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Total 412620 results found since Jan 2013.
ASO Author Reflections: Can Nodal Features Improve Treatment Response Prediction in Esophageal Cancer?
Ann Surg Oncol. 2023 Sep 20. doi: 10.1245/s10434-023-14299-1. Online ahead of print.NO ABSTRACTPMID:37731144 | DOI:10.1245/s10434-023-14299-1
Source: Ann Oncol - September 21, 2023 Category: Cancer & Oncology Authors: Kunwei Li Shuaitong Zhang Hong Shan Source Type: research
Risk factors of post-operation surgical site infection for gastric cancer patients underwent total gastrectomy
Asian J Surg. 2023 Sep 19:S1015-9584(23)01439-2. doi: 10.1016/j.asjsur.2023.09.054. Online ahead of print.NO ABSTRACTPMID:37734985 | DOI:10.1016/j.asjsur.2023.09.054
Source: Asian Journal of Surgery - September 21, 2023 Category: Surgery Authors: Chunhong Mu Ciba Zhu Ting Li Jichun Ma Source Type: research
Construction, evaluation, and AOP framework-based application of the EpPRS as a genetic surrogate for assessing environmental pollutants
CONCLUSIONS: EpPRSs can serve as a proxy for assessing pollutant internal exposure. The application of the EpPRS to disease risk assessment can reveal the toxic pathway and mode of action linking exposure and disease in detail, providing a basis for the development of environmental pollutant control strategies.PMID:37734146 | DOI:10.1016/j.envint.2023.108202
Source: Environment International - September 21, 2023 Category: Environmental Health Authors: Silu Chen Junyi Xin Zhutao Ding Lingyan Zhao Shuai Ben Rui Zheng Shuwei Li Huiqin Li Wei Shao Yifei Cheng Zhengdong Zhang Mulong Du Meilin Wang Source Type: research
Chronic Respiratory Diseases as a Risk Factor for Herpes Zoster Infection
CONCLUSIONS: In a standard clinical practice setting, the most prevalent respiratory diseases (asthma, COPD and lung cancer) are related to a higher risk of HZ and PHN. These data are fundamental to assess the potential impact of vaccination in this population.PMID:37734964 | DOI:10.1016/j.arbres.2023.08.010
Source: Archivos de Bronconeumologia - September 21, 2023 Category: Respiratory Medicine Authors: Diego Morena Sara Lumbreras Jos é Miguel Rodríguez Carolina Campos Mar ía Castillo Mar ía Benavent Jos é Luis Izquierdo Source Type: research
Par3L, a polarity protein, promotes M1 macrophage polarization and aggravates atherosclerosis in mice via p65 and ERK activation
In this study, we investigated the roles of the polar protein Par3L in M1 macrophage polarization and atherosclerosis. To induce atherosclerosis, Apoe-/- mice were fed with an atherosclerotic Western diet for 8 or 16 weeks. We showed that Par3L expression was significantly increased in human and mouse atherosclerotic plaques. In primary mouse macrophages, oxidized low-density lipoprotein (oxLDL, 50 μg/mL) time-dependently increased Par3L expression. In Apoe-/- mice, adenovirus-mediated Par3L overexpression aggravated atherosclerotic plaque formation accompanied by increased M1 macrophages in atherosclerotic plaques and bo...
Source: Acta Pharmacologica Sinica - September 21, 2023 Category: Drugs & Pharmacology Authors: Yi-Min Huang Yu-Sen Wu Yuan-Ye Dang Yi-Ming Xu Kong-Yang Ma Xiao-Yan Dai Source Type: research
Nutrition-associated health levels in persons with cancer: item response modelling based on the International Classification of Functioning, Disability and Health
CONCLUSIONS: The study constructed an evidence-based ICF scale for nutrition conditions in patients with cancer with 32-item and 2PLM for evaluating nutrition-associated health level in persons with cancer, including high validity and reliability.CLINICAL REHABILITATION IMPACT: The IRT model based on ICF provided a promising assessment tool to discriminate nutrition-associated health level of persons with cancer, and offered an auxiliary method for selecting rehabilitation intervention targets. This has the potential to lead to improved outcomes in cancer treatment and increased quality of life for cancer survivors.PMID:37...
