Re: Robert A. Huddart, Emma Hall, Rebecca Lewis, et al. Patient-reported Quality of Life Outcomes in Patients Treated for Muscle-invasive Bladder Cancer with Radiotherapy ± Chemotherapy in the BC2001 Phase III Randomised Controlled Trial. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2019.11.001
Publication date: Available online 26 February 2020Source: European UrologyAuthor(s): Wei Liu, Xiaoping Liu, Sheng Li (Source: European Urology)
Source: European Urology - February 27, 2020 Category: Urology & Nephrology Source Type: research

Re: Ola Bratt, Erik Holmberg, Ove Andrén, et al. The Value of an Extensive Transrectal Repeat Biopsy with Anterior Sampling in Men on Active Surveillance for Low-risk Prostate Cancer: A Comparison from the Randomised Study of Active Monitoring in Sweden (SAMS). Eur Urol 2019;76:461–6
Publication date: Available online 25 February 2020Source: European UrologyAuthor(s): Francesco Montorsi, Giorgio Gandaglia, Nicola Fossati, Andrea Salonia, Alberto Briganti (Source: European Urology)
Source: European Urology - February 26, 2020 Category: Urology & Nephrology Source Type: research

Exploring Variation in the Use of Conservative Management for Low-risk Prostate Cancer in the Veterans Affairs Healthcare System
Publication date: Available online 22 February 2020Source: European UrologyAuthor(s): Stacy Loeb, Nataliya K. Byrne, Binhuan Wang, Danil V. Makarov, Daniel Becker, David R. Wise, Herbert Lepor, Dawn WalterAbstractCurrent guidelines recommend conservative management as the preferred option for most low-risk prostate cancer cases, with certain possible exceptions (age
Source: European Urology - February 23, 2020 Category: Urology & Nephrology Source Type: research

Re: Impact of Resection Technique on Perioperative Outcomes and Surgical Margins After Partial Nephrectomy for Localized Renal Masses: A Prospective Multicenter Study
Publication date: Available online 22 February 2020Source: European UrologyAuthor(s): Alberto Breda, Angelo Territo (Source: European Urology)
Source: European Urology - February 23, 2020 Category: Urology & Nephrology Source Type: research

Development and Internal Validation of a Web-based Tool to Predict Sexual, Urinary, and Bowel Function Longitudinally After Radiation Therapy, Surgery, or Observation
ConclusionsFunctional outcomes after treatment for localized prostate cancer can be predicted at the time of diagnosis based on age, race, PSA, biopsy grade, baseline function, and a general question regarding overall health. Providers and patients can use this prediction tool to inform shared decision making.Patient summaryIn this report, we studied patient-reported sexual, urinary, hormonal, and bowel function through 5 yr after treatment with radical prostatectomy, radiation therapy, or active surveillance for localized prostate cancer. We developed a web-based predictive tool that can be used to predict one’s o...
Source: European Urology - February 23, 2020 Category: Urology & Nephrology Source Type: research

Re: Frank-Jan H. Drost, Daniel Osses, Daan Nieboer, et al. Prostate Magnetic Resonance Imaging, with or Without Magnetic Resonance Imaging-targeted Biopsy, and Systematic Biopsy for Detecting Prostate Cancer: A Cochrane Systematic Review and Meta-analysis. Eur Urol 2020;77:78–94: Are Targeted Prostate Biopsies Enough in Men with a Previous Negative Biopsy?
Publication date: Available online 20 February 2020Source: European UrologyAuthor(s): Juan Morote, Anna Celma, Jacques Planas (Source: European Urology)
Source: European Urology - February 21, 2020 Category: Urology & Nephrology Source Type: research

Re: Maria Chiara Sighinolfi, Bernardo Rocco’s Words of Wisdom re: EAU Guidelines: Prostate Cancer 2019. Mottet N, van den Bergh RCN, Briers E, et al. https://uroweb.org/guideline/prostate-Cancer/. Eur Urol 2019;76:871
Publication date: Available online 20 February 2020Source: European UrologyAuthor(s): Alessia Cimadamore, Marina Scarpelli, Liang Cheng, Antonio Lopez-Beltran, Andrea B. Galosi, Francesco Montorsi, Rodolfo Montironi (Source: European Urology)
Source: European Urology - February 21, 2020 Category: Urology & Nephrology Source Type: research

