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Condition: Hypertension
Procedure: Anesthesia

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Total 235 results found since Jan 2013.

Sickle Cell Disease Subjects Have a Distinct Abnormal Autonomic Phenotype Characterized by Peripheral Vasoconstriction With Blunted Cardiac Response to Head-Up Tilt
Conclusion We have shown that SCD subjects are much more likely than non-SCD subjects to have impaired cardiac, but intact peripheral responses to orthostatic stress induced by HUT. These abnormal responses are associated with low baseline cardiac parasympathetic activity, independent of hemoglobin level. The classification of autonomic phenotypes based on HUT response may have potential use for predicting disease severity, guiding and targeting treatments/interventions to alleviate the risk of adverse outcomes in SCD. Ethics Statement All experiments were conducted at Children’s Hospital Los Angeles (CHLA). The ...
Source: Frontiers in Physiology - April 10, 2019 Category: Physiology Source Type: research

Combination of Dexmedetomidine and Ketamine for Magnetic Resonance Imaging Sedation
Conclusions: The efficacy of DEX–KET sedation was comparable to that of midazolam for MRI examination. DEX–KET was related to shorter scan time and lower occurrence of complications compared to midazolam. Introduction Neurocritically ill patients often require brain magnetic resonance imaging (MRI) in addition to conventional neurological evaluations. Brain MRI can reveal structural lesions with a high sensitivity due to its excellent spatial resolution and enhanced soft tissue contrast (1–3). To acquire MRI images, patients' cooperation is imperative. However, keeping patients with ...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Increased blood pressure variability during general anaesthesia is associated with worse outcomes after mechanical thrombectomy: a prospective observational cohort study
Conclusions Increased intraprocedural BPV was more likely to have poor functional outcome in patients with LVO following MT with general anaesthesia. This finding indicates that special precautions should be taken to minimise BP fluctuation during procedure.
Source: BMJ Open - October 5, 2022 Category: General Medicine Authors: Xu, C., Jin, T., Chen, Z., Zhang, Z., Zhang, K., Mao, H., Ye, S., Geng, Y., Shi, Z. Tags: Open access, Neurology Source Type: research

Outcomes of Carotid Stenting in Patients with Fibromuscular Dysplasia
CONCLUSION: Carotid artery stenting for fibromuscular dysplasia is a feasible and safe procedure with favorable technical success, low neurological complications, and good clinical outcomes at 1-year follow-up.PMID:36400362 | DOI:10.1016/j.jvs.2022.10.040
Source: Atherosclerosis - November 18, 2022 Category: Cardiology Authors: Jesus Porras-Colon Carla K Scott Alejandro Pizano Anna Driessen Carlos H Timaran John G Modrall Shirling Tsai Melissa L Kirkwood Bala Ramanan Source Type: research

Predictors of Cervical Bleeding after Carotid Endarterectomy
Conclusions: Postoperative severe bleeding after carotid surgery in our institution is not an uncommon complication. Its incidence is within the range reported in the literature, but it is not associated with major complications or mortality. Antiplatelet treatment with clopidogrel is the main risk factor associated with reintervention. Other factors, such as coagulation control, postoperative hypertension management, and the use of an autologous patch, could help reduce its incidence.
Source: Annals of Vascular Surgery - September 30, 2013 Category: Surgery Authors: Sara Mercedes Morales Gisbert, Vicente Andrés Sala Almonacil, Jose Miguel Zaragozá García, Beatriz Genovés Gascó, Francisco Julián Gómez Palonés, Eduardo Ortiz Monzón Tags: Clinical Research Source Type: research

Discharge on the First Postoperative Day after Elective Carotid Endarterectomy
Conclusion: In this study, the majority of patients undergoing elective CEA were discharged safely on the first postoperative day. Social reasons, rather than medical reasons, underlied most cases of later discharge. There were no unplanned readmissions for complications of CEA.
Source: Annals of Vascular Surgery - December 23, 2013 Category: Surgery Authors: Pierre Van den Brande, Isolde Van Heymbeeck, Erik Debing, Dimitri Aerden, Karl von Kemp, Leslie Moerman, Chris Verborgh, Patrick Haentjens Tags: Clinical Research Source Type: research

Arterial Waveform Analysis
This article will focus on the principles of arterial waveform analysis and their determinants, components of the arterial system, and arterial pulse contour. It will also address the advantage of measuring real-time cardiac output by the arterial waveform and the benefits to measuring stroke volume variation. Arterial waveform analysis has gained a large interest in the overall assessment and management of the critically ill and those at risk for hemodynamic deterioration.
Source: Best Practice and Research Clinical Anaesthesiology - November 1, 2014 Category: Anesthesiology Source Type: research

