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Specialty: Urology & Nephrology
Cancer: Ureter and Renal Pelvis Cancer

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Total 2164 results found since Jan 2013.

Medical treatment of urinary stones
Purpose of review To identify the latest progression on medical treatment of urinary stones. Recent findings Nonsteroidal anti-inflammatory drugs should be the preferred analgesic option for patients presenting to the emergency department with renal colic. A-blockers could be of patient benefit when used for distal ureteral stones more than 5 mm in size. However, the quality of the randomized controlled studies on medical expulsive therapy (MET) is still low based on the Consolidated Standards for Reporting Trials (CONSORT) criteria. MET should be used with caution in children and pregnant women. In patients with re...
Source: Current Opinion in Urology - July 31, 2018 Category: Urology & Nephrology Tags: PREVENTION OF UROLOGIC CALCULI - BEHAVIOURAL, DIETARY, AND MEDICAL ASPECTS: Edited by Evangelos Liatsikos and Margaret Pearle Source Type: research

Comparison of current guidelines on medical management of stone disease.
CONCLUSIONS: Despite methodological heterogeneity and subjective rating of recommendations, an acceptable degree of consensus was noted on Guidelines regarding medical management of stone disease. PMID: 33459633 [PubMed - in process]
Source: Archivos Espanoles de Urologia - January 21, 2021 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Comparison of silodosin to tamsulosin for medical expulsive treatment of ureteral stones: a systematic review and meta-analysis
This study aimed at comparing the success rates of silodosin to the most commonly used for medical expulsive therapy (MET) tamsulosin for the management of ureteral stones. A systematic review using the search string: “silodosin AND (ston* OR calcu* OR expul*)” was conducted on Pubmed, SCOPUS, Web of Science, Cochrane Central Register. The Primary endpoint was the stone expulsion rate. Secondary endpoint was the time to stone expulsion. Two authors independently screened the studies depending on inclusion and exclusion criteria. Meta-analysis and forest-plot figures were calculated with the software Review Manager (Rev...
Source: Urolithiasis - March 27, 2016 Category: Urology & Nephrology Source Type: research

Efficacy and safety of tamsulosin in the medical expulsion therapy for distal ureteral calculi: a systematic review and meta-analysis of a placebo-controlled trial.
CONCLUSION: The results of the current meta-analysis indicated that tamsulosin was superior to placebo in its efficacy for distal ureteral stones though retrograde ejaculation was worse with tamsulosin use. It should be a safe and effective medical expulsive therapy choice for distal ureteral stones when stone sizes are less than 10 mm. PMID: 31004338 [PubMed - as supplied by publisher]
Source: Urology Journal - April 19, 2019 Category: Urology & Nephrology Authors: Tao RZ, Qin ZQ, Liu FD, Lv JL Tags: Urol J Source Type: research

Medical expulsive treatment for ureteral stones.
CONCLUSIONS: Higher quality clinical trials are needed to reliably advice MET. With the current evidence, it appears that MET can improve the expulsion of distal ureteral lithiasis ≥ 5 mm and ≤ 10 mm, even though we have not found differences between the drugs that are available for MET. PMID: 33459624 [PubMed - in process]
Source: Archivos Espanoles de Urologia - January 21, 2021 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Medical Expulsive Therapy for Urinary Stones: Future Trends and Knowledge Gaps
ConclusionsThe strength of evidence for the benefit of MET in ureteral stones is low, even for distal ureteral stones>5 mm. In the absence of further high-quality data, individual clinicians are required to decide for themselves whether to believe high-quality single trials or meta-analyses.Patient summaryWe evaluated the value of and future directions for medical expulsive therapy (MET) for ureteral stone disease. We found that outcomes varied between studies. Individual clinicians are required to decide for themselves which studies to believe. Alpha-blockers as MET may retain a role in a selective group of well-counsel...
Source: European Urology - August 15, 2019 Category: Urology & Nephrology Source Type: research

Adjunctive medical expulsive therapy with tamsulosin for repeated extracorporeal shock wave lithotripsy: a systematic review and meta-analysis
Conclusion: Adjunctive MET with tamsulosin is effective in patients with specific stone size or location that received repeated ESWL. However, no well-designed RCT that used computed tomography for the detection and assessment of residual stone fragments was found. More studies with high quality and the comparison between tamsulosin and secondary ESWL are needed in the future.
Source: International Braz J Urol - November 18, 2020 Category: Urology & Nephrology Source Type: research

Fragility index of urological literature regarding medical expulsive treatment
ConclusionsIn this analysis, a calculated FI of 3.5 indicates that findings from RCTs on MET for ureteral stones are fragile and should be interpreted in combination with clinical thinking and expertise.
Source: World Journal of Urology - May 12, 2021 Category: Urology & Nephrology Source Type: research

Silodosin as a medical expulsive therapy for distal ureteral stones: A systematic review and meta-analysis
Conclusion: Silodosin showed significantly higher SER, lower SET and lower analgesic use in patients with distal ureteral stones as compared to a placebo.
Source: Indian Journal of Urology - December 29, 2022 Category: Urology & Nephrology Authors: Muhammad Zaniar Ramadhani Yudhistira Pradnyan Kloping Ilham Akbar Rahman Niwanda Yogiswara Mohammad Ayodhia Soebadi Johan Renaldo Source Type: research

Renal trauma in adolescent skateboarders.
CONCLUSIONS: We would emphasize these cases as an emergent urological warning. Scientific information and medical education should be addressed from physicians to a targeted population, in order to reduce among teens the incidence of injuries of such at-risk activity. PMID: 27845699 [PubMed - in process]
Source: Archivos Espanoles de Urologia - November 17, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Usefulness of personalized three-dimensional printed model on the satisfaction of preoperative education for patients undergoing robot-assisted partial nephrectomy and their families
ConclusionOur data indicate that the personalized 3D printed model of the kidney is useful for preoperative education among patients and their families who underwent RAPN, especially in elderly people.
Source: International Urology and Nephrology - May 9, 2018 Category: Urology & Nephrology Source Type: research

Medical Treatment and Prevention of Urinary Stone Disease
Urol Clin North Am. 2022 May;49(2):335-344. doi: 10.1016/j.ucl.2021.12.007.ABSTRACTThe pathophysiology underlying urinary stone formation remains an area of active investigation. There are many pharmacotherapies aimed at optimizing metabolic factors and reducing urinary supersaturation of stone components that play an important role in urinary stone prevention. In addition, medical expulsive therapy for ureteral stones and medical dissolution therapy for uric acid-based urinary stones are helpful treatment tools and are used alongside surgical treatments in the management of urinary stones.PMID:35428438 | DOI:10.1016/j.ucl.2021.12.007
Source: The Urologic Clinics of North America - April 16, 2022 Category: Urology & Nephrology Authors: Kyle Spradling Calyani Ganesan Simon Conti Source Type: research