Orsi Consensus Meeting on European Robotic Training (OCERT): Results from the First Multispecialty Consensus Meeting on Training in Robot-assisted Surgery
Publication date: Available online 21 February 2020Source: European UrologyAuthor(s): Aude E. Vanlander, Elio Mazzone, Justin W. Collins, Alexandre M. Mottrie, Xavier M. Rogiers, Henk G. van der Poel, Isabelle Van Herzeele, Richard M. Satava, Anthony G. GallagherAbstractTo improve patient outcomes in robotic surgery, robotic training and education need to be modernised and augmented. The skills and performance levels of trainees need to be objectively assessed before they operate on real patients. The main goal of the first Orsi Consensus Meeting on European Robotic Training (OCERT) was to establish the opinions of experts...
Source: European Urology - February 21, 2020 Category: Urology & Nephrology Source Type: research

Radical Prostatectomy or Observation for Clinically Localized Prostate Cancer: Extended Follow-up of the Prostate Cancer Intervention Versus Observation Trial (PIVOT)
This study evaluated long-term follow-up of a randomized trial conducted at the US Department of Veterans Affairs and National Cancer Institute sites. The participants were men (n = 731) ≤75 yr of age with localized prostate cancer, prostate-specific antigen (PSA)
Source: European Urology - February 21, 2020 Category: Urology & Nephrology Source Type: research

Salvage Treatment for Biochemical Failure After Radical Prostatectomy: Do We Now Have the Answers?
Publication date: Available online 18 February 2020Source: European UrologyAuthor(s): Andrew Kneebone, Sarah Bergamin (Source: European Urology)
Source: European Urology - February 20, 2020 Category: Urology & Nephrology Source Type: research

Reply to Alessia Cimadamore, Marina Scarpelli, Liang Cheng, et al’s Letter to the Editor, re: Maria Chiara Sighinolfi, Bernardo Rocco’s Words of Wisdom re: EAU Guidelines: Prostate Cancer 2019. Mottet N, van den Bergh RCN, Briers E, et al. https://uroweb.org/guideline/prostate-Cancer/. Eur Urol 2019, 76:871
Publication date: Available online 14 February 2020Source: European UrologyAuthor(s): Maria Chiara Sighinolfi, Bernardo Rocco (Source: European Urology)
Source: European Urology - February 15, 2020 Category: Urology & Nephrology Source Type: research

Seeking the Truth: Understanding the Impact of Missing Data on the Validity of the New Surveillance, Epidemiology and End Results Prostate with Watchful Waiting Database
Publication date: Available online 12 February 2020Source: European UrologyAuthor(s): Aaron A. Laviana, Amy N. Luckenbaugh, Christopher J.D. Wallis (Source: European Urology)
Source: European Urology - February 14, 2020 Category: Urology & Nephrology Source Type: research

Re: Transcriptomic Signatures Related to the Obesity Paradox in Patients with Clear Cell Renal Cell Carcinoma: A Cohort Study
Publication date: Available online 13 February 2020Source: European UrologyAuthor(s): Cissy Yong, Grant D. Stewart (Source: European Urology)
Source: European Urology - February 14, 2020 Category: Urology & Nephrology Source Type: research

The Importance of Standardised Recording of Intraoperative Adverse Events: Key Features of an Ideal Classification System
Publication date: Available online 13 February 2020Source: European UrologyAuthor(s): Salome Dell-Kuster, Cyrill A. Rentsch, Luzius A. Steiner, Rachel Rosenthal (Source: European Urology)
Source: European Urology - February 14, 2020 Category: Urology & Nephrology Source Type: research

Editorial Board
Publication date: March 2020Source: European Urology, Volume 77, Issue 3Author(s): (Source: European Urology)
Source: European Urology - February 14, 2020 Category: Urology & Nephrology Source Type: research

The Platinum Hall of Fame
Publication date: March 2020Source: European Urology, Volume 77, Issue 3Author(s): (Source: European Urology)
Source: European Urology - February 14, 2020 Category: Urology & Nephrology Source Type: research

Contents
Publication date: March 2020Source: European Urology, Volume 77, Issue 3Author(s): (Source: European Urology)
Source: European Urology - February 14, 2020 Category: Urology & Nephrology Source Type: research

Congress Calendar
Publication date: March 2020Source: European Urology, Volume 77, Issue 3Author(s): (Source: European Urology)
Source: European Urology - February 14, 2020 Category: Urology & Nephrology Source Type: research