Source: Methods of Information in Medicine - September 21, 2023 Category: Information Technology Authors: Jin-Jin Chen Zi-Yan Zhu Jia-Jia Bian Feng Lin Source Type: research
Colorectal polyp classification and management of complex polyps for surgeon endoscopists
Can J Surg. 2023 Sep 21;66(5):E491-E498. doi: 10.1503/cjs.011422. Print 2023 Sep-Oct.ABSTRACTSummaryIncreasing familiarity with advanced endoscopic excision techniques allows for more colorectal lesions to be removed without major surgery. Endoscopic excision with negative margins is adequate for most polyps and low-risk T1 cancers. The use of modern polyp classification techniques based on size, morphology and pit pattern by an experienced endoscopist allow for an optical diagnosis of these lesions and can predict, with high accuracy, which lesions contain malignant disease and the level of invasion. A surgeon endoscopist...
Source: Canadian Journal of Surgery - September 21, 2023 Category: Surgery Authors: Garrett G R J Johnson Ramzi Helewa Dana C Moffatt John Gerard Coneys Jason Park Eric Hyun Source Type: research
Circ_0005785 Silencing Constrains the Functional Properties of Colorectal Cancer Cells Depending on miR-7-5p/DNMT3A Axis
In conclusion, circ_0005785 aggravated the CRC progression by increasing the level of DNMT3A via adsorbing miR-7-5p.PMID:37730966 | DOI:10.1007/s10528-023-10522-6
Source: Biochemical Genetics - September 21, 2023 Category: Genetics & Stem Cells Authors: Zhu Li Gangling Tong Xiaodan Peng Shubin Wang Source Type: research
The Role of lncRNA-miR-26a-mRNA Network in Cancer Progression and Treatment
Biochem Genet. 2023 Sep 20. doi: 10.1007/s10528-023-10475-w. Online ahead of print.ABSTRACTThe role of non-coding RNAs in regulating biological processes associated with cancer progression, such as proliferation, migration, and apoptosis, has been extensively studied. Long non-coding RNAs (lncRNAs) play a role in regulating these processes through various mechanisms, including transcriptional and post-transcriptional modifications. In post-transcriptional regulation, lncRNAs can bind to specific miRNAs and affect their function, which can either promote or inhibit cancer development. The interaction between lncRNAs, miRNAs...
Source: Biochemical Genetics - September 21, 2023 Category: Genetics & Stem Cells Authors: Jun Zhu Liya Wang Source Type: research
Exosomal circKIAA1797 Regulates Cell Progression and Glycolysis by Targeting miR-4429/PBX3 Pathway in Gastric Cancer
Biochem Genet. 2023 Sep 20. doi: 10.1007/s10528-023-10529-z. Online ahead of print.ABSTRACTIn recent years, circular RNAs (circRNAs) are extensively studied in the progression of various types of cancer, while the mechanism of circKIAA1797 is rarely studied in gastric cancer (GC). Hence, this research aimed to investigate the expression of exosomal circKIAA1797 and its biological function in GC cells. Exosomes were extracted from the serum of GC patients and identified by transmission electron microscopy (TEM) and nanoparticle tracking analyzer (NTA). CD81, CD63, Bcl-2, Bax, and pre-leukemia transcription factor 3 (PBX3) p...
