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Neonatal erythema multiforme associated with a rotavirus infection: A case report
CONCLUSION: The possibility of rotavirus, a major cause of pediatric gastrointestinal infections, being a trigger for neonatal EM should be considered.PMID:37727716 | PMC:PMC10506005 | DOI:10.12998/wjcc.v11.i24.5749
Source: Herpes - September 20, 2023 Category: Infectious Diseases Authors: Jung Jae Kim Joon Kee Lee Source Type: research
Efficient trapping and destruction of SARS-CoV-2 using PECO-assisted Molekule air purifiers in the laboratory and real-world settings
Ecotoxicol Environ Saf. 2023 Sep 18;264:115487. doi: 10.1016/j.ecoenv.2023.115487. Online ahead of print.ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is transmitted human-to-human via aerosols and air-borne droplets. Therefore, capturing and destroying viruses from indoor premises are essential to reduce the probability of human exposure and virus transmission. While the heating, ventilation, and air conditioning (HVAC) systems help in reducing the indoor viral load, a targeted approach is required to effectively remove SARS-CoV-2 from indoor air to address human exposure concerns. The present study...
Source: Ecotoxicology and Environmental Safety - September 20, 2023 Category: Environmental Health Authors: Arpan Acharya Kerri Surbaugh Michellie Thurman Chatura Wickramaratne Philip Myers Rajat Mittal Kabita Pandey Elizabeth Klug Sarah J Stein Ashley R Ravnholdt Vicki L Herrera Danielle N Rivera Paul Williams Joshua L Santarpia Ajeet Kaushik Jaspreet S Dhau S Source Type: research
HPC-Atlas: Computationally Constructing A Comprehensive Atlas of Human Protein Complexes
Genomics Proteomics Bioinformatics. 2023 Sep 18:S1672-0229(23)00103-1. doi: 10.1016/j.gpb.2023.05.001. Online ahead of print.ABSTRACTA fundamental principle of biology is that proteins tend to form complexes to play significant roles in the core functions of cells. For a complete understanding of human cellular functions, it is crucial to have a comprehensive atlas of human protein complexes. Unfortunately, we still lack such a comprehensive atlas of experimentally validated protein complexes, which prevents us from gaining a complete understanding of the compositions and functions of human protein complexes and biological...
Source: Genomics Proteomics ... - September 20, 2023 Category: Genetics & Stem Cells Authors: Yuliang Pan Ruiyi Li Wengen Li Liuzhenghao Lv Jihong Guan Shuigeng Zhou Source Type: research
Neonatal erythema multiforme associated with a rotavirus infection: A case report
CONCLUSION: The possibility of rotavirus, a major cause of pediatric gastrointestinal infections, being a trigger for neonatal EM should be considered.PMID:37727716 | PMC:PMC10506005 | DOI:10.12998/wjcc.v11.i24.5749
Source: Herpes - September 20, 2023 Category: Infectious Diseases Authors: Jung Jae Kim Joon Kee Lee Source Type: research
The Pathogenesis of COVID-19-Related Taste Disorder and Treatments
J Dent Res. 2023 Sep 20:220345231182926. doi: 10.1177/00220345231182926. Online ahead of print.ABSTRACTCOVID-19, mainly manifested as acute respiratory distress syndrome, has afflicted millions of people worldwide since 2019. Taste dysfunction is a common early-stage symptom of COVID-19 infection that burdens patients for weeks or even permanently in some cases. Owing to its subjectivity and complexity, the mechanism of taste disorder is poorly studied. Previous studies have reported that the COVID-19 entry receptors are highly expressed in taste buds, thereby intensifying the cytocidal effect. Taste receptor cells are vul...
Source: Cell Research - September 20, 2023 Category: Cytology Authors: J Wang R Liu H Ma W Zhang Source Type: research
Cinnamaldehyde inhibits cytokine storms induced by the ORF3a protein of SARS-CoV-2 via ROS-elimination in activated T cells
Phytother Res. 2023 Sep 19. doi: 10.1002/ptr.8016. Online ahead of print.ABSTRACTCytokine storms are the cause of complications in patients with severe COVID-19, and it becomes the target of therapy. Several natural compounds were selected to screen the inhibitory effect on T-cell proliferation by Fluorescence-Activated Cell Sorting (FACS) and cytokine production by enzyme-linked immunosorbent assay (ELISA). Open reading frame 3a (ORF3a) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) stimulates the specific T-cell activation model in vivo and in vitro. The coculture system included the macrophage cell line...
