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Total 1194 results found since Jan 2013.

The accuracy of prehospital diagnosis of acute cerebrovascular accidents: an observational study.
CONCLUSIONS: Emergency physicians appear to be sensitive in diagnosing CVAs but their overall accuracy does not seem high. They tend to overuse the diagnosis of TIA. Constant education and adoption of stroke screening scales may be beneficial for emergency care systems based both on physicians and on paramedics. PMID: 26170845 [PubMed]
Source: Archives of Medical Science - July 16, 2015 Category: Biomedical Science Tags: Arch Med Sci Source Type: research

Can Oxygen Therapy Bring Dead Brain Cells Back To Life?
During my Palm Beach Anti-Aging Summit in October, I’m hosting some of the world’s leading authorities on oxygen therapy. The Summit coincides with the grand opening of my 17,000-sq.-ft. Sears Institute for Anti-Aging Medicine, where I’m unveiling a specially-designed room that houses my first hyperbaric oxygen chamber. I hope you’ll be there, as you’ll discover the newest applications and breakthroughs in this growing field. You see, when oxygen is pressurized — like it is when you’re inside the chamber — you can treat more than just chronic disease. Truth is, hyperbaric oxygen can...
Source: Al Sears, MD Natural Remedies - September 14, 2015 Category: Complementary Medicine Authors: Dr. Al Sears Tags: Brain Health brain cells hyperbaric oxygen chamber natural treatment omega-3 fatty acids Palm Beach Anti-Aging Summit Source Type: news

Can You Think Yourself Into A Different Person?
For years she had tried to be the perfect wife and mother but now, divorced, with two sons, having gone through another break-up and in despair about her future, she felt as if she’d failed at it all, and she was tired of it. On 6 June 2007 Debbie Hampton, of Greensboro, North Carolina, took an overdose of more than 90 pills – a combination of ten different prescription drugs, some of which she’d stolen from a neighbor’s bedside cabinet. That afternoon, she’d written a note on her computer: “I’ve screwed up this life so bad that there is no place here for me and nothing I can contr...
Source: Science - The Huffington Post - November 19, 2015 Category: Science Source Type: news

Cerebral ischemic events in patients with pancreatic cancer: A retrospective cohort study of 17 patients and a literature review
Abstract: Stroke is a dramatic complication of pancreatic cancer with mechanisms related to oncological disease. A better description of the characteristics of cerebrovascular events would help better understand the pathogeny and protect vulnerable patients. We thus conducted a descriptive analysis of clinical, biological, and radiological features of patients from our centers and literature. We reviewed consecutive cases of patients who presented cerebrovascular events and pancreatic cancer in 4 stroke units in Lorrain (France) between January 1, 2009 and March 31, 2015, and all reported cases of literature. We identifie...
Source: Medicine - June 1, 2016 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

A pattern of brain activity may link stress to heart attacks
Conclusion This intriguing study sets out a possible pathway by which the effects of stress on the brain could translate into inflammation in the blood vessels, and so raise the risks of cardiovascular disease. This would help to explain why people living in stressful situations, or with illnesses such as depression and anxiety, are more at risk of heart attacks and strokes. However, there are important limitations to the study which mean we should treat the findings with caution. The main study of 293 people was relatively small for a long-term study looking at cardiovascular disease, and only 22 people had a cardiovascul...
Source: NHS News Feed - January 12, 2017 Category: Consumer Health News Tags: Neurology Mental health Source Type: news

Down-regulation of NOX4 by betulinic acid protects against cerebral ischemia-reperfusion in mice
SummaryIschemic stroke leads to high potentiality of mortality and disability. The current treatment for ischemic stroke is mainly focused on intravenous thrombolytic therapy. However, ischemia/ reperfusion induces neuronal damage, which significantly influences the outcome of patients with ischemic stroke, and the exact mechanism implicated in ischemia/reperfusion injury remains unclear, although evidence shows that oxidative stress is likely to be involved. Betulinic acid is mainly known for its anti-tumor and anti-inflammatory activities. Our previous study showed that betulinic acid could decrease the reactive oxygen s...
Source: Journal of Huazhong University of Science and Technology -- Medical Sciences -- - October 1, 2017 Category: Research Source Type: research

Evaluation of the Head Multislice Computed Tomography Scan in Emergency Department.
Authors: Zadravec D, Gregurić T, Smoljan M, Mustapić M, Miličić G, Jović A, Rubil D, Tomasović D, Bašić Kes V Abstract The aim of the study was to examine the prevalence of head injuries, acute stroke and brain tumors obtained from computed tomography (CT) scans in the emergency department (ED) during a one-year period. We also assessed the potential effect of seasons on the occurrence of stroke, head trauma and tumors found on CT scans, expressed in monthly intervals. This retrospective review included all patients that underwent emergency head CT from the hospital database. A total of 3888 head CT examina...
Source: Acta Clinica Croatica - March 1, 2018 Category: General Medicine Tags: Acta Clin Croat Source Type: research

