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Cancer: Gastric (Stomach) Cancer

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Total 26716 results found since Jan 2013.

Alcohol Consumption and Gastric Cancer Risk: A Meta-Analysis.
CONCLUSIONS The results from this meta-analysis support the hypothesis that alcohol consumption can increase the risk of gastric cancer; suggesting that effective moderation of alcohol drinking may reduce the risk of gastric cancer. PMID: 28087989 [PubMed - in process]
Source: Medical Science Monitor - January 16, 2017 Category: Research Tags: Med Sci Monit Source Type: research

The diagnostic and prognostic values of microRNA-21 in patients with gastric cancer: a meta-analysis.
CONCLUSIONS: miR-21 can be used for the diagnosis of gastric cancer and prognosis of lymph node metastasis in gastric cancer. PMID: 28121346 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - January 27, 2017 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research

Clinical outcome and molecular characterization of brain metastases from esophageal and gastric cancer: a systematic review
AbstractThe aim of the study was to collect the available data on central nervous system (CNS) metastases from esophageal and gastric cancer. A PubMed, EMBASE, SCOPUS, Web of Science, LILACS, Ovid and Cochrane Library search was performed. Thirty-seven studies including 779 patients were considered. Among the data extracted, treatment of tumor and brain metastases (BMs), time to BMs development, number and subsite, extracerebral metastases rate, median overall survival (OS) and prognostic factors were included. For esophageal cancer, the median OS from diagnosis of BMs was 4.2  months. Prognostic factors for OS included: ...
Source: Medical Oncology - March 17, 2017 Category: Cancer & Oncology Source Type: research

Identification of trunk mutations in gastric carcinoma: a case study
Intratumor heterogeneity (ITH) poses an urgent challenge for cancer precision medicine because it can cause drug resistance against cancer target therapy and immunotherapy. The search for trunk mutations that ...
Source: BMC Medical Genomics - July 17, 2017 Category: Genetics & Stem Cells Authors: Zhan Zhou, Shanshan Wu, Jun Lai, Yuan Shi, Chixiao Qiu, Zhe Chen, Yufeng Wang, Xun Gu, Jie Zhou and Shuqing Chen Source Type: research

The Short Isoform of Nuclear Mitotic Apparatus Protein 1 Functions as a Putative Tumor Suppressor.
CONCLUSIONS: Short isoform of NuMA might be functioned as a putative role of tumor suppressor. Further studies should be made to illuminate the relationship between ACTN4, MYBL2, and tumor progression. PMID: 28748856 [PubMed - in process]
Source: Chinese Medical Journal - July 28, 2017 Category: General Medicine Authors: Qin WS, Wu J, Chen Y, Cui FC, Zhang FM, Lyu GT, Zhang HM Tags: Chin Med J (Engl) Source Type: research

The role of mmu ‐miR‐155‐5p‐NF‐κB signaling in the education of bone marrow‐derived mesenchymal stem cells by gastric cancer cells
In this study, we observed that miR‐155‐5p is not the sole miRNA mediating gastric cancer cells educating BM‐MSCs, but its downstream NF‐κB signaling is indispensable for this process. Our findings give a deeper insight into the role of miR‐155‐5p in the education of BM‐MSCs by gastric cancer cells and will provide new directions for exploring more miRNAs to elucidate the mechanism of this process.
Source: Cancer Medicine - February 14, 2018 Category: Cancer & Oncology Authors: Mei Wang, Fang Yang, Rong Qiu, Mengchu Zhu, Huiling Zhang, Wenrong Xu, Bo Shen, Wei Zhu Tags: Original Research Source Type: research

Inhibitory Effect of Artesunate on Growth and Apoptosis of Gastric Cancer Cells
The present study aimed to explore the inhibitory effect of artesunate on the growth and apoptosis of gastric cancer cells, in order to search for high effective and low toxic anti-gastric cancer drugs.
Source: Archives of Medical Research - March 12, 2018 Category: Research Authors: Lei Wang, Liang Liu, Jing Wang, YueTong Chen Tags: Original Article Source Type: research

