Filtered By:
Cancer: Lymphoma

This page shows you your search results in order of relevance. This is page number 2.

Order by Relevance | Date

Total 25227 results found since Jan 2013.

Development of a Questionnaire for the Search for Occupational Causes in Patients with Non-Hodgkin Lymphoma: The RHELYPRO Study
In conclusion, this questionnaire appears as a useful tool to identify NHL patients for a specialized consultation, in order to ask for compensation for occupational disease.PMID:33920383 | DOI:10.3390/ijerph18084008
Source: Clinical Lymphoma and Myeloma - April 30, 2021 Category: Cancer & Oncology Authors: Mireille Matrat Murielle Gain Corinne Haioun Fabien Le Bras Catherine Nisse Franck Morschhauser B énédicte Clin Isabelle Baldi Catherine Verdun-Esquer Robert Garnier Herv é Laborde-Castérot Fabrice H érin Yolande Esquirol Pascal Andujar Milia Belacel Source Type: research

Seleno-vs. thioether triazine derivatives in search for new anticancer agents overcoming multidrug resistance in lymphoma
Eur J Med Chem. 2022 Sep 19;243:114761. doi: 10.1016/j.ejmech.2022.114761. Online ahead of print.ABSTRACTLymphomas are still difficult to treat even with modern therapies as, among others, multidrug resistance (MDR) is often counteracting a successful cancer therapy. P-gp/ABC-transporters are well-known for their crucial role in the main tumour MDR mechanism, eliminating drugs and cytotoxic substances from the cancer cell by efflux, and their modulators are promising for innovative therapy, but none has been approved in the pharmaceutical market yet. Herein, we have designed, synthesised and analysed 30 novel seleno- and t...
Source: European Journal of Medicinal Chemistry - September 30, 2022 Category: Chemistry Authors: Wesam Ali Sabrina Garbo Annam ária Kincses M árta Nové Gabriella Spengler Elisabetta Di Bello Ewelina Honkisz-Orzechowska Tadeusz Karcz Ewa Szyma ńska Ewa Żesławska Ma łgorzata Starek Monika D ąbrowska Wojciech Nitek Katarzyna Kucwaj-Brysz Patryk Source Type: research

Chimeric antigen receptor (CAR) T-cell therapy for people with relapsed or refractory diffuse large B-cell lymphoma
CONCLUSIONS: The available evidence on the benefits and harms of CAR T-cell therapy for people with r/r DLBCL is limited, mainly because of the absence of comparative clinical trials. The results we present should be regarded in light of this limitation and conclusions should be drawn very carefully. Due to the uncertainty in the current evidence, a large number of ongoing investigations and a risk of substantial and potentially life-threatening complications requiring supplementary treatment, it is critical to continue evaluating the evidence on this new therapy.PMID:34515338 | DOI:10.1002/14651858.CD013365.pub2
Source: Cochrane Database of Systematic Reviews - September 13, 2021 Category: General Medicine Authors: Moritz Ernst Annika Oeser Burcu Besiroglu Julia Caro-Valenzuela Mohamed Abd El Aziz Ina Monsef Peter Borchmann Lise J Estcourt Nicole Skoetz Marius Goldkuhle Source Type: research

Association Between Cancer Incidence and Mortality in Web-Based Data in China: Infodemiology Study
Conclusions: Search behaviors indeed reflect public awareness of cancer from a different angle. Research on internet search behaviors could present an innovative and timely way to monitor and estimate cancer incidence and mortality rates, especially for cancers not included in national registries.
Source: Journal of Medical Internet Research - January 29, 2019 Category: General Medicine Authors: Chenjie Xu Yi Wang Hongxi Yang Jie Hou Li Sun Xinyu Zhang Xinxi Cao Yabing Hou Lan Wang Qiliang Cai Yaogang Wang Source Type: research

