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Total 84 results found since Jan 2013.

Off-Hour Admission and Mortality Risk for 28 Specific Diseases: A Systematic Review and Meta-Analysis of 251 Cohorts Epidemiology
Conclusions Off-hour admission is associated with increased mortality risk, and the associations varied substantially for different diseases. Specialists, nurses, as well as hospital administrators and health policymakers can take these findings into consideration to improve the quality and continuity of medical services.
Source: JAHA:Journal of the American Heart Association - March 17, 2016 Category: Cardiology Authors: Zhou, Y., Li, W., Herath, C., Xia, J., Hu, B., Song, F., Cao, S., Lu, Z. Tags: Epidemiology, Risk Factors, Health Services, Meta Analysis, Mortality/Survival Source Type: research

Health status of populations living in French overseas territories in 2012, compared with metropolitan France: An analysis of the national health insurance database.
CONCLUSION: This study highlights the utility of administrative database to compare and follow population health status considering healthcare use. Specific Public Health policies are justified for FOT, taking into account the specific context of each FOT, the necessity of prevention initiatives and screening to reduce the frequency of the chronic diseases. PMID: 27238162 [PubMed - as supplied by publisher]
Source: Revue d Epidemiologie et de Sante Publique - May 31, 2016 Category: Epidemiology Tags: Rev Epidemiol Sante Publique Source Type: research

Ask JJ: Type 2 Diabetes
Dear JJ: My doctor just diagnosed me with pre-diabetes. Type 2 diabetes runs in my family, but I will not accept it as my fate. You've written about sugar's detrimental impact, so how can I get this under control so it doesn't blow up into full-blown diabetes? Diabetes doesn't happen overnight or linearly, but when your metabolic machinery breaks, serious havoc ensues. The massive repercussions can become deadly. Every time you eat, you raise blood sugar, which triggers your pancreas to release a hormone called insulin. Every food raises blood sugar, but high-sugar impact foods do it big time. Your pancreas "secretes s...
Source: Healthy Living - The Huffington Post - June 16, 2016 Category: Consumer Health News Source Type: news

Excess body fat now linked to 13 different types of cancer
"Experts have linked eight more cancers to being overweight or obese, nearly tripling the list from five to 13," the Daily Mail reports. This is the latest finding of the International Agency for Research on Cancer (IARC), a group of cancer experts from around the world that look at risk factors for cancer.  What is the basis for these reports? The headlines are based on a report published in the peer-reviewed New England Journal of Medicine. The report is not exactly new research, but a review of previously published studies that looked at the link between weight and cancers. It is the result of a working g...
Source: NHS News Feed - August 25, 2016 Category: Consumer Health News Tags: Cancer Obesity Lifestyle/exercise Source Type: news

Men From The South Are More Likely To Die From Smoking-Related Cancers
Smoking causes nearly 29 percent of all cancer deaths among Americans over the age of 35, according to a new analysis published in JAMA Internal Medicine. But that doesn’t tell the full story. Men from the top five southern states skew this data, dying at a rate that’s 40 percent higher than the national average. The higher proportion of cancer deaths attributable to smoking in the South isn’t simply because people in that region smoke more ― that distinction goes to the Midwest. Instead, experts say, the lack of funding for tobacco control programs means that there are less resources for people wh...
Source: Science - The Huffington Post - November 1, 2016 Category: Science Source Type: news

Milk and dairy products: good or bad for human health? An assessment of the totality of scientific evidence.
CONCLUSION: The totality of available scientific evidence supports that intake of milk and dairy products contribute to meet nutrient recommendations, and may protect against the most prevalent chronic diseases, whereas very few adverse effects have been reported. PMID: 27882862 [PubMed - in process]
Source: Food and Nutrition Research - November 26, 2016 Category: Nutrition Authors: Thorning TK, Raben A, Tholstrup T, Soedamah-Muthu SS, Givens I, Astrup A Tags: Food Nutr Res Source Type: research

Intra-hospital correlations among 30-day mortality rates in 18 different clinical and surgical settings
Conclusions</div>The variability in 30-day mortality rates at hospital level and the correlation between risk mortality rates suggest that there may be common hospital-wide factors influencing short-term mortality.</span>
Source: International Journal for Quality in Health Care - January 31, 2017 Category: Global & Universal Source Type: research

