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Condition: Heart Failure
Education: Study
Procedure: Heart Valve Surgery

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Total 258 results found since Jan 2013.

Impact of flow, gradient, and left ventricular function on outcomes after transcatheter aortic valve replacement
ConclusionsIn patients undergoing TAVR, low flow was an independent predictor of 1‐year mortality and HF, and a stronger predictor than either low AVG or LVEF. Patients with low flow and preserved EF had increased mortality and HF at 1‐year, while those with low flow and reduced EF had outcomes similar to patients with normal flow.
Source: Catheterization and Cardiovascular Interventions - October 8, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Edward T. Carreras, Tsuyoshi Kaneko, Fernando Ramirez ‐Del Val, Marc P. Pelletier, Piotr S. Sobieszczyk, Deepak L. Bhatt, Pinak B. Shah Tags: VALVULAR AND STRUCTURAL HEART DISEASES Source Type: research

Long ‐term outcomes for different surgical strategies to treat left ventricular outflow tract obstruction in hypertrophic cardiomyopathy
ConclusionSeptal myectomy is a safe procedure resulting in symptomatic improvement in the majority of patients. The annual incidence of non‐fatal disease‐related complications after surgical treatment of LVOTO is relatively high. Patients who underwent MV replacements had poorer outcomes with less symptomatic benefit in spite of a similar reduction in LVOT gradients.
Source: European Journal of Heart Failure - November 16, 2017 Category: Cardiology Authors: Richard Collis, Oliver Watkinson, Constantinos O'Mahony, Oliver P. Guttmann, Antonis Pantazis, Maria Tome ‐Esteban, Victor Tsang, Venkatachalam Chandrasekaran, Christopher G.A. McGregor, Perry M. Elliott Tags: Research Article Source Type: research

Efficacy and Efficiency of Perioperative Stellate Ganglion Blocks in Cardiac Surgery: A Pilot Study
Nationally, postoperative atrial fibrillation (POAF) occurs in up to 40% of patients after coronary artery bypass grafting (CABG), 50% of patients after valve surgery, 64% of patients after mitral valve and CABG, and 49% after aortic valve replacement.1 Atrial fibrillation worsens a patient ’s hemodynamic status and increases the risk of congestive heart failure, embolic events, and longer intensive care unit stays, leading to increased patient morbidity and strain on financial resources. In the United States, POAF carries a higher risk of stroke, worsened survival, and an additional 4.9 days and $10,000 to $11,500 in hospital stay costs.
Source: Journal of Cardiothoracic and Vascular Anesthesia - November 20, 2017 Category: Anesthesiology Authors: Christopher W. Connors, Wendy Y. Craig, Scott A. Buchanan, Justin M. Poltak, James B. Gagnon, Craig S. Curry Tags: Letter to the Editor Source Type: research

Mitralign raises $10m
Mitralign, which is looking to commercialize its namesake mitral valve treatment and pursue regulatory nods for its Trialign tricuspid valve device, said it raised nearly $10 million. The $9.8 million funding, of a hoped-for $30.2 million, came from 19 unnamed investors beginning last September, the Tewksbury, Mass.-based company said in a regulatory filing. Mitralign raised a $40 million Series E round in May 2016. The Mitralign and Trialign devices are designed to use wire and catheters to implant polyester anchors within the annulus of the mitral and tricuspid valves. The anchors are then cinched together to reduce v...
Source: Mass Device - February 21, 2018 Category: Medical Devices Authors: Brad Perriello Tags: Funding Roundup Replacement Heart Valves Wall Street Beat Mitralign Inc. Source Type: news

Prevalence and Outcomes of Mitral Stenosis in Patients Undergoing Transcatheter Aortic Valve Replacement: Findings From the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapies Registry
Conclusions Approximately one-tenth of patients undergoing TAVR have concomitant MS. Severe MS is an independent predictor of 1-year adverse clinical outcomes following TAVR. The higher risk for long-term adverse events must be considered when evaluating patients with combined aortic stenosis and MS for TAVR.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - April 2, 2018 Category: Cardiology Authors: Joseph, L., Bashir, M., Xiang, Q., Yerokun, B. A., Matsouaka, R. A., Vemulapalli, S., Kapadia, S., Cigarroa, J. E., Zahr, F. Tags: Structural Source Type: research

