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Condition: Hypertension
Procedure: PET Scan

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Total 427 results found since Jan 2013.

A nationwide population-based retrospective cohort study: increased risk of acute coronary syndrome in patients with ankylosing spondylitis.
Conclusions: AS patients are at higher risk of ACS compared with non-AS subjects. Management of CV risk factors should be taken into account for the treatment of patients with AS, especially for patients with co-morbidities of hypertension, DM, and cancer. PMID: 24134400 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Rheumatology - October 18, 2013 Category: Rheumatology Authors: Chou CH, Lin MC, Peng CL, Wu YC, Sung FC, Kao CH, Liu SH Tags: Scand J Rheumatol Source Type: research

Higher mortality rates among the elderly with mild traumatic brain injury: a nationwide cohort study
Conclusions: Mild traumatic brain injury is an independent significant risk factor for death in the elderly.
Source: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine - January 28, 2014 Category: Emergency Medicine Authors: Po-Liang ChengHsin-Yi LinYi-Kung LeeChen-Yang HsuChing-Chih LeeYung-Cheng Su Source Type: research

The Value of N-Terminal Pro-B-Type Natriuretic Peptide in Determining Antihypertensive Benefit: Observations From the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) Natriuretic Peptides
We investigated 3 hypotheses: (1) N-terminal pro–B-type natriuretic peptide (NT-proBNP) predicts cardiovascular disease events in patients with hypertension, (2) NT-proBNP is associated with blood pressure variability, and (3) NT-proBNP predicts benefit from antihypertensive regimens. The Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) randomized a subset of 6549 patients at risk with no history of coronary heart disease to either atenolol-based or amlodipine-based blood pressure–lowering treatment. During 5.5 years of follow-up, 485 cardiovascular disease cases accrued and were matched with 1367 controls. Ba...
Source: Hypertension - February 12, 2014 Category: Cardiology Authors: Welsh, P., Poulter, N. R., Chang, C. L., Sever, P. S., Sattar, N., on behalf of the ASCOT Investigators Tags: Cerebrovascular disease/stroke Natriuretic Peptides Source Type: research

Risk factors for prehypertension in the community: A prospective analysis from the Western New York Health Study
Conclusions: Results from this study suggest early dysregulation of glucose metabolism and weight gain over the lifespan may represent important risk factors for prehypertension in the general population.
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - December 20, 2013 Category: Nutrition Authors: R.P. Donahue, S. Stranges, L. Rafalson, J. Dmochowski, J. Dorn, M. Trevisan Tags: Electrolyte intake, blood pressure and vascular changes Source Type: research

Blood pressure variability: A new target to slow the progression of vascular damage in type 2 diabetes?
Hypertension is a widely recognized cardiovascular risk factor. Besides the correct measurement of systolic blood pressure (BP), of paramount importance in assessing cardiovascular risk, other BP features have been suggested to play a role; among these, the visit-to-visit BP variability is receiving growing support from the scientific literature. Observational studies link BP variability with carotid artery intima media thickness and atherosclerosis (), and in aging people it worsens cardiovascular prognosis and negatively affects cognitive function (). Post-hoc analyses of large trials, like the United Kingdom Transient I...
Source: Journal of Diabetes and Its Complications - December 6, 2013 Category: Endocrinology Authors: Anna Solini Tags: Editorials Source Type: research

Cardiovascular highlights from non-cardiology journals
Stenting of atherosclerotic renal artery disease fails to improve outcomes Atherosclerotic renal-artery stenosis is common among patients with cardiovascular disease and the condition may contribute to hypertension. The impact of renal artery angioplasty or stenting on the risk of clinical events among patients with atherosclerotic renal disease remains poorly defined. In the Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL) study, 947 patients atherosclerotic renal-artery stenosis and hypertension and/or chronic kidney disease were randomized to medical therapy alone or medical therapy plus renal artery ste...
Source: Heart - April 16, 2014 Category: Cardiology Authors: Bradley, S. M. Tags: Journal scan Source Type: research

Lipid lowering in patients with treatment-resistant hypertension: an analysis from the Treating to New Targets (TNT) trial
Conclusion In subjects with TRH, intensive lipid lowering with atorvastatin 80 mg is associated with a significant reduction in cardiovascular events.
Source: European Heart Journal - July 15, 2014 Category: Cardiology Authors: Bangalore, S., Fayyad, R., Laskey, R., DeMicco, D., Deedwania, P., Kostis, J. B., Messerli, F. H., Treating to New Targets Steering Committee and Investigators Tags: Heart failure/cardiomyopathy Source Type: research

Clinical, familial, and neuroimaging features of CADASIL‐like patients
ConclusionsOur experience highlights the growing number of patients presenting with a high suspicion of a cerebral small vessel disease with an autosomal dominant pattern of inheritance and a phenotype closely similar to that of CADASIL but without NOTCH3 mutations. This group remains to be characterized from the genetic point of view. The role of other genes or NOTCH3 alterations on exons other than 2‐23 or introns has to be further assessed.
Source: Acta Neurologica Scandinavica - August 11, 2014 Category: Neurology Authors: S. Nannucci, F. Pescini, B. Bertaccini, S. Bianchi, L. Ciolli, R. Valenti, M. T. Dotti, A. Federico, D. Inzitari, L. Pantoni Tags: Original Article Source Type: research

