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Condition: Dementia
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Total 430 results found since Jan 2013.

Burden of Silent Cerebrovascular Disease and Not Acute Infarct Characteristics Determine Post-Stroke Cognitive Impairment, Both in Small Vessel and Large Vessel Strokes (P5.222)
CONCLUSIONS:Our results highlight the importance of silent cerebral ischemia as a key determinant of PSCI. Though acute infarct may lead to acute decline in cognition, WMH is the likely factor determining the severity of cognitive impairment. Optimization of vascular risk factors in the general population might play an important role in reducing the prevalence of PSCI.Study Supported by:National Neuroscience Institute, SingaporeDisclosure: Dr. Poh has nothing to disclose. Dr. Poh has nothing to disclose. Dr. Ng has nothing to disclose. Dr. Marmin has nothing to disclose. Dr. Ho has nothing to disclose. Dr. Zainal has nothi...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Poh, Y. Y., Poh, Y. Q. J., Ng, A., Marmin, M., Ho, Y. L., Zainal, H., Kandiah, N. Tags: Aging, Dementia, and Cognitive and Behavioral Neurology: Cerebrovascular Ischemia, Metabolism, and Epidemiology Source Type: research

Increasing Skeletal Muscle Mass Could Prevent Stroke (P1.177)
Conclusion: High SMM group had low WMC/SI, especially in men. Increased SMM by muscle strengthening exercise may prevent stroke.Disclosure: Dr. Minn has nothing to disclose. Dr. Suk has nothing to disclose. Dr. Koh has nothing to disclose. Dr. Hwang has nothing to disclose. Dr. Park has nothing to disclose. Dr. Lee has nothing to disclose. Dr. Song has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Minn, Y. K., Suk, S. H., Koh, I. S., Hwang, S.-H., Park, J. H., Lee, J. H., Song, H. Tags: Cerebrovascular Disease: Risk Factors and Prevention Source Type: research

Structural brain network measures are superior to vascular burden scores in predicting early cognitive impairment in post stroke patients with small vessel disease
ConclusionsBrain network measures, but not the SVD score, are significantly correlated with cognition in post-stroke SVD patients. Mediation analysis showed that the cerebral vascular lesions produce cognitive dysfunction by interfering with the structural brain network in SVD patients. The brain network measures may be regarded as direct and independent surrogate markers of cognitive impairment in SVD.
Source: NeuroImage: Clinical - February 5, 2019 Category: Radiology Source Type: research

Pre-Existing Dementia in Octagenerians with Acute Ischemic Stroke
To investigate the prevalance of pre-existing dementia and vascular risk factors in hospitalized octaganerians with acute ischemic stroke. Study subjects were selected from neurology inpatient records of Haseki Research and Education Hospital and included inpatients over 80 years old with acute ischemic stroke between January 2010 and July 2013. Their medical records were reviewed, and the rates of hypertension, diabetes mellitus, atrial fibrillation and dementia were calculated.
Source: Neurobiology of Aging - December 10, 2013 Category: Neuroscience Authors: Birgul Bastan, Sefer Gunaydin, Belgin P. Balci, Hurtan Ozacar, Ozlem Cokar, Feriha Ozer Tags: Meeting Abstracts Source Type: research

Early Life Risk Factors for Stroke and Cognitive Impairment
Abstract Cerebrovascular disease may present in later life with stroke or cognitive impairment and dementia, or may be silent, with changes seen incidentally on imaging or pathology. Midlife vascular risk factors such as hypertension, smoking and diabetes are well recognised. However, factors from much earlier in life may contribute to later vascular risk. In this commentary, we outline the importance of considering the whole life course in the development of cerebrovascular disease. We consider mainly factors from childhood, childhood intelligence test scores, education and socioeconomic status, which have been s...
Source: Current Epidemiology Reports - July 4, 2015 Category: Epidemiology Source Type: research

NIH Launches New Public Health Campaign
A growing body of scientific evidence indicates that uncontrolled high blood pressure is not only the leading cause of stroke but may also be linked to cognitive decline and dementia. Today, the National Institutes of Health’s (NIH) National Institute of Neurological Disorders and Stroke (NINDS) is launching a public health education campaign called Mind Your Risks.
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - February 2, 2016 Category: Neurology Source Type: news

Cognitive Impairment, Asymptomatic Carotid Stenosis and Arterial Hypertension in Adult Persons without a History of Stroke: A Population-Based Epidemiological Study (P5.216)
CONCLUSIONS: This data suggest that persons with vascular risk factors such as ACS蠅50% and systolic AH might have a higher risk of CI. Study Supported by: Medical Faculty, Trakia University, Stara Zagora, BulgariaDisclosure: Dr. Mineva has nothing to disclose. Dr. Talalaev has nothing to disclose. Dr. Proychev has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Mineva, P., Talalaev, D., Proychev, V. Tags: Aging, Dementia, and Cognitive and Behavioral Neurology: Epidemiology Source Type: research

