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Condition: Heart Failure
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Total 240 results found since Jan 2013.

Pharmacological and cardiovascular perspectives on the treatment of COVID-19 with chloroquine derivatives.
Abstract The novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19) and an ongoing severe pandemic. Curative drugs specific for COVID-19 are currently lacking. Chloroquine phosphate and its derivative hydroxychloroquine, which have been used in the treatment and prevention of malaria and autoimmune diseases for decades, were found to inhibit SARS-CoV-2 infection with high potency in vitro and have shown clinical and virologic benefits in COVID-19 patients. Therefore, chloroquine phosphate was first used in the treatment of COVID-19 in China. Later, under a lim...
Source: Acta Pharmacologica Sinica - September 22, 2020 Category: Drugs & Pharmacology Authors: Zhang XL, Li ZM, Ye JT, Lu J, Ye LL, Zhang CX, Liu PQ, Duan DD Tags: Acta Pharmacol Sin Source Type: research

Optimization of GRACE Risk Stratification by N-Terminal Pro-B-Type Natriuretic Peptide Combined with D-dimer in Patients with Non-ST-elevation Myocardial Infarction
We aimed to explore the utility of multiple biomarkers with GRACE risk stratification for non-ST-elevation myocardial infarction (NSTEMI). A total of 1357 patients diagnosed with NSTEMI were enrolled in this study at multiple medical centers in Tianjin, China. The outcomes were 1-year all-cause death and major adverse cardiac events (MACE: all-cause death, hospital admission for unstable angina, hospital admission for heart failure, non-fatal recurrent myocardial infarction, and stroke). C-index, NRI and IDI were calculated to verify that the biomarkers improve the predictive accuracy of the GRACE score.
Source: The American Journal of Cardiology - November 3, 2020 Category: Cardiology Authors: Peng-Ju Lu, Xiao-Wen Gong, Yin Liu, Feng-Shi Tian, Wen-Juan Zhang, Ying-Wu Liu, Zhu-Hua Yao, Ji-Xiang Wang, Peng Han, Ya-Nan Yang, Zhuang Cui, Jing Gao Source Type: research

Associations of Atrial Fibrillation Progression with Clinical Risk Factors and Clinical Prognosis: A report from the Chinese Atrial Fibrillation Registry Study
ConclusionsAF progression was common in its natural course. It was related to comorbidities and whether rhythm control strategies were used, and was associated with an increased risk of IS/SE and cardiovascular hospitalization.Clinical Trial RegistrationChinese Clinical Trial Registry ChiCTR ‐OCH‐13003729. URL:http://www.chictr.org.cn/showproj.aspx?proj=5831This article is protected by copyright. All rights reserved.
Source: Journal of Cardiovascular Electrophysiology - December 3, 2020 Category: Cardiology Authors: Wang ‐Yang Yang, Xin Du, Ameenathul M Fawzy, Liu He, Hong‐Wei Li, Jian‐Zeng Dong, Gregory Y.H. Lip, Chang‐Sheng Ma, The Chinese Atrial Fibrillation Registry Study Group Tags: ORIGINAL ‐ ELECTROPHYSIOLOGY Source Type: research

Association between use of amiodarone for non-valvular atrial fibrillation and patient survival: from the prospective China Atrial Fibrillation Registry.
CONCLUSIONS: Our study indicated that amiodarone use was not significantly associated with a lower risk of 1-year all-cause mortality compared with a non-AAD strategy in "real-world" patients with NVAF. PMID: 33273373 [PubMed - as supplied by publisher]
Source: Chinese Medical Journal - December 1, 2020 Category: General Medicine Authors: Hou XX, He L, Du X, Wang GH, Dong JZ, Ma CS Tags: Chin Med J (Engl) Source Type: research

Use of Cardiovascular Drugs for Primary and Secondary Prevention of Cardiovascular Disease Among Rural-Dwelling Older Chinese Adults
In conclusion, despite highly prevalent cardiovascular risk factors and CVDs, a fairly low proportion of the rural-dwelling older adults take CV medications for primary and secondary prevention. Notably, TCM products are among the most commonly used CV drugs. These results call for additional efforts to promote implementation of the evidence-based recommendations for prevention of CVDs in the primary care settings.
Source: Frontiers in Pharmacology - December 18, 2020 Category: Drugs & Pharmacology Source Type: research

Late-onset myocardial infarction and autoimmune haemolytic anaemia in a COVID-19 patient without respiratory symptoms, concomitant with a paradoxical increase in inflammatory markers: a case report
ConclusionsBoth complications occurred quite late after COVID-19 diagnosis and were probably precipitated by systemic inflammation, as indicated by a significant delayed increase in inflammatory markers, including interleukin-6 (IL-6).
Source: Journal of Medical Case Reports - December 18, 2020 Category: General Medicine Source Type: research

