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Condition: Vasculitis

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Total 771 results found since Jan 2013.

Acute ischemic stroke in a young female: a novel presentation of anti-GAD autoimmunity (P3.272)
Conclusions:Restricted diffusion, seen typically in ischemia, indicates cytotoxic oedema and irreversible cell damage. In this patient, we postulate a mechanism of severe CNS inflammation with cellular toxicity and small vessel vasculitis. Anti-GAD autoimmunity should be considered in young patients presenting with stroke-like episodes, particularly when accompanied by positive phenomenon.Disclosure: Dr. Neo has nothing to disclose. Dr. Lee has nothing to disclose. Dr. Lee has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Neo, X. S., Lee, K. E., Lee, R. Tags: Cerebrovascular Disease Case Reports II Source Type: research

Convexal subarachnoid hemorrhage and acute ischemic stroke: a border zone matter?
ConclusionsWe proposed the embolism or hemodynamic changes of the border zone arterioles as a unifying pathogenetic hypothesis of coexisting c-SAH and AIS.
Source: Neurological Sciences - April 1, 2019 Category: Neurology Source Type: research

Herpes simplex virus 2 vasculitis as cause of ischemic stroke in a young immunocompromised patient
We report a case of a young woman with a left middle cerebral artery (MCA) ischemic stroke. The patient had history of HIV-1 infection, with periods of therapeutic non-compliance. Initial computed tomography (CT) imaging studies showed stenosis of the M1 segment of the left MCA, and magnetic resonance imaging (MRI) confirmed infarction of the MCA territory. Serial transcranial Doppler ultrasound revealed progressive occlusion of the MCA and stenosis of the left anterior cerebral artery. Systemic investigation for other causes of stroke was normal. Lumbar puncture revealed a mildly inflammatory cerebrospinal fluid, and HSV-...
Source: Journal of NeuroVirology - August 23, 2020 Category: Neurology Source Type: research

Rare stroke mechanisms in 4154 consecutive patients: causes, predictors, treatment, and outcomes
CONCLUSIONS: RMS occurred in 5.3% of a large population of consecutive AISs and are most frequently related to medical interventions, cancer, and vasculitis. RMS patients have less traditional risk factors but more systemic comorbidities, hemorrhagic transformations, recurrences, and a worse long-term outcome. Identification of RMS has direct implications for early treatment and long-term outcome.PMID:35994133 | DOI:10.1007/s10072-022-06344-w
Source: Cancer Control - August 22, 2022 Category: Cancer & Oncology Authors: Alex Vicino Gaia Sirimarco Ashraf Eskandari Dimitris Lambrou Philippe Maeder Vincent Dunet Patrik Michel Source Type: research

Zoster-associated Prothrombotic Plasma Exosomes and Increased Stroke Risk
J Infect Dis. 2022 Oct 6:jiac405. doi: 10.1093/infdis/jiac405. Online ahead of print.ABSTRACTHerpes zoster (HZ, shingles) caused by varicella zoster virus (VZV) reactivation increases stroke risk for up to one-year post-HZ. The underlying mechanisms are unclear, however, the development of stroke distant from the site of zoster (e.g. thoracic, lumbar, sacral) that can occur months after resolution of rash points to a long-lasting, virus-induced soluble factor(s) that can trigger thrombosis and/or vasculitis. Herein, we investigated the content and contributions of circulating plasma exosomes from HZ and non-HZ patient samp...
Source: Herpes - October 6, 2022 Category: Infectious Diseases Authors: Andrew N Bubak Christina Coughlan Janelle Posey Anthony J Saviola Christy S Niemeyer Serena W R Lewis Sara Bustos Lopez Adriana Solano Stephen K Tyring Cassidy Delaney Keith B Neeves Ravi Mahalingam Kirk C Hansen Maria A Nagel Source Type: research

HIV-associated multiple intracranial aneurysms and stroke in an adult patient: successful treatment with a combination of glucocorticoid and antiviral agents
AbstractA 35-year-old Iranian man with an 18-year history of human immunodeficiency virus (HIV) infection developed sudden left-sided hemiparesis and mild dysarthria. Based on laboratory results, brain and neck computerized tomography angiography (CTA), echocardiography, hypercoagulability tests, and vasculitis tests, the patient was diagnosed with a stroke with multiple intracranial aneurysms secondary to HIV. Cerebral aneurysms and stroke are uncommon in HIV-infected patients, and the aneurysms ’ exact cause and risk factors are unknown. There is currently no effective regimen or definitive treatment for HIV-associated...
Source: Journal of NeuroVirology - December 13, 2022 Category: Neurology Source Type: research

Thrombolysis for acute stroke in patients with vasculitis: Case report and literature discussion
We present a case of ICH after tPA administration in a patient with known Churg–Strauss Syndrome (CSS) and discuss the implications of thrombolysis in patients with vasculitis.
Source: Clinical Neurology and Neurosurgery - June 20, 2012 Category: Neurosurgery Authors: Pooia Fattahi, Faheem Sheriff, Nandakumar S. Narayanan, David M. Greer, Joseph Schindler Tags: Case Reports Source Type: research

CNS vasculitis and stroke in neonatal lupus erythematosus: A case report and review of literature.
We describe a 2-months-old girl who presented with acute ischemic stroke secondary to central nervous system vasculitis without any cardiac, cutaneous or hematological manifestations. The mother was pauci-symptomatic with raised anti-Ro autoantibody titers; the baby was positive for autoantibodies against Ro-antigen. Angiography confirmed vasculitis in cerebral vasculature. Our case highlights that neonatal lupus erythematosus can present with isolated nervous system manifestations and the vascular damage can be permanent in the form of vasculitis. Early recognition will help pediatricians identify such possible permanent ...
Source: European Journal of Paediatric Neurology - January 25, 2014 Category: Neurology Authors: Saini AG, Sankhyan N, Bhattad S, Vyas S, Saikia B, Singhi P Tags: Eur J Paediatr Neurol Source Type: research

