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Condition: Cerebral Palsy
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Total 550 results found since Jan 2013.
Bilateral Uterine Artery Ligation (BUAL): Placental Insufficiency Causing Fetal Growth Restriction and Cerebral Palsy
Placental insufficiency is the leading cause of intrauterine growth restriction in the western world. The fetus, when exposed to a compromised environment, is vulnerable to a number of disorders later in life, as a consequence of the reduction in oxygen and nutrition during gestation and the resulting fetal growth restriction. These conditions include neurological disabilities such as cerebral palsy (CP), intellectual disability, epilepsy, and mental health issues in childhood (Autism and ADHD) and in later life (schizophrenia). Certainly, fetal growth restriction as a result of placental insufficiency has been strongly as...
Source: Springer protocols feed by Neuroscience - September 21, 2015 Category: Neuroscience Source Type: news
Chronic Neuromotor Disability After Complex Cardiac Surgery in Early Life
This study focuses on the presence of chronic neuromotor disabilities including cerebral palsy and motor impairments after acquired brain injury in children surviving early complex cardiac surgery, providing information on the frequency, characteristics, and predictors that may assist in prevention. (Read the full article)
Source: PEDIATRICS - October 1, 2015 Category: Pediatrics Tags: Pediatrics Digest Summary Source Type: research
Early Intervention Equals Improved Outcomes: A Case Report Presenting Improved Outcomes in a Patient with in Utero Stroke
To establish efficacy of early intervention physical, occupational and speech therapies in a female born at 31 weeks with Cerebral Palsy, Feeding difficulties and developmental delay.
Source: Archives of Physical Medicine and Rehabilitation - October 1, 2015 Category: Rehabilitation Authors: Elizabeth Niesman, Rajashree Srinivasan Tags: Research poster Source Type: research
Intrathecal versus Oral Baclofen; a Matched Cohort Study of Spasticity, Pain, Sleep, Fatigue and Quality of Life
Conclusions Long-term treatment with intrathecal compared to oral baclofen is associated with reduced spasm frequency and severity as well as greater dose stability. These benefits must be weighted against the risks of internal pump and catheter placement in patients considering intrathecal baclofen therapy.
Source: PMandR - October 21, 2015 Category: Rehabilitation Source Type: research
PathMaker Neurosystems wins the fast track at FDA for MyoRegulator device
PathMaker Neurosystems said it won expedited access pathway designation from the FDA for its MyoRegulator PM-2200 system, which is designed to treat muscle spasticity.
The MyoRegulator device, based on PathMaker’s DoubleStim technology, is designed to provide simultaneous, non-invasive stimulation at spinal and peripheral locations, the Boston-based company said.
In June PathMaker inked a deal with Proven Process to develop and manufacture a device for treating patients with muscle tone disorders using trans-spinal direct current stimulation. The MyoRegulator device aims to treat muscle spasticity in patients with ...
Source: Mass Device - October 30, 2015 Category: Medical Equipment Authors: Brad Perriello Tags: Food & Drug Administration (FDA) Neuromodulation/Neurostimulation Regulatory/Compliance PathMaker Neurosystems Inc. Source Type: news
PathMaker Neurosystems Inc. Receives Expedited Access Pathway Designation From FDA For MyoRegulator
PathMaker Neurosystems'MyoRegulatorPM-2200 system has received Expedited Access Pathway (EAP) designation and priority processing status from the U.S. Food and Drug Administration (FDA). MyoRegulator is PathMaker’s first product, and is being developed for the treatment of muscle spasticity found in patients with stroke, cerebral palsy (CP), multiple sclerosis (MS), spinal cord injury (SCI), traumatic brain injury (TBI) and numerous other neurological conditions.
Source: Medical Design Online News - November 3, 2015 Category: Medical Equipment Source Type: news
Everyday movement and use of the arms: Relationship in children with hemiparesis differs from adults.
CONCLUSIONS: In children with upper-extremity hemiparesis who meet the study intake criteria amount of movement of the more-affected arm in daily life is not related to its amount to use, suggesting that children differ from adults in this respect.
PMID: 26410062 [PubMed - in process]
Source: Journal of Pediatric Rehabilitation Medicine - November 19, 2015 Category: Rehabilitation Tags: J Pediatr Rehabil Med Source Type: research
Correlates of a Single-Item Quality-of-Life Measure in People Aging with Disabilities
Objective: Practical quality-of-life (QOL) screening methods are needed to help focus clinical decision-making on what matters to individuals with disabilities.
Design: A secondary analysis of a database from a large study of adults aging with impairments focused on four diagnostic groups: cerebral palsy (n = 134), polio (n = 321), rheumatoid arthritis (n = 99), and stroke (n = 82). Approximately 20% of cases were repeated measures of the same individuals 3–5 yrs later. Functional levels, depression, and social interactions were assessed. The single-item, subjective, seven-point Kemp Quality of Life Scale measured QOL. F...
