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Cancer: Brain Cancers
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Total 18961 results found since Jan 2013.
Biomarkers and their combination in a prediction of decompensation after an index hospitalization for acute heart failure
CONCLUSION: BNP, cystatin C, and CA125 are predictors of decompensation, and their combined usage leads to better prediction of new decompensation.PMID:37636186 | PMC:PMC10451570 | DOI:10.4103/jfmpc.jfmpc_1456_22
Source: Primary Care - August 28, 2023 Category: Primary Care Authors: Azra Durak-Nalbantic Edin Begic Alden Begic Alen Dzubur Orhan Lepara Rusmir Baljic Aida Hamzic-Mehmedbasic Damir Rebic Enisa Hodzic Mirza Halimic Almir Badnjevic Source Type: research
Modeling Gamma Knife Radiosurgical Toxicity for Multiple Brain Metastases
CONCLUSION: Surface area was the most accurate univariate predictor of V12 for metastatic lesions. We developed a preplan model for brain metastases that can help better estimate radionecrosis risk, determine prescription doses given a target V12, and provide safe dose escalation strategies without the use of any planning software.PMID:37640162 | DOI:10.1016/j.radonc.2023.109874
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - August 28, 2023 Category: Radiology Authors: Eric J Hsu Yulong Yan Robert D Timmerman Zabi Wardak Tu D Dan Toral R Patel Dat T Vo Strahinja Stojadinovic Source Type: research
Assessment and tailored physical rehabilitation approaches in persons with cerebellar impairments targeting mobility and walking according to the International Classification of Functioning: a systematic review of case-reports and case-series
CONCLUSIONS: A comprehensive test battery to encompass the key features of a PwCI on different levels of the ICF is needed to manage heterogeneity. Measures on body function level should be included in interventions.PMID:37639546 | DOI:10.1080/09638288.2023.2248886
Source: Disability and Rehabilitation - August 28, 2023 Category: Rehabilitation Authors: Anne Bogaert Francesco Roman ò Pierre Cabaraux Peter Feys Lousin Moumdjian Source Type: research
Effects of mitragynine on viability, proliferation, and migration of C6 rat glioma, SH-SY5Y human neuroblastoma, and HT22 immortalized mouse hippocampal neuron cell lines
This study aimed to investigate the antitumor effects of MG in C6 rat glioma and SH-SY5Y human neuroblastoma tumor cell lines compared with those in the non-tumor HT22 mouse hippocampal neuronal cell line. MTT assay for cell viability, clonogenic and wound healing assays for cell migration, Hoechst 33342/propidium iodide staining for nuclear morphology, and cell cycle distribution using flow cytometry were performed. MG at 125.47 μM (50 μg/ml) significantly reduced the viability of all cell lines, and the clonogenicity of C6 glioma cells began decreasing at 75.28 μM (30 μg/ml) of MG. Cell migration was inhibited in C6 ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - August 28, 2023 Category: Drugs & Pharmacology Authors: Kittikun Viwatpinyo Sujira Mukda Sakan Warinhomhoun Source Type: research
Modeling Gamma Knife Radiosurgical Toxicity for Multiple Brain Metastases
CONCLUSION: Surface area was the most accurate univariate predictor of V12 for metastatic lesions. We developed a preplan model for brain metastases that can help better estimate radionecrosis risk, determine prescription doses given a target V12, and provide safe dose escalation strategies without the use of any planning software.PMID:37640162 | DOI:10.1016/j.radonc.2023.109874
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - August 28, 2023 Category: Radiology Authors: Eric J Hsu Yulong Yan Robert D Timmerman Zabi Wardak Tu D Dan Toral R Patel Dat T Vo Strahinja Stojadinovic Source Type: research
Spectral flow cytometry identifies distinct nonneoplastic plasma extracellular vesicle phenotype in glioblastoma patients
CONCLUSIONS: Multiparametric analysis demonstrates that GBM patients have a distinct nonneoplastic plasma EV phenotype compared to ND. This simple rapid analysis can be performed without purifying tumor EVs and may serve as the basis of a liquid biopsy.PMID:37638345 | PMC:PMC10457026 | DOI:10.1093/noajnl/vdad082
