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Condition: Hypertension
Procedure: Anesthesia

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Total 235 results found since Jan 2013.

Pharmacological modification of the perioperative stress response in non-cardiac surgery
The perioperative period is associated with alterations in the neuroendocrine, metabolic, and immune systems, referred to as 'stress response'. The resultant increased sympathetic activity and elevated serum concentrations of catecholamines may adversely affect the cardiovascular system resulting in cardiovascular instability (hypertension, tachycardia, arrhythmia), morbidity (myocardial ischemia, myocardial infarction, stroke) and mortality (cardiac death, fatal stroke), particularly in patients at elevated cardiovascular risk and with reduced cardiovascular reserve.
Source: Best Practice and Research. Clinical Anaesthesiology - April 5, 2016 Category: Anesthesiology Authors: Hans-Joachim Priebe Source Type: research

Pharmacological modification of the perioperative stress response in noncardiac surgery
The perioperative period is associated with alterations in the neuroendocrine, metabolic, and immune systems, referred to as “stress response.” The resultant increased sympathetic activity and elevated serum concentrations of catecholamines may adversely affect the cardiovascular system, resulting in cardiovascular instability (hypertension, tachycardia, and arrhythmia), morbidity (myocardial ischemia, myocardial infarction, and stroke), and mortality (cardiac death and fatal stroke), particularly in patients at an elevated cardiovascular risk and with reduced cardiovascular reserve.
Source: Best Practice and Research. Clinical Anaesthesiology - April 5, 2016 Category: Anesthesiology Authors: Hans-Joachim Priebe Tags: 4 Source Type: research

Right ventricular end-diastolic stiffness heralds right ventricular failure in monocrotaline-induced pulmonary hypertension.
Abstract Recent studies suggest right ventricular (RV) stiffness is important in pulmonary hypertension (PH) prognosis. Smaller stroke volume (SV) variation after a certain RV end-diastolic pressure (EDP) respiratory variation as assessed by spectral transfer function (STF) may identify RV stiffness. Our aim was to evaluate RV stiffness in monocrotaline (MCT)-induced PH progression and to validate STF gain between EDP and SV as marker of stiffness. Seven-week old male Wistar rats randomly injected with 60mg.Kg(-1) MCT or vehicle were divided into 3 groups (n=12 each) according to cardiac index (CI): controls (Ctrl...
Source: American Journal of Physiology. Heart and Circulatory Physiology - July 28, 2016 Category: Physiology Authors: Alaa M, Abdellatif M, Tavares-Silva M, Oliveira-Pinto J, Lopes L, Leite S, Leite-Moreira AF, Lourenço AP Tags: Am J Physiol Heart Circ Physiol Source Type: research

Epidural therapy for the treatment of severe pre-eclampsia in non labouring women.
CONCLUSIONS: Currently, there is insufficient evidence from randomised controlled trials to evaluate the effectiveness, safety or cost of using epidural therapy for treating severe pre-eclampsia in non-labouring women.High-quality randomised controlled trials are needed to evaluate the use of epidural agents as therapy for treatment of severe pre-eclampsia. The rationale for the use of epidural is well-founded. However there is insufficient evidence from randomised controlled trials to show that the effect of epidural translates into improved maternal and fetal outcomes. Thus, there is a need for larger, well-designed stud...
Source: Cochrane Database of Systematic Reviews - November 28, 2017 Category: General Medicine Authors: Ray A, Ray S Tags: Cochrane Database Syst Rev Source Type: research

Unmasking of estrogen dependent changes in left ventricular structure-function in aged female rats: A potential model for pre-HFpEF.
This article is protected by copyright. All rights reserved. PMID: 30681142 [PubMed - as supplied by publisher]
Source: The Journal of Physiology - January 25, 2019 Category: Physiology Authors: Bustamante M, Garate-Carrillo A, Ito B, Garcia R, Carson N, Ceballos G, Ramirez-Sanchez I, Omens J, Villarreal F Tags: J Physiol Source Type: research

