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Condition: Encephalitis
Infectious Disease: Pandemics

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Total 235 results found since Jan 2013.

Neurological Manifestations of Coronavirus Disease 2019: A Comprehensive Review and Meta-Analysis of the First 6 Months of Pandemic Reporting
Conclusions: The COVID-19 pandemic exerts a substantial neurologic burden which may have residual effects on patients and healthcare systems for years. Low quality evidence impedes the ability to accurately predict the magnitude of this burden. Robust studies with standardised screening and case definitions are required to improve understanding of this disease and optimise treatment of individuals at higher risk for neurologic sequelae.
Source: Frontiers in Neurology - August 12, 2021 Category: Neurology Source Type: research

SARS-CoV-2 Poorly Replicates in Cells of the Human Blood-Brain Barrier Without Associated Deleterious Effects
Various neurological symptoms have been associated to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection including headache, fever, anosmia, ageusia, but also, encephalitis, Guillain-Barre syndrome and ischemic stroke. Responsible for the current coronavirus disease (COVID-19) pandemic, SARS-CoV-2 may access and affect the central nervous system (CNS) by several pathways such as axonal retrograde transport or through interaction with the blood-brain barrier (BBB) or blood-cerebrospinal fluid (CSF) barrier. Here, we explored the molecular and cellular effects of direct SARS-CoV-2 infection of human BBB c...
Source: Frontiers in Immunology - July 27, 2021 Category: Allergy & Immunology Source Type: research

Neurologic aspects of coronavirus disease of 2019 infection
Purpose of review Central and peripheral nervous system manifestations of coronavirus disease 2019 (COVID-19) have been frequently reported and may cause significant morbidity and mortality. This review details the latest evidence on the neuropathogenesis and neurologic complications of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Recent findings Commonly reported neurologic complications include toxic-metabolic encephalopathy, acute cerebrovascular disorders, seizures, and anoxic-brain injury. These complications represent secondary injury due to COVID-19 related hypoxia, sepsis, hype...
Source: Current Opinion in Infectious Diseases - May 2, 2021 Category: Infectious Diseases Tags: CNS INFECTIONS: Edited by Adarsh Bhimraj Source Type: research

Demyelination as a result of an immune response in patients with COVID-19
AbstractThe coronavirus disease of 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus-2 (SARS CoV-2), that already appeared as a global pandemic. Presentation of the disease often includes upper respiratory symptoms like dry cough, dyspnea, chest pain, and rhinorrhea that can develop to respiratory failure, needing intubation. Furthermore, the occurrence of acute and subacute neurological manifestations such as stroke, encephalitis, headache, and seizures are frequently stated in patients with COVID-19. One of the reported neurological complications of severe COVID-19 is the demolition of the my...
Source: Acta Neurologica Belgica - May 2, 2021 Category: Neurology Source Type: research

One-Third of COVID-19 Survivors May Develop a Neuropsychiatric Disorder Within Months of Infection
One-third of individuals diagnosed with COVID-19 developed a psychiatric or neurological problem within six months of their diagnosis, according to astudy published Tuesday inThe Lancet Psychiatry. The prevalence of a post-COVID neurologic or psychiatric diagnosis was even greater among individuals with severe illness who had required hospitalization.“Given the size of the pandemic and the chronicity of many of the diagnoses and their consequences (for example, dementia, stroke, and intracranial hemorrhage), substantial effects on health and social care systems are likely to occur,” wrote Maxime Taque, Ph.D., of the Un...
Source: Psychiatr News - April 7, 2021 Category: Psychiatry Tags: anxiety COVID-19 electronic health records hospitalizations mood disorders neuropsychiatric disorders The Lancet Psychiatry Source Type: research