Effect of Family History of Atrial Fibrillation on Recurrence After Atrial Fibrillation Ablation: A Report from the Chinese Atrial Fibrillation Registry Study
ConclusionFAF is a risk factor for post ‐ablation AT recurrence. This is especially true in those with AF diagnosed at 50 years or younger.Clinical Trial Registration —URL:http://www.chictr.org.cn/showproj.aspx?proj=5831.Unique identifier: ChiCTR ‐OCH‐13003729.This article is protected by copyright. All rights reserved.
Source: Journal of Cardiovascular Electrophysiology - January 29, 2021 Category: Cardiology Authors: Zhuanzhuan Wu, Chao Jiang, Jingye Li, Jing Du, Yu Bai, Xueyuan Guo, Wei Wang, Songnan Li, Chenxi Jiang, Nian Liu, Ribo Tang, Rong Bai, Caihua Sang, Deyong Long, Xin Du, Changsheng Ma, Jianzeng Dong Tags: ORIGINAL ARTICLES Source Type: research

Associations of atrial fibrillation progression with clinical risk factors and clinical prognosis: A report from the Chinese Atrial Fibrillation Registry study
ConclusionAF progression was common in its natural course. It was related to comorbidities and whether rhythm control strategies were used, and was associated with an increased risk of IS/SE and cardiovascular hospitalization.
Source: Journal of Cardiovascular Electrophysiology - February 11, 2021 Category: Cardiology Authors: Wang ‐Yang Yang, Xin Du, Ameenathul M. Fawzy, Liu He, Hong‐Wei Li, Jian‐Zeng Dong, Gregory Y. H. Lip, Chang‐Sheng Ma, The Chinese Atrial Fibrillation Registry Study Group Tags: ORIGINAL – ELECTROPHYSIOLOGY Source Type: research

Effect of family history of atrial fibrillation on recurrence after atrial fibrillation ablation: A report from the Chinese Atrial Fibrillation Registry Study
ConclusionFAF is a risk factor for postablation AT recurrence. This is especially true in those with AF diagnosed at 50 years or younger.
Source: Journal of Cardiovascular Electrophysiology - February 10, 2021 Category: Cardiology Authors: Zhuanzhuan Wu, Chao Jiang, Jingye Li, Jing Du, Yu Bai, Xueyuan Guo, Wei Wang, Songnan Li, Chenxi Jiang, Nian Liu, Ribo Tang, Rong Bai, Caihua Sang, Deyong Long, Xin Du, Changsheng Ma, Jianzeng Dong Tags: ORIGINAL ARTICLES Source Type: research

Genes, Vol. 12, Pages 408: KLF15 Loss-of-Function Mutation Underlying Atrial Fibrillation as well as Ventricular Arrhythmias and Cardiomyopathy
Yang Min Zhang Atrial fibrillation (AF) represents the most common type of clinical cardiac arrhythmia and substantially increases the risks of cerebral stroke, heart failure and death. Accumulating evidence has convincingly demonstrated the strong genetic basis of AF, and an increasing number of pathogenic variations in over 50 genes have been causally linked to AF. Nevertheless, AF is of pronounced genetic heterogeneity, and the genetic determinants underpinning AF in most patients remain obscure. In the current investigation, a Chinese pedigree with AF as well as ventricular arrhythmias and hypertrophic cardiomyo...
Source: Genes - March 12, 2021 Category: Genetics & Stem Cells Authors: Ning Li Ying-Jia Xu Hong-Yu Shi Chen-Xi Yang Yu-Han Guo Ruo-Gu Li Xing-Biao Qiu Yi-Qing Yang Min Zhang Tags: Article Source Type: research

Efficacy and Safety of Xinyue Capsule for Coronary Artery Disease after Percutaneous Coronary Intervention: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
Evid Based Complement Alternat Med. 2021 Apr 8;2021:6695868. doi: 10.1155/2021/6695868. eCollection 2021.ABSTRACTTo evaluate the efficacy and safety of Xinyue capsule (XYC) in the treatment of coronary artery disease (CAD) after percutaneous coronary intervention (PCI), databases including MEDLINE, EMBASE (Ovid), PubMed, Google Scholar, Cochrane Central Register of Controlled Trials (CENTRAL), China National Knowledge Infrastructure database (CNKI), Wanfang, and VIP were searched to identify randomized controlled trials (RCTs) on XYC in CAD after PCI published before October 2020. Data extraction, methodological quality as...
Source: Evidence-based Complementary and Alternative Medicine - April 26, 2021 Category: Complementary Medicine Authors: Zhonghui Jiang Hua Qu Ying Zhang Fan Zhang Wenli Xiao Dazhuo Shi Zhuye Gao Keji Chen Source Type: research

Refining age stratum of the C < sub > 2 < /sub > HEST score for predicting incident atrial fibrillation in a hospital-based Chinese population
CONCLUSION: In a hospital-based Chinese population, by refining the age strata of the original C2HEST score, the mC2HEST score had significantly increased predictive accuracy and discriminative capability for incident AF. The clinical benefits of the application of novel mC2HEST score needs further validation in multiple settings.PMID:33975769 | DOI:10.1016/j.ejim.2021.04.014
Source: European Journal of Internal Medicine - May 12, 2021 Category: Internal Medicine Authors: Yan-Guang Li Jin Bai Gongbu Zhou Juan Li Yi Wei Lijie Sun Lingyun Zu Shuwang Liu Source Type: research