Source: Cell Research - September 20, 2023 Category: Cytology Authors: Jing Ma Xu Chen Rui Xue Fei Wang Jun Dong Ning Tao Zhihai Qin Source Type: research
Necessary to Identify Latent Toxicants A
Dear Editor SARS ‑CoV‑2 is a new coronavirus that emerged in 2019 and caused the COVID‑19 epidemic, but despite much effort, there is still no specific care standard. The lack of accurate information posed several challenges for health systems, which were accompanied by a wide range of possibly unfamiliar mate rials for the treatment and prevention of COVID‑19.[1] When a major medical crisis such as COVID‑19 occurs, and there is no known cure for it, several phenomena may occur, and people to show different behavioral reactions to deal with this condition and treat it with limited knowledge.
Source: International Journal of Preventive Medicine - September 20, 2023 Category: International Medicine & Public Health Source Type: research
Immune monitoring of SARS-CoV-2-specific T cell and B cell responses in patients with multiple sclerosis treated with ocrelizumab
DiscussionOur results call for a critical discussion regarding appropriate vaccination intervals and potential biomarkers for the prediction of (re)infection with SARS-CoV-2 in patients with MS receiving ocrelizumab.Unique identifierDRKS00029110; URL: http://apps.who.int/trialsearch/.
Source: Frontiers in Immunology - September 20, 2023 Category: Allergy & Immunology Source Type: research
SARS-COV-2 pandemic and child abuse - Chinchilla Langeber S, Bay ón Cabanes M.
With the advent of coronavirus disease 2019 (COVID-19), countries had to make drastic and unexpected decisions for their populations. The Spanish government declared the state of alarm (14/03/2020-21/06/2020) and imposed strict measures (home confinement, ...
Source: SafetyLit - September 19, 2023 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news
How does the Immunological System Change during the SARS-COV-2 Attack? A Clue for the New Immunotherapy Discovery
Curr Med Chem. 2023 Sep 18. doi: 10.2174/0929867331666230918092749. Online ahead of print.ABSTRACTThe COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-COV-2) is one of the biggest unsolved global problems of the 21st century for which there has been no definitive cure yet. Like other respiratory viruses, SARS-COV-2 triggers the host immunity dramatically, causing dysfunction in the immune system, both innate and adaptive, which is a common feature of COVID-19 patients. Evidence shows that in the early stages of COVID-19, the immune system is suppressed while it is overactive in severe p...
Source: Current Medicinal Chemistry - September 19, 2023 Category: Chemistry Authors: Mohammad Mahdi Hajihasani Najmeh Kaffash Farkhad Ali Mahmoudi Amirhossein Sahebkar Source Type: research
Salivette ® Cortisol versus oropharyngeal swabbing for the detection of SARS-CoV-2 infection
CONCLUSIONS: The SC may be an alternative for SARS-CoV-2 detection where naso/oropharyngeal swabbing is not feasible/available. This technique also confirms observations that the detection of SARS-CoV-2 in the upper airway may vary due to viral load over the disease course.TRIAL REGISTRATION: NCT04599959.PMID:37724431 | DOI:10.1080/14737159.2023.2260308
Source: Expert Review of Molecular Diagnostics - September 19, 2023 Category: Laboratory Medicine Authors: Petra Moroni-Zentgraf Christoph Keller Christoph C Eschenfelder Hanns Walter M üller Ralf Sigmund David Galeana-Cadena Jos é Eduardo Márquez-García Ang élica Moncada-Morales Joaquin A Z úñiga Source Type: research
Clinical Utility of Sero-Immunological Responses Against SARS-CoV-2 Nucleocapsid Protein During Subsequent Prevalence of Wild-Type, Delta Variant, and Omicron Variant
In conclusion, nucleocapsid antibody provides instructive clues about the immunogenicity of nucleocapsid proteins by different seroconversion rates and titers according to the severity of infection, host immune status, and different variants of concern.PMID:37724496 | DOI:10.3346/jkms.2023.38.e292
Source: Journal of Korean Medical Science - September 19, 2023 Category: Biomedical Science Authors: Beomki Lee Jae-Hoon Ko Jin Yang Baek Haein Kim Kyungmin Huh Sun Young Cho Cheol-In Kang Doo Ryeon Chung Kyong Ran Peck Eun-Suk Kang Source Type: research
How does the Immunological System Change during the SARS-COV-2 Attack? A Clue for the New Immunotherapy Discovery
Curr Med Chem. 2023 Sep 18. doi: 10.2174/0929867331666230918092749. Online ahead of print.ABSTRACTThe COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-COV-2) is one of the biggest unsolved global problems of the 21st century for which there has been no definitive cure yet. Like other respiratory viruses, SARS-COV-2 triggers the host immunity dramatically, causing dysfunction in the immune system, both innate and adaptive, which is a common feature of COVID-19 patients. Evidence shows that in the early stages of COVID-19, the immune system is suppressed while it is overactive in severe p...
Source: Current Medicinal Chemistry - September 19, 2023 Category: Chemistry Authors: Mohammad Mahdi Hajihasani Najmeh Kaffash Farkhad Ali Mahmoudi Amirhossein Sahebkar Source Type: research