Impact of somatic comorbidities on quality of life of patients living with epilepsy in Sagamu, Nigeria
ConclusionSomatic comorbidity is prevalent in this population with significant impact on their quality of life. We emphasize the need to screen for and reduce the numbers of somatic comorbidities in PWE as this can improve their quality of life.
Source: Acta Neurologica Scandinavica - September 11, 2014 Category: Neurology Authors: Philip B. Adebayo, Rufus O. Akinyemi, Folashade Oluwole, Shamsideen A. Ogun, Adesola Ogunniyi Tags: Original Article Source Type: research

Arterial stiffness as a risk factor for cerebral aneurysm
ConclusionsThe baPWV was associated with intracranial saccular aneurysms even after adjustment of hypertension and smoking. Assessment of the baPWV may aid the evaluation of the intracranial saccular aneurysm and the development of strategies for screening patients with intracranial saccular aneurysms.
Source: Acta Neurologica Scandinavica - September 1, 2014 Category: Neurology Authors: H. Matsukawa, M. Shinoda, M. Fujii, A. Uemura, O. Takahashi, Y. Niimi Tags: Original Article Source Type: research

Cerebral microbleeds in a multiethnic elderly community: Demographic and clinical correlates
Conclusions: Microbleeds in deep and lobar locations are associated with worse outcomes than microbleeds in either location alone, although the presence of lobar microbleeds appears to be more clinically relevant.Highlights:
Source: Journal of the Neurological Sciences - July 21, 2014 Category: Neurology Authors: Anne F. Wiegman, Irene B. Meier, Nicole Schupf, Jennifer J. Manly, Vanessa A. Guzman, Atul Narkhede, Yaakov Stern, Sergi Martinez-Ramirez, Anand Viswanathan, José A. Luchsinger, Steven M. Greenberg, Richard Mayeux, Adam M. Brickman Tags: Original Articles Source Type: research

Unfavorable outcome of aggressive lowering of high blood pressure. Case report.
Abstract Cerebral autoregulation is essential in the maintenance of cerebral blood flow. Due to this autoregulation, cerebral perfusion is constant in healthy subjects if blood pressure values are between 50-150 mmHg. In hypertensive patients the curve is right-shifted towards higher blood pressure values (pathological autoregulation). Aggressive blood pressure reduction can lead to severe ischaemia. The authors report the history of a 73-year-old man with the background history of widespread atherosclerotic disease. The patient complained about headache and dizziness and was found to have high blood pressure (160...
Source: Orvosi Hetilap - October 1, 2014 Category: Journals (General) Authors: Kuperczkó D, Csécsei P, Komáromy H, Szapáry L, Fehér G Tags: Orv Hetil Source Type: research

Pneumonia: When Antibiotics Are Not the Answer
We present the case of an 88-year-old bedridden man, with hypertension, multiple myeloma, coronary artery disease, ischemic stroke, seizures, dysphagia, and constipation under treatment with mineral oil. He was brought to the emergency department after 3 days of cough, dysphagia, and dyspnea, following a recent hospitalization, due to a health care–associated pneumonia. A chest computed tomography scan obtained showed bilateral multifocal opacities with consolidates described as Hounsfield units of −62, consistent with fat. A diagnosis of lipoid pneumonia was done, and mineral oil was discontinued. Given the patient’...
Source: Infectious Diseases in Clinical Practice - October 31, 2014 Category: Infectious Diseases Tags: Case Reports Source Type: research

Topography and associations of perivascular spaces in healthy adults: The Kashima Scan Study
Conclusions: In a neurologically healthy cohort, the associations of PVS differ according to their topography. PVS distribution may be useful for the early detection and classification of small vessel disease.
Source: Neurology - December 1, 2014 Category: Neurology Authors: Yakushiji, Y., Charidimou, A., Hara, M., Noguchi, T., Nishihara, M., Eriguchi, M., Nanri, Y., Nishiyama, M., Werring, D. J., Hara, H. Tags: MRI, Other cerebrovascular disease/ Stroke, Alzheimer's disease, Cohort studies, Risk factors in epidemiology ARTICLE Source Type: research

Variables Associated with Effects on Morbidity in Older Adults Following Disasters
Conclusion Older adults are at a known risk for increased morbidity during and shortly after disasters and catastrophic events, especially in the presence of multiple co-morbidities such as hypertension, diabetes, stroke, and heart disease. Other factors, such as the need for prescription medications, low social support, visual and hearing impairment, impaired mobility, and poor economic status, have also been associated with an increased risk of negative health outcomes. The utilization of existing databases of older adults’ vulnerabilities and the measurement of the prevalence of these risk factors in the community may...
Source: PLOS Currents Disasters - December 5, 2014 Category: Global & Universal Authors: jenkins at jhmi.edu Source Type: research