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Total 62 results found since Jan 2013.

Ability to Suppress TGF- β-Activated Myofibroblast Differentiation Distinguishes the Anti-pulmonary Fibrosis Efficacy of Two Danshen-Containing Chinese Herbal Medicine Prescriptions
Conclusion: This study suggests that a clinically efficacious cardiovascular Chinese herbal medicine (DLP) can be successfully repurposed to treat a lung disease in pulmonary fibrosis guided by TCM theory. Our comparative study between DLP and DHP demonstrated a critical requirement of suppressing both pro-inflammatory and pro-fibrotic pathways for the treatment of pulmonary fibrosis, supporting that a multi-component prescription capable of “removing both phlegm and blood stasis” will better achieve co-protection of heart and lung in PHD. Introduction Idiopathic pulmonary fibrosis (IPF) is a chronic ...
Source: Frontiers in Pharmacology - April 23, 2019 Category: Drugs & Pharmacology Source Type: research

Marijuana Use for Women: To Prescribe or Not to Prescribe.
Conclusions: Benefits and risks for both the patient and the offspring especially in the long term regarding marijuana use should be carefully weighed for each specific case. Standardized dosing and duration of treatment need to be determined. Recommendations should be made by physicians with expert training and after careful patient evaluation for fully informed patients, whose preference should be respected. Legislations should encourage more active basic, translational, and clinical studies. PMID: 32627638 [PubMed - as supplied by publisher]
Source: Substance Use and Misuse - July 8, 2020 Category: Addiction Tags: Subst Use Misuse Source Type: research

Telepsychotherapy with children and families: Lessons gleaned from two decades of translational research.
We describe adaptation for international contexts and strategies for troubleshooting technological challenges and working with families of varying socioeconomic strata. The extensive research literature reviewed and synthesized provides considerable support for the utility of telepsychotherapy with children with neurological conditions and their families and underscores its high level of acceptability with both diverse clinical populations and providers. During this period of heightened vulnerability and stress and reduced access to usual supports and services, telepsychotherapy approaches such as online family problem-sol...
Source: Journal of Psychotherapy Integration - June 8, 2020 Category: Psychiatry & Psychology Source Type: research

Ipsilesional spatial bias after a focal cerebral infarction in the medial agranular cortex: A mouse model of unilateral spatial neglect.
In this study, a mouse model of unilateral spatial neglect was created to investigate whether the size of the lesion is related to the severity of ipsilesional spatial bias and the recovery process. Focal infarction was induced in the right medial agranular cortex (AGm) of mice via photothrombosis. After induction of cerebral infarction, ipsilesional spatial bias was evaluated for 9 consecutive days. The major findings were as follows: (1) unilateral local infarction of the AGm resulted in ipsilateral bias during internally guided decision-making; (2) the lesion size was correlated with the degree of impairment rather than...
Source: Behavioural Brain Research - December 29, 2020 Category: Neurology Authors: Ishii D, Osaki H, Yozu A, Ishibashi K, Kawamura K, Yamamoto S, Miyata M, Kohno Y Tags: Behav Brain Res Source Type: research

4 Ways Exercise Helps Fight Aging
Everyone knows that exercise is good for you. But it’s not just beneficial for the young, healthy and already fit. It’s also one of the best defenses against the toughest aspects of aging. Exercise not only improves heart and lung health, but research shows that even modest physical activity is good for the brain, bones, muscles and mood. Numerous studies have found that lifelong exercise may keep people healthier for longer; delay the onset of 40 chronic conditions or diseases; stave off cognitive decline; reduce the risk of falls; alleviate depression, stress and anxiety; and may even help people live longer....
Source: TIME: Health - June 1, 2021 Category: Consumer Health News Authors: Liz Seegert Tags: Uncategorized Source Type: news

