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Condition: Anaphylactic Shock

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Total 7645 results found since Jan 2013.

Spontaneous food allergy in Was ‐/‐ mice occurs independent of FcεRI‐mediated mast cell activation
ConclusionsWas‐/‐ mice provide a model of food allergy with the advantage of mimicking polysensitization and low food‐antigen IgE titers as observed in humans with clinical food allergy. This model will facilitate studies on aberrant immune responses during spontaneous disease development. Our results imply that therapeutic targeting of the IgE/FcεRI activation cascade will not affect sensitization to food.This article is protected by copyright. All rights reserved.
Source: Allergy - June 10, 2017 Category: Allergy & Immunology Authors: Willem S. Lexmond, Jeremy A. Goettel, Benjamin F. Sallis, Katelyn McCann, Edmond H. H. M. Rings, Erika Jensen ‐Jarolim, Samuel Nurko, Scott B. Snapper, Edda Fiebiger Tags: Original Article: Experimental Allergy and Immunology Source Type: research

Meat allergy associated with α‐Gal – Closing diagnostic gaps by anti‐α‐Gal IgE immune profiling
ConclusionsDetection of individual sensitization patterns with different α‐Gal‐containing analytes provides the basis for an individual allergy diagnosis for α‐Gal sensitized patients. Higher amounts of α‐Gal in pork and beef innards compared to muscle meat as indicated by a higher staining intensity are a plausible explanation for the difference in allergic symptom severity.This article is protected by copyright. All rights reserved.
Source: Allergy - July 3, 2017 Category: Allergy & Immunology Authors: U. Jappe, S. Minge, B. Kreft, A. Ludwig, B. Przybilla, A. Walker, R. Varga, P. Seidel, T. Biedermann, W. Anem üller, A. Kromminga, F. Ruëff, H. Merk, N. Wagner, R. Treudler, M. Worm, I. Waldmann, J. Saloga, W. M. Becker, T. Goldmann, T. A. Platts‐Mill Tags: Original Article: Experimental Allergy and Immunology Source Type: research

The Efficacy of Oral Immunotherapy in Patients with Cow's Milk Allergy.
Abstract Cow's milk allergy is the most common type of food allergy that decrease the quality of life of patients and their families. The aim of this study was to evaluate the efficacy of oral immunotherapy in patients with cow's milk allergy. 14 patients above 3 years of age with a history of cow's milk allergy confirmed by positive double blind placebo controlled food challenge (DBPCFC) test, presence of serum IgE against cow's milk and positive SPT (skin prick test) were enrolled in this study. During the immunotherapy all patients received increasing amounts of cow's milk during three phases. The type and seve...
Source: Iranian Journal of Allergy, Asthma and Immunology - June 1, 2017 Category: Allergy & Immunology Authors: Ebrahimi M, Gharagozlou M, Mohebbi A, Hafezi N, Azizi G, Movahedi M Tags: Iran J Allergy Asthma Immunol Source Type: research

School nurse perspectives on school policies for food allergy and anaphylaxis.
CONCLUSION: With one-third of school nurses reporting an allergic reaction in the past year, schools use many strategies to minimize allergen exposures and increase anaphylaxis preparedness. Most school nurses favor these policies and acknowledge barriers to implementation. PMID: 29508717 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - March 1, 2018 Category: Allergy & Immunology Authors: Kao LM, Wang J, Kagan O, Russell A, Mustafa SS, Houdek D, Smith B, Gupta R Tags: Ann Allergy Asthma Immunol Source Type: research

Leaving the nest: improving food allergy management on college campuses.
CONCLUSION: The use of qualitative research methods, patient-centered design processes, and collaborations with diverse stakeholders-including pediatricians that care for adolescents-can provide a framework for designing coordinated systems and policies to provide comprehensive support to college students with food allergy. Next steps include rigorously testing implementation of the Spotlight intervention prototypes. PMID: 29679763 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - April 18, 2018 Category: Allergy & Immunology Authors: Dyer AA, O'Keefe A, Kanaley MK, Kao L, Gupta RS Tags: Ann Allergy Asthma Immunol Source Type: research

The Basophil Activation Test reduces the need for a food challenge test in children suspected of IgE ‐mediated cow's milk allergy
Conclusions and Clinical RelevanceThe BAT seems reliable and cost ‐effective to diagnose patients with an IgE‐mediated cow's milk allergy. In IgE sensitized patients a BAT might replace a DBPCFC. For non‐IgE sensitized patients presenting with mild symptoms we propose to consider a (double‐blind) extended (time) challenge test at home.This article is protected by copyright. All rights reserved.
Source: Clinical and Experimental Allergy - November 8, 2018 Category: Allergy & Immunology Authors: Janneke Ruinemans ‐Koerts, Yvonne Schmidt‐Hieltjes, A d Jansen, Huub F.J. Savelkoul, Annejet Plaisier, Petra van Setten Tags: Original Article ‐Clinical Allergy Source Type: research

An update on shellfish allergy
Purpose of review Shellfish is an important cause of food allergy worldwide, and a major cause of food-triggered anaphylaxis. Despite the wide variety of shellfish, there is considerable serological and clinical cross-reactivity of major shellfish allergens, and accurate diagnosis remains a challenge in the management of shellfish allergy. Recent findings Novel minor allergens have been discovered and characterized, and advances in component resolved diagnostics have provided insights into the prevalence of sensitization and their clinical importance in shellfish allergy. The extensive cross-reactivity between tropomy...
Source: Current Opinion in Allergy and Clinical Immunology - April 30, 2019 Category: Allergy & Immunology Tags: FOOD ALLERGY: Edited by Alessandro Fiocchi and Motohiro Ebisawa Source Type: research