Decompressive Craniectomy for Traumatic Brain Injury: Postoperative Cerebral Hemodynamic Evaluation
Conclusion: There is a wide heterogeneity of postoperative cerebral hemodynamic findings among TBI patients who underwent DC, including hemodynamic heterogeneity between their cerebral hemispheres. DC was proved to be effective for the treatment of cerebral oligoemia. Our data support the concept of heterogeneous nature of the pathophysiology of the TBI and suggest that DC as the sole treatment modality is insufficient. Introduction Decompressive craniectomy (DC) may effectively decrease intracranial pressure (ICP) and increase cerebral perfusion pressure (CPP) in traumatic brain injury (TBI) patients with refracto...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Decompressive Craniectomy for Traumatic Brain Injury: Postoperative TCD Cerebral Hemodynamic Evaluation
Conclusion: There is a wide heterogeneity of postoperative cerebral hemodynamic findings among TBI patients who underwent DC, including hemodynamic heterogeneity between their cerebral hemispheres. DC was proved to be effective for the treatment of cerebral oligoemia. Our data support the concept of heterogeneous nature of the pathophysiology of the TBI and suggest that DC as the sole treatment modality is insufficient. Introduction Decompressive craniectomy (DC) may effectively decrease intracranial pressure (ICP) and increase cerebral perfusion pressure (CPP) in traumatic brain injury (TBI) patients with refracto...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Is Aberrant Reno-Renal Reflex Control of Blood Pressure a Contributor to Chronic Intermittent Hypoxia-Induced Hypertension?
This study demonstrated unaltered vascular conductance in response to lumbar sympathetic stimulation in CIH-exposed rats. Aortic compliance was increased and estimated blood volume was unchanged in CIH-exposed rats. Increased blood pressure was related to an increase in cardiac output, which was confirmed by echocardiography (Lucking et al., 2014). It is suggested therefore that hypertension in the CIH model can be evoked by over-excitation of the cardiac arm of sympathetic nervous system (SNS), even before mechanisms of enhanced peripheral vasoconstriction and endothelial dysfunction are initiated (Naghshin et al., 2009)....
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

Patients Requiring Conversion to General Anesthesia during Endovascular Therapy Have Worse Outcomes: A Post Hoc Analysis of Data from the SAGA Collaboration INTERVENTIONAL
CONCLUSIONS: Patients undergoing conversion had significantly worse outcome compared with patients remaining in conscious sedation. No factor was identified that predicted conversion from conscious sedation to general anesthesia.
Source: American Journal of Neuroradiology - December 11, 2020 Category: Radiology Authors: Simonsen, C. Z., Schönenberger, S., Henden, P. L., Yoo, A. J., Uhlmann, L., Rentzos, A., Bösel, J., Valentin, J., Rasmussen, M. Tags: INTERVENTIONAL Source Type: research

Effects of Enhanced Intracranial Pressure on Blood Pressure and the Cardio-Ankle Vascular Index in Rabbits.
CONCLUSION: Increased ICP causes an increase in BP and CAVI, suggesting that enhanced stiffness of the muscular arteries contributes to high BP. Blocking the autonomic nervous system with hexamethonium suppresses the increase in BP and CAVI, indicating that these increases are mediated by activation of the autonomic nervous system. PMID: 33473056 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - January 23, 2021 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

The Effects of Amino Acids Enriched Del Nido Cardioplegia on Myocardial Leucocyte Accumulation and Ventricular Functions in Patients Undergoing Coronary Artery Bypass Grafting Surgery
CONCLUSION: Our study findings show that glutamate-aspartate supplemented del Nido cardioplegia significantly decrease myocardial PMNL accumulation with reduced release of biochemical markers, including cardiac troponin-I, TNF-alpha, and Pro-Bnp. Our study results demonstrated that amino acids supplementation in del Nido cardioplegia has some advantages in CABG patients, including the decrease of perioperative myocardial infarction and increase significantly the left ventricular functions including ventricular SVI and CI.PMID:33635267 | DOI:10.1532/hsf.3265
Source: The Heart Surgery Forum - February 26, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Zeki Temizturk Davut Azboy Ayhan Uysal Source Type: research