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Condition: Hydrocephalus

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Total 527 results found since Jan 2013.

Factors associated with poor outcome for aneurysmal subarachnoid haemorrhage in a series of 334 patients
Conclusions Outcome of aneurysmal subarachnoid haemorrhage was related to age, sex, clinical status at admission to the stroke unit, imaging findings according to the Fisher scale, blood pressure, glycaemia and such complications as electrolyte disturbances, hydrocephalus, rebleeding, and multiplex rebleeding.
Source: Neurologia - February 16, 2017 Category: Neurology Source Type: research

Management of aneurysmal subarachnoid hemorrhage: State of the art and future perspectives.
CONCLUSIONS: Even though no single pharmacological agent or treatment protocol has been identified, the main therapeutic interventions remain ineffective and limited to the manipulation of systemic blood pressure, alteration of blood volume or viscosity, and control of arterial dioxide tension. PMID: 28217390 [PubMed - in process]
Source: Surgical Neurology International - February 23, 2017 Category: Neurosurgery Tags: Surg Neurol Int Source Type: research

Reversed aqueductal cerebrospinal fluid net flow in idiopathic normal pressure hydrocephalus
ConclusionsINPH patients present hyperdynamic flow with increased velocity and volume both in systole and diastole phase. Degree of rising in diastole phase exceeds that of systole phase. The resulting reversal of netflow direction may play a key role in the occurrence of ventriculomegaly in iNPH patients.
Source: Acta Neurologica Scandinavica - February 28, 2017 Category: Neurology Authors: L. K. Yin, J. J. Zheng, L. Zhao, X. Z. Hao, X. X. Zhang, J. Q. Tian, K. Zheng, Y. M. Yang Tags: ORIGINAL ARTICLE Source Type: research

Effect of Admission Hyperglycemia on 6-Month Functional Outcome in Patients with Spontaneous Cerebellar Hemorrhage.
CONCLUSIONS To the best of our knowledge, this is the first study focusing on the relationship between hyperglycemia and long-term functional outcome after CH. The study combined with previous pertinent reports definitely indicates the poor effect of hyperglycemia on both supra- and infratentorial ICH independent of hemorrhage site. Therefore, further controlled trials are urgently needed to evaluate the benefits of glucose-lowing treatment. PMID: 28273059 [PubMed - in process]
Source: Medical Science Monitor - March 9, 2017 Category: Research Tags: Med Sci Monit Source Type: research

Successful delayed coiling of a ruptured growing distal posterior cerebral artery mycotic aneurysm.
Abstract Intracranial infectious aneurysm (IIA) is a rare form of cerebrovascular malformation for which obliteration may be undertaken after rupture or non-response to targeted antibiotic therapy. We discuss the case of a 19-year-old man who presented with acute neurologic decline (Glasgow Coma Scale of 8) and endocarditis. CT images demonstrated subarachnoid haemorrhage, hydrocephalus and a mycotic aneurysm on the left posterior cerebral artery. Conservative management was initially decided due to the high risk of stroke and hemianopia. However, it was then escalated to endovascular treatment because of increase...
Source: Neuro-Chirurgie - March 6, 2017 Category: Neurosurgery Authors: Champeaux C, Walker N, Derwin J, Grivas A Tags: Neurochirurgie Source Type: research

Cerebral Developmental Venous Anomaly- Preventing stroke in acute sinus thrombosis?
A 14 year old boy with no significant medical history presented with progressively worsening headache for 3 weeks, followed by acute encephalopathy and signs of raised intracranial pressure (ICP) including hypertension and bradycardia. CT head showed a large right transverse/sigmoid sinus thrombus and obstructive hydrocephalus. He underwent an urgent external ventricular drain placement.MRI demonstrated a large right transverse/sigmoid sinus thrombus, large bilateral cerebellar developmental venous anomalies (DVAs) and obstructive hydrocephalus.
Source: Pediatric Neurology - March 31, 2017 Category: Neurology Authors: Ajay Goenka, William Gomes, Jules Beal Tags: Visual Diagnosis Source Type: research

International Survey of Critically Ill Children With Acute Neurologic Insults: The Prevalence of Acute Critical Neurological Disease in Children: A Global Epidemiological Assessment Study*
Conclusions: Neurologic insults are a significant pediatric international health issue. They are frequent and contribute substantial morbidity and mortality. These data suggest a need for an increased focus on acute critical neurologic diseases in infants and children including additional research, enhanced availability of clinical resources, and the development of new therapies.
Source: Pediatric Critical Care Medicine - April 1, 2017 Category: Pediatrics Tags: Feature Articles Source Type: research

A Rare Case of Central Nervous System Tuberculosis Presenting as Transient Splenial Lesion: Case Report and Literature Review (P1.320)
Conclusions:Based on literature review, the transient splenial lesion of corpus callosum has never been reported in patients with CNS tuberculosis. The mechanisms underlying transient splenial lesions may due to intramyelinic edema and inflammatory cell infiltration. This hypothesis supported by the MR spectroscopy findings in our patient. Since early diagnosis and treatment can reduce mortality and morbidity, patients with isolated splenial lesion warrant diagnostic tests for CNS tuberculosis.Study Supported by:The authors report no disclosures relevant to the manuscript.Disclosure: Dr. Wu has nothing to disclose. Dr. Che...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Wu, J.-W., Chen, S. Tags: Autoimmunity with Infection, Syphilis, Lyme, Tuberculosis, and other Bacteria Source Type: research