Clinical Features and Culprit Food Allergens of Korean Adult Food Allergy Patients: A Cross-Sectional Single-Institute Study.
CONCLUSIONS: Wheat, fruits with or without PFAS, and crustaceans are important and frequent causative allergens in Korean adult FA; these allergens differ from those found in childhood FA. It is notable that non-classic allergies, such as PFAS, FDEIA, and α-Gal allergy, are the important causes of anaphylaxis in Korean adult FA. PMID: 31332982 [PubMed]
Source: Allergy, Asthma and Immunology Research - July 25, 2019 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Achieving The Quadruple Aim To Deliver Value-Based Allergy Care In An Ever-Evolving Healthcare System.
CONCLUSION: As healthcare systems continue to evolve, allergists and immunologists will play a key role in optimizing value by translating emerging evidence into practice and communicating novel approaches to prevent and treat allergic diseases. PMID: 32289524 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - April 10, 2020 Category: Allergy & Immunology Authors: Iglesia EGA, Greenhawt M, Shaker MS Tags: Ann Allergy Asthma Immunol Source Type: research

Coconut Allergy: Characteristics of Reactions and Diagnostic Predictors in a Pediatric Tertiary Care Center.
CONCLUSION: Although the rate of reactivity to coconut in sensitized individuals is low, half of reactions from consumption met criteria for anaphylaxis. Clinicians should be aware of the spectrum of reactions and diagnostic utility of sIgE and SPT. PMID: 33548470 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - February 3, 2021 Category: Allergy & Immunology Authors: Kruse L, Lor J, Yousif R, Pongracic JA, Fishbein AB Tags: Ann Allergy Asthma Immunol Source Type: research

Anaphylaxis across Europe: are pollen food syndrome and lipid transfer protein allergy so far apart?
Purpose of review Traditionally pollen-food syndrome (PFS) is considered to be a mild cross-reacting food allergy affecting only Northern Europe, with lipid transfer protein (LTP) allergy being more severe and mainly occurring in Southern Europe. This review seeks to update the reader on both types of plant food allergy and to determine whether the stereotypical presentations of these plant food allergies remain the same, with a particular focus on reaction severity. Recent findings Recent findings suggest that both these types of plant food allergy occur in children and adults. Although it is true that PFS alle...
Source: Current Opinion in Allergy and Clinical Immunology - September 15, 2022 Category: Allergy & Immunology Tags: ANAPHYLAXIS AND INSECT ALLERGY: Edited by Gianenrico Senna and Mariana Castells Source Type: research

Anaphylaxis in a tertiary adult allergy clinic: a retrospective review of 516 patients.
CONCLUSION: In this study, the second pattern of National Institute of Allergy and Infectious Disease (NIAID) and the Food Allergy and Anaphylaxis Network (FAAN) diagnostic criteria for anaphylaxis predominated among adult patients. Drugs were the leading triggering factor, followed by Hymenoptera stings, foods, latex, and exercise, respectively. Atopy, asthma, and allergic rhinitis were rarely detected. PMID: 23352528 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - January 30, 2013 Category: Allergy & Immunology Authors: Gelincik A, Demirtürk M, Yılmaz E, Ertek B, Erdogdu D, Colakoğlu B, Büyüköztürk S Tags: Ann Allergy Asthma Immunol Source Type: research

Allergists' self-reported adherence to anaphylaxis practice parameters and perceived barriers to care: an American College of Allergy, Asthma, and Immunology member survey.
CONCLUSION: Allergists overwhelmingly adhere to practice parameter recommendations for the treatment and management of anaphylaxis, including appropriate use of epinephrine as first-line treatment, educating patients, and testing to diagnose anaphylaxis and identify its triggers. Opportunities for improvement include preparing staff and patients for anaphylactic events, providing written action plans, and improving knowledge of referring physicians. PMID: 24267364 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - November 29, 2013 Category: Allergy & Immunology Authors: Fineman S, Dowling P, O'Rourke D Tags: Ann Allergy Asthma Immunol Source Type: research

Diet and food allergy development during infancy: Birth cohort study findings using prospective food diary data
Conclusions: An infant diet consisting of high levels of fruits, vegetables, and home-prepared foods is associated with less food allergy by the age of 2 years.
Source: Journal of Allergy and Clinical Immunology - July 25, 2013 Category: Allergy & Immunology Authors: Kate E.C. Grimshaw, Joe Maskell, Erin M. Oliver, Ruth C.G. Morris, Keith D. Foote, E.N. Clare Mills, Barrie M. Margetts, Graham Roberts Tags: Food, drug, insect sting allergy, and anaphylaxis Source Type: research

Component resolution reveals additional major allergens in patients with honeybee venom allergy
Conclusion: Analysis of a panel of CCD-free HBV allergens improved diagnostic sensitivity compared with use of rApi m 1 alone, identified additional major allergens, and revealed sensitizations to allergens that have been reported to be absent or underrepresented in therapeutic HBV preparations.
Source: Journal of Allergy and Clinical Immunology - January 21, 2014 Category: Allergy & Immunology Authors: Julian Köhler, Simon Blank, Sabine Müller, Frank Bantleon, Marcel Frick, Johannes Huss-Marp, Jonas Lidholm, Edzard Spillner, Thilo Jakob Tags: Food, drug, insect sting allergy, and anaphylaxis Source Type: research