Reduction of No Reflow with a Loading Dose of Atorvastatin before Primary Angioplasty in Patients with Acute ST Myocardial Infarction
No reflow defined as an altered myocardial reperfusion and failure at microvascular level is a frequent complication in acute myocardial infarction that attenuates beneficial effect of reperfusion therapy leading to poor outcomes. There is not enough evidence to support that previous use of statins improves coronary flow in patients undergoing primary percutaneous coronary intervention (PCI). (Source: Archives of Medical Research)
Source: Archives of Medical Research - November 13, 2018 Category: Research Authors: Rosalba C. Garc Ãa-Méndez, Eduardo Almeida-Gutierrez, Leonor Serrano-Cuevas, Jesús Salvador Sánchez-DÃaz, MartÃn Rosas-Peralta, Jose Alberto Ortega-Ramirez, Jose Antonio Palomo-Villada, Irma Isordia-Salas, Rosa Marisol Alonso-Bravo, Gabriela Borrayo Tags: Preliminary Report Source Type: research
Clinical Interests of Circulating Tumor DNA in Oncology
Genetic alterations in tumors, as predictor of response to targeted-therapies or as prognostic markers, are clinically relevant to determine adequate therapeutic management. Tumor biopsy is currently the golden standard for somatic alterations assessment, but this approach is invasive and does not consider tumor heterogeneity. In various body fluids like plasma, somatic mutations have been identified. Circulating tumor DNA (ctDNA) holds promises in tumor burden monitoring or malignancies early detection. (Source: Archives of Medical Research)
Source: Archives of Medical Research - November 7, 2018 Category: Research Authors: Claire Franczak, Pierre Filhine-Tressarieu, Julien Bros éus, Pauline Gilson, Jean-Louis Merlin, Alexandre Harlé Tags: Review Article Source Type: research
Geniposide and Gentiopicroside Suppress Hepatic Gluconeogenesis via Regulation of AKT-FOXO1 Pathway
Hepatic gluconeogenesis plays an important role in regulating fasting plasma glucose levels and is a target of anti-diabetic drugs. Several kinds of iridoid glucosides exhibit hypoglycemic effect, whereas the mechanism was not clear. (Source: Archives of Medical Research)
Source: Archives of Medical Research - November 5, 2018 Category: Research Authors: Shao-Qing Yang, Ye-Dan Chen, Heng Li, Xian Hui, Wen-Yun Gao Tags: Original Article Source Type: research
Predicting Human miRNA-like Sequences within Human Papillomavirus Genomes
This study presents a prediction of putative miRNA within several Human Papillomavirus (HPV) types by using bioinformatics tools and a strategy based on sequence and structure alignment. Currently, little is known about HPV miRNAs. (Source: Archives of Medical Research)
Source: Archives of Medical Research - November 3, 2018 Category: Research Authors: Denisse A. Guti érrez, Armando Varela-RamÃrez, Miriam RodrÃguez-Esquivel, Mónica G. Mendoza-RodrÃguez, Jorge T. Ayala-Sumuano, David Pineda, EfraÃn Garrido-Guerrero, Florinda Jiménez-Vega, Saúl Aguilar, Miguel Quiñones, MarÃa J. Nambo, Pedro Chà Tags: Original Article Source Type: research
Metabolic Syndrome and Cardiovascular Disease: A Health Challenge in Mexico
Metabolic Syndrome (MetS) is a cluster of risk factors that, taken alone or synergically, are independent predictors of type 2 diabetes and cardiovascular disease (CVD), which are both major public health problems that requires urgent containment actions. Current controversies regarding MetS are focused on ascertain the unifying explanation of molecular and pathophysiological mechanisms originating the syndrome, involving insulin resistance and low-grade chronic inflammation. This review aims to present the clinical relevance of MetS and its complications, as well as the hypotheses addressing its etiopathogenic relation wi...
Source: Archives of Medical Research - October 24, 2018 Category: Research Authors: Antonio Gonzalez-Ch ávez, José Alejandro Chávez-Fernández, Sandra Elizondo-Argueta, Alonso González-Tapia, José Israel León-Pedroza, Cesar Ochoa Tags: Review Article Source Type: research
Diagnosis of Transient/Latent HPV Infections - A Point of View!