A Systematic Review on Predisposition to Lymphoid (B and T cell) Neoplasias in Patients With Primary Immunodeficiencies and Immune Dysregulatory Disorders (Inborn Errors of Immunity)
Conclusions Though this is not a comprehensive summary of malignancies in PIDDs, or even lymphoproliferative disease in this area, this review summarizes the Medline-indexed published reports of B and T lymphomas in patients with PIDDs. This report highlights the diversity of malignant lymphoproliferative disorders in setting of PIDDs, and its associated challenges of diagnosis and treatment. The pathological classification and nomenclature for the lymphoid malignancies with variably reported and postulated underlying mechanisms were inconsistent and inadequate for many of these published reports. A wide range of treatmen...
Source: Frontiers in Immunology - April 15, 2019 Category: Allergy & Immunology Source Type: research

Efficacy and safety of autologous hematopoietic stem cell transplantation in the treatment of malignant lymphoma after chemotherapy: a systematic review and meta-analysis
DISCUSSION: AHSCT treatment can significantly prolong the overall survival and progression-free survival rates of patients with malignant lymphoma after chemotherapy.PMID:35571654 | PMC:PMC9091041 | DOI:10.21037/tcr-22-595
Source: Cell Research - May 16, 2022 Category: Cytology Authors: Huan Yu Limei Fu Xin Liao Amin Lei Yili Chen Ping Zhu Pingan Zhu Qiaojing Shi Source Type: research

Human Health Effects of Dichloromethane: Key Findings and Scientific Issues
Conclusion: The 2011 IRIS assessment of dichloromethane provides insights into the toxicity of a commonly used solvent. Citation: Schlosser PM, Bale AS, Gibbons CF, Wilkins A, Cooper GS. 2015. Human health effects of dichloromethane: key findings and scientific issues. Environ Health Perspect 123:114–119; http://dx.doi.org/10.1289/ehp.1308030 Address correspondence to G.S. Cooper, National Center for Environmental Assessment (8601-P), U.S. Environmental Protection Agency, 1200 Pennsylvania Ave. NW, Washington, DC 20460 USA. Telephone: (703) 347-8636. E-mail: Cooper.Glinda@epa.gov The views expressed are thos...
Source: EHP Research - February 2, 2015 Category: Environmental Health Authors: Web Admin Tags: Commentary February 2015 Source Type: research

Salt-Tolerant Antifungal and Antibacterial Activities of the Corn Defensin ZmD32
We examined whether the high charge on ZmD32 would allow this defensin to retain activity in media with elevated salt concentrations. ZmD32 inhibited C. albicans, C. auris, C. glabrata, C. krusei, C. parapsilosis, and C. tropicalis growth with IC50 values ranging from 0.7 to 3.0 in ½ PDB medium containing 100 mM NaCl. In contrast, NaD1 was only active against C. parapsilosis and C. tropicalis with IC50 values of 3.4 and 1.3 μM, respectively, in medium with added NaCl. ZmD32 also retained activity against E. coli when NaC1 concentrations were raised to 100 mM while NaD1 did not (Table 1). For C. albicans and C...
Source: Frontiers in Microbiology - April 11, 2019 Category: Microbiology Source Type: research

Effective generation of glucosylpiericidins with selective cytotoxicities and insights into their biosynthesis
In this study, five new piericidin glycosides (compounds 3, 4, 6, 7, and 8) were generated following the overexpression of GT-coding genes in a piericidin producer. Three of them (compounds 4, 7 and 8) displayed cytotoxic selectivity. Notably, GT1507 was demonstrated to be related to piericidin glucosylation in vivo Furthermore, mining of GT1507 homologs from the GenBank database revealed their wide distribution across numerous bacteria. Our findings would greatly facilitate the exploration of GTs to glycodiversify small molecules in the search of drug candidates.PMID:33893110 | DOI:10.1128/AEM.00294-21
Source: Applied and Environmental Microbiology - April 24, 2021 Category: Microbiology Authors: Zengzhi Liu Fei Xiao Siqi Cai Chunni Liu Huayue Li Ting Wu Yuechen Jiang Xin Wang Qian Che Tianjiao Zhu Dehai Li Wenli Li Source Type: research