Reply To Kenneth B. Yatai, Mark J. Dunning, Dennis Wang. Consensus Genomic Subtypes of Muscle-invasive Bladder Cancer: A Step in the Right Direction but Still a Long Way To Go. Eur Urol. In press
Publication date: Available online 7 February 2020Source: European UrologyAuthor(s): Aurélie Kamoun, Aurélien de Reyniès, Yves Allory, Gottfrid Sjödahl, A. Gordon Robertson, Roland Seiler, Katherine A. Hoadley, Clarice S. Groeneveld, Hikmat Al-Ahmadie, Woonyoung Choi, Mauro A.A. Castro, Jacqueline Fontugne, Pontus Eriksson, Qianxing Mo, Jordan Kardos, Alexandre Zlotta, Arndt Hartmann, Colin P Dinney, Joaquim Bellmunt, Thomas Powles (Source: European Urology)
Source: European Urology - February 8, 2020 Category: Urology & Nephrology Source Type: research

Docetaxel for Early Prostate Cancer: What Have We Learned?
Publication date: Available online 7 February 2020Source: European UrologyAuthor(s): Himisha Beltran, Michael J. Morris (Source: European Urology)
Source: European Urology - February 8, 2020 Category: Urology & Nephrology Source Type: research

Re: Validation of the Endoscopic Stone Treatment Step 1 (EST-s1): A Novel EAU Training and Assessment Tool for Basic Endoscopic Stone Treatment Skills—A Collaborative Work by ESU, ESUT and EULIS
Publication date: Available online 7 February 2020Source: European UrologyAuthor(s): Jens Rassweiler (Source: European Urology)
Source: European Urology - February 8, 2020 Category: Urology & Nephrology Source Type: research

Re: Aurélie De Bruycker, Elise De Bleser, Karel Decaestecker, et al. Nodal Oligorecurrent Prostate Cancer: Anatomic Pattern of Possible Treatment Failure in Relation to Elective Surgical and Radiotherapy Treatment Templates. Eur Urol 2019;75:826–33: Nodal Recurrence of Prostate Cancer in Patients Treated with Radical Intent: Tailoring the Best Salvage Treatment
Publication date: Available online 7 February 2020Source: European UrologyAuthor(s): Francesco Montorsi, Nicola Fossati, Giorgio Gandaglia, Alberto Briganti (Source: European Urology)
Source: European Urology - February 8, 2020 Category: Urology & Nephrology Source Type: research

Re: Medium-term Oncologic Outcomes in a Large Cohort of Men Treated with Focal or Hemi-ablation Using High-intensity Focused Ultrasonography for Primary Localized Prostate Cancer
Publication date: Available online 6 February 2020Source: European UrologyAuthor(s): John W. Davis (Source: European Urology)
Source: European Urology - February 6, 2020 Category: Urology & Nephrology Source Type: research

Re:Intraoperative Near-Infrared Imaging Can Identify Neoplasms and Aid in Real-time Margin Assessment During Pancreatic Resection
Publication date: Available online 3 February 2020Source: European UrologyAuthor(s): Begoña Ballesta Martínez, Karim Touijer (Source: European Urology)
Source: European Urology - February 5, 2020 Category: Urology & Nephrology Source Type: research

Re:Cabazitaxel Versus Abiraterone or Enzalutamide in Metastatic Prostate Cancer
Publication date: Available online 3 February 2020Source: European UrologyAuthor(s): Jose Rubio-Briones (Source: European Urology)
Source: European Urology - February 5, 2020 Category: Urology & Nephrology Source Type: research

Re: Clinical Efficacy and Biomarker Analysis of Neoadjuvant Atezolizumab in Operable Urothelial Carcinoma in the ABACUS Trial
Publication date: Available online 3 February 2020Source: European UrologyAuthor(s): Gerald B. Schulz, Peter C. Black (Source: European Urology)
Source: European Urology - February 5, 2020 Category: Urology & Nephrology Source Type: research

Are the Role of Surgery and its Complications Sufficiently Focused in the Era of Perioperative Systemic Treatments?
Publication date: Available online 29 January 2020Source: European UrologyAuthor(s): Marko Babjuk (Source: European Urology)
Source: European Urology - January 30, 2020 Category: Urology & Nephrology Source Type: research