Elevated ventricular CSF lactate within the first week after aneurysmal subarachnoid hemorrhage is associated with poor outcome (P5.068)
Conclusions:Elevated CSF lactate drawn within the first week of hospitalization following aSAH correlates with outcome. Larger prospective studies are needed to test the validity of this data for predicting outcome and for understanding the pathophysiologic mechanisms.Study Supported by: No funding was received for this study.Disclosure: Dr. Renfrow has nothing to disclose. Dr. Wilson has nothing to disclose. Dr. Arnel has nothing to disclose. Dr. Wolfe has nothing to disclose. Dr. Datar has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Renfrow, J., Wilson, T., Arnel, M., Wolfe, S., Datar, S. Tags: Neurocritical Care: Subarachnoid Hemorrhage Source Type: research

Cerebral Developmental Venous Anomaly —Does it Prevent Stroke in Acute Sinus Thrombosis?
This 14-year-old boy developed progressively severe headache for three  weeks followed by acute encephalopathy and signs of increased intracranial pressure with systemic hypertension and bradycardia. Computed tomography head showed a large right transverse/sigmoid sinus thrombus and obstructive hydrocephalus (Figure). He underwent an urgent external ventricular drain placement. Magnetic resonance imaging demonstrated a large right transverse/sigmoid sinus thrombus, large bilateral cerebellar developmental venous anomalies (DVAs), and obstructive hydrocephalus.
Source: Pediatric Neurology - March 31, 2017 Category: Neurology Authors: Ajay Goenka, William Gomes, Jules C. Beal Tags: Visual Diagnosis Source Type: research

Increased Plasma Galectin-3 Preceding the Development of Delayed Cerebral Infarction and Eventual Poor Outcome in Non-Severe Aneurysmal Subarachnoid Hemorrhage
This study included 83 consecutive patients diagnosed with aneurysmal SAH of resuscitated World Federation of Neurological Surgeons (WFNS) grades 1 –3. Plasma galectin-3 levels were once measured on days 1–3 (the day after clipping or coiling). Fifteen patients had poor outcomes, which were associated with increasing age, female, pre-onset morbidity, worse WFNS grade, modified Fisher computed tomography scale, acute hydrocephalus, and highe r galectin-3 levels compared with good outcomes. Multivariate analyses revealed that plasma galectin-3 was an independent determinant for poor outcome (odds ratio, 3.08; 95% confide...
Source: Translational Stroke Research - August 22, 2017 Category: Neurology Source Type: research

Radiofrequency saturation induced bias in aqueductal cerebrospinal fluid flow quantification obtained using two ‐dimensional cine phase contrast magnetic resonance imaging
ConclusionThis work shows the extent of bias in cerebrospinal fluid flow quantification due to radiofrequency saturation effects. This clinical relevance of this error was presented with respect to shunt responsiveness among normal pressure hydrocephalus patients. Magn Reson Med, 2017. © 2017 International Society for Magnetic Resonance in Medicine.
Source: Magnetic Resonance in Medicine - August 22, 2017 Category: Radiology Authors: Sudarshan Ragunathan, James G. Pipe Tags: Full Paper Source Type: research

Radiofrequency saturation induced bias in aqueductal cerebrospinal fluid flow quantification obtained using two-dimensional cine phase contrast magnetic resonance imaging.
CONCLUSION: This work shows the extent of bias in cerebrospinal fluid flow quantification due to radiofrequency saturation effects. This clinical relevance of this error was presented with respect to shunt responsiveness among normal pressure hydrocephalus patients. Magn Reson Med, 2017. © 2017 International Society for Magnetic Resonance in Medicine. PMID: 28833454 [PubMed - as supplied by publisher]
Source: Magnetic Resonance in Medicine - August 22, 2017 Category: Radiology Authors: Ragunathan S, Pipe JG Tags: Magn Reson Med Source Type: research

Readmission After Aneurysmal Subarachnoid Hemorrhage Clinical Sciences
Conclusions—In this national analysis, readmission was primarily attributable to new medical complications in patients with greater comorbidities and severity of SAH rather than exacerbation of complications from the SAH hospitalization. Additionally, hospital readmission rates did not correlate with other established quality metrics. Therefore, readmission may be a suboptimal quality indicator in the SAH population.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Hormuzdiyar H. Dasenbrock, Frederico Angriman, Timothy R. Smith, William B. Gormley, Kai U. Frerichs, M. Ali Aziz-Sultan, Rose Du Tags: Complications, Mortality/Survival, Quality and Outcomes, Cerebral Aneurysm Original Contributions Source Type: research

Quantitative analysis of cerebrospinal fluid dynamics at phase contrast cine-MRI: predictivity of neurosurgical "Shunt" responsiveness in patients with idiopathic normal pressure hydrocephalus.
CONCLUSIONS: ACSV is useful to stratify patients with NPH after surgery (improved /not improved) suggesting to proceed with serial ACSV measurements before deciding treatment. PMID: 28869371 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgical Sciences - September 6, 2017 Category: Neurosurgery Tags: J Neurosurg Sci Source Type: research