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Cancer: Squamous Cell Carcinoma
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Total 19037 results found since Jan 2013.
Influence of interleukins on prognosis of patients with oral squamous cells carcinoma
ABSTRACT Squamous cell carcinoma is a malignant neoplasm that affects the structures and tissues of the oral cavity. Interleukins (IL) synthesized from a tumor modulate a cascade reaction that may influence the prognosis of the disease. We aim to investigate in the literature whether interleukins are mediators that negatively or positively influence the prognosis of patients with oral squamous cell carcinoma. A systematic review study was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA) instructions. PubMed (including MedLine), Scopus, Web of Science, SciELO and Latin A...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - November 11, 2019 Category: Pathology Source Type: research
Oral Contraceptives Use and Risk of Cervical Cancer – A Systematic Review & Meta-Analysis
ConclusionOC pills use had a definite associated risk for developing cervical cancer specially for Adenocarcinoma and longer duration of OC pills use.
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - February 22, 2020 Category: OBGYN Source Type: research
Management of squamous cell carcinomas of the skull-base
ConclusionSquamous cell carcinoma (SCC) is the most common cancer occurring in the Head and Neck. Squamous cell carcinoma is also the most common cancer arising within the nose and sinuses of which skull-base squamous cell carcinoma is a rare subgroup.Evidence relating to the management and survival of skull-base SCC is based on expert opinion and. retrospective analyses Clinical examination and biopsy, imaging and a broad multidisciplinary team are key to the management of skull-base SCC. The information gathered should be used to guide informed discussion by suitably trained experts with patients regarding surgical appro...
Source: Journal of Neuro-Oncology - June 4, 2020 Category: Cancer & Oncology Source Type: research
Advances in pharmacotherapy for head and neck cancer
Expert Opin Pharmacother. 2021 Jun 30:1-12. doi: 10.1080/14656566.2021.1948011. Online ahead of print.ABSTRACTIntroduction: Head and neck squamous cell carcinoma (HNSCC) is one of the most common cancers worldwide and is a leading cause for cancer-related mortality. This review attempts to give a comprehensive summary of the recent developments in pharmacotherapeutic options for locally advanced/metastatic HNSCC.Areas covered: In this review, the authors conducted a systematic literature search for published articles on HNSCC in the PubMed database using the keywords 'head and neck squamous cell carcinoma or HNSCC,' 'targe...
Source: Expert Opinion on Pharmacotherapy - June 30, 2021 Category: Drugs & Pharmacology Authors: Shikhar Kumar Vanita Noronha Vijay Patil Amit Joshi Nandini Menon Kumar Prabhash Source Type: research
Squamous Cell Carcinoma Arising from Perianal Buschke-Lowenstein Tumor (Giant Condyloma Acuminatum): Comprehensive Literature Review
ConclusionGiant condyloma acuminatum is a rare variant of anogenital warts. It is known that this tumor, which is mostly thought to be benign, has a high potential for local recurrence and transformation into invasive cancer. Therefore, it is vital that the tumor is resected with clean surgical margins, even if it looks benign, and that aggressive treatment options are not avoided when necessary.
Source: Journal of Gastrointestinal Cancer - October 25, 2021 Category: Cancer & Oncology Source Type: research
Identification of a Gene Prognostic Signature for Oral Squamous Cell Carcinoma by RNA Sequencing and Bioinformatics
CONCLUSIONS: We successfully constructed a prognostic signature to predict prognosis and identified five candidate genes associated with the OS of OSCC patients that are potential tumor biomarkers and targets in OSCC.PMID:33869632 | PMC:PMC8032525 | DOI:10.1155/2021/6657767
Source: Biomed Res - April 19, 2021 Category: Research Authors: Yang-Yang Zhang Ming-Hui Mao Zheng-Xue Han Source Type: research
Prognostic value of programmed cell death ligand-1 expression in the tumor-infiltrating immune cells of patients with lung cancer: A meta-analysis
Mol Clin Oncol. 2021 Aug;15(2):167. doi: 10.3892/mco.2021.2329. Epub 2021 Jun 18.ABSTRACTSeveral studies have investigated the prognostic significance of programmed cell death ligand 1 (PD-L1)-positive expression in the tumor cells (TC) of patients with lung cancer. However, tumor-infiltrating immune cell (TIIC)-based PD-L1 expression and its prognostic value remain controversial. The present meta-analysis was performed on 11 studies comprising 2,685 patients, which were identified by a systematic search on the PubMed, PMC, Web of Science and Embase databases. The databases were searched for published articles up to Octobe...
Source: Clinical Lung Cancer - July 1, 2021 Category: Cancer & Oncology Authors: Birhanu Aberha Berele Guifang Yang Ti Wu Source Type: research
The Notch1 gene may control cell chemoresistance in esophageal squamous cell cancer
CONCLUSIONS: Notch1 gene missense mutation leads to an increase in the number of water-bridge bonds, thus enhancing the Notch1-DLL4 interaction, which may lead to tighter Notch1-DLL4 binding, either making the pathway easier to activate or increasing the length of time it is active.PMID:35116634 | PMC:PMC8799163 | DOI:10.21037/tcr-21-447
Source: Cancer Control - February 4, 2022 Category: Cancer & Oncology Authors: Kun Gao Wenqun Xing Xianben Liu Jizhao Liu Haibo Sun Wentao Hao Yan Zheng Source Type: research
Predictive Role of Tumor-Stroma Ratio for Survival of Patients With Non-Small Cell Lung Cancer: A Meta-Analysis
Conclusion: Tumor TSR could be used as a predictor of survival in patients with NSCLC. The relative proportion of patients with SCC/AC in the included NSCLC patients may be an important determinant for the association between TSR and survival in NSCLC. Stroma richness may be a predictor of poor survival in patients with lung SCC, but a predictor of better survival in patients with lung AC.PMID:35132307 | PMC:PMC8817052 | DOI:10.3389/pore.2021.1610021
Source: Cell Research - February 8, 2022 Category: Cytology Authors: Xuefeng Zhang Hongfu Ma Liang Zhang Fenghuan Li Source Type: research
Prevalence of Merkel Cell Polyomavirus in Normal and Lesional Skin: A Systematic Review and Meta-Analysis
Front Oncol. 2022 Mar 22;12:868781. doi: 10.3389/fonc.2022.868781. eCollection 2022.ABSTRACTThe prevalence of Merkel cell polyomavirus(MCPyV) in Merkel cell carcinoma(MCC) and non-MCC skin lesions and its possible role in the etiology of other skin diseases remain controversial. To systematically assess the association between MCPyV infection and MCC, non-MCC skin lesions, and normal skin. For this systematic review and meta-analysis, a comprehensive search for eligible studies was conducted using Medline Ovid, Pubmed, Web of Science, and the Cochrane CENTRAL databases until August 2021; references were searched to identif...
Source: Cancer Control - April 8, 2022 Category: Cancer & Oncology Authors: Wilson A Wijaya Yu Liu Yong Qing Zhengyong Li Source Type: research