Reply to Charalampos Fragkoulis, Georgios Papadopoulos, and Konstantinos Ntoumas’s Letter to the Editor re: Francesco Del Giudice, Giovanni Barchetti, Ettore De Berardinis, et al. Prospective Assessment of Vesical Imaging Reporting and Data System (VI-RADS) and its Clinical Impact on the Management of High-risk Non–muscle-invasive Bladder Cancer Patients Candidate for Repeated Transurethral Resection. Eur Urol 2020;77:101–9
Publication date: Available online 28 January 2020Source: European UrologyAuthor(s): Francesco Del Giudice, James W.F. Catto, Valeria Panebianco (Source: European Urology)
Source: European Urology - January 29, 2020 Category: Urology & Nephrology Source Type: research

Treatment Choices for Front-line Metastatic Clear Cell Renal Cancer
Publication date: Available online 28 January 2020Source: European UrologyAuthor(s): Thomas Powles (Source: European Urology)
Source: European Urology - January 29, 2020 Category: Urology & Nephrology Source Type: research

Management of Patients with Advanced Prostate Cancer: Report of the Advanced Prostate Cancer Consensus Conference 2019
ConclusionsThese voting results from a panel of prostate cancer experts can help clinicians and patients navigate controversial areas of advanced prostate management for which high-level evidence is sparse. However, diagnostic and treatment decisions should always be individualised based on patient-specific factors, such as disease extent and location, prior lines of therapy, comorbidities, and treatment preferences, together with current and emerging clinical evidence and logistic and economic constraints. Clinical trial enrolment for men with advanced prostate cancer should be strongly encouraged. Importantly, APCCC 2019...
Source: European Urology - January 28, 2020 Category: Urology & Nephrology Source Type: research

European Association of Urology Guidelines Office: How We Ensure Transparent Conflict of Interest Disclosure and Management
Publication date: Available online 25 January 2020Source: European UrologyAuthor(s): Emma Jane Smith, Karin Plass, Julie Darraugh, Robert Shepherd, Alberto Briganti, Philip Cornford, Thomas Knoll, Nicolaas Lumen, James N’Dow, Maria J. Ribal, Richard Sylvester, Hendrik van Poppel, Anders Bjartell, the EAU Guidelines Office Panel Chairs (Source: European Urology)
Source: European Urology - January 26, 2020 Category: Urology & Nephrology Source Type: research

The Pillars for Sustained Growth of Magnetic Resonance Imaging Pathway for Prostate Cancer Diagnosis: Quality, Reproducibility, Accessibility, Cost Effectiveness, and Training
Publication date: Available online 23 January 2020Source: European UrologyAuthor(s): Andre Luis Abreu (Source: European Urology)
Source: European Urology - January 23, 2020 Category: Urology & Nephrology Source Type: research

The New Surveillance, Epidemiology, and End Results Prostate with Watchful Waiting Database: Opportunities and Limitations
Publication date: Available online 21 January 2020Source: European UrologyAuthor(s): Chang Wook Jeong, Samuel L. Washington, Annika Herlemann, Scarlett L. Gomez, Peter R. Carroll, Matthew R. CooperbergAbstractBackgroundActive surveillance (AS)/watchful waiting (WW) strategy for localized prostate cancer (PCa) is increasingly and broadly endorsed as a preferred option for initial treatment of men with very low- and low-risk PCa, but outcomes can be difficult to analyze in traditional, population-based registries. The recently released Surveillance, Epidemiology, and End Results (SEER) Prostate with WW dataset provides an op...
Source: European Urology - January 22, 2020 Category: Urology & Nephrology Source Type: research

Re: Taylor P. Kohn, Jaden R. Kohn, Ryan C. Owen, R. Matthew Coward. The Prevalence of Y-chromosome Microdeletions in Oligozoospermic Men: A Systematic Review and Meta-analysis of European and North American Studies. Eur Urol 2019;76:626–36: Indication for Y Chromosome Microdeletion Analysis in Infertile Men Should Not be Based Merely on Sperm Concentration
Publication date: Available online 21 January 2020Source: European UrologyAuthor(s): Alberto Ferlin (Source: European Urology)
Source: European Urology - January 22, 2020 Category: Urology & Nephrology Source Type: research