Evaluation and Monitoring of Superoxide Dismutase (SOD) Activity and its Clinical Significance in Gastric Cancer: A Systematic Review and Meta-Analysis.
CONCLUSIONS Meta-analysis showed that SOD measurements from blood samples, especially in erythrocytes, had potential as a diagnostic and monitoring parameter in patients with gastric cancer. PMID: 30886134 [PubMed - in process]
Source: Medical Science Monitor - March 21, 2019 Category: Research Tags: Med Sci Monit Source Type: research

Radiomics approaches in gastric cancer: a frontier in clinical decision making.
CONCLUSIONS: Radiomics holds great potential in facilitating decision-making in gastric cancer. With the standardization of work-flow and advancement of machine learning methods, radiomics is expected to make great breakthroughs in precision medicine of gastric cancer. PMID: 31348029 [PubMed - as supplied by publisher]
Source: Chinese Medical Journal - July 23, 2019 Category: General Medicine Authors: Wang Y, Jin ZY Tags: Chin Med J (Engl) Source Type: research

Circular RNA circ-PRKCI promotes cell proliferation and invasion by binding to microRNA-545 in gastric cancer.
CONCLUSIONS: Circ-PRKCI can be used as a potential prognostic indicator of GC, providing a new perspective for the potential bio-molecular mechanism in GC. PMID: 31773680 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - November 28, 2019 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research

Cellular mesenchymal epithelial transition (C-MET) gene copy number variation in gastric adenocarcinoma: A pilot search for new marker for targeted therapy in HER-2/neu resistance.
Abstract Increasing HER-2/neu resistance in gastric carcinoma has encouraged search for new biomarkers for targeted therapy. Cellular mesenchymal epithelial transition (C-MET) is one such tyrosine kinase inhibitor proposed for personalized salvage treatment. We determined frequency of C-MET gene copy number variation (CNV) by Fluorescent in-situ hybridization (FISH) in gastric adenocarcinoma (GAC) and sought its correlation with conventional clinicopathologic parameters. Dual-coloured FISH was done on 32 GAC cases. C-MET gene and centromere 7 signals were counted under fluorescent microscope and ratio was calculat...
Source: Indian Journal of Pathology and Microbiology - December 31, 2019 Category: Pathology Authors: Jain P, Wadhwa N, Joshi MK, Jain M, Halder A, Mishra K Tags: Indian J Pathol Microbiol Source Type: research

Aberrant Expression of Gastric Carcinoma High Expressed Transcript 1 is a Diagnostic and Prognostic Biomarker in Human Cancer.
CONCLUSIONS: GHET1 may serve as a potential clinical biomarker and poor survival and high-risk recurrence in cancers. PMID: 32653201 [PubMed - as supplied by publisher]
Source: Journal of the National Medical Association - July 14, 2020 Category: General Medicine Tags: J Natl Med Assoc Source Type: research

Gastric carcinoma and renal cell carcinoma as an atypical presentation of multiple primary malignancies: a  case report and review of the literature
ConclusionGastric carcinoma is the second most frequent neoplasm of the GI tract and the main neoplasm that presents a SPM. MPM screening is recommended in patients with gastric cancer. The clinical discovery of MPM of renal origin is rare and hence the importance of the current report.
Source: Journal of Medical Case Reports - December 2, 2020 Category: General Medicine Source Type: research

Correlation Between High Expression of FOXA2 and Improved Overall Survival in Ovarian Cancer Patients.
CONCLUSIONS Upregulation of the FOXA2 gene was correlated with improved OS in patients with ovarian cancer and it can be used as a prognostic biomarker and potential treatment target. PMID: 33483461 [PubMed - as supplied by publisher]
Source: Medical Science Monitor - January 25, 2021 Category: Research Tags: Med Sci Monit Source Type: research

Utility of Pretreatment Blood Platelet-To-Lymphocyte Ratio in Prediction of Clinical Outcomes and Chemosensitivity in Patients with Advanced Gastric Cancer: A Meta-Analysis
CONCLUSIONS This meta-analysis suggests that high PLR is a risk factor for unfavorable OS, DFS, and chemosensitivity in patients with advanced GC.PMID:35095093 | DOI:10.12659/MSM.933449
Source: Medical Science Monitor - January 31, 2022 Category: Research Authors: Xiulan Peng Wei Zeng Bing Tang Anbing He Min Zhang Renfeng Luo Source Type: research