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AI Cough-Monitoring Can Change the Way We Diagnose Disease
How many times do you cough a day? Do you cough more when you’re indoors or outside? Or more often after you eat? Or at night? Chances are, your cough memory might not be that accurate. But all of that information about your coughing patterns could be an untapped resource to better understand your health. Coughs may be benign ways to clear a little extra phlegm, or they could be early signs of more serious conditions such as asthma, GERD (gastroesophageal reflux disease), or even lung cancer. “In the era of precision health, it’s ironic that such a problematic symptom is simply unmeasured,” says Pet...
Source: TIME: Health - April 3, 2023 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized healthscienceclimate Technology Source Type: news

Lung Effects of Household Air Pollution
J Allergy Clin Immunol Pract. 2022 Sep 2:S2213-2198(22)00869-8. doi: 10.1016/j.jaip.2022.08.031. Online ahead of print.ABSTRACTBiomass fuel smoke, secondhand smoke, and oxides of nitrogen are common causes of household air pollution (HAP). Almost 2.4 billion people worldwide use solid fuels for cooking and heating, mostly in low- and middle-income countries. Wood combustion for household heating is also common in many areas of high-income countries, and minorities are particularly vulnerable. HAP in low- and middle-income countries is associated with asthma, acute respiratory tract infections in adults and children, chroni...
Source: Clinical Lung Cancer - September 5, 2022 Category: Cancer & Oncology Authors: Anna Y Qiu Shuguang Leng Meredith McCormack David B Peden Akshay Sood Source Type: research

New Analyses Suggest Favorable Results for STELARA ® (ustekinumab) When Used as a First-Line Therapy for Bio-Naïve Patients with Moderately to Severely Active Crohn’s Disease and Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 25, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from two new analyses of STELARA® (ustekinumab) for the treatment of adults with moderately to severely active Crohn’s disease (CD) and ulcerative colitis (UC).1,2 In a modelled analysisa focused on treatment sequencing using data from randomized controlled trials, network meta-analysis and literature, results showed patient time spent in clinical remission or response was highest when STELARA was used as a first-line advanced therapy for bio-naïve patients with moderately to severely acti...
Source: Johnson and Johnson - October 25, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

TB, HIV and COVID-19: Urgent Questions as Three Epidemics Collide
This article is republished from The Conversation under a Creative Commons license. Read the original article. The post TB, HIV and COVID-19: Urgent Questions as Three Epidemics Collide appeared first on Inter Press Service.
Source: IPS Inter Press Service - Health - March 25, 2020 Category: International Medicine & Public Health Authors: External Source Tags: Africa Headlines Health Source Type: news

Bronchial inflammation, respiratory symptoms and lung function in patients who finished treatment for pulmonary tuberculosis: is it the beginning of a new disease?
Conclusion: This study suggests the existence of different celullar patterns once the treatment has finished and supports the basis of a treatment hypothesis.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Palma, I., Castro Zorrilla, L., Resguardo, A., Martinez, D., Troncoso, D., Cruz, V., Vina, J., Alves, L., Natiello, M., Estevan, R., Lazari, N., Medin, M. I., Inwentarz, S., Videla, A., Palmero, D. Tags: Allergy and immunology Source Type: research

Inhaled corticosteroid-related tuberculosis in the real world among patients with asthma and COPD: A 10-year nationwide population-based study
ConclusionAn increased risk of TB development may persist for 3 years after stopping the ICS and the risk is higher in patients with COPD regardless of the type of ICS used.
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 17, 2018 Category: Allergy & Immunology Source Type: research

