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Stroke in Commercial Flights Brief Reports
Conclusions— We found a low incidence of stroke in the setting of air travel. Economy class stroke syndrome and arterial dissection were well represented in our sample. However, the main pathogenesis was atherothrombosis with a high proportion of patients with high carotid stenosis.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Alvarez-Velasco, R., Masjuan, J., DeFelipe, A., Corral, I., Estevez-Fraga, C., Crespo, L., Alonso-Canovas, A. Tags: Epidemiology, Risk Factors, Ischemic Stroke, Transient Ischemic Attack (TIA) Brief Reports Source Type: research

Influence of Sex on Stroke Prognosis: A Demographic, Clinical, and Molecular Analysis
Conclusion Our data suggest that women who suffer from IS present with a poorer functional outcome than men at 3-months, regardless of other preclinical and clinical factors during the acute phase. These relationships seem to be mediated by atrial dysfunction and inflammation. The inflammatory response is slightly higher in women; however, there are no sex differences in their functional behavior. There is a probable relationship between the molecular marker of atrial dysfunction NT-proBNP and worse functional outcome in women, and the connection seems to be more important in cardioembolic stroke patients. In patients wi...
Source: Frontiers in Neurology - April 16, 2019 Category: Neurology Source Type: research

Differences in the distribution of risk factors for stroke among the high‐risk population in urban and rural areas of Eastern China
ConclusionAmong the population at high risk of stroke, there were significant differences in the distribution of the following risk factors between the urban and rural groups: hypertension, atrial fibrillation, dyslipidemia, lack of physical exercise, and a previous stroke. As the Chinese lifestyle has changed rapidly with the growth of economy and society during the past 3 decades, the incidence of risk factors for stroke in China has become similar to that in the Western countries. Hypertension, diabetes, hypercholesterolemia, smoking, atrial fibrillation, physical inactivity, obesity, and stroke family history are the ...
Source: Brain and Behavior - February 29, 2016 Category: Neurology Authors: Te Mi, Shangwen Sun, Yifeng Du, Shougang Guo, Lin Cong, Mingfeng Cao, Qinjian Sun, Yi Sun, Chuanqiang Qu Tags: Original Research Source Type: research

The One-Year Attributable Cost of Post-stroke Dysphagia
This study sought to address this issue by examining the 1-year cost associated with a diagnosis of dysphagia post-stroke in South Carolina. Furthermore, this study investigated whether ethnicity and residence differences exist in the cost of dysphagia post-stroke. Data on 3,200 patients in the South Carolina Medicare database from 2004 who had ICD-9 codes for ischemic stroke, 434 and 436, were retrospectively included in this study. Differences between persons with and without dysphagia post-stroke were compared with respect to age, gender, ethnicity, mortality, length of stay, comorbidity, rurality, discharge disposition...
Source: Dysphagia - September 27, 2014 Category: Speech Therapy Source Type: research

Rheumatic Valve Disease and Stroke. A Public Health Problem in Countries in Way of Develop (P1.288)
Conclusions: In our population RVD with or without AF is the main cause of cerebral ischemia, just preceded by thrombosis of large arteries, affecting young and productive people, which severely impacts the economy of families and country that walking towards development. Mexico along with other emerging countries needs to implement public health programs in the early diagnosis and treatment of this health problem.Disclosure: Dr. Mendez-Dominguez has nothing to disclose. Dr. Arias-Fernandez has nothing to disclose. Dr. Aguirre-Delfin has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Mendez-Dominguez, A., Arias-Fernandez, J., Aguirre-Delfin, M. Tags: Global Health: Infectious Disease, Capacity Building, and Other Source Type: research

Associations between Ischemic Stroke Follow-Up, Socioeconomic Status, and Adherence to Secondary Preventive Drugs in Southern Sweden: Observations from the Swedish Stroke Register (Riksstroke)
Conclusions: The use of secondary preventive drugs decreases over the first year after stroke and remains suboptimal. Specific reasons for nonadherence warrant further study.Neuroepidemiology 2017;48:32-38
Source: Neuroepidemiology - February 24, 2017 Category: Epidemiology Source Type: research

Trimethylamine-N-oxide: a potential biomarker and therapeutic target in ischemic stroke
This article reviews the production of TMAO, TMAO’s relationship with different etiological types of ischemic stroke, and the possibility of reducing TMAO levels to improve the prognosis of ischemic stroke.
Source: Frontiers in Neurology - April 21, 2023 Category: Neurology Source Type: research

