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Condition: Chronic Pain
Therapy: Pain Management

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Total 682 results found since Jan 2013.

Curing hemoglobinopathies: challenges and advances of conventional and new gene therapy approaches.
Inherited hemoglobin disorders, including beta-thalassemia (BT) and sickle-cell disease (SCD) are the most common monogenic diseases worldwide, with a global carrier frequency of over 5%. With migration they are becoming more common worldwide, making their management and care an increasing concern for health care systems.BT is characterized by an imbalance in the α/β-globin chain ratio, ineffective erythropoiesis, chronic hemolytic anemia, and compensatory haemopoietic expansion. Globally, there are over 25,000 births each year with transfusion-dependent thalassemia (TDT). The current available treatment f...
Source: Mediterranean Journal of Hematology and Infectious Diseases - October 30, 2019 Category: Hematology Source Type: research

Axillary Peripheral Nerve Stimulation for Chronic Shoulder Pain: A Retrospective Case Series
ConclusionsThis retrospective case series provides level IV evidence supporting the use of axillary PNS therapy for the management of chronic shoulder pain. Additional, higher ‐level studies are required to further support its use.
Source: Neuromodulation: Technology at the Neural Interface - January 12, 2020 Category: Biotechnology Authors: John Taylor Mansfield, Mehul J. Desai Tags: Case Series Source Type: research

What to Expect in Neuromodulation This Year
The spinal cord stimulation (SCS) market growth should improve in 2020 as leaders in the space launch new products and benefit from recent acquisitions and invest in potential indication expansions, according to Needham & Co.'s Mike Matson. The medtech analyst published a report Monday sharing his takeaways from the North American Neuromodulation Society (NANS) meeting in Las Vegas, NV over the weekend. Matson noted that SCS device market growth should continue to improve in 2020 and beyond, thanks to a number of factors. The analyst estimates that SCS currently represents about $2.5 billion, wh...
Source: MDDI - January 27, 2020 Category: Medical Devices Authors: Amanda Pedersen Tags: Business Source Type: news

What Are Some Risk Factors for Cerebral Palsy?
Discussion The term, cerebral palsy, or CP has gone through many iterations with the first description in 1861 by W.J. Little who described it as “The condition of spastic rigidity of the limbs of newborn children.” The most recent definition is from Rosenbaun et al. in 2007 which states it is “a group of permanent disorders of the development of movement and posture, causing activity limitation, that are attributed to non-progressive disturbances that occurred in the developing fetal or infant brain. The motor disorders of cerebral palsy are often accompanied by disturbances of sensation, perception, cog...
Source: PediatricEducation.org - March 9, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Evidence Base of Clinical Studies on Qi Gong: A Bibliometric Analysis.
CONCLUSIONS: Qigong research publications have been increasing gradually. Reports on study types, participants, Qigong Intervention, and outcomes are diverse and inconsistent. There is an urgent need to develop a set of reporting standards for various interventions of Qigong. Further trials of high methodological quality with sufficient sample size and real world studies are needed to verify the effects of Qigong in health and disease management. PMID: 32444061 [PubMed - as supplied by publisher]
Source: Complementary Therapies in Medicine - April 30, 2020 Category: Complementary Medicine Authors: Zhang YP, Hu RX, Han M, Lai BY, Liang SB, Chen BJ, Robinson N, Chen K, Liu JP Tags: Complement Ther Med Source Type: research

Development of an indicator set for the evaluation of the population-based integrated healthcare model 'Gesundes Kinzigtal' (Healthy Kinzigtal).
CONCLUSION: On the basis of a broadly based research and participatory development process, a set of indicators has been developed that enables comprehensive evaluation of the regional quality of care of cross-indication, integrated care models focusing on common diseases. In order to be able to increasingly evaluate aspects of care coordination and patient orientation, health promotion as well as nursing, palliative and emergency care in the future, it would be helpful if routine data were collected or made accessible in these areas as well. PMID: 32467041 [PubMed - as supplied by publisher]
Source: Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen - May 30, 2020 Category: Health Management Tags: Z Evid Fortbild Qual Gesundhwes Source Type: research

Diagnosis to therapy: The future of image-guided patient management
(Society of Nuclear Medicine and Molecular Imaging) SNMMI's Virtual Annual Meeting will convene more than 6,000 attendees from around the globe to share novel research on new and better ways to diagnose and treat cancers, inflammation, arthritis, chronic pain, stroke, brain disease, and more.The focus is on precision medicine--improving patients' lives by developing new ways to diagnose earlier and more accurately, delivering the most effective therapy for a specific patient's disease, and monitoring and adjusting treatment to ensure optimum results.
Source: EurekAlert! - Cancer - July 7, 2020 Category: Cancer & Oncology Source Type: news