Reply to Alberto Ferlin’s Letter to the Editor, re: Taylor P. Kohn, Jaden R. Kohn, Ryan C. Owen, R. Matthew Coward. The Prevalence of Y-chromosome Microdeletions in Oligozoospermic Men: A Systematic Review, Meta-analysis of European, North American Studies. Eur Urol 2019, 76:626–36. Indication for Y Chromosome Microdeletion Analysis in Infertile Men Should Not be, Based Merely on Sperm Concentration: Shared Decision-Making and Reconsideration of Thresholds for Genetic Testing of Men with Severe Spermatogenic Failure
Publication date: Available online 21 January 2020Source: European UrologyAuthor(s): Taylor P. Kohn, Jaden R. Kohn, Ryan C. Owen, R. Matthew Coward (Source: European Urology)
Source: European Urology - January 22, 2020 Category: Urology & Nephrology Source Type: research

Re: Veeru Kasivisvanathan, Armando Stabile, Joana B. Neves, et al. Magnetic Resonance Imaging-targeted Biopsy Versus Systematic Biopsy in the Detection of Prostate Cancer: A Systematic Review and Meta-analysis. Eur Urol 2019;76:284–303: Threshold Indication for Magnetic Resonance Imaging–targeted Biopsy in the Detection of Prostate Cancer
Publication date: Available online 21 January 2020Source: European UrologyAuthor(s): Jae Heon Kim, In Gab Jeong (Source: European Urology)
Source: European Urology - January 22, 2020 Category: Urology & Nephrology Source Type: research

Re: Felix Preisser, Felix K.H. Chun, Raisa S. Pompe, et al. Persistent Prostate-Specific Antigen After Radical Prostatectomy and Its Impact on Oncologic Outcomes. Eur Urol 2019;76:106–14
Publication date: Available online 21 January 2020Source: European UrologyAuthor(s): Francesco Montorsi, Nicola Fossati, Giorgio Gandaglia, Alberto Briganti (Source: European Urology)
Source: European Urology - January 22, 2020 Category: Urology & Nephrology Source Type: research

Corrigendum re “Periurethral Injection of Autologous Adipose-Derived Stem Cells with Controlled-Release Nerve Growth Factor for the Treatment of Stress Urinary Incontinence in a Rat Model” [Eur Urol 2011;59:155–63]
Publication date: Available online 21 January 2020Source: European UrologyAuthor(s): Weiming Zhao, Cheng Zhang, Chengjun Jin, Zijian Zhang, Deling Kong, Wanhai Xu, Youcheng Xiu (Source: European Urology)
Source: European Urology - January 22, 2020 Category: Urology & Nephrology Source Type: research

Re: Francesco Del Giudice, Giovanni Barchetti, Ettore De Berardinis, et al. Prospective Assessment of Vesical Imaging Reporting and Data System (VI-RADS) and Its Clinical Impact on the Management of High-risk Non–muscle-invasive Bladder Cancer Patients Candidate for Repeated Transurethral Resection. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2019.09.029
Publication date: Available online 21 January 2020Source: European UrologyAuthor(s): Charalampos Fragkoulis, Georgios Papadopoulos, Konstantinos Ntoumas (Source: European Urology)
Source: European Urology - January 22, 2020 Category: Urology & Nephrology Source Type: research

Leveraging Behavioral Economics to Reduce Low-value Prostate Cancer Screening
Publication date: Available online 17 January 2020Source: European UrologyAuthor(s): Trevor C. Hunt, Brock B. O’Neil (Source: European Urology)
Source: European Urology - January 18, 2020 Category: Urology & Nephrology Source Type: research

Technical Modifications Necessary to Implement the da Vinci Single-port Robotic System
ConclusionsRARP with the da Vinci SP is feasible and safe. Therefore, the step-by-step technique described in this study could be considered an option to perform radical prostatectomies. However, we still need better-designed studies to compare the outcomes with those of the multiport platform.Patient summaryWe reported our step-by-step technique describing a safe approach to robotic-assisted radical prostatectomy during the transition from the Xi to the da Vinci single-port robot. (Source: European Urology)
Source: European Urology - January 18, 2020 Category: Urology & Nephrology Source Type: research