Source: Biochemical Genetics - September 21, 2023 Category: Genetics & Stem Cells Authors: Xiaomei Zheng Hongwei Xiao Xiaoxiao Liu Ting Huang Chengwei Deng Source Type: research
Quality of life following non-dysvascular lower limb amputation is contextualized through occupations: a qualitative study
CONCLUSION: The findings from this work can be leveraged by clinicians and researchers alike to improve care for this population. Rehabilitation programs should consider interventions and programming that help to restore occupations or develop new ones given the importance placed on occupations by persons with non-dysvascular LLA.PMID:37731381 | DOI:10.1080/09638288.2023.2258340
Source: Disability and Rehabilitation - September 21, 2023 Category: Rehabilitation Authors: Stephanie R Cimino Sander L Hitzig Vera Fung Katie N Dainty Crystal MacKay Joanna E M Sale Amanda L Mayo Sara J T Guilcher Source Type: research
Quality of life and nutritional status of a group of post-operative head and neck cancer patients
CONCLUSIONS: these results suggest that the use of EN in post-operative HNC patients could have a positive effect on the nutritional status and quality of life of these patients. However, further research is needed to optimize the nutritional support in these patients in order to avoid malnutrition and improve their well-being.PMID:37732341 | DOI:10.20960/nh.04638
Source: Nutricion Hospitalaria - September 21, 2023 Category: Nutrition Authors: Marta Tristan Asensi Ilaria Giangrandi Lorena Sartini Giuditta Pagliai Monica Dinu Sofia Lotti Barbara Colombini Francesco Sofi Source Type: research
Development and evaluation of the MiCheck ® Prostate test for clinically significant prostate cancer
CONCLUSIONS: The MiCheck® Prostate test identifies clinically significant prostate cancer with high sensitivity and negative predictive value (NPV). It can be performed in a clinical laboratory using a Roche Cobas clinical chemistry analyzer. The MiCheck® Prostate test could assist in reducing unnecessary prostate biopsies with a marginal number of patients experiencing a delayed diagnosis.PMID:37734979 | DOI:10.1016/j.urolonc.2023.08.005
Source: Urologic Oncology - September 21, 2023 Category: Urology & Nephrology Authors: Neal D Shore Dmitry M Polikarpov Christopher M Pieczonka R Jonathan Henderson James L Bailen Daniel R Saltzstein Raoul S Concepcion Jennifer L Beebe-Dimmer Julie J Ruterbusch Rachel A Levin Sandra Wissmueller Thao Ho Le David A Gillatt Daniel W Chan Niant Source Type: research
Nutrition-associated health levels in persons with cancer: item response modelling based on the International Classification of Functioning, Disability and Health
CONCLUSIONS: The study constructed an evidence-based ICF scale for nutrition conditions in patients with cancer with 32-item and 2PLM for evaluating nutrition-associated health level in persons with cancer, including high validity and reliability.CLINICAL REHABILITATION IMPACT: The IRT model based on ICF provided a promising assessment tool to discriminate nutrition-associated health level of persons with cancer, and offered an auxiliary method for selecting rehabilitation intervention targets. This has the potential to lead to improved outcomes in cancer treatment and increased quality of life for cancer survivors.PMID:37...
Source: European Journal of Physical and Rehabilitation Medicine - September 21, 2023 Category: Rehabilitation Authors: Jin-Jin Chen Zi-Yan Zhu Jia-Jia Bian Feng Lin Source Type: research
Disparities in Timeliness of Endometrial Cancer Care: A Scoping Review
CONCLUSIONS: Evidence gaps on disparities in timeliness of endometrial cancer care reveal emphasis of patient-driven help-seeking delays, reliance on health care-derived databases, underutilization of participatory methods, and a paucity of intervention studies.SYSTEMATIC REVIEW REGISTRATION: Given that PROSPERO was not accepting systematic scoping review protocols at the time this study began, this study protocol was shared a priori through Open Science Framework on January 13, 2021 (doi: 10.17605/OSF.IO/V2ZXY), and through peer review publication on April 13, 2021 (doi: https://doi.org/10.1186/s13643-021-01649-x).PMID:37...
Source: Obstetrics and Gynecology - September 21, 2023 Category: OBGYN Authors: Anna Najor Valerie Melson Junrui Lyu Priyal Fadadu Jamie Bakkum-Gamez Mark Sherman Andrew Kaunitz Avonne Connor Christopher Destephano Source Type: research
