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Condition: Heart Failure
Education: Study
Procedure: Heart Valve Surgery

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Total 258 results found since Jan 2013.

Clinical Leaflet Thrombosis in Transcatheter and Surgical Bioprosthetic Aortic Valves by Four-Dimensional Computed Tomography
ConclusionsOne-third of patients with clinical or echocardiographic indications suggestive of leaflet thrombosis were found to have evidence of leaflet thrombosis using 4DCT. This allowed tailored anticoagulation therapy with resolution of the thrombus in most patients and avoiding unnecessary anticoagulation in the remaining two-thirds of patients.Visual Abstract
Source: The Annals of Thoracic Surgery - November 16, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research

Neutrophil-to-lymphocyte ratio predicts heart failure readmissions and outcomes in patients undergoing transcatheter aortic valve replacement.
CONCLUSION: NLR predicts all-cause mortality, MACE, and HF hospitalization 1 year after TAVR. NLR with TAVR risk score improved predictability for MACE. Further studies for prognostication using NLR are warranted. PMID: 30595282 [PubMed - in process]
Source: Indian Heart J - December 1, 2018 Category: Cardiology Authors: Khalil C, Pham M, Sawant AC, Sinibaldi E, Bhardwaj A, Ramanan T, Qureshi R, Khan S, Ibrahim A, Gowda SN, Pomakov A, Sadawarte P, Lahoti A, Hansen R, Baldo S, Colern G, Pershad A, Iyer V Tags: Indian Heart J Source Type: research

Incidence and in-hospital Safety Outcomes of Patients undergoing Percutaneous Mitral Valve Edge-to-Edge Repair Using MitraClip ® - 5 year German national patient sample including 13,575 implants.
CONCLUSIONS: MitraClip® implantations increased markedly 5.4-fold between 2011 and 2015, with a constant in-hospital mortality and MACCE rate. Our data indicate that edge-to-edge mitral valve repair in MitraClip® technique has acceptable in-hospital safety outcomes in a real world scenario. PMID: 30666965 [PubMed - as supplied by publisher]
Source: EuroIntervention - January 24, 2019 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research

Short-Term and Long-Term Outcomes of Patients Undergoing Urgent Transcatheter Aortic Valve Replacement Under a Minimalist Strategy.
CONCLUSIONS: Urgent minimalist TAVR can be safely performed with favorable in-hospital outcomes, while increased 30-day and 1-year mortality rates suggest the importance of appropriate diagnosis and timely treatment of severe aortic stenosis. PMID: 30700628 [PubMed - in process]
Source: The Journal of Invasive Cardiology - February 2, 2019 Category: Cardiology Tags: J Invasive Cardiol Source Type: research

Scientists discover new type of immune cells that are essential for forming heart valves
UCLA researchers have identified for the first time the origin of an immune cell that plays a critical role in the formation of healthy heart valves. The findings could pave the way for new treatments for heart valve disorders, which can be caused by congenital defects, aging or disease.Their study, led by Dr. Atsushi “Austin” Nakano, a UCLA associate professor of molecular, cell and developmental biology and member of theEli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA, was published in the journal Developmental Cell.Building on previous research by Nakano, which showed that the embr...
Source: UCLA Newsroom: Health Sciences - February 21, 2019 Category: Universities & Medical Training Source Type: news

Current status and future perspective of structural heart disease intervention.
Abstract Valvular heart diseases are one of the most frequent causes for heart failure. Degenerative diseases of the aortic and mitral valve as well as a dysfunctional tricuspid valve disease result in a worse clinical outcome if severe. Minimal-invasive, surgical and/or catheter-based structural heart disease (SHD) interventions have recently seen a dramatic increase. Transcatheter aortic valve implantation (TAVI) for severe aortic stenosis (AS) is a disruptive technology, and next generation devices and careful patient selection will minimize limitations of TAVI such as paravalvular leak, conductance disturbance...
Source: Journal of Cardiology - April 3, 2019 Category: Cardiology Authors: Tabata N, Sinning JM, Kaikita K, Tsujita K, Nickenig G, Werner N Tags: J Cardiol Source Type: research

Prognostic value of left atrial strain in patients with moderate asymptomatic mitral regurgitation
AbstractFor patients with asymptomatic mitral regurgitation (MR), the criteria identifying the groups at higher-risk and their clinical outcome are still uncertain. Therefore, in these patients, optimal time of surgery remains controversial. The purpose of this study was to compare left atrial (LA) strain to other echocardiographic left ventricular (LV) and LA parameters for the prediction of cardiovascular outcomes in patients with moderate asymptomatic MR. We enrolled 395 patients with primary degenerative moderate asymptomatic MR. Exclusion criteria were: history of atrial fibrillation, myocardial infarction, heart fail...
Source: The International Journal of Cardiovascular Imaging - April 9, 2019 Category: Radiology Source Type: research