A Rare Association between Ulcerative Colitis and Bilateral Thalamic Stroke (P6.270)
CONCLUSIONS:Cerebral sinus and vein thrombosis is a serious and often fatal complication of idiopathic inflammatory bowel disease if undiagnosed. It should be considered in any patient with little or no known vascular risk factors presenting with a severe headache and other focal or diffuse neurological signs.Disclosure: Dr. Misthal has nothing to disclose. Dr. Haitham has nothing to disclose. Dr. Bashir has nothing to disclose. Dr. Hussain has nothing to disclose. Dr. Moussavi has nothing to disclose. Dr. Kirmani has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Misthal, S., Haitham, D., Bashir, A., Hussain, M., Moussavi, M., Kirmani, J. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Patterns of intracranial vessel wall changes in relation to ischemic infarcts
Conclusion: Our results suggest that the combination of intracranial vessel wall abnormalities and infarct type is related to different stroke etiologies.
Source: Neurology - October 6, 2014 Category: Neurology Authors: Dieleman, N., van der Kolk, A. G., van Veluw, S. J., Frijns, C. J. M., Harteveld, A. A., Luijten, P. R., Hendrikse, J. Tags: Stroke in young adults, MRI, Vasculitis, All Cerebrovascular disease/Stroke ARTICLE Source Type: research

The Great Imitator—Still Today! A Case of Meningovascular Syphilis Affecting the Posterior Circulation
We describe clinical features and imaging studies of a 50-year-old patient with Parinaud syndrome and a syphilitic dorsal midbrain infarction. Brain magnetic resonance imaging indicated vasculitis of the posterior circulation. The diagnosis of meningovascular syphilis was established by serum and cerebrospinal fluid examinations. Although rare, because of the high impact on treatment, clinicians should always be aware of meningovascular syphilis in the differential diagnosis of stroke, particularly in young and male patients with cryptogenic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - October 2, 2014 Category: Neurology Authors: Jochen Bäuerle, Anna Zitzmann, Karl Egger, Stephan Meckel, Cornelius Weiller, Andreas Harloff Tags: Case Report Source Type: research

Varicella-Zoster Vasculitis Presenting with Cerebellar Hemorrhage
Varicella zoster virus (VZV) is known as one of the rare, but important, causes of both ischemic and hemorrhagic stroke. Most previously reported VZV-related hemorrhagic stroke and cerebral vasculitis are associated with anterior circulation because VZV spreads from trigeminal ganglia to the anterior circulation of Willis. The present study presents a patient with cerebellar hemorrhage, who was diagnosed with VZV encephalitis and vasculitis of the posterior inferior cerebellar artery.
Source: Journal of Stroke and Cerebrovascular Diseases - March 31, 2015 Category: Neurology Authors: Kazuya Matsuo, Yoichi Uozumi, Hirohito Miyamoto, Shotaro Tatsumi, Eiji Kohmura Tags: Case Report Source Type: research

Erdheim–Chester Disease: An Unusual Cause of Intracranial Vasculitis and Progressive Leukoencephalopathy
We report the case of a 64-year-old man who presented with an acute ischemic stroke associated with a moderate leukoencephalopathy and intracranial arteries stenosis. Four years later, he developed movement disorders with dysarthria and cognitive impairment. Neuroradiological findings demonstrated a rapidly progressive and diffuse leukoencephalopathy associated with brain atrophy and infiltration of the intracranial vertebral artery wall.
Source: Journal of Stroke and Cerebrovascular Diseases - March 17, 2016 Category: Neurology Authors: Sharmila Sagnier, Sabrina Debruxelles, Sébastien Lepreux, Igor Sibon Tags: Case Report Source Type: research

Stroke in Ehlers-Danlos Syndrome kyphoscoliotic type (EDSVIA): dissection or vasculitis?
A 13-year-old girl affected with the kyphoscoliotic type of Ehlers-Danlos syndrome (EDS VIA) suffered a stroke of the right middle cerebral artery. MR angiography and arteriography were not indicative of arterial dissection but of cerebral vasculitis. Immunosuppressive treatment resulted in clinical improvement. Six weeks after the stroke she suddenly died from hemorrhagic shock due to spontaneous aortic artery ruptures. Altered collagen function in EDS type VIa may differently affect cerebral and non-cerebral arteries.
Source: Pediatric Neurology - May 29, 2017 Category: Neurology Authors: Annegret Quade, Martin Wiesmann, Joachim Weis, Ingo Kurth, Houman Jalaie, Marianne Rohrbach, Martin H äusler Tags: Short Communication Source Type: research

Neuro-Behcet's Disease Presenting as a Young Stroke.
Authors: Biniwale N, Kibe R, Biniwale A Abstract Neuro-Behcet's disease (NBD) is a rare neurological manifestation of the systemic small vessel vasculitis called Behcet's disease. It can present in various ways with predilection for the brain stem, thalamo- hypothalamic regions, cerebellum and basal ganglia. In this case, we describe a case of young stroke that was later attributed to NBD. PMID: 28598056 [PubMed - in process]
Source: Journal of the Association of Physicians of India - June 11, 2017 Category: General Medicine Tags: J Assoc Physicians India Source Type: research