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Total 325 results found since Jan 2013.

Japanese Legacy Cohort Studies: The Hisayama Study.
Authors: Ninomiya T Abstract The Hisayama Study is a population-based prospective cohort study designed to evaluate the risk factors for lifestyle-related diseases, such as stroke, coronary heart disease, hypertension, diabetes, and dementia, in a general Japanese population. The prospective follow-up surveys have been conducted in subjects aged 40 or older since 1961. Notable characteristics of this study include its high participation rate (70-80% of all residents aged 40 or older), high follow-up rate (99% or over), and high autopsy rate (approximately 75% of deceased cases). The Hisayama Study has provided valu...
Source: Journal of Epidemiology - October 10, 2018 Category: Epidemiology Tags: J Epidemiol Source Type: research

Differences in Clinical Features in Patients with Acute Coronary Syndrome and Stroke: Japanese Multicenter Registry Results.
Conclusions Patients' background characteristics were significantly different between those with ACS and stroke. Gender differences were also observed. PMID: 29877288 [PubMed - as supplied by publisher]
Source: Internal Medicine - June 9, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

Cultural Barriers in the Treatment of Dyslipidemia: A Survey of Japanese Physician Attitudes.
CONCLUSIONS: Awareness of target values for lipid management and of adverse reactions to drug therapy appears to vary somewhat depending on the participant's medical specialty. We also found that FH is probably underdiagnosed in Japan today. Further educations on proper diagnosis and management of dyslipidemia are required for physicians who are not specialized in cardiovascular health. PMID: 29780067 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - May 22, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Intensive Statins in Diabetes Misses Primary Endpoint: EMPATHY Intensive Statins in Diabetes Misses Primary Endpoint: EMPATHY
Among Japanese patients with diabetes, warding off a first cardiovascular or renal event was not better with statins and a low versus standard LDL-C goal, but stroke risk was lessened.Medscape Medical News
Source: Medscape Medical News Headlines - April 10, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

In-hospital mortality and morbidity of pediatric scoliosis surgery in Japan: Analysis using a national inpatient database
Several previous reports have elucidated the mortality and incidence of complications after pediatric scoliosis surgery using nationwide databases. However, all of these studies were conducted in North America. Hence, this study aimed to identify the incidence and risk factors for in-hospital mortality and morbidity in pediatric scoliosis surgery, utilizing the Diagnosis Procedure Combination database, a national inpatient database in Japan. We retrospectively extracted data for patients aged less than 19 years who were admitted between 01 June 2010 and 31 March 2013 and underwent scoliosis surgery with fusion. The primar...
Source: Medicine - April 1, 2018 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Desirable Low-Density Lipoprotein Cholesterol Levels for Preventing Stroke Recurrence Clinical Sciences
Conclusions—The composite risk of stroke and transient ischemic attack reduced in the postrandomized LDL cholesterol level of 80 to 100 mg/dL after adjusting for statin usage.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00221104.
Source: Stroke - March 26, 2018 Category: Neurology Authors: Naohisa Hosomi, Kazuo Kitagawa, Yoji Nagai, Yoko Nakagawa, Shiro Aoki, Tomohisa Nezu, Tatsuo Kagimura, Hirofumi Maruyama, Hideki Origasa, Kazuo Minematsu, Shinichiro Uchiyama, Masayasu Matsumoto Tags: Lipids and Cholesterol, Secondary Prevention, Treatment Original Contributions Source Type: research

The National Integrated Project for Prospective Observation of Non-communicable Disease and its Trends in the Aged 2010 (NIPPON DATA2010): Objectives, Design, and Population Characteristics.
CONCLUSIONS: We established NIPPON DATA2010 as a cohort study on a representative general Japanese population that covers all of Japan. PMID: 29503381 [PubMed - in process]
Source: Journal of Epidemiology - March 7, 2018 Category: Epidemiology Tags: J Epidemiol Source Type: research