Outcome Of Patients Undergoing Transcatheter Implantation Of Aortic Valve With Previous Mitral Valve Prosthesis (OPTIMAL STUDY)
ConclusionsTAVR in patients with a previous mitral prosthesis appears safe and feasible, with good hemodynamic results at 30-day and at longer term follow-up.
Source: Canadian Journal of Cardiology - April 16, 2019 Category: Cardiology Source Type: research

Determinants of long-term outcome of repaired pulmonary valve stenosis
ConclusionsGood long-term outcome can be expected after PVS repair, but complications and the need for reintervention may appear. Older age and the presence of cyanosis at PVS repair emerged as predictors of cardiovascular complications and identified a population that may merit stricter control.ResumenIntroducción y objetivosAunque la estenosis de la válvula pulmonar (EVP) se considera una cardiopatía congénita de bajo riesgo, se ha descrito la aparición de complicaciones y necesidad de reintervenir durante el seguimiento. Los objetivos del estudio fueron evaluar los resultados a largo plazo de la EVP reparada e iden...
Source: Revista Espanola de Cardiologia - May 24, 2019 Category: Cardiology Source Type: research

Sex-Based Differences in Outcomes After Mitral Valve Surgery for Severe Ischemic Mitral Regurgitation: From the Cardiothoracic Surgical Trials Network
ConclusionsWomen with SIMR displayed different echocardiographic features and experienced higher mortality and worse QOL after MV surgery than men. There were no significant differences in the degree of reverse LV remodeling between sexes. (Comparing the Effectiveness of Repairing Versus Replacing the Heart's Mitral Valve in People With Severe Chronic Ischemic Mitral Regurgitation [Severe Ischemic Mitral Regurgitation]; NCT00807040)Central Illustration
Source: JACC: Heart Failure - May 29, 2019 Category: Cardiology Source Type: research

Mitral valve surgery with or without coronary bypass grafting: eight-year cohort study.
CONCLUSION: MVR+CABG compared to MVR patients had more comorbidities and greater operative risk, and were independently associated with higher operative mortality and composite morbidity, but not independently associated with higher long-term mortality. PMID: 31415499 [PubMed - in process]
Source: New Zealand Medical Journal - August 16, 2019 Category: General Medicine Tags: N Z Med J Source Type: research

Predictors of Unfavourable Outcomes in Children and Adolescents Submitted to Surgical Mitral Valvuloplasty Secondary to Chronic Rheumatic Heart Disease
Conclusion: The duration of vasoactive drug use is an independent predictor for unfavourable outcomes in the immed iate and late postoperative period, while residual mitral regurgitation was associated with reoperation, and both tricuspid regurgitation and pulmonary hypertension were associated with unfavourable outcomes.Resumo Fundamento: A plastia da valva mitral, em pacientes pedi átricos com cardiopatia reumática crônica, é superior à troca valvar e vem sendo utilizada com bons resultados. Objetivo: Identificar variáveis preditoras de desfecho desfavorável em crianças e adolescentes submetidos à valvoplastia m...
Source: Arquivos Brasileiros de Cardiologia - November 5, 2019 Category: Cardiology Source Type: research

Mitral Valve Repair in Young Rheumatic Patients
Conclusion: The duration of vasoactive drug use is an independent predictor for unfavourable outcomes in the immed iate and late postoperative period, while residual mitral regurgitation was associated with reoperation, and both tricuspid regurgitation and pulmonary hypertension were associated with unfavourable outcomes.Resumo Fundamento: A plastia da valva mitral, em pacientes pedi átricos com cardiopatia reumática crônica, é superior à troca valvar e vem sendo utilizada com bons resultados. Objetivo: Identificar variáveis preditoras de desfecho desfavorável em crianças e adolescentes submetidos à valvoplastia m...
Source: Arquivos Brasileiros de Cardiologia - November 5, 2019 Category: Cardiology Source Type: research

Current Role of the Total Artificial Heart in the Management of Advanced Heart Failure
AbstractThe total artificial heart (TAH) is a form of mechanical circulatory support that involves resection of the native ventricles followed by placement of a device that can restore total pulmonary and systemic flow. Given the increasing burden of congestive heart failure and cardiovascular disease, the number of people in need of cardiac replacement therapy will continue to grow. Despite aggressive efforts to expand the donor pool, the number of heart transplants in the United States (US) has plateaued at less than 3000 per year. In addition, there is increasing recognition of the long-term complications of current gen...
Source: Current Cardiology Reports - November 21, 2019 Category: Cardiology Source Type: research

Right ventricular mechanical pattern in patients undergoing mitral valve surgery: a predictor of post ‐operative dysfunction?
ConclusionsMVR induces a significant shift in the RV mechanical pattern. Advanced indices of RV mechanics are associated with invasively measured parameters of RV contractility and may predict post ‐operative RVD.
Source: ESC Heart Failure - March 28, 2020 Category: Cardiology Authors: M árton Tokodi, Endre Németh, Bálint K. Lakatos, Erika Kispál, Zoltán Tősér, Levente Staub, Kristóf Rácz, Ádám Soltész, Szabolcs Szigeti, Tamás Varga, János Gál, Béla Merkely, Attila Kovács Tags: Original Research Article Source Type: research