: research
Association between electronic nicotine delivery systems use and risk of stroke: a meta-analysis of 1,024,401 participants
CONCLUSIONS: The ENDS usage appears to be associated with a higher risk of stroke compared to non-use, whereas there was no association between former ENDS use and the risk of stroke.PMID:37732043 | PMC:PMC10507757 | DOI:10.5114/aoms/171473
Source: Archives of Medical Science - September 21, 2023 Category: Biomedical Science Authors: Kamal Awad Maged Mohammed Seth S Martin Maciej Banach Source Type: research
Analysis of 622 paediatric hospitalisations due to arterial ischaemic stroke in Poland - National Health Fund registry-based study from 2011 to 2020
CONCLUSIONS: Data from the NHF registry proved that AIS occurs more often in boys than in girls and is more common in adolescents (15-18 years) than in younger children.PMID:37732035 | PMC:PMC10507785 | DOI:10.5114/aoms/151684
Source: Archives of Medical Science - September 21, 2023 Category: Biomedical Science Authors: Beata Sarecka-Hujar Micha ł Maluchnik Jaros ław Bartosiński Karol Tarkowski Agnieszka Ch łoń-Domińczak Ilona Kopyta Dorota Raczkiewicz Source Type: research