UCLA researchers provide first evidence of how obstructive sleep apnea damages the brain
Courtesy of Rajesh Kumar Brains with obstructive sleep apnea (left) and without UCLA researchers have reported the first evidence that obstructive sleep apnea contributes to a breakdown of the blood–brain barrier, which plays an important role in protecting brain tissue. The discovery, reported in the Sept. 1 issue of the Journal of Neuroimaging, could lead to new approaches for treating obstructive sleep apnea, which affects an estimated 22 million American adults. The disorder causes frequent interruptions in breathing during sleep because the airways narrow or become blocked. The blood–brain barrier limits harmful...
Source: UCLA Newsroom: Health Sciences - September 1, 2015 Category: Universities & Medical Training Source Type: news

Hemodynamics of Phenylephrine Infusion Versus Lower Extremity Compression During Spinal Anesthesia for Cesarean Delivery: A Randomized, Double-Blind, Placebo-Controlled Study.
CONCLUSIONS: An initial bolus of phenylephrine followed by a low-dose phenylephrine infusion was superior to leg wrapping and no intervention for the prevention of hypotension during spinal anesthesia for cesarean delivery. Phenylephrine prevented hypotension primarily by restoring systemic vascular resistance and did not cause hypertension or a clinically relevant reduction in cardiac output. Leg wrapping prevented hypotension compared with no intervention by limiting modest early spinal anesthesia-mediated venodilation. PMID: 26991619 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - March 19, 2016 Category: Anesthesiology Authors: Kuhn JC, Hauge TH, Rosseland LA, Dahl V, Langesæter E Tags: Anesth Analg Source Type: research

Right ventricular end-diastolic stiffness heralds right ventricular failure in monocrotaline-induced pulmonary hypertension
Recent studies suggest right ventricular (RV) stiffness is important in pulmonary hypertension (PH) prognosis. Smaller stroke volume (SV) variation after a certain RV end-diastolic pressure (EDP) respiratory variation as assessed by spectral transfer function (STF) may identify RV stiffness. Our aim was to evaluate RV stiffness in monocrotaline (MCT)-induced PH progression and to validate STF gain between EDP and SV as marker of stiffness. Seven-week-old male Wistar rats randomly injected with 60 mg/kg MCT or vehicle were divided into three groups (n = 12 each) according to cardiac index (CI): controls (Ctrl), preserved CI...
Source: AJP: Heart and Circulatory Physiology - September 30, 2016 Category: Cardiology Authors: Alaa, M., Abdellatif, M., Tavares-Silva, M., Oliveira-Pinto, J., Lopes, L., Leite, S., Leite-Moreira, A. F., Lourenco, A. P. Tags: Integrative Cardiovascular Physiology and Pathophysiology Source Type: research

Predicting Fluid Responsiveness in Acute Liver Failure: A Prospective Study.
CONCLUSIONS: PPV based on pulse contour analysis predicted fluid responsiveness in ALF. PMID: 27984249 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - December 13, 2016 Category: Anesthesiology Authors: Audimoolam VK, McPhail MJ, Willars C, Bernal W, Wendon JA, Cecconi M, Auzinger G Tags: Anesth Analg Source Type: research

Refractory Intracranial Hypertension: The Role of Decompressive Craniectomy.
Abstract Raised intracranial pressure (ICP) is associated with worse outcomes after acute brain injury, and clinical guidelines advocate early treatment of intracranial hypertension. ICP-lowering therapies are usually administered in a stepwise manner, starting with safer first-line interventions, while reserving higher-risk options for patients with intractable intracranial hypertension. Decompressive craniectomy is a surgical procedure in which part of the skull is removed and the underlying dura opened to reduce brain swelling-related raised ICP; it can be performed as a primary or secondary procedure. After tr...
Source: Anesthesia and Analgesia - August 10, 2017 Category: Anesthesiology Authors: Smith M Tags: Anesth Analg Source Type: research

Increased risk of dementia in people with previous exposure to general anesthesia: A nationwide population-based case-control study.
CONCLUSIONS: A history of previous exposure to surgery under GA might be associated with an increased risk of dementia, particularly in subjects who have undergone repeated exposure to GA. In addition, subjects who had received surgery under ETGA with comorbidities such as stroke, hypertension, diabetes mellitus, and atherosclerosis could have a potential relationship with dementia risk. PMID: 23896612 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - July 31, 2013 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

Measurement of maternal cerebral tissue hemoglobin on near‐infrared time‐resolved spectroscopy in the peripartum period
ConclusionsTRS‐20 can detect specific changes in maternal cerebral tissue hemoglobin level in response to physiological and pathophysiological changes in delivery. Thus, it represents a promising new conventional tool for maternal cerebral monitoring in the peripartum period.
Source: Journal of Obstetrics and Gynaecology Research - December 16, 2014 Category: OBGYN Authors: Kazunao Suzuki, Hiroaki Itoh, Mari Mukai, Kaori Yamazaki, Toshiyuki Uchida, Hideki Maeda, Motoki Oda, Etsuko Yamaki, Hiroaki Suzuki, Naohiro Kanayama Tags: Original Article Source Type: research

De Novo Headache During Pregnancy and Puerperium
Conclusion: De novo headache during pregnancy is relatively common and almost always leads to neurological referral.
Source: The Neurologist - December 28, 2015 Category: Neurology Tags: Review Article Source Type: research