Allergic bronchopulmonary aspergillosis complicating Swyer-James-Macleod's syndrome: case report and review of literature.
Authors: Sehgal IS, Dhooria S, Behera D, Agarwal R Abstract Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder that results from immune responses mounted against antigens of Aspergillus fumigatus, resulting in non-specific respiratory symptoms and structural lung damage. Classically defined in individuals suffering from bronchial asthma and cystic fibrosis, ABPA has recently been described in other lung diseases including COPD, pulmonary tuberculosis, idiopathic bronchiectasis and others. Herein, we report the first case of ABPA complicating Swyer-James-Macleod's syndrome that was successfully t...
Source: European Annals of Allergy and Clinical Immunology - September 15, 2018 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Perceptions of Severe Asthma and Asthma-COPD Overlap Syndrome Among Specialists: A Questionnaire Survey.
CONCLUSIONS: Specialists had diverse perceptions and clinical practices regarding severe asthma and ACOS patients. This heterogeneity must be considered in future studies and strategy development for severe asthma and ACOS. PMID: 29676069 [PubMed]
Source: Allergy, Asthma and Immunology Research - April 22, 2018 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Effects of Orally Ingested Arsenic on Respiratory Epithelial Permeability to Bacteria and Small Molecules in Mice
Conclusions: Peroral arsenic has little effect on local airway immune responses to bacteria but compromises respiratory epithelial barrier integrity, increasing systemic translocation of inhaled pathogens and small molecules. https://doi.org/10.1289/EHP1878 Received: 09 March 2017 Revised: 14 August 2017 Accepted: 16 August 2017 Published: 28 September 2017 Address correspondence to M.B. Fessler, National Institute of Environmental Health Sciences, 111 T.W. Alexander Dr., P.O. Box 12233, Maildrop D2-01, Research Triangle Park, NC 27709 USA. Telephone: (919) 541-3701. Email: fesslerm@niehs.nih.gov *Current address: UN...
Source: EHP Research - September 28, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Allergic bronchopulmonary aspergillosis complicating Swyer-James-Macleod's syndrome: case report and review of literature.
Authors: Sehgal IS, Dhooria S, Behera D, Agarwal R Abstract Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder that results from immune responses mounted against antigens of Aspergillus fumigatus, resulting in non-specific respiratory symptoms and structural lung damage. Classically defined in individuals suffering from bronchial asthma and cystic fibrosis, ABPA has recently been described in other lung diseases including COPD, pulmonary tuberculosis, idiopathic bronchiectasis and others. Herein, we report the first case of ABPA complicating Swyer-James-Macleod's syndrome that was successfully t...
Source: European Annals of Allergy and Clinical Immunology - May 8, 2016 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

XXIV World Allergy Congress 2015
Table of Contents A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts Jae-Min Shin, Heung-Man Lee, Il-Ho Park A2 The efficacy of a 2-week course of oral steroid in the treatment of chronic spontaneous urticaria refractory to antihistamines Hyun-Sun Yoon, Gyeong Yul Park A3 The altered distribution of follicular t helper cells may predict a more pronounced clinical course of primary sjögren’s syndrome Margit Zeher A4 Betamethasone suppresses Th2 cell development induced by langerhans cell like dendr...
Source: World Allergy Organization Journal - April 18, 2016 Category: Allergy & Immunology Source Type: research

Systems Medicine for Lung Diseases: Phenotypes and Precision Medicine in Cancer, Infection, and Allergy
Lung diseases cause an enormous socioeconomic burden. Four of them are among the ten most important causes of deaths worldwide: Pneumonia has the highest death toll of all infectious diseases, lung cancer kills the most people of all malignant proliferative disorders, chronic obstructive pulmonary disease (COPD) ranks third in mortality among the chronic noncommunicable diseases, and tuberculosis is still one of the most important chronic infectious diseases. Despite all efforts, for example, by the World Health Organization and clinical and experimental researchers, these diseases are still highly prevalent and harmful. T...
Source: Springer protocols feed by Bioinformatics - December 21, 2015 Category: Bioinformatics Source Type: news

Pharmacological treatment of bacterial infections of the respiratory tract
Publication date: Available online 14 January 2015 Source:Anaesthesia & Intensive Care Medicine Author(s): Bethan L. Barker , Chris Brightling Bacterial infection of the respiratory tract is amongst the commonest presentations to primary and secondary care. In addition to supportive care the mainstay of pharmacotherapy is antibiotics. Antibiotic treatment of bacterial infections of the respiratory tract needs to consider patient factors such as age, co-morbidities, location, previous antibiotic use, microbiological results and allergy. The emergence of multi-drug-resistant bacteria, partly a consequence of inappr...
Source: Anaesthesia and intensive care medicine - January 14, 2015 Category: Anesthesiology Source Type: research

Flow cytometry applications in the study of immunological lung disorders.
Abstract The use of flow cytometry in the clinical laboratory has grown substantially in the past decade. Flow cytometric analysis provides a rapid qualitative and quantitative description of multiple characteristics of individual cells. For example, it is possible to detect the cell size and granularity, aspects of DNA and RNA content and the presence of cell surface and nuclear markers which are used to characterize the phenotype of single cells. Flow cytometry has been used for the immunophenotyping of a variety of specimens including whole blood, bone marrow, serous cavity fluids, (cerebrospinal fluid) CSF, ur...
Source: Iranian Journal of Allergy, Asthma and Immunology - December 26, 2014 Category: Allergy & Immunology Authors: Mortaz E, Gudarzi H, Tabarsi P, M Adcock I, Masjedi MR, Jamaati HR, Garssen J, Velayati AA, A Redegeld F Tags: Iran J Allergy Asthma Immunol Source Type: research

Prevalence and determinants of self-reported chronic bronchitis among women in rural Central India
Conclusions The present study provides an insight into the prevalence of chronic bronchitis among rural women exposed to several epidemiological determinants and an opportunity to address the modifiable risk factors.
Source: Medical Journal Armed Forces India - November 22, 2014 Category: Journals (General) Source Type: research