Evaluation of Lenticulostriate Arteries Changes by 7 T Magnetic Resonance Angiography in Type 2 Diabetes.
CONCLUSION: In spite of the prevalence of SVD being similar, structural changes and decreased signal intensity of LSA were highly detected in diabetic subjects compared with non-diabetic controls, suggesting that 7 T MRA enables us to determine LSA impairment prior to the development of SVD. Early detection of LSA impairment allows us earlier interventions aimed at the prevention of atherosclerotic events. PMID: 29503412 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - March 6, 2018 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Registry of Japanese patients with atrial fibrillation focused on anticoagulant therapy in the new era: The RAFFINE registry study design and baseline characteristics.
CONCLUSION: The RAFFINE registry at baseline described the current status of anticoagulation therapy in Japan and long-term follow-up data will identify how outcomes vary between stratified groups in patients with AF in the DOAC era (UMIN Clinical Trials Registry UMIN000009617). PMID: 29502944 [PubMed - as supplied by publisher]
Source: Journal of Cardiology - March 1, 2018 Category: Cardiology Authors: Miyazaki S, Miyauchi K, Hayashi H, Tanaka R, Nojiri S, Miyazaki T, Sumiyoshi M, Suwa S, Nakazato Y, Urabe T, Hattori N, Daida H Tags: J Cardiol Source Type: research

Carotid atherosclerosis and the association between nocturnal blood pressure dipping and cardiovascular events
The impact of a nondipping blood pressure (BP) pattern, defined as (awake systolic BP – sleep systolic BP)/awake systolic BP < 0.1, on cardiovascular events in populations with different degrees of carotid atherosclerosis is uncertain. The authors hypothesized that a nondipping BP pattern would show differential predictive power for cardiovascular events, including total cardiovascular death, sudden death, nonfatal cardiovascular events, and nonfatal stroke, between populations with and without carotid atherosclerosis. To test this hypothesis, the authors analyzed 493 patients (mean age 67.9 years, 47.5% men) from ...
Source: The Journal of Clinical Hypertension - February 16, 2018 Category: Cardiology Authors: Praew Kotruchin, Satoshi Hoshide, Kazuomi Kario Tags: ORIGINAL PAPER Source Type: research

Outcome of Acute Ischemic Stroke after the Treatment with Edaravone and 0.6 Mg/Kg Alteplase in Japanese Patients with Diabetes
We investigated how diabetes mellitus (DM) affects the outcome of acute ischemic stroke (AIS), comparing with the outcomes in those who had hypertension (HT) and atrial fibrillation (AF).
Source: Journal of Stroke and Cerebrovascular Diseases - January 18, 2018 Category: Neurology Authors: Norio Tanahashi, Takenori Yamaguchi, Hideto Awano, Hiroaki Matsuda Source Type: research

Glucosuria and all-cause mortality among general screening participants
ConclusionDipstick glucosuria significantly affected mortality in Japanese community-based screening participants.
Source: Clinical and Experimental Nephrology - January 12, 2018 Category: Urology & Nephrology Source Type: research

A New Form of This Miracle Nutrient Is 8 Times More Powerful …
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Source: Al Sears, MD Natural Remedies - January 3, 2018 Category: Complementary Medicine Authors: Francisco Cabrera Tags: Nutrition antioxidants CoQ10 ubiquinol Source Type: news

Uric Acid Is a Strong Risk Marker for Developing Hypertension From PrehypertensionNovelty and Significance Hyperuricemia and Prehypertension
Prehypertension frequently progresses to hypertension, a condition associated with high morbidity and mortality from cardiovascular diseases and stroke. However, the risk factors for developing hypertension from prehypertension remain poorly understood. We conducted a retrospective cohort study using the data from 3584 prehypertensive Japanese adults (52.1±11.0 years, 2081 men) found to be prehypertensive in 2004 and reexamined in 2009. We calculated the cumulative incidences of hypertension over 5 years, examined risk factors, and calculated odds ratios (ORs) for developing hypertension after adjustments for age, sex, bo...
Source: Hypertension - December 13, 2017 Category: Cardiology Authors: Masanari Kuwabara, Ichiro Hisatome, Koichiro Niwa, Shigeko Hara, Carlos A. Roncal-Jimenez, Petter Bjornstad, Takahiko Nakagawa, Ana Andres-Hernando, Yuka Sato, Thomas Jensen, Gabriela Garcia, Bernardo Rodriguez-Iturbe, Minoru Ohno, Miguel A. Lanaspa, Rich Tags: Cardiovascular Disease, Epidemiology, Risk Factors, High Blood Pressure, Hypertension Original Articles Source Type: research