An Egg A Day Might Reduce Your Risk Of Heart Disease, Study Says
In this study however, they didn’t assess the risk of developing diabetes, which may be because diabetes is a newer disease in the Chinese population and there is not good documentation of who has it,” Richard said. Still, she noted, “this will be very important data for helping develop dietary prevention guidelines in China.” Cardiovascular disease, which takes the lives of 17.7 million people every year, is the leading cause of death and disability worldwide, according to the World Health Organization. Cardiovascular disease causes nearly a third — 31% — of all global deaths each year....
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - May 22, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Eggs Heart Disease Local TV Source Type: news

HDAC9 promotes brain ischemic injury by provoking I κBα/NF-κB and MAPKs signaling pathways.
HDAC9 promotes brain ischemic injury by provoking IκBα/NF-κB and MAPKs signaling pathways. Biochem Biophys Res Commun. 2018 Jul 18;: Authors: Lu S, Li H, Li K, Fan XD Abstract Ischemic stroke is an acute cerebrovascular disease due to poor blood flow to the brain. Nevertheless, there is still no effective therapy for it and the pathology contributing to ischemic stroke is not fully understood. Histone Deacetylase 9 (HDAC9) is a class IIa chromatin-modifying enzyme. HDAC9 gene region is a leading risk locus for large artery atherosclerotic stroke. However, the mechanisms linking HDAC9 to ischemic re...
Source: Biochemical and Biophysical Research communications - July 18, 2018 Category: Biochemistry Authors: Lu S, Li H, Li K, Fan XD Tags: Biochem Biophys Res Commun Source Type: research

Occlusive radiation cerebral vasculopathy implies medical complexity: a case report
ConclusionLate-onset occlusive radiation vasculopathy is a potentially severe iatrogenic manifestation of radiotherapy that requires a high index of suspicion as an etiology of stroke in young population, especially those with coexistent meningioma that might be a strong indicator for occlusive radiation vasculopathy as the stroke culprit. We reviewed the available literature to better understand the pathogenesis, clinical presentation, and treatment options of occlusive radiation vasculopathy. Applying perfusion studies with acetazolamide measures the cerebrovascular reserve in patients with occlusive radiation vasculopat...
Source: Journal of Medical Case Reports - June 2, 2019 Category: General Medicine Source Type: research

Janssen to Present the Strength and Promise of its Hematologic Malignancies Portfolio and Pipeline at ASH 2021
RARITAN, N.J., November 4, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that more than 45 company-sponsored abstracts, including 11 oral presentations, plus more than 35 investigator-initiated studies will be featured at the American Society of Hematology (ASH) Annual Meeting and Exposition. ASH is taking place at the Georgia World Congress Center in Atlanta and virtually from December 11-14, 2021.“We are committed to advancing the science and treatment of hematologic malignancies and look forward to presenting the latest research from our robust portfolio and pipeline during ASH...
Source: Johnson and Johnson - November 5, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Timely and Appropriate Administration of Inhaled Argon Provides Better Outcomes for tMCAO Mice: A Controlled, Randomized, and Double-Blind Animal Study
ConclusionsTimely iAr administration during ischemia showed optimal neurological outcomes and minimal infarct volumes. Moreover, an appropriate duration of argon administration was important for better neuroprotective efficacy. These findings may provide vital guidance for using argon as a neuroprotective agent and moving to clinical trials in acute ischemic stroke.
Source: Neurocritical Care - February 8, 2022 Category: Neurology Source Type: research

Activation of Wnt/Beta-Catenin Signaling Pathway as a Promising Therapeutic Candidate for Cerebral Ischemia/Reperfusion Injury
Stroke is one of the leading causes of mortality, and survivors experience serious neurological and motor behavioral deficiencies. Following a cerebral ischemic event, substantial alterations in both cellular and molecular activities occur because of ischemia/reperfusion injury. Wnt signaling is an evolutionarily conserved signaling pathway that has been manifested to play a key role in embryo development and function maintenance in adults. Overactivation of Wnt signaling has previously been investigated in cancer-based research studies. Recently, abnormal Wnt signaling activity has been observed in ischemic stroke, which ...
Source: Frontiers in Pharmacology - May 20, 2022 Category: Drugs & Pharmacology Source Type: research

UCLA study shows promise, offers hope for brain hemorrhage patients
A new endoscopic surgical procedure has been shown to be safer and to result in better outcomes than the current standard medical treatment for patients who suffer strokes as a result of brain hemorrhages, UCLA neurosurgeons have announced.   The findings from their potentially groundbreaking, randomized, controlled phase 2 clinical trial, which was conducted at multiple medical centers, were presented last week at the International Stroke Conference in Honolulu.   "These exciting results offer a glimmer of hope for a condition that most doctors have traditionally considered hopeless," said principal investigator...
Source: UCLA Newsroom: Health Sciences - February 11, 2013 Category: Universities & Medical Training Source Type: news