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Specialty: Neurology
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Total 226 results found since Jan 2013.
Neurologic Outcome Predictors in Pediatric Intracerebral Hemorrhage Brief Report
Background and Purpose—Intracerebral hemorrhage is a considerable source of morbidity and mortality. This 3-center study describes outcomes of pediatric intracerebral hemorrhage and identifies 2-year neurological outcome predictors.Methods—Children 29 days to 18 years of age presenting with intracerebral hemorrhage from March 2007 to May 2015 were enrolled prospectively. Exclusion criteria included trauma; intracranial tumor; hemorrhagic transformation of arterial ischemic stroke or cerebral sinovenous thrombosis; isolated subdural, epidural, or subarachnoid hemorrhage; and abnormal baseline neurological function. Intr...
Source: Stroke - June 25, 2018 Category: Neurology Authors: Giulia S. Porcari, Lauren A. Beslow, Rebecca N. Ichord, Daniel J. Licht, Jonathan T. Kleinman, Lori C. Jordan Tags: Pediatrics, Prognosis, Mortality/Survival, Intracranial Hemorrhage Brief Reports Source Type: research
Isosteviol sodium injection improves outcomes by modulating TLRs/NF-κB-dependent inflammatory responses following experimental traumatic brain injury in rats
Previous studies have shown that isosteviol sodium (STVNa) protects against permanent cerebral ischemia injury by inhibition of the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB)-mediated inflammatory responses. Overwhelming evidence shows that toll-like receptors (TLRs) are the upstream regulators of NF-κB. On the basis of the similarity of the pathology caused by traumatic brain injury (TBI) and stroke, we speculated that STVNa may have a therapeutic effect against TBI through regulation of the TLRs/NF-κB signaling-mediated inflammatory response. Thus, we studied the potential therapeutic effec...
Source: NeuroReport - June 7, 2018 Category: Neurology Tags: Cellular, Molecular and Developmental Neuroscience Source Type: research
Association of Cancer Cell Type and Extracellular Vesicles With Coagulopathy in Patients With Lung Cancer and Stroke Brief Report
Conclusions—Our findings indicate that cancer cell type is associated with circulating EV levels and coagulopathy in patients with lung cancer and stroke.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Jong-Won Chung, Yeon Hee Cho, Myung-Ju Ahn, Mi Ji Lee, Gyeong-Moon Kim, Chin-Sang Chung, Oh Young Bang Tags: Biomarkers, Mechanisms, Translational Studies, Cerebrovascular Disease/Stroke, Thrombosis Brief Reports Source Type: research
Lacunar Stroke, Cavernous Angioma, and Fusiform Aneurysm Due to Irradiation for Pilocytic Astrocytoma —A Case Report
We describe a rare case of a pediatric patient who presented multiple different types of vascular events consecutively in the irradiated field including lacunar stroke because of occlusion of perforating artery, intraventricular hemorrhage from cavernoma, and subarachnoid hemorrhage because of the rupture of fusiform aneurysm, 6 years after radiotherapy against pilocytic astrocytoma.
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2018 Category: Neurology Authors: Maruyama Kunitaka, Takuya Akai, Naoki Akioka, Takahiro Tomita, Shoichi Nagai, Satoshi Kuroda Tags: Case Studies Source Type: research
Multiple Thrombi in the Heart in Trousseau Syndrome Caused by Pancreatic Carcinoma
A 65-year-old woman presented to our emergency room because of sudden onset of right hemiparesis with severe fatigue. Neurological examination revealed right hemiparesis with right facial numbness and an extensor planter response on the right side.Magnetic resonance imaging with diffusion-weighted imaging revealed multiple highintensity areas in both cerebral hemispheres and the right cerebellum. A diagnosis of acute stage of multiple brain infarctions caused by emboli was made. An abdominal computed tomography showed a pancreatic tumor with multiple liver metastases.
Source: Journal of Stroke and Cerebrovascular Diseases - March 1, 2018 Category: Neurology Authors: Sho Takeshita, Toshiyasu Ogata, Hidekazu Mera, Jun Tsugawa, Mikiko Aoki, Morishige Takeshita, Yoshio Tsuboi Tags: Case Studies Source Type: research
Calcified Cerebral Embolism Due to a Calcified Amorphous Tumor
A 59-year-old man developed brain embolism in the frontal and parietal cortex. Brain CT showed a high-density spot in the upper branch of the left middle cerebral artery, indicating calcified cerebral embolism. Calcified amorphous tumor attached to the mitral valve was identified as the cause of embolism. After surgical resection, anticoagulation was started and recurrent stroke did not occur.