Assessing the Safety of Sitagliptin in Older Participants in the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS)
CONCLUSIONS Among older patients with well-controlled type 2 diabetes and cardiovascular disease, sitagliptin had neutral effects on cardiovascular risk and raised no significant safety concerns.
Source: Diabetes Care - March 20, 2017 Category: Endocrinology Authors: Bethel, M. A.; Engel, S. S.; Green, J. B.; Huang, Z.; Josse, R. G.; Kaufman, K. D.; Standl, E.; Suryawanshi, S.; Van de Werf, F.; McGuire, D. K.; Peterson, E. D.; Holman, R. R.; for the TECOS Study Group Tags: Emerging Science and Concepts for Management of Diabetes and Aging Source Type: research

Two older drugs could be 'repurposed' to fight dementia
Conclusion This early stage experimental research has demonstrated a beneficial neurological effect of trazodone and dibenzoylmethane on mice with diseases mimicking neurodegenerative diseases. It is important to acknowledge that this is animal research and therefore the drugs might not have the same effect when they are trialled on humans. That being said, trazodone is already an approved drug for depression and sleep problems and has therefore already passed safety tests. If the mechanisms of neurodegeneration in humans and mice are similar, it is possible trazodone could be used in the future in treating Alzheimer's and...
Source: NHS News Feed - April 20, 2017 Category: Consumer Health News Tags: Older people Neurology Medication Source Type: news

MicroRNAs Mediated MMP Regulation: Current Diagnostic and Therapeutic Strategies for Metabolic Syndrome.
Abstract Metabolic syndrome (MS) is a global socioeconomic problem rapidly progressing in accordance with increasing body mass index (BMI) and age. It is a consortium of risk factors, such as dyslipidaemia, insulin resistance, leptin resistance, reduced adiponectin, glucose intolerance, hyperglycemia, and hypertension. Collectively, these factors accelerate the onset of type 2 diabetes mellitus, cardiovascular disease, stroke, and certain cancers such as breast, liver pancreatic, and colon cancer. Extracellular matrix (ECM) and basement membrane remodeling play a central role during pathogenesis of MS as they regu...
Source: Current Gene Therapy - July 7, 2017 Category: Genetics & Stem Cells Authors: Saxena S, Jain A, Rani V Tags: Curr Gene Ther Source Type: research

UCLA helps many to live long and prosper
In Westwood, more than 100 faculty experts from 25 departments have embarked on anall-encompassing push to cut the health and economic impacts of depression in half by the year 2050. The mammoth undertaking will rely on platforms developed by the new Institute for Precision Health, which will harness the power of big data and genomics to move toward individually tailored treatments and health-promotion strategies.On the same 419 acres of land, researchers across the spectrum, from the laboratory bench to the patient bedside, are ushering in a potentially game-changing approach to turning the body ’s immune defenses again...
Source: UCLA Newsroom: Health Sciences - November 9, 2017 Category: Universities & Medical Training Source Type: news

Multiple Thrombi in the Heart in Trousseau Syndrome Caused by Pancreatic Carcinoma
A 65-year-old woman presented to our emergency room because of sudden onset of right hemiparesis with severe fatigue. Neurological examination revealed right hemiparesis with right facial numbness and an extensor planter response on the right side.Magnetic resonance imaging with diffusion-weighted imaging revealed multiple highintensity areas in both cerebral hemispheres and the right cerebellum. A diagnosis of acute stage of multiple brain infarctions caused by emboli was made. An abdominal computed tomography showed a pancreatic tumor with multiple liver metastases.
Source: Journal of Stroke and Cerebrovascular Diseases - March 1, 2018 Category: Neurology Authors: Sho Takeshita, Toshiyasu Ogata, Hidekazu Mera, Jun Tsugawa, Mikiko Aoki, Morishige Takeshita, Yoshio Tsuboi Tags: Case Studies Source Type: research

Summary: International Kidney Cancer Symposium
Conclusions:  Ideal ischemia time is 20-25 minutes or less improves short and long term renal function. >25 minutes carried 5 year risk of new onset stage 4 CKD No differences on GFR for cold vs. warm ischemia times Preoperative GFR and the percent of kidney preserved was a better predictor of post op GFR.  No ischemia preserves renal function better than warm. Longer cold ischemia times were equivalent to shorter warm ischemia times. Quality and quantity of the remaining kidney is associated with ultimate renal function. Robotics in RCC Surgery Gennady Bratslavsky, MD The opening question ...
Source: Kidney Cancer Association - December 15, 2011 Category: Urology & Nephrology Source Type: news