Subclinical cerebrovascular disease inversely associates with learning ability: The NOMAS
Conclusions: White matter hyperintensities, a marker of cerebral small vessel disease, may have an impact on learning slope. This suggests that verbal learning performance can be incorporated into neuropsychological measures for vascular cognitive impairment and that cerebrovascular disease discovered on imaging affects the ability to learn new information.
Source: Neurology - June 8, 2015 Category: Neurology Authors: Glazer, H., Dong, C., Yoshita, M., Rundek, T., Elkind, M. S. V., Sacco, R. L., DeCarli, C., Stern, Y., Wright, C. B. Tags: All Cerebrovascular disease/Stroke, Cognitive aging, Assessment of cognitive disorders/dementia ARTICLE Source Type: research

Executive Function Declines in the First 6 Months After a Transient Ischemic Attack or Transient Neurological Attack Clinical Sciences
Conclusions—Executive function declines during the first 6 months after TIA or TNA. Patients with an initial DWI lesion have persisting worse executive function than those without.
Source: Stroke - November 27, 2017 Category: Neurology Authors: Frank G. van Rooiȷ, Nicole O. Plaizier, Sarah E. Vermeer, Bozena M. Goraȷ, Peter J. Koudstaal, Edo Richard, Frank–Erik de Leeuw, Roy P.C. Kessels, Ewoud J. van Diȷk Tags: Cognitive Impairment, Transient Ischemic Attack (TIA) Original Contributions Source Type: research

Circulating inflammatory biomarkers are related to cerebrovascular disease in older adults
Conclusions Among older adults, increased circulating inflammatory biomarkers were associated with the presence of infarcts and microbleeds, WMH burden, and progression of WMH.
Source: Neurology Neuroimmunology and Neuroinflammation - November 14, 2018 Category: Neurology Authors: Gu, Y., Gutierrez, J., Meier, I. B., Guzman, V. A., Manly, J. J., Schupf, N., Brickman, A. M., Mayeux, R. Tags: All Imaging, All Immunology, All Cerebrovascular disease/Stroke, All Cognitive Disorders/Dementia, All epidemiology Article Source Type: research

Correlation Between Intracranial Arterial Calcification and Imaging of Cerebral Small Vessel Disease
Conclusion: Intracranial artery calcification is common in patients with ischemic cerebrovascular disease and the intracranial carotid artery is most frequently affected. Intracranial arterial calcifications might be associated with imaging markers of SVD and are highly correlated with WMHs, lacunes, and CMBs. Quantification of calcification on CT provides additional information on the pathophysiology of SVD. Intracranial arterial calcification could act as a potential marker of SVD. Introduction Atherosclerosis is a systemic vascular process that is considered a major cause of cerebrovascular and cardiovascular di...
Source: Frontiers in Neurology - April 30, 2019 Category: Neurology Source Type: research

Air pollution linked to silent strokes
Conclusion This cross-sectional study has suggested a link between exposure to small particles in the air (one form of pollution) and the presence of "silent stroke" in older adults – small areas of damage to the brain tissue that are not severe enough to cause obvious symptoms. There are a number of limitations to be aware of when assessing the results of this study: While there was an association between particulate matter in the air and total brain volume, this was no longer statistically significant after taking into account whether people have conditions such as high blood pressure, which can also affec...
Source: NHS News Feed - April 24, 2015 Category: Consumer Health News Tags: Lifestyle/exercise Neurology Source Type: news

Characterizing the Penumbras of White Matter Hyperintensities and Their Associations With Cognitive Function in Patients With Subcortical Vascular Mild Cognitive Impairment
Conclusion In this study, reduced CBF and FA and increased MD in the inner NAWM layers for both PVWMH and DWMH suggested extensive WM alterations beyond the visible WM lesions commonly observed on clinical MRI of svMCI subjects. CBF penumbras cover more extensive WM at risk than DTI penumbras, suggesting the likelihood that compromised CBF precedes white matter integrity changes, and CBF penumbras may be a potential target for the prevention of further microstructural white matter damage. The imaging parameters investigated, however, did not correlate to cognition. Author Contributions YZ, QX, and XG conceived and desig...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Incidence and Predictors of Poststroke Depression: Results from the Framingham Heart Study (P5.034)
CONCLUSIONS: Poststroke depression is common. These data suggest that patients at particularly high risk can be identified at the time of stroke and may benefit from targeted prevention strategies.Disclosure: Dr. Salinas has nothing to disclose. Dr. Beiser has nothing to disclose. Dr. Himali has nothing to disclose. Dr. Rosand has nothing to disclose. Dr. Seshadri has nothing to disclose. Dr. Dunn has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Salinas, J., Beiser, A., Himali, J., Rosand, J., Seshadri, S., Dunn, E. Tags: Neuroepidemiology: Aging, Dementia, Cognitive, and Behavioral Neurology, General Neurology, and Research Methodology and Education Source Type: research