Effect of kinesio taping on hemiplegic shoulder pain: A systematic review and meta-analysis of randomized controlled trials.
CONCLUSION: This meta-analysis suggests a beneficial effect of kinesio taping for reducing shoulder subluxation, improving motor function of the upper limb and activities of daily living in patients with hemiplegic shoulder pain post-intervention, which could not be interpreted simply as a placebo effect. And it was associated with reduced pain for patients with chronic stroke. PMID: 33063559 [PubMed - as supplied by publisher]
Source: Clinical Rehabilitation - October 16, 2020 Category: Rehabilitation Authors: Deng P, Zhao Z, Zhang S, Xiao T, Li Y Tags: Clin Rehabil Source Type: research

The Influence of Age on Central Effects of Methylnaltrexone in Patients with Opioid-Induced Constipation
ConclusionsMethylnaltrexone use did not adversely affect pain control, opioid withdrawal effects, or AEs while providing effective RFL, regardless of age. These results suggest that age does not appear to influence the safety and efficacy of methylnaltrexone for OIC. Further research is needed to assess the impact of other factors that alter BBB permeability, such as dementia, stroke, or drug interactions, on the safety and efficacy of methylnaltrexone.Clinical Trial Registration NumbersStudy 302, NCT00402038; study 3200K1-4000, NCT00672477; study 3200K1-3356, NCT00529087; study 3201, NCT01186770.
Source: Drugs and Aging - March 31, 2021 Category: Geriatrics Source Type: research

Sickle Cell Disease and Pain: Is it all Vaso-occlusive Crises?
Discussion: CP and NP should be assessed during routine care of sickle cell pain so that targeted therapies can be applied.
Source: The Clinical Journal of Pain - July 15, 2021 Category: Anesthesiology Tags: Original Articles Source Type: research

Summary: International Kidney Cancer Symposium
Conclusions:  Ideal ischemia time is 20-25 minutes or less improves short and long term renal function. >25 minutes carried 5 year risk of new onset stage 4 CKD No differences on GFR for cold vs. warm ischemia times Preoperative GFR and the percent of kidney preserved was a better predictor of post op GFR.  No ischemia preserves renal function better than warm. Longer cold ischemia times were equivalent to shorter warm ischemia times. Quality and quantity of the remaining kidney is associated with ultimate renal function. Robotics in RCC Surgery Gennady Bratslavsky, MD The opening question ...
Source: Kidney Cancer Association - December 15, 2011 Category: Urology & Nephrology Source Type: news

Pulmonary Embolism and Cardiac Tamponade in Critical Care Patients with COVID-19; Telemedicine's Role in Developing Countries: Case Reports and Literature Review
CONCLUSIONS: During admission, both patients had sudden deterioration characterized by oxygen desaturation and hypotension necessitating inotropic support. As a result, for both patients, bedside echocardiography was performed by the attending intensivist. Echocardiographic findings showed cardiac tamponade and acute pulmonary embolism, respectively, which were confirmed by a cardiologist through telemedicine technology. Proper emergency management was initiated, and both patients recovered well. Limited bedside transthoracic echocardiography had a front-line impact on the treatment and outcome of the two patients with COV...
Source: Pain Physician - August 2, 2021 Category: Anesthesiology Authors: Islam Mohammed Sheata Scott Richard Smith Heba Kamel Giustino Varrassi Farnad Imani Abdolreza Dayani Dariusz Myrcik Ivan Urits Omar Viswanath Sameh Salem Taha Source Type: research

Surgical treatment of symptomatic pineal cysts without hydrocephalus —meta-analysis of the published literature
ConclusionsAlthough the results support the role of surgery in the management of nhSPCs, they have to be interpreted with a great deal of caution as the current evidence is limited, consisting only of case reports and retrospective surgical series. Inherent to such studies are inhomogeneity and incompleteness of data, selection bias and bias related to assessment of outcome carried out by the treating surgeon in the majority of cases. Prospective studies with patient-reported and objective outcome assessment are needed to provide higher level of evidence.
Source: Acta Neurochirurgica - December 2, 2021 Category: Neurosurgery Source Type: research

Surgical treatment of symptomatic pineal cysts without hydrocephalus-meta-analysis of the published literature
CONCLUSIONS: Although the results support the role of surgery in the management of nhSPCs, they have to be interpreted with a great deal of caution as the current evidence is limited, consisting only of case reports and retrospective surgical series. Inherent to such studies are inhomogeneity and incompleteness of data, selection bias and bias related to assessment of outcome carried out by the treating surgeon in the majority of cases. Prospective studies with patient-reported and objective outcome assessment are needed to provide higher level of evidence.PMID:34854993 | DOI:10.1007/s00701-021-05054-0
Source: Pain Physician - December 2, 2021 Category: Anesthesiology Authors: Riccardo Masina Ali Ansaripour Vladim ír Beneš Moncef Berhouma Joham Choque-Velasquez Per Kristian Eide Stepan Fedorko Steffen Fleck Juha Hernesniemi Andrzej Koziarski Martin M ájovský Andrzej Podgorski Henry Schroeder Charles Teo Andreas W Unterberg Source Type: research