The effect of occupational exposure to noise on ischaemic heart disease, stroke and hypertension: A systematic review and meta-analysis from the WHO/ILO Joint Estimates of the Work-Related Burden of Disease and Injury
CONCLUSIONS: For acquiring IHD, we judged the existing body of evidence from human data to provide "limited evidence of harmfulness"; a positive relationship is observed between exposure and outcome where chance, bias, and confounding cannot be ruled out with reasonable confidence. For all other included outcomes, the bodies of evidence were judged as "inadequate evidence of harmfulness". Producing estimates for the burden of CVD attributable to occupational exposure to noise appears to not be evidence-based at this time.PROTOCOL IDENTIFIER: 10.1016/j.envint.2018.09.040.PROSPERO REGISTRATION NUMBER: CRD42018092272.PMID:336...
Source: Environment International - February 22, 2021 Category: Environmental Health Authors: Liliane R Teixeira Frank Pega Angel M Dzhambov Alicja Bortkiewicz Denise T Correa da Silva Carlos A F de Andrade Elzbieta Gadzicka Kishor Hadkhale Sergio Iavicoli Martha S Mart ínez-Silveira Ma łgorzata Pawlaczyk-Łuszczyńska Bruna M Rondinone Jadwiga Source Type: research

Correspondence The future of stroke therapy must not be mired by past arguments
Stroke is the leading cause of disability and the fifth leading cause of death in the UK, costing the UK economy more than £7 billion per year.1 At present, the only therapeutic approved by the UK National Institute for Health and Care Excellence (NICE) for the treatment of ischaemic stroke is thrombolysis using recombinant tissue-type plasminogen activator (rtPA). However, rtPA is only effective in patients who present within 4·5 h of stroke onset, with a number needed to treat for benefit of 3·6 before 90 min, rising to 5·9 between 3 h and 4·5 h.
Source: LANCET - August 14, 2015 Category: Journals (General) Authors: Alastair M Buchan, Hasneen G Karbalai, Brad A Sutherland Tags: Correspondence Source Type: research

Prevention and follow-up in thromboembolic ischemic stroke: Do we need to think out of the box?
Stroke is one of the most debilitating thrombotic diseases, and world-wide it is estimated that by, 2030 23 million people will be affected. Except for the impact on the individual families, the world economy is also affected adversely. Although the medical treatment and knowledge of stroke are both increasing and well-researched, we still do not see a light in the tunnel. Currently various diagnostic tests are employed to determine the specific type of ischemic stroke as classified by the TOAST criteria.
Source: Thrombosis Research - November 4, 2015 Category: Hematology Authors: Albe C. Swanepoel, Etheresia Pretorius Tags: Review Article Source Type: research

Neuronal Death Mechanisms and Therapeutic Strategy in Ischemic Stroke
AbstractIschemic stroke caused by intracranial vascular occlusion has become increasingly prevalent with considerable mortality and disability, which gravely burdens the global economy. Current relatively effective clinical treatments are limited to intravenous alteplase and thrombectomy. Even so, patients still benefit little due to the short therapeutic window and the risk of ischemia/reperfusion injury. It is therefore urgent to figure out the neuronal death mechanisms following ischemic stroke in order to develop new neuroprotective strategies. Regarding the pathogenesis, multiple pathological events trigger the activa...
Source: Neuroscience Bulletin - May 5, 2022 Category: Neuroscience Source Type: research

The therapeutic benefits of intravenously administrated nanoparticles in stroke and age-related neurodegenerative diseases
Curr Pharm Des. 2022 Jun 8. doi: 10.2174/1381612828666220608093639. Online ahead of print.ABSTRACTThe mean global lifetime risk of neurological disorders such as stroke, Alzheimer's disease (AD), and Parkinson's disease (PD) has shown a large effect on economy and society.Researchersare stillstruggling to find effective drugs to treatneurological disordersand drug delivery through the blood-brain barrier (BBB) is a major challenge to be overcome. The BBB is a specialized multicellular barrier between the peripheral blood circulation and the neural tissue. Unique and selective features of the BBB allow it to tightly control...
Source: Current Pharmaceutical Design - June 9, 2022 Category: Drugs & Pharmacology Authors: Mehdi Farhoudi Saeed Sadigh-Eteghad Javad Mahmoudi Afsaneh Farjami Afsaneh Farjami Mohammad Mahmoudian Sara Salatin Source Type: research

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