• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Early apixaban therapy after ischemic stroke in patients with atrial fibrillation
ConclusionsSymptomatic HT rates are likely to be low in randomized trials of DOAC initiation post-stroke. Recurrent ischemic stroke may be the major clinical outcome. These data may be used as expected event rates when calculating sample size requirements for future safety/efficacy trials of early versus late DOAC initiation after AF-related stroke.
Source: Journal of Neurology - January 3, 2021 Category: Neurology Source Type: research

Hyper-acute EEG alterations predict functional and morphological outcomes in thrombolysis-treated ischemic stroke: a wireless EEG study
AbstractOwing to the large inter-subject variability, early post-stroke prognosis is challenging, and objective biomarkers that can provide further prognostic information are still needed. The relation between quantitative EEG parameters in pre-thrombolysis hyper-acute phase and outcomes has still to be investigated. Hence, possible correlations between early EEG biomarkers, measured on bedside wireless EEG, and short-term/long-term functional and morphological outcomes were investigated in thrombolysis-treated strokes. EEG with a wireless device was performed in 20 patients with hyper-acute (<  4.5 h from onset) ant...
Source: Medical and Biological Engineering and Computing - December 4, 2020 Category: Biomedical Engineering Source Type: research

Early rehabilitation after stroke: relationship between the heart rate variability and functional outcome
ConclusionsThe presence of autonomic cardiovascular dysregulation in patients with subacute stroke was associated with adverse functional outcome after the early post ‐stroke rehabilitation.
Source: ESC Heart Failure - July 29, 2020 Category: Cardiology Authors: Nadja Scherbakov, Anush Barkhudaryan, Nicole Ebner, Stephan Haehling, Stefan D. Anker, Michael Joebges, Wolfram Doehner Tags: Original Research Article Source Type: research

Relationship between ischemic stroke locations, etiology subtypes, neurological outcomes, and autonomic cardiac function.
CONCLUSIONS: HRV measured after admission is related to the AIS infarction basin, TOAST subtypes, and neurological outcomes at discharge suggesting a possible role for HRV in evaluating AIS and identifying high-risk patients. PMID: 32701421 [PubMed - as supplied by publisher]
Source: Neurological Research - July 25, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Use of intracranial stent as rescue therapy after mechanical thrombectomy failure —9-year experience in a comprehensive stroke centre
ConclusionPlacement of an intracranial stent as rescue therapy after MT failure was associated with better clinical outcome without significant increase in haemorrhagic complications. We believe that this procedure should be appraised in these patients.
Source: Neuroradiology - June 29, 2020 Category: Radiology Source Type: research

Mechanical Thrombectomy in Acute Ischemic Stroke Using a  Manually Expandable Stent Retriever (Tigertriever) : Preliminary Single Center Experience.
CONCLUSION: The Tigertriever offers a safe and effective treatment option in ischemic stroke due to LVOs with reperfusion rates and a safety profile similar to alternative devices. The Tigertriever is a promising bail-out tool in complex cases. Its role as a first line device has to be evaluated in further prospective studies. PMID: 32529306 [PubMed - as supplied by publisher]
Source: Nuklearmedizin - June 10, 2020 Category: Radiology Authors: Will L, Maus V, Maurer C, Weber A, Weber W, Fischer S Tags: Clin Neuroradiol Source Type: research

Mechanical Thrombectomy in Acute Ischemic Stroke Using a  Manually Expandable Stent Retriever (Tigertriever)
ConclusionThe Tigertriever offers a  safe and effective treatment option in ischemic stroke due to LVOs with reperfusion rates and a safety profile similar to alternative devices. The Tigertriever is a promising bail-out tool in complex cases. Its role as a first line device has to be evaluated in further prospective studies.
Source: Clinical Neuroradiology - June 10, 2020 Category: Neurology Source Type: research

Untargeted metabolomics predicts the functional outcome of ischemic stroke.
CONCLUSION: Metabolomics is a potential method to explore the blood biomarkers of acute ischemic stroke. The patients with unfavorable outcomes had a lower PAF level compared to those with favorable outcomes. PMID: 32414667 [PubMed - as supplied by publisher]
Source: J Formos Med Assoc - May 12, 2020 Category: General Medicine Authors: Chi NF, Chang TH, Lee CY, Wu YW, Shen TA, Chan L, Chen YR, Chiou HY, Hsu CY, Hu CJ Tags: J Formos Med Assoc Source Type: research

Mechanical thrombectomy in acute middle cerebral artery M2 segment occlusion with regard to vessel involvement
ConclusionEVT in patients with acute M2-occlusion is safe and leads to a significant clinical improvement at discharge. No significant differences in clinical outcome or complications were found with regard to the localization of the M2-occlusion.
Source: Neurological Sciences - April 29, 2020 Category: Neurology Source Type: research

Machine learning volumetry of ischemic brain lesions on CT after thrombectomy —prospective diagnostic accuracy study in ischemic stroke patients
ConclusionNCCT ILV measured automatically by the Brainomix software might be considered a valuable radiological outcome measure.
Source: Neuroradiology - April 21, 2020 Category: Radiology Source Type: research

Temporal sustainability of guideline based door-to-needle times for intravenous thrombolysis for acute ischemic stroke
ConclusionIt is possible to sustainably reduce DTN time for IVT in AIS to well below the current 60 min benchmark with hospital system training and teamwork.
Source: Journal of Clinical Neuroscience - February 22, 2020 Category: Neuroscience Source Type: research

Clinical features and efficacy of reperfusion therapy in minor ischemic stroke patients with atrial fibrillation
AbstractThe efficacy of reperfusion therapy (RT) using intravenous infusion of recombinant tissue plasminogen activator and/or endovascular therapy for minor ischemic stroke (MIS) has not yet been established. The present study aimed to elucidate the clinical features of MIS patients with atrial fibrillation (AF) and examine whether they could be potential candidates for RT. Data of MIS patients, defined as those with a score  ≤ 5 on the National Institute of Health Stroke Scale, were extracted from patients admitted to our hospital between 2006 and 2018, and clinical characteristics were compared between the AF and ...
Source: Journal of Thrombosis and Thrombolysis - February 10, 2020 Category: Hematology Source Type: research

Thrombolysis safety and effectiveness in acute ischemic stroke patients with pre-morbid disability
ConclusionPatients with mRS 2 and 3 may benefit from rt-PA with a moderate risk of sICH and mortality.
Source: Journal of Clinical Neuroscience - December 25, 2019 Category: Neuroscience Source Type: research

Recanalization is the Key for Better Outcome of Thrombectomy in Basilar Artery Occlusion
ConclusionReperfusion is the major predictor of functional outcome in BAO in clinical practice. Failed recanalization resulted in a  13-fold increase of the risk of poor outcome. Successful recanalization is crucial to achieve a better functional outcome in BAO.
Source: Clinical Neuroradiology - December 22, 2019 Category: Neurology Source Type: research

Collateral Scores in Acute Ischemic Stroke
ConclusionAlthough collaterals are known to correlate with clinical outcome, none of the analyzed collateral scores sufficiently predicted outcome as a  standalone parameter.
Source: Clinical Neuroradiology - November 27, 2019 Category: Neurology Source Type: research

Pages: 1  2  3  4  5  6  7  8  9  10  11