Source: Journal of Stroke and Cerebrovascular Diseases - February 22, 2018 Category: Neurology Authors: Yoichiro Nagao, Makoto Nakajima, Tomoo Hirahara, Kuniyasu Wada, Tadashi Terasaki, Michiko Nagamine, Yukio Ando Tags: Case Studies Source Type: research
Emergency electroencephalogram: Usefulness in the diagnosis of nonconvulsive status epilepticus by the on-call neurologist
Conclusions Our experience finds that, in an appropriate clinical context, EmEEG performed by the on-call neurologist is a sensitive and specific tool for diagnosing NCSE.
Source: Neurologia - January 9, 2018 Category: Neurology Source Type: research
Neural correlates of improvements in personality and behavior following a neurological event
Publication date: Available online 21 November 2017 Source:Neuropsychologia Author(s): Marcie L. King, Kenneth Manzel, Joel Bruss, Daniel Tranel Research on changes in personality and behavior following brain damage has focused largely on negative outcomes, such as increased irritability, moodiness, and social inappropriateness. However, clinical observations suggest that some patients may actually show positive personality and behavioral changes following a neurological event. In the current work, we investigated neuroanatomical correlates of positive personality and behavioral changes following a discrete neurological e...
Source: Neuropsychologia - November 23, 2017 Category: Neurology Source Type: research
The phosphodiesterase-4 inhibitor, FCPR16, attenuates ischemia-reperfusion injury in rats subjected to middle cerebral artery occlusion and reperfusion.
This study indicates that FCPR16 has protective effects against cerebral ischemia-reperfusion injury through inhibiting inflammation and apoptosis via the cAMP/CREB pathway, while it has low emetogenic potential.
PMID: 29155261 [PubMed - as supplied by publisher]
Source: Brain Research Bulletin - November 16, 2017 Category: Neurology Authors: Chen J, Yu H, Zhong J, Feng H, Wang H, Cheng Y, Zou Z, Huang C, Zhou Z, Zheng W, Xu J Tags: Brain Res Bull Source Type: research
Headache and pregnancy: a systematic review
AbstractThis systematic review summarizes the existing data on headache and pregnancy with a scope on clinical headache phenotypes, treatment of headaches in pregnancy and effects of headache medications on the child during pregnancy and breastfeeding, headache related complications, and diagnostics of headache in pregnancy. Headache during pregnancy can be both primary and secondary, and in the last case can be a symptom of a life-threatening condition. The most common secondary headaches are stroke, cerebral venous thrombosis, subarachnoid hemorrhage, pituitary tumor, choriocarcinoma, eclampsia, preeclampsia, idiopathic ...
Source: The Journal of Headache and Pain - October 19, 2017 Category: Neurology Source Type: research
Global, regional, and national burden of neurological disorders during 1990 –2015: a systematic analysis for the Global Burden of Disease Study 2015
Publication date: Available online 17 September 2017 Source:The Lancet Neurology Author(s): GBD 2015 Neurological Disorders Collaborator GroupValery LFeiginAmanuel AlemuAbajobirKalkidan HassenAbateFoadAbd-AllahAbdishakur MAbdulleSemaw FeredeAberaGebre YitayihAbyuMuktar BeshirAhmedAmani NidhalAichourIbtihelAichourMiloud Taki EddineAichourRufus OlusolaAkinyemiSamerAlabedRajaaAl-RaddadiNelsonAlvis-GuzmanAzmeraw T.AmareHosseinAnsariPalwashaAnwariJohanÄrnlövHamidAsayeshSolomon WeldegebrealAsgedomTesfay MehariAteyLeticiaAvila-BurgosEuripideFrinelG. ArthurAvokpahoAleksandraBaracMiguelBarbozaSuzanne LBarker-ColloTillBärnighaus...
Source: The Lancet Neurology - September 19, 2017 Category: Neurology Source Type: research
Proinflammatory cytokines correlate with early exercise attenuating anxiety ‐like behavior after cerebral ischemia
ConclusionOur results indicated that early treadmill exercise attenuated anxiety‐like behavior by decreasing inflammation response, exercise conferred a great benefit of attenuating anxiety‐like behavior via anti‐inflammatory treatment may prove to be a novel neuroprotective strategy for stroke.
The manuscript provided novel evidence that early exercise‐associated decrease in neuroinflammation accompanied by a reduction in anxiety‐like behavior and cognitive impairment after the stroke. Based on these findings, we proposed that early exercise attenuated inflammation directly contributing to improve neuroprogress...
Source: Brain and Behavior - September 1, 2017 Category: Neurology Authors: Qi Zhang, Jingjun Zhang, Yuzhong Yan, Pengyue Zhang, Wei Zhang, Rong Xia Tags: ORIGINAL RESEARCH Source Type: research