Source: American Journal of Physical Medicine and Rehabilitation - November 22, 2015 Category: Rehabilitation Tags: Original Research Articles Source Type: research
Intrathecal Versus Oral Baclofen: A Matched Cohort Study of Spasticity, Pain, Sleep, Fatigue, and Quality of Life
Conclusions Long-term treatment with intrathecal compared with oral baclofen is associated with reduced spasm frequency and severity as well as greater dose stability. These benefits must be weighed against the risks of internal pump and catheter placement in patients considering intrathecal baclofen therapy.
Source: PMandR - November 22, 2015 Category: Rehabilitation Source Type: research
Using a goal attainment scale in the evaluation of outcomes in patients with diplegic cerebral palsy
Three-dimensional gait analysis is a standard evaluation of ambulant patients with cerebral palsy (CP). However, kinematic and kinetic outcomes may overlook a patient's goals and individual needs, such as pain relief. A Goal Attainment Scale (GAS) provides subjective information about a patient's needs. Goal Attainment Scales (GASs) were initially used in the 1960s in mental health [1], but have since been applied to other aspects of health care including stroke rehabilitation and geriatric care [2,3].
Source: Gait and Posture - December 14, 2015 Category: Orthopaedics Authors: D. McMorran, L.W. Robinson, G. Henderson, J. Herman, J.E. Robb, M.S. Gaston Tags: Full length Article Source Type: research
Induction of neurorestoration from endogenous stem cells.
Abstract
Neural stem cells persist in the subventricular zone lining the ventricle of the adult brain. The resident stem/progenitor cells can be stimulated in vivo by neurotrophic factors, hematopoietic growth factors, magnetic stimulation and/or physical exercise. In both animals and humans, the differentiation and survival of neurons arising from the subventricular zone may be also regulated by the trophic factors. The presence of stem/progenitor cells in the adult brain and the fact that the production of new neurons occurs at specific sites suggest a possibility for the treatment of otherwise incurable neurolo...
Source: Cell Transplantation - January 18, 2016 Category: Cytology Authors: Yu JH, Seo JH, Lee JY, Lee MY, Cho SR Tags: Cell Transplant Source Type: research
Alana Clark with cerebral palsy becomes a bodybuilder
Alana Clark, 51, from Bristol, has beat disability and a stroke that left her unable to talk to be crowned winner but she says she only sees her late son Tom's face when she's on stage.
Source: the Mail online | Health - January 22, 2016 Category: Consumer Health News Source Type: news
A Novel Application of Eddy Current Braking for Functional Strength Training During Gait.
In this study, we created a lightweight and wearable device using eddy current braking to provide resistance to the knee. We then validated the device by having subjects wear it during a walking task through varying resistance levels. Electromyography and kinematics were collected to assess the biomechanical effects of the device on the wearer. We found that eddy current braking provided resistance levels suitable for functional strength training of leg muscles in a package that is both lightweight and wearable. Applying resistive forces at the knee joint during gait resulted in significant increases in muscle activation o...
Source: Annals of Biomedical Engineering - January 27, 2016 Category: Biomedical Engineering Authors: Washabaugh EP, Claflin ES, Gillespie RB, Krishnan C Tags: Ann Biomed Eng Source Type: research
Relationship between somatosensory deficit and brain somatosensory system after early brain lesion: A morphometric study.
Abstract
Cerebral Palsy (CP) is a group of permanent motor disorders due to non-progressive damage to the developing brain. Poor tactile discrimination is common in children with unilateral CP. Previous findings suggest the crucial role of structural integrity of the primary (S1) and secondary (S2) somatosensory areas located in the ipsilesional hemisphere for somatosensory function processing. However, no focus on the relationship between structural characteristics of ipsilesional S1 and S2 and tactile discrimination function in paretic hands has been proposed. Using structural MRI and a two-point discrimination ...
Source: European Journal of Paediatric Neurology - January 19, 2016 Category: Neurology Authors: Perivier M, Delion M, Chinier E, Loustau S, Nguyen S, Ter Minassian A, Richard I, Dinomais M Tags: Eur J Paediatr Neurol Source Type: research
Botulinum Toxin Treatment of Spasticity in Adults and Children
Semin Neurol 2016; 36: 064-072DOI: 10.1055/s-0036-1571847Spasticity is a frequent symptom in stroke, multiple sclerosis, cerebral or spinal trauma, and cerebral palsy that affects and disables a large number of adults and children. In this review, we discuss the pathophysiology and nonpharmacologic and pharmacologic treatments of spasticity with emphasis on the role of botulinum neurotoxins (BoNTs). The world literature is reviewed on double-blind and placebo-controlled clinical trials reporting safety and efficacy of BoNT treatment in adult spasticity and spasticity of children with cerebral palsy. The evidence for effica...
Source: Seminars in Neurology - February 11, 2016 Category: Neurology Authors: Moeini-Naghani, ImanHashemi-Zonouz, TaranehJabbari, Bahman Source Type: research