Diagnosis of transient/latent HPV infections requires a rethinking of ideas concerning the host virus relationship. With this in mind, we address several concepts, such as mutualism and commensalism, to understand better the different stages of development, in addition to briefly covering current methods of detection. We suggest analyzing molecules related to the innate immune response for earlier diagnosis. (Source: Archives of Medical Research)
Source: Archives of Medical Research - October 24, 2018 Category: Research Authors: Eduardo Perez-Campos Mayoral, Gabriel Mayoral-Andrade, Laura P érez-Campos Mayoral, Socorro Pina Canseco, Ruth MartÃnez Cruz, MarÃa Teresa Hernández-Huerta, Adriana Moreno Rodriguez, Hector A. Cabrera-Fuentes, Eduardo Pérez-Campos Tags: Review Article Source Type: research
Association Studies of HSPA1A and HSPA1L Gene Polymorphisms With Schizophrenia in the Polish Population
Schizophrenia is a severe psychiatric disorder with a strong genetic component. The HSP70 chaperones are particularly interesting in terms of schizophrenia, especially with regard to neurodevelopmental hypothesis, because they are critical regulators in normal neural physiological function as well as in cell stress responses. (Source: Archives of Medical Research)
Source: Archives of Medical Research - October 17, 2018 Category: Research Authors: Malgorzata Kowalczyk, Krzysztof Kucia, Aleksander Owczarek, Renata Suchanek-Raif, Wojciech Merk, Monika Paul-Samojedny, Jan Kowalski Tags: Original Article Source Type: research
Antioxidant Activity and Protective Effect of Carob Honey in CCl4-induced Kidney and Liver Injury
Various honey samples exhibited protective effect against drug and chemical induced toxicity. The study was designed to determine the antioxidant content and activity of carob honey and to investigate its hepato-renal protective effect in carbon tetrachloride (CCl4) induced kidney and liver injury in rats. (Source: Archives of Medical Research)
Source: Archives of Medical Research - October 17, 2018 Category: Research Authors: Redouan El-haskoury, Noori Al-Waili, Zineb Kamoun, Mohamed Makni, Hamza Al-Waili, Badiaa Lyoussi Tags: Original Article Source Type: research
Varicella-Zoster Virus in Cerebrospinal Fluid at Relapses of Multiple Sclerosis is Infective in  Vitro
We have reported the presence of varicella-zoster virus (VZV) DNA and viral particles in the cerebrospinal fluid (CSF) of multiple sclerosis (MS) patients during exacerbation. It is not known whether these viruses are infective. (Source: Archives of Medical Research)
Source: Archives of Medical Research - October 17, 2018 Category: Research Authors: Olivia Hern ández-González, Adolfo MartÃnez-Palomo, Julio Sotelo, Bibiana Chávez-MunguÃa, Graciela Ordoñez, Daniel Talamás-Lara, Benjamin Pineda, José de Jesús Flores-Rivera, Martha Espinosa-Cantellano Tags: Preliminary Report Source Type: research
Synergistic Interaction of Rutin and Silibinin on Human Colon Cancer  Cell Line
Rutin and Silibinin are active flavonoid compounds, well-known for possessing multiple biological activities. We have studied how Rutin and Silibinin in combination modulate wide range intracellular signaling cascades as evidenced by in-vitro research. Data obtained from preclinical studies provide evidence to be supportive to bridge basic and translational studies. (Source: Archives of Medical Research)
Source: Archives of Medical Research - October 9, 2018 Category: Research Authors: Sana Nafees, Syed Hassan Mehdi, Mohammad Zafaryab, Bushra Zeya, Tarique Sarwar, Moshahid Alam Rizvi Tags: Original Article Source Type: research
Response to: Chikungunya in Bolivia: Still a Neglected Disease?
We greatly appreciate the thoughtful comments from the authors (1). We agree with them about the importance of timely and accurate diagnosis and treatment of chikungunya infection. (Source: Archives of Medical Research)
Source: Archives of Medical Research - October 8, 2018 Category: Research Authors: Efr én Murillo-Zamora, Oliver Mendoza-Cano Tags: Letter to the Editor Source Type: research
Vaccination Status and Another Preventive Measures in Medical Schools. Big Needs and Opportunities
Vaccination Status and other Preventive Measures in Medical School. Big Needs and Opportunities, Diana Vilar-Compte, et  al. (1), is a public health priority and one of the many challenges medical schools in Mexico and worldwide face. Our country has a longstanding tradition of highly effective immunization coverage in infancy dating to the nineteen fifties that led to a significant decrease of under five mortality rates. Over the following years, intensive annual vaccination campaigns targeted hard to reach populations in urban and rural areas and the National Immunization Council was created in 1991 (2). (Source: Archiv...
Source: Archives of Medical Research - October 6, 2018 Category: Research Authors: Germ án Fajardo Dolci Tags: Opinion Source Type: research
Vaccination Status and Another Preventive Measures in Medical School. Big Needs and Opportunities
Vaccination Status and other Preventive Measures in Medical School. Big Needs and Opportunities, Diana Vilar-Compte, et  al. (1), is a public health priority and one of the many challenges medical schools in Mexico and worldwide face. Our country has a longstanding tradition of highly effective immunization coverage in infancy dating to the nineteen fifties that led to a significant decrease of under five mortality rates. Over the following years, intensive annual vaccination campaigns targeted hard to reach populations in urban and rural areas and the National Immunization Council was created in 1991 (2). (Source: Archiv...
Source: Archives of Medical Research - October 6, 2018 Category: Research Authors: Germ án Fajardo Dolci Tags: Opinion Source Type: research
Meta-analysis on the Association Between Norepinephrine Transporter Gene rs2242446, rs5569 Polymorphisms and Risk of Major Depressive Disorder
The association between norepinephrine transporter (NET) gene polymorphisms and the risk of major depressive disorder (MDD) has been investigated extensively, but with contradictory findings. (Source: Archives of Medical Research)
Source: Archives of Medical Research - October 3, 2018 Category: Research Authors: Huan Rui, Hongjia Qian, Muhua Shi, Guorui Zhang, Liqun Wang Tags: Original Article Source Type: research
Association Between Norepinephrine Transporter Gene rs2242446, rs5569 Polymorphisms and Risk of Major Depressive Disorder. A Meta-analysis
The association between norepinephrine transporter (NET) gene polymorphisms and the risk of major depressive disorder (MDD) has been investigated extensively, but with contradictory findings. (Source: Archives of Medical Research)
Source: Archives of Medical Research - October 3, 2018 Category: Research Authors: Huan Rui, Hongjia Qian, Muhua Shi, Guorui Zhang, Liqun Wang Tags: Original Article Source Type: research