Comparison of the Efficacy Between Transurethral Coagulation and Transurethral Resection of Hunner Lesion in Interstitial Cystitis/Bladder Pain Syndrome Patients: A Prospective Randomized Controlled Trial
Publication date: Available online 17 January 2020Source: European UrologyAuthor(s): Kwang Jin Ko, Won Jin Cho, Young-Suk Lee, Joongwon Choi, Hye Jin Byun, Kyu-Sung LeeAbstractBackgroundInterstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic condition characterized by chronic pelvic pain related to the bladder with no effective treatment options.ObjectiveTo evaluate the efficacy and safety of transurethral resection (TUR) and transurethral coagulation (TUC) as treatments for Hunner lesion (HL) in IC/BPS.Design, setting, and participantsA single-center, prospective, randomized controlled trial involving 126 patien...
Source: European Urology - January 18, 2020 Category: Urology & Nephrology Source Type: research

Comprehensive Assessment of Immuno-oncology Biomarkers in Adenocarcinoma, Urothelial Carcinoma, and Squamous-cell Carcinoma of the Bladder
Publication date: Available online 17 January 2020Source: European UrologyAuthor(s): Andrea Necchi, Russell Madison, Daniele Raggi, Joseph M. Jacob, Gennady Bratslavsky, Oleg Shapiro, Julia A. Elvin, Jo-Anne Vergilio, Jonathan K. Killian, Nhu Ngo, Shakti Ramkissoon, Eric Severson, Amanda C. Hemmerich, Richard Huang, Siraj M. Ali, Jon H. Chung, Prasanth Reddy, Vincent A. Miller, Alexa B. Schrock, Laurie M. GayAbstractBackgroundIn patients with rare histologies of bladder cancer, including adenocarcinoma of the bladder (ACB) and squamous-cell carcinoma (SCC), there are limited standard therapy options, defining an unmet medi...
Source: European Urology - January 18, 2020 Category: Urology & Nephrology Source Type: research

Editorial Board
Publication date: February 2020Source: European Urology, Volume 77, Issue 2Author(s): (Source: European Urology)
Source: European Urology - January 17, 2020 Category: Urology & Nephrology Source Type: research

The Platinum Hall of Fame
Publication date: February 2020Source: European Urology, Volume 77, Issue 2Author(s): (Source: European Urology)
Source: European Urology - January 17, 2020 Category: Urology & Nephrology Source Type: research

Contents
Publication date: February 2020Source: European Urology, Volume 77, Issue 2Author(s): (Source: European Urology)
Source: European Urology - January 17, 2020 Category: Urology & Nephrology Source Type: research

Congress Calendar
Publication date: February 2020Source: European Urology, Volume 77, Issue 2Author(s): (Source: European Urology)
Source: European Urology - January 17, 2020 Category: Urology & Nephrology Source Type: research

Learning Curve in Robot-assisted Kidney Transplantation: Results from the European Robotic Urological Society Working Group
ConclusionsA minimum of 35 cases are necessary to reach reproducibility in terms of RWT, complications, and functional results.Patient summaryRobot-assisted kidney transplantation requires a learning curve of 35 cases to achieve reproducibility in terms of timing, complications, and functional results. Synergy between the surgeon and the assistant is crucial to reduce rewarming time. High-grade complications and delayed graft function are rare after ten surgeries. Hands-on training and proctorship are highly recommended. (Source: European Urology)
Source: European Urology - January 11, 2020 Category: Urology & Nephrology Source Type: research

The Singularity is Near(ish): Emerging Applications of Artificial Intelligence in Prostate Cancer Management
Publication date: Available online 8 January 2020Source: European UrologyAuthor(s): Joseph Chin, Glenn Bauman, Nicholas Power, Aaron Ward (Source: European Urology)
Source: European Urology - January 9, 2020 Category: Urology & Nephrology Source Type: research

Veterans Affairs Cooperative Studies Program Study #553: Chemotherapy After Prostatectomy for High-risk Prostate Carcinoma: A Phase III Randomized Study
ConclusionsAdjuvant chemotherapy in high-risk prostate cancer using docetaxel and prednisone did not lead to statistically significant improvement in PFS for the intention-to-treat population as a whole. The analysis was challenged by lower power due to accrual limitation. Subgroup analyses suggest potential benefit for patients with Gleason grade ≤7 and stage ≥ pT3b (ClinicalTrials.gov number NCT00132301).Patient summaryIn this randomized trial, we tested whether addition of chemotherapy to surgery for high-risk prostate cancer decreased the risk of prostate-specific antigen rise after surgery. We found no...
Source: European Urology - January 8, 2020 Category: Urology & Nephrology Source Type: research