Source: Adv Data - August 28, 2023 Category: Epidemiology Authors: Abudumijiti Zack Aibaidula Cori E Fain Luz Cumba Garcia Annelise Wier Samantha M Bouchal Megan M Bauman Mi-Yeon Jung Jann N Sarkaria Aaron J Johnson Ian F Parney Source Type: research
Bevacizumab plus erlotinib versus erlotinib alone for advanced EGFR-mutant non-small cell lung cancer: a meta-analysis of randomized clinical trials
CONCLUSIONS: Combination of bevacizumab and erlotinib can prolong progression-free survival but not overall survival compared to erlotinib alone in advanced EGFR-mutant non-small cell lung cancer patients. The combination therapy not only can prolong progression-free survival but also has a tendency to prolong overall survival for patients with brain metastasis at baseline.PMID:37635242 | DOI:10.1186/s40001-023-01272-7
Source: Cell Research - August 27, 2023 Category: Cytology Authors: Ruijian Li Weiyi Li Fang Zhang Shanshan Li Source Type: research
Local Delivery of Nimustine Hydrochloride against Brain Tumors: Basic Characterization Study
Tohoku J Exp Med. 2023 Aug 25. doi: 10.1620/tjem.2023.J069. Online ahead of print.NO ABSTRACTPMID:37635063 | DOI:10.1620/tjem.2023.J069
Source: The Tohoku Journal of Experimental Medicine - August 27, 2023 Category: Research Authors: Xiaodong Shao Ryuta Saito Aya Sato Saori Okuno Daisuke Saigusa Ritsumi Saito Akira Uruno Yoshinari Osada Masayuki Kanamori Teiji Tominaga Source Type: research
A Radiomics-Based Model for Potentially More Accurate Identification of Subtypes of Breast Cancer Brain Metastases
CONCLUSION: Our radiomics-based model represents an incremental advance in the classification of BCBM subtypes, thereby facilitating a more appropriate personalized therapy.PMID:37634634 | DOI:10.3349/ymj.2023.0047
Source: Yonsei Medical Journal - August 27, 2023 Category: Universities & Medical Training Authors: Seonghyeon Cho Bio Joo Mina Park Sung Jun Ahn Sang Hyun Suh Yae Won Park Sung Soo Ahn Seung-Koo Lee Source Type: research
Synthesis and biological evaluation of simplified ajudazol derivatives reveal potent 5-lipoxygenase inhibition and considerable apoptotic activity in neuroblastoma cells
Bioorg Med Chem Lett. 2023 Aug 25:129464. doi: 10.1016/j.bmcl.2023.129464. Online ahead of print.ABSTRACTSimplified analogues of the myxobacterial polyketide ajudazol were obtained by synthesis and evaluated for their biological activities. Potent simplified 5-lipoxygenase inhibitors were identified. Moreover, strong antiproliferative and apoptotic activities were observed in brain cancer cell lines at low nano- to micromolar concentrations.PMID:37634760 | DOI:10.1016/j.bmcl.2023.129464
Source: Bioorganic and Medicinal Chemistry Letters - August 27, 2023 Category: Chemistry Authors: Philipp Wollnitzke Raphael Wagner Sumaiya Yasmeen Afsar Markus Werner Robin Geschold Christa E M üller Oliver Werz Gerhild van Echten-Deckert Dirk Menche Source Type: research
Real-life evidence about the use of intravenous brivaracetam in urgent seizures: The BRIV-IV study
CONCLUSION: IV-BRV in emergency settings was effective, and tolerability was good for most patients. However, a larger series is needed to confirm the outcomes.PMID:37634373 | DOI:10.1016/j.yebeh.2023.109384
Source: Epilepsy and Behaviour - August 27, 2023 Category: Neurology Authors: Vicente Villanueva Xiana Rodriguez-Osorio Álvaro Juiz-Fernández Debora Sayas Kevin Hampel Ascensi ón Castillo Javier Montoya Mercedes Garc és Dulce Campos Eduardo Rubio-Naz ábal Alejandro Fern ández-Cabrera Ariadna Gifreu Estevo Santamarina Guillerm Source Type: research
Repetitive and compulsive behavior after Early-Life-Pain associated with reduced long-chain sphingolipid species
CONCLUSION: The results suggest that ELP may predispose to chronic "pain" and compulsive psychopathology in part mediated by alterations of sphingolipid metabolism, which have been previously described in the context of addiction and psychiatric diseases.PMID:37635256 | DOI:10.1186/s13578-023-01106-3
Source: Cancer Control - August 27, 2023 Category: Cancer & Oncology Authors: Alexandra Vogel Timo Ueberbach Annett Wilken-Schmitz Lisa Hahnefeld Luisa Franck Marc-Philipp Weyer Tassilo Jungenitz Tobias Schmid Giulia Buchmann Florian Freudenberg Ralf P Brandes Robert Gurke Stephan W Schwarzacher Gerd Geisslinger Thomas Mittmann Irm Source Type: research