Neurological Complications of the COVID-19 Pandemic: What Have We Got So Far?
Adv Exp Med Biol. 2021;1321:21-31. doi: 10.1007/978-3-030-59261-5_2.ABSTRACTThe recently emerged coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of COVID-19, is the newest threat to human health. It has already infected more than 54.5 million people worldwide, currently leading to more than 1.3 million deaths. Although it causes a mild flu-like disease in most patients, lethality may increase to more than 20% in elderly subjects, especially in those with comorbidities, like hypertension, diabetes, or lung and cardiac disease, and the mechanisms are still elusive. Common symp...
Source: Advances in Experimental Medicine and Biology - March 3, 2021 Category: Research Authors: Isabelle Pastor Bandeira Marco Ant ônio Machado Schlindwein Leticia Caroline Breis Jean Pierre Schatzmann Peron Marcus Vin ícius Magno Gonçalves Source Type: research

COVID-19 and Neurology - An Emerging Association
CONCLUSIONS: Presentation of COVID-19 with neurological features is not uncommon, and these patients should be tested earlier to help in the prevention of transmission, early diagnosis, and management.PMID:33602080 | DOI:10.2174/1871526521666210218202226
Source: Infectious Disorders Drug Targets - February 19, 2021 Category: Infectious Diseases Authors: Amit Gupta Prakrati Yadav Deepak Kumar Source Type: research

COVID-19 and Neurology - An Emerging Association.
CONCLUSIONS: Presentation of COVID-19 with neurological features is not uncommon, and these patients should be tested earlier to help in the prevention of transmission, early diagnosis, and management. PMID: 33602080 [PubMed - as supplied by publisher]
Source: Infectious Disorders Drug Targets - February 18, 2021 Category: Infectious Diseases Authors: Gupta A, Yadav P, Kumar D Tags: Infect Disord Drug Targets Source Type: research

Presentations and mechanisms of CNS disorders related to COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the coronavirus disease 2019 (COVID-19) pandemic. In addition to severe respiratory symptoms, there are a growing number of reports showing a wide range of CNS complications in patients with COVID-19. Here, we review the literature on these complications, ranging from nonspecific symptoms to necrotizing encephalopathies, encephalitis, myelitis, encephalomyelitis, endotheliitis, and stroke. We postulate that there are several different mechanisms involved in COVID-19–associated CNS dysfunction, particularly activation of inflammatory and thro...
Source: Neurology Neuroimmunology and Neuroinflammation - December 11, 2020 Category: Neurology Authors: Bodro, M., Compta, Y., Sanchez-Valle, R. Tags: Other cerebrovascular disease/ Stroke, Encephalitis, COVID-19 Views [amp ] Reviews Source Type: research

Neurological Associations of COVID-19 —Do We Know Enough: A Tertiary Care Hospital Based Study
This study will discuss the detailed systematically evaluated clinical profile and relevant investigations and outcome of 14 laboratory confirmed SARS-CoV-2 positive patients presenting with neurological signs and symptoms. The patients were further categorized into confirmed, probable, and possible neurological associations. The probable association was found in meningoencephalitis (n = 4), stroke (n = 2), Guillain-Barré syndrome (n = 1), and anosmia (n = 1). The other six patients had coexisting neurological diseases with SARS-CoV-2. One patient with a large artery stroke succumbed to the illness due to respiratory comp...
Source: Frontiers in Neurology - November 24, 2020 Category: Neurology Source Type: research

Neurological manifestations of COVID-19: available evidences and a new paradigm
AbstractThe recent pandemic outbreak of coronavirus is pathogenic and a highly transmittable viral infection caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2). In this time of ongoing pandemic, many emerging reports suggested that the SARS-CoV-2 has inimical effects on neurological functions, and even causes serious neurological damage. The neurological symptoms associated with COVID-19 include headache, dizziness, depression, anosmia, encephalitis, stroke, epileptic seizures, and Guillain-Barre syndrome along with many others. The involvement of the CNS may be related with poor prognosis and disease wo...
Source: Journal of NeuroVirology - August 23, 2020 Category: Neurology Source Type: research