IJERPH, Vol. 18, Pages 10534: Knowledge and Perception of Registered Nurses Regarding the Scope of Practice of Speech-Language Pathologists
Conclusions: It is vital for nurses to understand the value, role, and scope of practice of the SLP. Further educational nursing interventions and training are necessary for effective interprofessional collaboration and teamwork.
Source: International Journal of Environmental Research and Public Health - October 8, 2021 Category: Environmental Health Authors: Sami Alhamidi Majid Alshahwan Regie Tumala Tags: Article Source Type: research

New Analyses Suggest Favorable Results for STELARA ® (ustekinumab) When Used as a First-Line Therapy for Bio-Naïve Patients with Moderately to Severely Active Crohn’s Disease and Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 25, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from two new analyses of STELARA® (ustekinumab) for the treatment of adults with moderately to severely active Crohn’s disease (CD) and ulcerative colitis (UC).1,2 In a modelled analysisa focused on treatment sequencing using data from randomized controlled trials, network meta-analysis and literature, results showed patient time spent in clinical remission or response was highest when STELARA was used as a first-line advanced therapy for bio-naïve patients with moderately to severely acti...
Source: Johnson and Johnson - October 25, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Clinical and training practices: A survey of pediatric neuropsychologists serving inpatient rehabilitation
Child Neuropsychol. 2021 Nov 1:1-25. doi: 10.1080/09297049.2021.1993809. Online ahead of print.ABSTRACTNeuropsychologists in inpatient pediatric rehabilitation settings collaborate with an interdisciplinary team to educate, evaluate, and provide intervention to patients with acquired brain injury and their families, but there are no known studies that describe or define these clinical services. Thirty-one neuropsychologists in pediatric inpatient rehabilitation settings completed an online survey. Neuropsychologists (68.2% female; 86.4% with PhD versus PsyD) from the U.S. and Canada, who represented 22 pediatric inpatient ...
Source: Child Neuropsychology - November 2, 2021 Category: Child Development Authors: Katherine T Baum Julia Smith-Paine Sarah J Tlustos Abigail Johnson Christine Petranovich Source Type: research

Tube feeding in patients with dementia is associated with a longer palliative care unit stay
CONCLUSION: The present study showed that, in patients with an established diagnosis of dementia, TF is common and independently associated with a longer length of PCU stay. Nevertheless, the study was underpowered and the results deserve confirmation in larger studies.PMID:34971282 | DOI:10.1002/alz.052919
Source: The Journal of Alzheimers Association - December 31, 2021 Category: Psychiatry Authors: Hilal Zengin Ilker Tasci Source Type: research

A novel nomogram to predict overall survival in head and neck cancer survivors with radiation-induced brain necrosis
CONCLUSION: In this LASSO-Cox model-based nomogram study, we developed and validated an easily applied model to predict overall survival in head and neck cancer survivors following an RN diagnosis.PMID:35121029 | DOI:10.1016/j.radonc.2022.01.033
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - February 5, 2022 Category: Radiology Authors: Dong Pan Xiaoming Rong Yingying Zhu Wai Tong Ng Dongping Chen Honghong Li Yongteng Xu Yamei Tang Radiation Oncology Palliative Care Collaborative Group Source Type: research

Effect of gait distance during robot training on walking independence after acute brain injury
This study aimed to determine whether the distance of gait training using a hybrid assistive limb (HAL) is related to the improvement of walking independence in patients with acute brain injury. This was an exploratory, observational study. Thirty patients having hemiplegia (functional ambulation category, FAC score ≤ 2) with acute stroke or after brain tumor surgery were included. Patients performed 4 sessions of gait training using HAL (60 min/session), 1-3 sessions/week, combined with conventional physical therapy. The gait distance achieved in the four training sessions using HAL was measured. FAC score was measured ...
Source: Assistive Technology - November 28, 2022 Category: Rehabilitation Authors: Gakuto Kitamura Manabu Nankaku Takayuki Kikuchi Hidehisa Nishi Hiroki Tanaka Toru Nishikawa Honami Yonezawa Taishi Kajimoto Takumi Kawano Ayumi Ohtagaki Eriko Mashimoto Susumu Miyamoto Ryosuke Ikeguchi Shuichi Matsuda Source Type: research