Mata-Analysis Comparing Transcatheter Versus Surgical Treatment of Paravalvular Leaks
Percutaneous paravalvular leak (PVL) closure has emerged as a feasible alternative to redo valve surgery. However, comparative data on percutaneous and surgical treatment of PVL are scarce. We performed a systematic review and a meta-analysis of studies on percutaneous and surgical treatment of PVL. Of the 2267 studies screened, 22 eligible studies were analyzed. Primary endpoints were: technical success, 30-day mortality, stroke and length-of-stay. Secondary endpoints were: 1-year mortality, readmission for heart failure, reoperation, and symptomatic improvement at follow-up.
Source: The American Journal of Cardiology - April 19, 2018 Category: Cardiology Authors: Tatiana Busu, Fahad Alqahtani, Vinay Badhwar, Chris C. Cook, Charanjit S. Rihal, Mohamad Alkhouli Source Type: research

Meta-analysis Comparing Transcatheter and Surgical Treatments of Paravalvular Leaks
Percutaneous paravalvular leak (PVL) closure has emerged as a feasible alternative to redo valve surgery. However, comparative data on percutaneous and surgical treatment of PVL are scarce. We performed a systematic review and a meta-analysis of studies on percutaneous and surgical treatments of PVL. Of the 2,267 studies screened, 22 eligible studies were analyzed. Primary end points were technical success, 30-day mortality, stroke, and length of stay. Secondary end points were 1-year mortality, readmission for heart failure, reoperation, and symptomatic improvement at follow-up.
Source: The American Journal of Cardiology - April 19, 2018 Category: Cardiology Authors: Tatiana Busu, Fahad Alqahtani, Vinay Badhwar, Chris C. Cook, Charanjit S. Rihal, Mohamad Alkhouli Source Type: research

Prognosis of Cancer Patients with Aortic Stenosis Under Optimal Cancer Therapies and Conservative Cardiac Treatments.
Authors: Okura Y, Ishigaki S, Sakakibara S, Yumoto C, Hashitate M, Sekine C, Fujita T, Takayama T, Ozaki K, Sato N, Minamino T Abstract Aortic stenosis (AS) is a life-threatening comorbidity of cancer patients. Aortic valve replacement (AVR) should be considered for some cancer patients, but neither the characteristics nor prognosis under conservative therapy is well known.We searched our echocardiography log (years 2005-2014) for cancer patients with AS, and 92 patients (54% female) were included in the study. To compare the survival curves, 470 control patients without AS were selected from our cancer registry.Me...
Source: International Heart Journal - June 9, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

Neutrophil to Lymphocyte Ratio Predicts Heart Failure Readmissions and Outcomes in Patients Undergoing Transcatheter Aortic Valve Replacement
ConclusionNLR predicts all-cause mortality, MACE, and HF hospitalization 1-year post-TAVR. NLR with TAVR risk score improved predictability for MACE. Further studies for prognostication utilizing NLR are warranted.
Source: Indian Heart Journal - August 18, 2018 Category: Cardiology Source Type: research

Red Cell Distribution Width as a Prognostic Marker in Patients Undergoing Valve Surgery.
CONCLUSIONS: An elevated RDW is associated with a worse outcome following valve surgery. The predictive ability of the RDW, when assessed by the area under the ROC curve, improved the predictive ability of the EuroSCORE II calculator. PMID: 30207123 [PubMed - in process]
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Neutrophil-to-lymphocyte ratio predicts heart failure readmissions and outcomes in patients undergoing transcatheter aortic valve replacement
ConclusionNLR predicts all-cause mortality, MACE, and HF hospitalization 1 year after TAVR. NLR with TAVR risk score improved predictability for MACE. Further studies for prognostication using NLR are warranted.
Source: Indian Heart Journal - September 14, 2018 Category: Cardiology Source Type: research

Risk stratification and clinical outcomes after surgical pulmonary valve replacement
ConclusionPatients undergoing PVR at larger RV volumes had similar survival but more overall CAE. A larger study population with a longer follow-up will be required to determine if early PVR provides survival benefit in the long-term.
Source: American Heart Journal - October 4, 2018 Category: Cardiology Source Type: research

Clinical Outcomes of Mitral Valve Reoperations in the United States: An Analysis of the Society of Thoracic Surgeons National Database
ConclusionsDespite a high-risk patient profile, surgical outcomes of reoperative MVS were acceptable, particularly in elective cases with prior mitral valve surgery and without endocarditis.
Source: The Annals of Thoracic Surgery - October 24, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research

Clinical Outcomes of Mitral Valve Reoperations in the United States: An Analysis of the Society of Thoracic Surgeons National Database.
CONCLUSIONS: Despite a high-risk patient profile, surgical outcomes of reoperative MVS were acceptable, particularly in elective cases with prior mitral valve surgery and without endocarditis. PMID: 30365952 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - October 23, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Kilic A, Acker MA, Gleason TG, Sultan I, Vemulapalli S, Thibault D, Ailawadi G, Badhwar V, Thourani V, Kilic A Tags: Ann Thorac Surg Source Type: research